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Article Count - 153
Cumulative Knowledge - 612

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View the Evidence: Substances

A flaxseed-derived lignan supplement has therapeutic value in type 2 diabetics.

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Pubmed Data : PLoS One. 2007 Nov 7;2(11):e1148. PMID: 17987126

Article Published Date : Nov 07, 2007

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57), Lignans : CK(110) : AC(31)

Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341)

A flaxseed-derived lignan supplement may reduce C-reactive protein in type 2 diabetics.

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2009 Apr;101(8):1145-9. PMID: 18775100

Article Published Date : Apr 01, 2009

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Diabetes: Cardiovascular Illness : CK(666) : AC(104), Elevated CRP : CK(72) : AC(8)

A hemp seed containing proprietary Chinese herbal medicine alleviates symptoms of functional constipation.

Click here to read the entire abstract

Pubmed Data : Am J Gastroenterol. 2010 Nov 2. Epub 2010 Nov 2. PMID: 21045817

Article Published Date : Nov 02, 2010

Study Type : Human Study

Additional Links

Substances : Hemp Seed : CK(18) : AC(5)

Diseases : Constipation : CK(316) : AC(36)

Adherence to a diet comprising mostly fruits, vegetables, fish, and olive/sunflower oil, along with avoidance of Western-type foods, may contribute to a substantial reduction in postmenopausal breast cancer risk.

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Pubmed Data : Am J Epidemiol. 2009 Nov 15;170(10):1257-67. Epub 2009 Oct 14. PMID: 19828509

Article Published Date : Nov 15, 2009

Study Type : Human Study

Additional Links

Substances : Fruit: All : CK(1836) : AC(472), Olive : CK(401) : AC(97), Sunflower Seeds : CK(10) : AC(1), Vegetables: All : CK(551) : AC(69)

Diseases : Breast Cancer : CK(2354) : AC(621)

Therapeutic Actions : Dietary Modification: Non-Western Diet : CK(40) : AC(4)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

An herbal combination of saffron, celery seed and anise is more effective than the drug mefenamic acid (NSAID) in relieving menstrual pain.

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Pubmed Data : J Midwifery Womens Health. 2009 Sep-Oct;54(5):401-4. PMID: 19720342

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Anise : CK(29) : AC(8), Celery seed : CK(20) : AC(7), Saffron : CK(135) : AC(34)

Diseases : Dysmenorrhea : CK(409) : AC(26)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Black cumin (Nigella sativa) and Phyllanthus niruri provide symptomatic relief in the treatment of acute tonsillo-pharyngitis patients.

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Pubmed Data : Int J Clin Pharmacol Ther. 2008 Jun;46(6):295-306. PMID: 18541126

Article Published Date : Jun 01, 2008

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34), Phyllanthus niruri (Stonebreaker) : CK(21) : AC(9)

Diseases : Pharyngitis : CK(30) : AC(3), Tonsillitis : CK(40) : AC(4)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Black cumin (Nigella sativa) has a prophylactic effect on chemical war victims.

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Pubmed Data : J Altern Complement Med. 2008 Nov;14(9):1137-44. PMID: 18991514

Article Published Date : Nov 01, 2008

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)

Diseases : Chemical Weapon Agent Injury : CK(14) : AC(4)

Black cumin (Nigella sativa) is effective in long-term treatment of opioid dependence.

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Pubmed Data : J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):118-24. PMID: 19385474

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)

Diseases : Opiate Addiction/Withdrawal : CK(64) : AC(14)

Black cumin alleviates symptoms of allergic rhinitis.

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Pubmed Data : Am J Otolaryngol. 2010 Oct 12. Epub 2010 Oct 12. PMID: 20947211

Article Published Date : Oct 12, 2010

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)

Diseases : Allergic Rhinitis : CK(318) : AC(40)

Black cumin possesses clinical useful anti-H. pylori activity compared to triple therapy.

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Pubmed Data : Saudi J Gastroenterol. 2010 Jul-Sep;16(3):207-14. PMID: 20616418

Article Published Date : Jul 01, 2010

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)

Diseases : Dyspepsia : CK(422) : AC(21), Helicobacter Pylori Infection : CK(305) : AC(61)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316), Anti-Ulcer Agents : CK(162) : AC(57)

Additional Keywords : Drug: Amoxicillin : CK(60) : AC(6), Drug: Omeprazole : CK(90) : AC(15), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268), Natural Substances Versus Drugs : CK(988) : AC(165), Plant Extracts : CK(3572) : AC(1216)

Black cumin seeds have significant anti-diabetic effects in type 2 diabetics.

Click here to read the entire abstract

Pubmed Data : Indian J Physiol Pharmacol. 2010 Oct-Dec;54(4):344-54. PMID: 21675032

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)

Diseases : A1C : CK(253) : AC(35), Diabetes: Glycation/A1C : CK(186) : AC(33), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Insulin Resistance : CK(1034) : AC(221)

Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156), Insulin Sensitizers : CK(167) : AC(36)

Additional Keywords : Beta Cell Protection : CK(53) : AC(22), Beta Cell Regeneration : CK(60) : AC(24)

Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk.

Click here to read the entire abstract

Pubmed Data : Cancer Causes Control. 2013 Jan 25. Epub 2013 Jan 25. PMID: 23354422

Article Published Date : Jan 24, 2013

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Breast Cancer: Prevention : CK(525) : AC(73)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Dietary addition of 25 g flaxseed per day results in significantly increased levels of IL-1Ra, an endogenous inhibitor of the proinflammatory IL-1α and IL-1β.

Click here to read the entire abstract

Pubmed Data : J Clin Endocrinol Metab. 2012 Aug 28. Epub 2012 Aug 28. PMID: 22930784

Article Published Date : Aug 27, 2012

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Interleukin 1 receptor antagonist (IL-1Ra) up-regulation : CK(10) : AC(1)

Dietary flaxseed lignan improves lower urinary tract symptoms in benign prostatic hyperplasia subjects as well as drug therapy.

Click here to read the entire abstract

Pubmed Data : J Ren Nutr. 2007 Jan;17(1):23-9. PMID: 18358071

Article Published Date : Jan 01, 2007

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Prostatic Hyperplasia: Benign : CK(202) : AC(46)

Additional Keywords : Natural Substances Versus Drugs : CK(988) : AC(165), Secoisolariciresinol Diglucoside : CK(10) : AC(1)

Dietary flaxseed may reduce tumor growth in patients with breast cancer.

Click here to read the entire abstract

Pubmed Data : Clin Cancer Res. 2005 May 15;11(10):3828-35. PMID: 15897583

Article Published Date : May 15, 2005

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Breast Cancer : CK(2354) : AC(621)

Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients.

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2007 Oct;61(10):1201-6. Epub 2007 Jan 31. PMID: 17268413

Article Published Date : Oct 01, 2007

Study Type : Human Study

Additional Links

Substances : ALA (Alpha-Linolenic Acid) : CK(48) : AC(8), Flaxseed : CK(275) : AC(57)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Dyslipidemias : CK(176) : AC(33)

Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Flaxseed and borage oil supplementation increases skin hydration in women.

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2009 Feb;101(3):440-5. Epub 2008 Sep 2. PMID: 18761778

Article Published Date : Feb 01, 2009

Study Type : Human Study

Additional Links

Substances : Borage Oil : CK(54) : AC(8), Flaxseed : CK(275) : AC(57), Omega-3 Fatty Acids : CK(3333) : AC(319)

Diseases : Dry Skin : CK(86) : AC(13)

Flaxseed dietary fiber supplements suppress appetite and food intake.

Click here to read the entire abstract

Pubmed Data : Appetite. 2012 Jan 5. Epub 2012 Jan 5. PMID: 22245724

Article Published Date : Jan 05, 2012

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Appetite Disorders : CK(105) : AC(13), Weight Probems: Appetite : CK(122) : AC(16)

Flaxseed lignan has therapeutic value in the treatment of metabolic syndrome in men.

Click here to read the entire abstract

Pubmed Data : Appl Physiol Nutr Metab. 2009 Apr;34(2):89-98. PMID: 19370038

Article Published Date : Apr 01, 2009

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Metabolic Syndrome X : CK(645) : AC(122)

Flaxseed may reduce circulating total and LDL-cholesterol levels.

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2009 Aug;90(2):288-97. Epub 2009 Jun 10. PMID: 19515737

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57), Lignans : CK(110) : AC(31)

Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), High Cholesterol : CK(1718) : AC(198)

Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)

Flaxseed meal and flaxseed extract is effective in reducing menopausal symptoms without increasing blood levels of follicle stimulating hormone and estradiol, as well as in the endometrial thickness, and vaginal epithelial maturation value.

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Pubmed Data : J Med Food. 2012 Sep ;15(9):840-5. PMID: 22925074

Article Published Date : Aug 31, 2012

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57), Secoisolariciresinol diglucoside (SDG) : CK(387) : AC(5)

Diseases : Hot Flash : CK(203) : AC(19), Menopausal Syndrome : CK(171) : AC(27)

Flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition.

Click here to read the entire abstract

Pubmed Data : Skin Pharmacol Physiol. 2010 Nov 18;24(2):67-74. Epub 2010 Nov 18. PMID: 21088453

Article Published Date : Nov 18, 2010

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Aging Skin : CK(360) : AC(86), Dry Skin : CK(86) : AC(13), Skin Diseases : CK(46) : AC(9)

Flaxseed supplementation and a low-fat diet reduces proliferation of benign prostatic epithelium and PSA.

Click here to read the entire abstract

Pubmed Data : Urology. 2004 May;63(5):900-4. PMID: 15134976

Article Published Date : May 01, 2004

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Prostate: PSA Doubling : CK(133) : AC(16), Prostatic Hyperplasia: Benign : CK(202) : AC(46)

Flaxseed supplementation appears to be renoprotective in lupus nephritis.

Click here to read the entire abstract

Pubmed Data : J Am Coll Nutr. 2001 Apr;20(2 Suppl):143-8. PMID: 11349937

Article Published Date : Apr 01, 2001

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Lupus Nephritis : CK(64) : AC(12)

Flaxseed supplementation reduces prostate cancer proliferation rates in men presurgery.

Click here to read the entire abstract

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3577-87. PMID: 19064574

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Prostate Cancer : CK(998) : AC(288)

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