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Sesamol

Sesamol

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Article Count - 30
Cumulative Knowledge - 54

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View the Evidence: Substances

Sesamin may prevent the development of atherosclerosis and inflammatory responses

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2010 Sep ;54(9):1340-50. PMID: 20306475

Article Published Date : Sep 01, 2010

Study Type : Animal Study

Additional Links

Substances : Lignans : CK(110) : AC(31), Sesamol : CK(79) : AC(30)

Diseases : Atherosclerosis : CK(523) : AC(77), Endothelial Dysfunction : CK(897) : AC(173)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1383) : AC(115)

Sesamol attenuates diabetes-associated cognitive decline in rats.

Click here to read the entire abstract

Pubmed Data : Exp Brain Res. 2008 Mar ;185(3):411-20. Epub 2007 Oct 23. PMID: 17955223

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Diabetes: Cognitive Dysfunction : CK(35) : AC(12), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Sesamol attenuates diclofenac-induced acute gastric mucosal injury.

Click here to read the entire abstract

Pubmed Data : Shock. 2008 Oct ;30(4):456-62. PMID: 18277948

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Gastric Ulcer : CK(246) : AC(91), Inflammation : CK(1077) : AC(363), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318), Cyclooxygenase Inhibitors : CK(64) : AC(32), Gastroprotective : CK(62) : AC(31)

Problem Substances : Diclofenac : CK(72) : AC(7)

Adverse Pharmacological Actions : Irritant : CK(49) : AC(9)

Sesamol attenuates experimentally induced Huntington-like changes in an animal model.

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Pubmed Data : J Asian Nat Prod Res. 2009 ;11(5):439-50. PMID: 19504387

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Huntington Disease : CK(45) : AC(17)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Sesamol attenuates experimentally induced myocardial infarction.

Click here to read the entire abstract

Pubmed Data : Cell Physiol Biochem. 2011 ;27(3-4):273-80. Epub 2011 Apr 1. PMID: 21471716

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Hypertension : CK(2783) : AC(271), Myocardial Infarction : CK(2632) : AC(117)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(49) : AC(30)

Sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome.

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Pubmed Data : Cell Biochem Biophys. 2011 Jun 17. Epub 2011 Jun 17. PMID: 21681587

Article Published Date : Jun 17, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Sinusoidal obstruction syndrome : CK(2) : AC(1)

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(49) : AC(30)

Sesamol attenuates the renoinflammatory cascade in experimental model of diabetic nephropathy.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2009 Jul 22 ;57(14):6123-8. PMID: 19601660

Article Published Date : Jul 22, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Kidney Damage : CK(120) : AC(42), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318), Apoptotic : CK(1489) : AC(1114), Renoprotective : CK(191) : AC(90)

Sesamol delays mortality and attenuates liver injury.

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Pubmed Data : Shock. 2006 May ;25(5):528-32. PMID: 16680019

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Liver Damage : CK(597) : AC(213), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Sesamol exhibits anti-depressant properties.

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Pubmed Data : Psychopharmacology (Berl). 2011 Apr ;214(4):819-28. Epub 2010 Nov 20. PMID: 21103863

Article Published Date : Apr 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Depression : CK(674) : AC(88), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Antidepressive Agents : CK(142) : AC(31), Catalase Up-Regulation : CK(22) : AC(8), Glutathione Upregulation : CK(144) : AC(48), Superoxide Dismutase Up-regulation : CK(131) : AC(42)

Sesamol has neuroprotective properties.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2011 Jun 1 ;659(2-3):177-86. Epub 2011 Apr 2. PMID: 21463622

Article Published Date : Jun 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Brain Damage : CK(89) : AC(41), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Enzyme Inhibitors : CK(372) : AC(208), Neuroprotective Agents : CK(962) : AC(480), Nitric Oxide Inhibitor : CK(108) : AC(57), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Sesamol has radioprotective properties.

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Pubmed Data : Environ Toxicol Pharmacol. 2009 Sep ;28(2):192-7. Epub 2009 Apr 11. PMID: 21784002

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Oxidative Stress : CK(1945) : AC(710), Radiation Disaster Associated Toxicity : CK(957) : AC(274)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(456) : AC(183)

Sesamol has therapeutic value in ovariectomy-induced pathophysiological changes.

Click here to read the entire abstract

Pubmed Data : Climacteric. 2012 Sep 27. Epub 2012 Sep 27. PMID: 23017032

Article Published Date : Sep 26, 2012

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Memory Impairment: Hormone Deficiency Induced : CK(24) : AC(9), Menopausal Syndrome : CK(171) : AC(27), Postmenopausal Disorders: Memory Impairment : CK(24) : AC(10)

Additional Keywords : Ovariectomy-Induced Changes : CK(52) : AC(22)

Sesamol has wound healing properties.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2011 Jan 27 ;133(2):608-12. Epub 2010 Oct 28. PMID: 21035533

Article Published Date : Jan 27, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Wound Healing : CK(235) : AC(72)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Science Confirms Tradition : CK(72) : AC(49)

Problem Substances : Dexamethasone : CK(49) : AC(8)

Sesamol improves blood-brain-barrier function in diabetic rats.

Click here to read the entire abstract

Pubmed Data : Exp Brain Res. 2009 Jul ;197(1):23-34. Epub 2009 Jun 30. PMID: 19565232

Article Published Date : Jul 01, 2009

Study Type : Transgenic Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Blood-Brain-Barrier Disorders : CK(25) : AC(15), Diabetes: Cognitive Dysfunction : CK(35) : AC(12), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Sesamol protects against acetaminophen-induced injury in animals.

Click here to read the entire abstract

Pubmed Data : Shock. 2009 Jul ;32(1):89-93. PMID: 18948843

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Acetaminophen (Tylenol) Toxicity : CK(100) : AC(26), Chemically-Induced Liver Damage : CK(475) : AC(175), Lipid Peroxidation : CK(403) : AC(127), Liver Damage : CK(597) : AC(213), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272)

Problem Substances : Tylenol : CK(125) : AC(13)

Adverse Pharmacological Actions : Hepatotoxic : CK(283) : AC(80), Oxidant : CK(104) : AC(37)

Sesamol protects against chemically-induced acute kidney injury in mice.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2008 Aug ;46(8):2736-41. Epub 2008 Apr 29. PMID: 18539378

Article Published Date : Aug 01, 2008

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Kidney Damage : CK(120) : AC(42), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Sesamol protects against chemically-induced liver damage in rats.

Click here to read the entire abstract

Pubmed Data : Yakugaku Zasshi. 1994 Nov ;114(11):901-10. PMID: 7853152

Article Published Date : Nov 01, 1994

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Liver Damage : CK(597) : AC(213)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Sesamol protects against chemically-induced oxidative renal injury in rats.

Click here to read the entire abstract

Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Apr ;104(4):316-21. Epub 2009 Feb 27. PMID: 19281599

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Kidney Damage : CK(120) : AC(42), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Glutathione Upregulation : CK(144) : AC(48), Renoprotective : CK(191) : AC(90), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Sesamol protects against cognitive dysfunction and altered glutathione redox balance.

Click here to read the entire abstract

Pubmed Data : Basic Clin Pharmacol Toxicol. 2010 Jul ;107(1):577-82. Epub 2010 Jan 25. PMID: 20102363

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Cognitive Decline/Dysfunction : CK(522) : AC(87), Huntington Disease : CK(45) : AC(17), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Sesamol protects against myocardial infarction.

Click here to read the entire abstract

Pubmed Data : Redox Rep. 2010 ;15(1):36-42. PMID: 20196927

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Myocardial Infarction: Prevention : CK(54) : AC(3)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Glutathione Upregulation : CK(144) : AC(48), Mitochondrial Superoxide Dismutase Upregulation : CK(4) : AC(3)

Sesamol protects against radiation-induced cytotoxicity in mice.

Click here to read the entire abstract

Pubmed Data : Mutat Res. 2006 Dec 10 ;611(1-2):9-16. Epub 2006 Oct 11. PMID: 17045515

Article Published Date : Dec 10, 2006

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Radiation Induced Illness : CK(1018) : AC(249)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(456) : AC(183)

Sesamol reduces pulmonary inflammatory response and lung injury in endotoxemic rats.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2010 Jul ;48(7):1821-6. Epub 2010 Apr 14. PMID: 20398721

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Endotoxemia : CK(187) : AC(40), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128), Lung Infection : CK(365) : AC(3), Lung Injury: Acute : CK(32) : AC(11), Respiratory Infections : CK(425) : AC(48)

Pharmacological Actions : NF-kappaB Inhibitor : CK(595) : AC(401), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Sesamol suppresses neuropathic pain associated with diabetes.

Click here to read the entire abstract

Pubmed Data : J Pain. 2010 Oct ;11(10):950-7. Epub 2010 Apr 24. PMID: 20418182

Article Published Date : Oct 01, 2010

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Diabetic Neuropathies : CK(203) : AC(32), Inflammation : CK(1077) : AC(363), Neuropathic Pain : CK(157) : AC(24)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Caspase-3 Inhibition : CK(4) : AC(2)

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1383) : AC(115)

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2011 Apr 13 ;59(7):3214-9. Epub 2011 Mar 10. PMID: 21391595

Article Published Date : Apr 13, 2011

Study Type : In Vitro Study

Additional Links

Substances : Lignans : CK(110) : AC(31), Sesame Seeds : CK(151) : AC(27), Sesamol : CK(79) : AC(30)

Diseases : Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Review: Sesamol has significant antioxidant properties.

Click here to read the entire abstract

Pubmed Data : Med Chem. 2009 Jul ;5(4):367-71. PMID: 19689394

Article Published Date : Jul 01, 2009

Study Type : Review

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Related Blogs

Open Sesame! 10 Amazing Health Benefits Of This Super-Seed

Written by Sayer Ji, Founder

Sesame (Sesamun indicum) is one of the oldest cultivated plants in the world, prized as an oilseed for at least 5,000 years. While it is beginning to regain favor due to its exceptionally high calcium and magnesium content, few realize it is also one of the most potent medicinal foods still commonly consumed today.

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