Silymarin

Silymarin

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Article Count - 8
Cumulative Knowledge - 56

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Quick Summary: Current access displays 2 out of 9 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Colorectal Cancer	10	1	Log in \| Sign up
Liver Cancer	10	1	Log in \| Sign up

Quick Summary: Current access displays 2 out of 9 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Radioprotective	11	2	Log in \| Sign up
Anticarcinogenic Agents	10	1	Log in \| Sign up

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View the Evidence: Substances

"Protective effect of silymarin during coronary artery bypass grafting surgery."

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Clin Cardiol. 2012 ;17(1):34-8. PMID: 23204899

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Substances : Silymarin : CK(36) : AC(8)

Diseases : Coronary Bypass Surgery : CK(100) : AC(10)

A silymarin-based cream may be a promising and effective treatment for the prevention of acute skin lesions caused by radiotherapy of breast cancer patients.

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Pubmed Data : Strahlenther Onkol. 2011 Aug ;187(8):485-91. Epub 2011 Jul 22. PMID: 21786113

Article Published Date : Aug 01, 2011

Study Type : Human Study

Additional Links

Substances : Silymarin : CK(36) : AC(8)

Diseases : Radiodermatitis : CK(10) : AC(1)

Pharmacological Actions : Radioprotective : CK(456) : AC(183)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Oral silibinin, an IGF-1 binder, may result in lowered IGF-1 levels in liver and colorectal cancer patients as indicated by its accumulation in blood and tissue samples.

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Pubmed Data : Clin Cancer Res. 2006 May 1;12(9):2944-50. PMID: 16675592

Article Published Date : May 01, 2006

Study Type : Human Study

Additional Links

Substances : Milk Thistle : CK(226) : AC(55), Silibinin : CK(58) : AC(10), Silymarin : CK(36) : AC(8)

Diseases : Colorectal Cancer : CK(877) : AC(321), Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Insulin-Like Growth Factor Inhibition/Downregulation : CK(66) : AC(16)

Silymarin and selenium are safe and effective in reducing two markers of lipid metabolism associated with prostate cancer progression after radical prostatectomy.

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Pubmed Data : Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Sep;154(3):239-44. PMID: 21048810

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Substances : Selenium : CK(574) : AC(94), Silymarin : CK(36) : AC(8)

Diseases : Prostate Cancer: Surgery : CK(10) : AC(1)

Silymarin is effective in reduced ALT and AST in NAFLD.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Hepat Mon. 2012 Aug ;12(8):e6099. Epub 2012 Aug 3. PMID: 23087748

Article Published Date : Jul 31, 2012

Study Type : Human Study

Additional Links

Substances : Silymarin : CK(36) : AC(8)

Diseases : AST: Elevated : CK(26) : AC(4), Elevated: ALT : CK(23) : AC(2), Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)

Curcumin, silymarin and N-acetylcysteine protect against antitubercular drug-induced hepatotoxicity.

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Pubmed Data : Hum Exp Toxicol. 2012 Feb 8. Epub 2012 Feb 8. PMID: 22318308

Article Published Date : Feb 08, 2012

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), NAC (N-acetyl-L-cysteine) : CK(264) : AC(62), Silymarin : CK(36) : AC(8)

Diseases : Tubercolosis Drug Induced Toxicity : CK(26) : AC(9)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Problem Substances : Tubercular Drugs : CK(2) : AC(1)

A number of plant polyphenols have chemosensitizing and radiosensitizing activity.

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Pubmed Data : Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1630-47. PMID: 16356126

Article Published Date : Nov 01, 2005

Study Type : Review

Additional Links

Substances : Betulinic acid : CK(6) : AC(6), Caffeic acid phenethyl ester : CK(15) : AC(8), Curcumin : CK(2910) : AC(1482), Emodin : CK(32) : AC(19), Flavonoids : CK(909) : AC(289), Genistein : CK(450) : AC(174), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174), Resveratrol : CK(977) : AC(590), Silymarin : CK(36) : AC(8), Ursolic Acid : CK(18) : AC(12)

Diseases : Cancers: Drug Resistant : CK(225) : AC(147)

Pharmacological Actions : Chemosensitizer : CK(197) : AC(159), Radiosensitizer : CK(50) : AC(29)

Beta glucan and silymarin may protect against depleted uranium associated toxicity.

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Pubmed Data : Hum Exp Toxicol. 2011 Mar;30(3):173-81. Epub 2010 Jun 3. PMID: 20522489

Article Published Date : Mar 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Beta-glucan : CK(225) : AC(40), Silymarin : CK(36) : AC(8)

Diseases : Uranium Poisoning : CK(28) : AC(19)

Pharmacological Actions : Radioprotective : CK(456) : AC(183)

Silymarin inhibits endothelial progenitor cell aging through telomerase upregulation.

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Pubmed Data : Life Sci. 2002 Aug 9;71(12):1385-96. PMID: 20838231

Article Published Date : Aug 09, 2002

Study Type : In Vitro Study

Additional Links

Substances : Silymarin : CK(36) : AC(8)

Diseases : Aging : CK(1351) : AC(369)

Pharmacological Actions : Telomerase Upregulation : CK(81) : AC(25)

Various plant substances inhibit chemically-induced mammary gland tumor promotion.

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Pubmed Data : Nutr Cancer. 2008 Mar-Apr;60(2):227-34. PMID: 1905902

Article Published Date : Mar 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Beta Sitosterol : CK(43) : AC(14), Curcumin : CK(2910) : AC(1482), D-Limonene : CK(20) : AC(8), DHEA (Dehydroepiandrosterone) : CK(230) : AC(37), Silymarin : CK(36) : AC(8)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Chemopreventive : CK(1528) : AC(382)

Related Blogs

Is Milk Thistle Useful for Viral Hepatitis?

Written by Case Adams, Naturopath

Milk thistle has been successfully used to treat liver inflammation for centuries. Over recent years, doctors have been applying it to hepatitis conditions with varying success. Now recent research is confirming that Milk thistle's primary constituent complex, Silymarin, may indeed be helpful for liver inflammation, but its ability to treat viral hepatitis is being questioned.

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