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Article Count - 56
Cumulative Knowledge - 331

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Quick Summary: Current access displays 2 out of 62 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Endothelial Dysfunction	42	4	Log in \| Sign up
C-Reactive Protein	40	4	Log in \| Sign up

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View the Evidence: Substances

Exposure to isoflavone-containing soy products may improve endothelial function.

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2010 Aug 14. Epub 2010 Aug 14. PMID: 20709515

Article Published Date : Aug 14, 2010

Study Type : Meta Analysis

Additional Links

Substances : Isoflavones : CK(627) : AC(124), phytoestrogens : CK(699) : AC(210), Soy : CK(1672) : AC(347), Soy Protein : CK(2307) : AC(56)

Diseases : Cardiac Mortality : CK(703) : AC(67), Coronary Artery Disease : CK(1305) : AC(136), Endothelial Dysfunction : CK(897) : AC(173)

Safety Study: There is little evidence that in those with normal thyroid function soy has any adverse effects. In those with hypothyroidism adequate iodine should be consumed to counterbalance the soy consumption.

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Pubmed Data : Thyroid. 2006 Mar;16(3):249-58. PMID: 16571087

Article Published Date : Mar 01, 2006

Study Type : Meta Analysis

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy : CK(1672) : AC(347), Soy Protein : CK(2307) : AC(56)

Diseases : Hypothyroidism : CK(537) : AC(78)

A daily supplement of soy protein prevents the increase in subcutaneous and total abdominal fat in postmenopausal women.

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Pubmed Data : Fertil Steril. 2007 Dec;88(6):1609-17. Epub 2007 Apr 6. PMID: 17412329

Article Published Date : Dec 01, 2007

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Abdominal Obesity (Midsection Fat) : CK(348) : AC(53)

A diet high in plant sterols, soy protein, viscous fibers and almonds compares favorably to statin therapy in reducing C-reactive protein.

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2005 Jul;59(7):851-60. PMID: 15900306

Article Published Date : Jul 01, 2005

Study Type : Human Study

Additional Links

Substances : Almond : CK(107) : AC(15), Fiber : CK(484) : AC(70), Plant Sterols/Stanols : CK(32) : AC(5), Soy Protein : CK(2307) : AC(56)

Diseases : C-Reactive Protein : CK(819) : AC(74), Cardiovascular Diseases : CK(5138) : AC(641), Hyperlipidemia : CK(1211) : AC(109), Inflammation : CK(1077) : AC(363)

Additional Keywords : Therapeutic Action not Inferior to Drug Therapy : CK(51) : AC(6)

A high intake of soy and isoflavones may be associated with a reduced prevalence of allergic rhinitis.

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Pubmed Data : J Allergy Clin Immunol. 2005 Jun;115(6):1176-83. PMID: 15940131

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Allergic Rhinitis : CK(318) : AC(40)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

A low glycemic index diet with soy protein and phytosterols improves risk factors for cardiovascular disease in postmenopausal women.

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Pubmed Data : Nutrition. 2006 Feb;22(2):104-13. PMID: 16459222

Article Published Date : Feb 01, 2006

Study Type : Human Study

Additional Links

Substances : Phytosterols : CK(63) : AC(8), Soy Protein : CK(2307) : AC(56)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Postmenopausal Disorders : CK(285) : AC(35)

Therapeutic Actions : Dietary Modification: Low Glycemic Diet : CK(60) : AC(6)

A soy rich diet may prevent the vaginal atrophy in postmenopause.

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Pubmed Data : Vascul Pharmacol. 2008 Jan;48(1):14-20. Epub 2007 Nov 13. PMID: 12927310

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Estrogen Deficiency : CK(57) : AC(19), Postmenopausal Disorders : CK(285) : AC(35), Vaginal Atrophy : CK(10) : AC(1), Vaginal Diseases : CK(20) : AC(2)

Mycoprotein and tofu have satiating properties that persist for several hours after a meal.

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Pubmed Data : Appetite. 2006 Jan;46(1):41-8. Epub 2005 Dec 20. PMID: 16364496

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Mushrooms: All : CK(578) : AC(230), Soy Protein : CK(2307) : AC(56)

Diseases : Weight Probems: Appetite : CK(122) : AC(16)

Additional Keywords : Fungal Proteins : CK(16) : AC(6)

Regular soy food intake may be associated with a reduced risk of breast cancer, and this effect is more pronounced in premenopausal women.

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2008;60(5):568-76. PMID: 18791919

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Soy : CK(1672) : AC(347), Soy Protein : CK(2307) : AC(56)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Soy and isoflavone intake may decrease the likelihood of periodontal disease.

Click here to read the entire abstract

Pubmed Data : BMC Public Health. 2008;8:39. Epub 2008 Jan 29. PMID: 18226266

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Periodontal Diseases : CK(134) : AC(34)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Soy and whey protein supplements may increase exercise intensity in athletes.

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Pubmed Data : Eur J Nutr. 2006 Aug;45(5):259-66. Epub 2006 Mar 30. PMID: 16575496

Article Published Date : Aug 01, 2006

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56), Whey : CK(323) : AC(72)

Diseases : Athletic Performance : CK(479) : AC(61)

Pharmacological Actions : Ergogenic : CK(43) : AC(6)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Soy consumption reduces the risk of non-small-cell lung cancers with epidermal growth factor receptor mutations among Japanese.

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Pubmed Data : Cancer Sci. 2008 Jun;99(6):1202-8. Epub 2008 Apr 21. PMID: 18429954

Article Published Date : Jun 01, 2008

Study Type : Human Study

Additional Links

Substances : Soy : CK(1672) : AC(347), Soy Protein : CK(2307) : AC(56)

Diseases : Lung Cancer : CK(496) : AC(198), Non-Small-Cell Lung Carcinoma : CK(45) : AC(7)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Soy formula and soy isoflavone consumption is associated with reduced rotavirus infectivity.

Click here to read the entire abstract

Pubmed Data : Nutr Rev. 2009 Nov;67 Suppl 2:S192-200. PMID: 19906223

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Infant Infections : CK(420) : AC(45), Rotavirus Infections : CK(75) : AC(16)

Pharmacological Actions : Antiviral Agents : CK(613) : AC(280)

Soy inclusion in the diet can modify the risk factors of heart disease and improve kidney function in patients with type 2 diabetes with nephropathy.

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2003 Oct;57(10):1292-4. PMID: 14506491

Article Published Date : Oct 01, 2003

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : Diabetes: Cardiovascular Illness : CK(666) : AC(104), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Hyperlipidemia : CK(1211) : AC(109), Proteinuria : CK(103) : AC(20)

Pharmacological Actions : Hypolipidemic : CK(370) : AC(80)

Soy phytoestrogen has a positive effect on bone turnover indicators in menopausal women with osteopenia.

Click here to read the entire abstract

Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 16255781

Article Published Date : Dec 01, 1999

Study Type : Human Study

Additional Links

Substances : phytoestrogens : CK(699) : AC(210), Soy Protein : CK(2307) : AC(56)

Diseases : Osteopenia : CK(207) : AC(41), Osteoporosis : CK(1171) : AC(205), Postmenopausal Disorders : CK(285) : AC(35)

Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation : CK(66) : AC(16)

Soy protein consumption significantly affected cardiovascular risk factors and kidney-related biomarkers among type 2 diabetic patients with nephropathy.

Click here to read the entire abstract

Pubmed Data : Diabetes Res. 1984 Nov;1(4):201-7. PMID: 18184902

Article Published Date : Nov 01, 1984

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : C-Reactive Protein : CK(819) : AC(74), Diabetes: Cardiovascular Illness : CK(666) : AC(104), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Proteinuria : CK(103) : AC(20)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433)

Soy protein diet improves endothelial dysfunction in renal transplant patients.

Click here to read the entire abstract

Pubmed Data : Nephrol Dial Transplant. 2007 Jan;22(1):229-34. Epub 2006 Sep 23. PMID: 16998212

Article Published Date : Jan 01, 2007

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : C-Reactive Protein : CK(819) : AC(74), Endothelial Dysfunction : CK(897) : AC(173), Kidney Transplant : CK(65) : AC(8), Organ Transplantation: Kidney : CK(80) : AC(8)

Soy protein may prevent prostate cancer development.

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2008;60(1):7-13. PMID: 18444130

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Prostate Cancer : CK(998) : AC(288)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Soy protein reduces cholesterol oxidation in patients on hemodialysis.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2006;9(3):368-72. PMID: 17004900

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Daidzein : CK(965) : AC(28), Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Cholesterol: Oxidation : CK(457) : AC(98), Hemodialysis : CK(393) : AC(38)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women.

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2003 Jul;78(1):123-30. PMID: 12816781

Article Published Date : Jul 01, 2003

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : Endothelial Dysfunction : CK(897) : AC(173), Postmenopausal Disorders : CK(285) : AC(35)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Soy proteins given as part of the daily protein intake have beneficial effects on serum LDL cholesterol levels of renal transplant recipients with moderate hypercholesterolemia.

Click here to read the entire abstract

Pubmed Data : J Ren Nutr. 2004 Jan;14(1):31-5. PMID: 14740328

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : High Cholesterol : CK(1718) : AC(198), Kidney Transplant : CK(65) : AC(8)

Soy supplementation reduced total and subcutaneous abdominal fat in postmenopausal women.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2006 Spring;9(1):84-9. PMID: 20435291

Article Published Date : Mar 01, 2006

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : Obesity : CK(1849) : AC(275), Overweight : CK(2176) : AC(342)

Pharmacological Actions : Interleukin-6 Downregulation : CK(470) : AC(135), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Soy-protein consumption reduces proteinuria in type 2 diabetes with nephropathy.

Click here to read the entire abstract

Pubmed Data : CNS Spectr. 1999 Dec;4(12):34-47. PMID: 19758824

Article Published Date : Dec 01, 1999

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Proteinuria : CK(103) : AC(20)

Soybean protein supplementation results in a reduction in systolic and diastolic blood pressure.

Click here to read the entire abstract

Pubmed Data : Ann Intern Med. 2005 Jul 5;143(1):1-9. PMID: 15998749

Article Published Date : Jul 05, 2005

Study Type : Human Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Hypotensive : CK(383) : AC(53)

The hypotensive and anti-inflammatory effect of soy nut consumption may be due to a reduction in solube vascular cell adhesion molecule-1 which results in an improvement in endothelial function.

Click here to read the entire abstract

Pubmed Data : Am J Cardiol. 2008 Jul 1;102(1):84-6. Epub 2008 Apr 16. PMID: 18572041

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)

Diseases : C-Reactive Protein : CK(819) : AC(74), Hypertension : CK(2783) : AC(271), Inflammation : CK(1077) : AC(363)

Pharmacological Actions : Interleukin-6 Downregulation : CK(470) : AC(135), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71), Vascular Cell Adhesion Molecule-1 Inhibitor : CK(94) : AC(24)

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