focusYou term Breast Cancer has been focused. All 33 articles with this term will be displayed first for quicker access down below.

Soy

Soy

Wikipedia Image

Member Page View Enabled

You are currently viewing this page as a full fledged member! If you would like all pages to display this detail of information and wish to sign up for a membership, please click here

User Options

Download a PDF Document of this page with up to the first 50 articlesPurchase the Exhaustive Downloadable Document on this TopicMake a Request for GMI to add more Articles on this Topic Immediately (Purchase Required)View a Printer Friendly version of this pageE-mail this page to a friendPerform a Search with this Topic
Hover over an icon for more information

Additional Topics Details for this Page

View the Evidence: Substances

A high intake of some fruits, vegetables, and soybeans may be associated with a reduced breast cancer risk.

Pubmed Data : Int J Vitam Nutr Res. 2007 Mar;77(2):130-41. PMID: 17896586
Article Published Date : Mar 01, 2007
Study Type : Human Study
Additional Links
Substances : Fruit: All : CK(1836) : AC(472), Soy : CK(1672) : AC(347), Vegetables: All : CK(551) : AC(69)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and recurrence.

Pubmed Data : JAMA. 2009 Dec 9;302(22):2437-43. PMID: 19996398
Article Published Date : Dec 09, 2009
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

An increased intake of some fruits, vegetables, and soy foods may be associated with breast cancer risk reduction in Korean women.

Pubmed Data : Nutr Cancer. 2007;57(1):20-7. PMID: 17516859
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Fruit: All : CK(1836) : AC(472), Soy : CK(1672) : AC(347), Vegetables: All : CK(551) : AC(69)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Frequent miso soup and isoflavone consumption is associated with a reduced risk of breast cancer in Japanese women.

Pubmed Data : J Natl Cancer Inst. 2003 Jun 18;95(12):906-13. PMID: 12813174
Article Published Date : Jun 18, 2003
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages : CK(670) : AC(133), Isoflavones : CK(627) : AC(124), Miso : CK(307) : AC(4), Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

High dietary intake of soy isoflavones was associated with lower risk of recurrence among post-menopausal patients with breast cancer positive for estrogen and progesterone receptor and those who were receiving anastrozole (Arimidex) as endocrine therapy.

Pubmed Data : J Med Food. 2010 Feb;13(1):179-88. PMID: 20956506
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Substances : Isoflavones : CK(627) : AC(124), Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Additional Keywords : Drug: Anastrozole : CK(10) : AC(1), Drug Synergy : CK(327) : AC(147)

Mortality from Lung Cancer, Breast Cancer and Ischemic Heart Disease is inversely associated with soy consumption.

Pubmed Data : Prev Med. 2006 Jul;43(1):20-6. Epub 2006 May 2. PMID: 16631248
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621), Ischemic Heart Disease : CK(23) : AC(5), Lung Cancer : CK(496) : AC(198)
Additional Keywords : Inverse Relationship : CK(40) : AC(4), Risk Reduction : CK(1909) : AC(196)

Regular soy food intake may be associated with a reduced risk of breast cancer, and this effect is more pronounced in premenopausal women.

Pubmed Data : Nutr Cancer. 2008;60(5):568-76. PMID: 18791919
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347), Soy Protein : CK(2307) : AC(56)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Soy food consumption reduces the risk of death in breast cancer survivors.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2011 Feb 25. Epub 2011 Feb 25. PMID: 21357380
Article Published Date : Feb 25, 2011
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Soy food intake has a protective role against premenopausal breast cancer.

Pubmed Data : Am J Clin Nutr. 2009 Jun;89(6):1920-6. Epub 2009 Apr 29. PMID: 19403632
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Isoflavones : CK(627) : AC(124), Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Various doses of soy isoflavones do not act like hormone replacement medication on breast density.

Pubmed Data : J Nutr. 2009 May;139(5):981-6. Epub 2009 Mar 25. PMID: 19321587
Article Published Date : May 01, 2009
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)

A diet containing an isoflavone-poor soy protein concentrate may inhibit breast tumor progression and metastasis development.

Pubmed Data : Mol Nutr Food Res. 2008 Oct;52(10):1121-9. PMID: 18655005
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)
Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Metastatic : CK(82) : AC(33)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)

Enterolactone and enterodiol have been shown to negate the tumor-stimulating effect of genistein in a mouse model of breast cancer.

Pubmed Data : Mol Nutr Food Res. 2007 Jul;51(7):845-56. PMID: 17579892
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Enterodiol : CK(34) : AC(12), Enterolactone : CK(301) : AC(10), Flaxseed : CK(275) : AC(57), Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124), Lignans : CK(110) : AC(31), phytoestrogens : CK(699) : AC(210), Soy Protein : CK(2307) : AC(56)
Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Prevention : CK(525) : AC(73)
Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1052) : AC(775)

Soy and tea bioactive components may be used to inhibit the progression of estrogen-dependent breast cancer.

Pubmed Data : Int J Cancer. 2004 Jan 1;108(1):8-14. PMID: 14618609
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(158) : AC(40), Isoflavones : CK(627) : AC(124), Soy Protein : CK(2307) : AC(56)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114)
Additional Keywords : Drug Synergy : CK(327) : AC(147), Natural Substance Synergy : CK(144) : AC(81), Plant Extracts : CK(3572) : AC(1216)

Soy and whey protein may reduce the susceptibility of mammary tissue to carcinogenic chemicals.

Pubmed Data : Toxicol Sci. 2002 Nov;70(1):40-5. PMID: 12388833
Article Published Date : Nov 01, 2002
Study Type : Animal Study
Additional Links
Substances : Soy Protein : CK(2307) : AC(56), Whey : CK(323) : AC(72)
Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Prevention : CK(525) : AC(73)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)

Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice.

Pubmed Data : Carcinogenesis. 2007 Jun;28(6):1217-23. Epub 2007 Jan 18. PMID: 17234721
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : Genistein : CK(450) : AC(174), Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Chemosensitizer : CK(197) : AC(159)
Additional Keywords : Drug: Tamoxifen : CK(380) : AC(57), Drug Synergy : CK(327) : AC(147)

Soy phytoestrogen exhibit antitumor and anti-angiogenic activity in chemically induced mammary tumors in ovariectomized rats.

Pubmed Data : J Food Sci. 2009 Sep;74(7):H237-42. PMID: 19895476
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124), phytoestrogens : CK(699) : AC(210)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Soy protein may protect against the development of a more aggressive breast carcinoma.

Pubmed Data : Mol Cell Biochem. 2006 Oct;290(1-2):169-76. Epub 2006 Jun 20. PMID: 16941229
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Substances : Soy Protein : CK(2307) : AC(56)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Soy, and especially whey protein protects against chemically-induced mammary cancer in rats.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2000 Jan;9(1):113-7. PMID: 10667471
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Substances : Soy Protein : CK(2307) : AC(56), Whey : CK(323) : AC(72)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Chemopreventive : CK(1528) : AC(382)

The soybean peptide lunasin suppresses chemically-induced mammary tumors.

Pubmed Data : Cancer Prev Res (Phila). 2010 Dec;3(12):1586-95. Epub 2010 Sep 17. PMID: 21535606
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Substances : Lunasin : CK(2) : AC(1), Soy : CK(1672) : AC(347)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides.

Pubmed Data : Biochem Biophys Res Commun. 1997 Apr 28;233(3):692-6. PMID: 9168916
Article Published Date : Apr 28, 1997
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124)
Diseases : Breast Cancer : CK(2354) : AC(621), Pesticide Toxicity : CK(147) : AC(45)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)
Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Genistein acts as a chemosensitzer, contributing to overcoming drug-resistance in prostate, breast, lung and pancreatic ancers.

Pubmed Data : Cancer Res. 2005 Aug 1;65(15):6934-42. PMID: 16061678
Article Published Date : Aug 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(450) : AC(174)
Diseases : Breast Cancer : CK(2354) : AC(621), Cancers: Drug Resistant : CK(225) : AC(147), Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66), Lung Cancer : CK(496) : AC(198), Pancreatic Cancer : CK(530) : AC(168), Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), NF-kappaB Inhibitor : CK(595) : AC(401)
Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Related Blogs

This Humble Food Extract Puts Bone Drugs To Shame
Written by Sayer Ji, Founder
According to research published in the British Journal of Pharmacology in 2008 alendronate (Fosamax), raloxifene (Evista) and estradiol (bioidentical estrogen) are inferior to the phytoestrogen genistein commonly found in fermented soy*, red clover, kudzu, fava beans and coffee in preserving bone mineral density (quantity) and strength (quality) in an animal model of menopausal (ovariectomy-induced) osteoporosis.

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.