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Article Count - 234
Cumulative Knowledge - 1033

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View the Evidence: Substances

Green tea (-)-epigallocatechin-3-gallate reduces body weight with regulation of multiple genes expression in adipose tissue of diet-induced obese mice.

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Pubmed Data : Ann Nutr Metab. 2009;54(2):151-7. Epub 2009 Apr 22. PMID: 19390166

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Green Tea : CK(930) : AC(294)

Diseases : Obesity : CK(1869) : AC(275), Overweight : CK(2176) : AC(342)

Pharmacological Actions : Anti-Adipogenic : CK(91) : AC(44)

Additional Keywords : Anti-Obesity Agents : CK(96) : AC(26)

Green tea (EGCG), black tea and coffee may protect against Bordetella pertussis infection.

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Pubmed Data : Chem Biol Interact. 2006 Dec 1;164(1-2):102-14. Epub 2006 Sep 16. PMID: 1402092

Article Published Date : Dec 01, 2006

Study Type : Animal Study

Additional Links

Substances : Black Tea : CK(158) : AC(40), Catechin : CK(403) : AC(130), Coffee : CK(412) : AC(58), Green Tea : CK(930) : AC(294)

Diseases : Pertussis : CK(142) : AC(14), Whooping Cough : CK(66) : AC(7)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Green tea ameliorates renal oxidative damage induced by gentamicin in rats.

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Pubmed Data : Aging Clin Exp Res. 2005 Oct;17(5):385-9. PMID: 20067862

Article Published Date : Oct 01, 2005

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Chemotherapy-Induced Toxicity: Gentamicin : CK(22) : AC(10), Chemotherapy-Induced Toxicity: Kidney : CK(8) : AC(4), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival.

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Pubmed Data : Free Radic Biol Med. 2010 Mar 15;48(6):831-838. Epub 2010 Jan 11. PMID: 20064606

Article Published Date : Mar 15, 2010

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Aging : CK(1351) : AC(369)

Green tea catechin prevents copper gluconate toxicity.

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Pubmed Data : Food Chem Toxicol. 2008 May;46(5):1760-70. Epub 2008 Jan 21. PMID: 18313194

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Green Tea : CK(930) : AC(294)

Diseases : Copper Toxicity : CK(23) : AC(10)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)

Green tea catechin prevents the decline of glutathione peroxidase activity and protein oxidative damage in aging mouse brain.

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Pubmed Data : Biogerontology. 2007 Aug;8(4):423-30. Epub 2007 Feb 20. PMID: 17310319

Article Published Date : Aug 01, 2007

Study Type : Animal Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Green Tea : CK(930) : AC(294)

Diseases : Aging : CK(1351) : AC(369), Aging: Brain : CK(1747) : AC(68), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Glutathione Upregulation : CK(144) : AC(48), Neuroprotective Agents : CK(962) : AC(480)

Green tea catechins and black tea theaflavins inhibit SV40-associated mammary cancer in a rodent experimental model.

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Pubmed Data : J Agric Food Chem. 2007 May 2;55(9):3378-85. Epub 2007 Apr 4. PMID: 17407311

Article Published Date : May 02, 2007

Study Type : Animal Study

Additional Links

Substances : Black Tea : CK(158) : AC(40), Catechin : CK(403) : AC(130), Green Tea : CK(930) : AC(294)

Diseases : Breast Cancer : CK(2361) : AC(621), Simian virus 40 (SV40) : CK(7) : AC(5)

Pharmacological Actions : Apoptotic : CK(1535) : AC(1155), Chemopreventive : CK(1528) : AC(382)

Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer.

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Pubmed Data : Int J Oncol. 2010 Jul ;37(1):111-23. PMID: 20514403

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Tea : CK(989) : AC(234)

Diseases : Cancers: Drug Resistant : CK(225) : AC(147), Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Chemosensitizer : CK(197) : AC(159)

Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55), Drug Synergy : CK(327) : AC(147)

Green tea catechins have a suppressive effect on morphologic and functional regression of the brain in aged mice with accelerated senescence .

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Pubmed Data : Exp Gerontol. 2004 Jul;39(7):1027-34. PMID: 15236762

Article Published Date : Jul 01, 2004

Study Type : Animal Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Tea : CK(989) : AC(234)

Diseases : Aging : CK(1351) : AC(369), Aging: Brain : CK(1747) : AC(68), DNA damage : CK(711) : AC(293), Learning disorders : CK(154) : AC(36), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Green tea decreases iron in plasma, eliminates lipid peroxidation in plasma and destroys formation of red blood cell reactive oxygen species.

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Pubmed Data : Med Chem. 2008 Jul;4(4):365-70. PMID: 18673149

Article Published Date : Jul 01, 2008

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Iron Overload : CK(59) : AC(13), Thalassemia : CK(118) : AC(13)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Green tea exhibits cardioprotective properties against myocardial ischemia.

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Pubmed Data : Nutr Res. 2010 Jan;30(1):32-9. PMID: 20116658

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Tea : CK(989) : AC(234)

Diseases : Myocardial Ischemia : CK(87) : AC(37)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196), Phase II Detoxification Enzyme Inducer : CK(64) : AC(32)

Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Green tea extract in combination with cyclosporine A (CyA) significantly prolongs graft survival and reduces (CyA) induced nephrotoxicity.

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Pubmed Data : J Surg Res. 2009 Jun 1;154(1):85-90. Epub 2008 Jun 2. PMID: 19201423

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Organ Transplantation : CK(50) : AC(17)

Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice.

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Pubmed Data : Am J Obstet Gynecol. 2010 Jan 12. Epub 2010 Jan 12. PMID: 20074693

Article Published Date : Jan 12, 2010

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate) : CK(859) : AC(109), Green Tea : CK(930) : AC(294)

Diseases : Leiomyoma : CK(37) : AC(16)

Pharmacological Actions : Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155)

Green tea extract may mprove muscle health by reducing or delaying necrosis in an animal model of muscular dystrophy.

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Pubmed Data : Am J Clin Nutr. 2002 Apr;75(4):749-53. PMID: 11916763

Article Published Date : Apr 01, 2002

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Duchenne's Muscular Dystrophy : CK(12) : AC(6), Muscular Dystrophies : CK(26) : AC(9)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Green tea extract suppresses the oxidative stress and endothelin-1 expression associated with pulmonary fibrosis.

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Pubmed Data : Lung. 2006 Sep-Oct;184(5):287-95. PMID: 17235729

Article Published Date : Sep 01, 2006

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Interstitial Lung Diseases : CK(70) : AC(12)

Pharmacological Actions : Endothelin-1 Inhibitor : CK(2) : AC(1)

Green tea has a beneficial effect in a rat model of non-alcoholic fatty liver.

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Pubmed Data : J Clin Biochem Nutr. 2009 May;44(3):239-46. Epub 2009 Apr 25. PMID: 19430612

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Fatty Liver : CK(493) : AC(122)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Green tea has a growth inhibitory and antimetastatic effect on metastasis-specific mouse mammary cancer.

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Pubmed Data : Clin Cancer Res. 2005 Mar 1;11(5):1918-27. PMID: 15756018

Article Published Date : Mar 01, 2005

Study Type : Animal Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174)

Diseases : Breast Cancer: Lung Metastasis : CK(13) : AC(7), Breast Cancer: Metastatic : CK(82) : AC(33)

Pharmacological Actions : Anti-metastatic : CK(192) : AC(115), Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155)

Green tea has a protective effect against carcinogenesis induced by asbestos plus benzo(a)pyrene in rat.

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Pubmed Data : Biomed Environ Sci. 1995 Mar;8(1):54-8. PMID: 7605600

Article Published Date : Mar 01, 1995

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Asbestos Toxicity : CK(4) : AC(3), Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), Lung Cancer : CK(496) : AC(198)

Green tea has a protective effect on aging rats.

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Pubmed Data : J Pharm Biomed Anal. 2011 Mar 26. Epub 2011 Mar 26. PMID: 21444175

Article Published Date : Mar 26, 2011

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Aging : CK(1351) : AC(369)

Additional Keywords : Metabolome : CK(2) : AC(1)

Green tea has antifibrotic activity in in vitro and in vivo models of liver fibrosis.

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Pubmed Data : World J Gastroenterol. 2009 Nov 7;15(41):5200-5. PMID: 19891020

Article Published Date : Nov 07, 2009

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Liver Fibrosis : CK(341) : AC(74)

Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Green tea has radioprotective properties against gamma-radiation exposure in mice.

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Pubmed Data : Phytother Res. 2008 Oct;22(10):1380-3. PMID: 18570224

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174), Tea : CK(989) : AC(234)

Diseases : Radiation Induced Illness : CK(1018) : AC(249)

Pharmacological Actions : Radioprotective : CK(458) : AC(183)

Green tea inhibits gluconeogenesis in rats.

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Pubmed Data : Biomed Res.2009 Feb;30(1):25-9. PMID: 19265260

Article Published Date : Feb 01, 2009

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218), Diabetes Mellitus: Type 2 : CK(3429) : AC(341)

Pharmacological Actions : Gluconeogenesis Inhibitor : CK(20) : AC(14)

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