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Additional Topics Details for this Page
Article Count
- 16
Cumulative Knowledge
- 22
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Quick Summary: Current access displays 2 out of 21 associated Diseases
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View the Evidence: Substances
A tocotrienol rich fraction of palm oil protects against chemically-induced kidney damage.
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Jul 30;186(2):228-38. Epub 2010 Apr 28. PMID:
20433818
Article Published Date
: Jul 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Palm Oil : CK(30) : AC(16)
,
Tocotrienols : CK(22) : AC(16)
Diseases
:
Kidney Damage : CK(120) : AC(42)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Renoprotective : CK(191) : AC(90)
Mixed tocotrienols inhibit prostate carcinogenesis in mice.
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2010 Aug;62(6):789-94. PMID:
20661828
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
Diseases
:
Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions
:
Anticarcinogenic Agents : CK(521) : AC(275)
,
Apoptotic : CK(1535) : AC(1155)
,
Cell cycle arrest : CK(390) : AC(319)
Tocotrienol offers protection against free radical-induced damage of rat bone.
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2005 Sep;32(9):761-70. PMID:
16173934
Article Published Date
: Sep 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
,
Vitamin E : CK(1285) : AC(221)
Diseases
:
Osteoporosis : CK(1171) : AC(205)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Interleukin-6 Downregulation : CK(470) : AC(135)
Tocotrienol rich fractions of palm oil and rice bran oil protect against kidney damage associated with high blood sugar in type 1 diabetes.
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Dec 5;188(3):651-8. Epub 2010 Sep 28. PMID:
20816776
Article Published Date
: Dec 05, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Palm Oil : CK(30) : AC(16)
,
Rice Bran : CK(29) : AC(14)
,
Tocotrienols : CK(22) : AC(16)
Diseases
:
Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Hypoglycemic Agents : CK(563) : AC(156)
,
Renoprotective : CK(191) : AC(90)
Tocotrienol-rich fraction and tocopherol prevent aspirin-induced gastric lesions.
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2002;11(4):309-13. PMID:
12495264
Article Published Date
: Jan 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
,
Vitamin E : CK(1285) : AC(221)
Diseases
:
Aspirin-Induced Toxicity : CK(83) : AC(24)
,
Gastric Ulcer : CK(246) : AC(91)
,
Lipid Peroxidation : CK(403) : AC(127)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Gastroprotective : CK(62) : AC(31)
,
Malondialdehyde Down-regulation : CK(76) : AC(21)
Tocotrienols are more effective than d-alpha tocopherol in protecting the bone from free radical damage.
Click here to read the entire abstract
Pubmed Data
: N Engl J Med. 2005 Mar 31;352(13):1293-304. Epub 2005 Mar 7. PMID:
18598299
Article Published Date
: Mar 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Palm Tree : CK(8) : AC(4)
,
Tocotrienols : CK(22) : AC(16)
Diseases
:
Bone Diseases : CK(15) : AC(4)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
Tocotrienols inhibit hepatocarcinogenesis induced by 2-acetylaminofluorene in rats.
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 1991 Apr ;53(4 Suppl):1076S-1081S. PMID:
1672785
Article Published Date
: Apr 01, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
Diseases
:
Liver Cancer : CK(1641) : AC(266)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Chemopreventive : CK(1528) : AC(382)
A tocotrienol-rich fraction from rice bran enhances cisplatin-induced cytotoxicity in human mesothelioma cells.
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2010 Feb 1. Epub 2010 Feb 1. PMID:
20127663
Article Published Date
: Feb 01, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Rice Bran : CK(29) : AC(14)
,
Tocotrienols : CK(22) : AC(16)
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66)
,
Mesothelioma : CK(30) : AC(10)
Pharmacological Actions
:
Chemosensitizer : CK(197) : AC(159)
Additional Keywords
:
Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)
Gamma Tocotrienol (vitamin E fraction) induces cell death in human gastric cancer cells.
Click here to read the entire abstract
Pubmed Data
: Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1164-71. Epub 2009 May 28. PMID:
18602811
Article Published Date
: Aug 01, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
Diseases
:
Human Gastric Adenocarcinoma : CK(3) : AC(3)
Gamma- and delta-tocotrienol down-regulate cholesterol production.
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2006 Sep 1;281(35):25054-61. Epub 2006 Jul 10. PMID:
16831864
Article Published Date
: Sep 01, 2006
Study Type
: In Vitro Study
Additional Links
Substances
:
Tocotrienol: Delta : CK(7) : AC(7)
,
Tocotrienols : CK(22) : AC(16)
,
Vitamin E : CK(1285) : AC(221)
Diseases
:
High Cholesterol : CK(1718) : AC(198)
Gamma-tocotrienol has broad therapeutic activity against human melanoma cells.
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2009;61(3):357-66. PMID:
19373609
Article Published Date
: Jan 01, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Tocotrienol: Gamma : CK(12) : AC(12)
,
Tocotrienols : CK(22) : AC(16)
,
Vitamin E: Gamma-tocotrienol : CK(43) : AC(12)
Diseases
:
Malignant Melanoma : CK(189) : AC(8)
,
Melanoma : CK(171) : AC(87)
,
Melanoma: Metastatic : CK(21) : AC(13)
Additional Keywords
:
Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)
Palm tocotrienols inhibit proliferation of mouse mammary cancer cells.
Click here to read the entire abstract
Pubmed Data
: J Interferon Cytokine Res. 2010 Dec;30(12):909-16. PMID:
21121862
Article Published Date
: Dec 01, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Palm Oil : CK(30) : AC(16)
,
Tocotrienol: Alpha : CK(2) : AC(2)
,
Tocotrienol: Delta : CK(7) : AC(7)
,
Tocotrienol: Gamma : CK(12) : AC(12)
,
Tocotrienols : CK(22) : AC(16)
Diseases
:
Breast Cancer : CK(2361) : AC(621)
Tocotrienols have potenti antifibrogenic effects which may help prevent and/or treat bowel stenosis in Crohn's disease patients.
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2010 Aug 3. Epub 2010 Aug 3. PMID:
20684017
Article Published Date
: Aug 03, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
Diseases
:
Bowel Stenosis : CK(1) : AC(1)
,
Crohn's Disease : CK(122) : AC(22)
Tocotrienols induce programmed cell death in breast cancer cell lines.
Click here to read the entire abstract
Pubmed Data
: Breast Cancer Res Treat. 2010 Feb 16. Epub 2010 Feb 16. PMID:
20157774
Article Published Date
: Feb 16, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
Diseases
:
Breast Cancer : CK(2361) : AC(621)
Pharmacological Actions
:
Apoptotic : CK(1535) : AC(1155)
Tocotrienols inhibit growth and induce programmed cell death in human cervical cancer cells.
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2010 Feb 11. Epub 2010 Feb 11. PMID:
20150225
Article Published Date
: Feb 11, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
Diseases
:
Cervical Cancer : CK(368) : AC(69)
Pharmacological Actions
:
Antiproliferative : CK(1058) : AC(775)
,
Apoptotic : CK(1535) : AC(1155)
,
Interleukin-6 upregulation : CK(26) : AC(7)
Tocotrienols induce cell death in human breast cancer cells.
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1999;33(1):26-32. PMID:
10227040
Article Published Date
: Jan 01, 1999
Additional Links
Substances
:
Tocotrienols : CK(22) : AC(16)
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