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Vitamin B-12

Vitamin B-12

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Article Count - 94
Cumulative Knowledge - 702

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Quick Summary: Current access displays 2 out of 130 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Vitamin B 12 Deficiency	188	23	Log in \| Sign up
High Homocysteine	102	12	Log in \| Sign up

Quick Summary: Current access displays 2 out of 13 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Antioxidants	30	3	Log in \| Sign up
Anticonvulsants	20	2	Log in \| Sign up

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View the Evidence: Substances

Lower vitamin B12 levels are associated with increased rates of double incontinence.

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Pubmed Data : J Gerontol A Biol Sci Med Sci. 2002 Sep;57(9):M583-7. PMID: 12196495

Article Published Date : Sep 01, 2002

Study Type : Meta Analysis

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Incontinence: Double : CK(20) : AC(1), Vitamin B 12 Deficiency : CK(220) : AC(34)

5-methyltehydrofolate (folic acid) and vitamin B12 ameliorate red blood cell abnormalities in pediatric patients with Cystic Fibrosis.

Click here to read the entire abstract

Pubmed Data : PLoS One. 2009;4(3):e4782. Epub 2009 Mar 11. PMID: 19277125

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(542) : AC(77), Vitamin B-12 : CK(752) : AC(94)

Diseases : Cystic Fibrosis : CK(703) : AC(77)

A B12 cream containing avocado oil has potential for the treatment of psoriasis,

Click here to read the entire abstract

Pubmed Data : Dermatology. 2001;203(2):141-7. PMID: 11586013

Article Published Date : Jan 01, 2001

Study Type : Human Study

Additional Links

Substances : Avocado : CK(47) : AC(17), Vitamin B-12 : CK(752) : AC(94)

Diseases : Psoriasis : CK(270) : AC(42)

A blue-green algae product improves vitamin B12 status and reduces homocysteine.

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2005 Oct;82(4):887-93. PMID: 20108213

Article Published Date : Oct 01, 2005

Study Type : Human Study

Additional Links

Substances : Blue-Green Algae : CK(21) : AC(5), Vitamin B-12 : CK(752) : AC(94)

Diseases : Homocysteine: Elevated : CK(368) : AC(57), Vitamin B 12 Deficiency : CK(220) : AC(34)

Therapeutic Actions : Dietary Modification: Vegetarian : CK(116) : AC(15)

A dietary supplement containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD.

Click here to read the entire abstract

Pubmed Data : J Pineal Res. 2006 Oct;41(3):195-200. PMID: 16948779

Article Published Date : Oct 01, 2006

Study Type : Human Study

Additional Links

Substances : Betaine : CK(16) : AC(4), Folic Acid : CK(542) : AC(77), Melatonin : CK(470) : AC(131), Methionine : CK(52) : AC(12), Tryptophan : CK(322) : AC(30), Vitamin B-12 : CK(752) : AC(94), Vitamin B-6 : CK(412) : AC(48)

Diseases : Gastroesophageal Reflux : CK(278) : AC(41)

Pharmacological Actions : Proton Pump Inhibitor : CK(36) : AC(13)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

A multi-vitamin/nutrient formula has therapeutic value in moderate-stage to later-stage Alzheimer's diease.

Click here to read the entire abstract

Pubmed Data : Am J Alzheimers Dis Other Demen. 2009 Feb-Mar;24(1):27-33. Epub 2008 Dec 3. PMID: 19056706

Article Published Date : Feb 01, 2009

Study Type : Human Study

Additional Links

Substances : Carnitine, Acetyl-L- : CK(40) : AC(4), Folic Acid : CK(542) : AC(77), NAC (N-acetyl-L-cysteine) : CK(264) : AC(62), SAMe (S-adenosylmethionine) : CK(89) : AC(17), Vitamin B-12 : CK(752) : AC(94), Vitamin E : CK(1285) : AC(221)

Diseases : Alzheimer's Disease : CK(886) : AC(160)

Abnormalities in the immune system in pernicious anemia are restored by vitamin B(12) replacement therapy.

Click here to read the entire abstract

Pubmed Data : Med Princ Pract. 2008;17(2):131-5. Epub 2008 Feb 19. PMID: 18287797

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Anemia: Pernicious : CK(13) : AC(2)

Acupoint injection of Vit B12 has a superior therapeutic effect than the drug Carbamazepine in the treatment of trigeminal neuralgia.

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhen Jiu. 2007 Sep;27(9):668-70. PMID: 17926620

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Trigeminal Neuralgia : CK(140) : AC(18)

Therapeutic Actions : Acupoint Injection : CK(20) : AC(2)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis.

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Pubmed Data : Breast Cancer Res Treat. 2004 Feb;83(3):221-31. PMID: 19573556

Article Published Date : Feb 01, 2004

Study Type : Human Study

Additional Links

Substances : Arginine : CK(970) : AC(169), B-complex : CK(278) : AC(32), Garlic : CK(485) : AC(160), Vitamin B-12 : CK(752) : AC(94)

Diseases : Arterial Calcification : CK(154) : AC(25), Atherosclerosis : CK(523) : AC(77), Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.

Click here to read the entire abstract

Pubmed Data : Int J Geriatr Psychiatry. 2011 Jul 21. Epub 2011 Jul 21. PMID: 21780182

Article Published Date : Jul 21, 2011

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(542) : AC(77), Vitamin B-12 : CK(752) : AC(94), Vitamin B-6 : CK(412) : AC(48)

Diseases : Alzheimer's Disease : CK(886) : AC(160), Cognitive Decline/Dysfunction : CK(522) : AC(87), High Homocysteine : CK(368) : AC(57), Neurodegenerative Diseases : CK(1743) : AC(420)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Chronic idiopathic urticaria is associated with low levels of vitamin B12 and concomitant autoimmunity.

Click here to read the entire abstract

Pubmed Data : J Investig Allergol Clin Immunol. 2004;14(4):292-9. PMID: 15736714

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Autoimmune Diseases : CK(5317) : AC(779), Hives : CK(10) : AC(1), Urticaria : CK(130) : AC(8)

Circulating vitamin B12 levels are inversely associated with HPV persistence.

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2002 Apr;11(4):353-9. PMID: 11927495

Article Published Date : Apr 01, 2002

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Cervical Dysplasia : CK(128) : AC(15), Human Papillomavirus (HPV) : CK(153) : AC(22)

Coenzyme-b12 is more effective than cyanocobalamin in normalizing liver enzymes in patients with acute viral hepatitis A.

Click here to read the entire abstract

Pubmed Data : Scand J Infect Dis. 1977;9(2):157-8. PMID: 897571

Article Published Date : Jan 01, 1977

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Hepatitis A : CK(63) : AC(9)

Additional Keywords : Coenzymated Versus Non-Coenzymated Vitamins : CK(10) : AC(1)

Cyanide-containing B12 (Cyanocobalamin) inhibits natural vitamin B12 and causes cytotoxicity.

Click here to read the entire abstract

Pubmed Data : Blood. 1997 Jun 15;89(12):4600-7. PMID: 9192785

Article Published Date : Jun 15, 1997

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Problem Substances : Cyanocobalamin : CK(11) : AC(2)

Cyanocobalamin demonstrates therapeutic activity against aphthous ulcers (canker sores).

Click here to read the entire abstract

Pubmed Data : Am J Med Sci. 2008 Nov;336(5):379-82. PMID: 19011392

Article Published Date : Nov 01, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Aphthous Ulcer : CK(131) : AC(14), Canker Sore : CK(51) : AC(2)

Elevated homocysteine levels associated with polymyalgia rheumatica and giant cell arteritis and the corticosteroid therapy used to treat these conditions may be attenuated with vitamin B12 and folic acid.

Click here to read the entire abstract

Pubmed Data : Rheumatology (Oxford). 2003 Sep;42(9):1055-61. Epub 2003 Apr 16. PMID: 12730520

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(542) : AC(77), Vitamin B-12 : CK(752) : AC(94)

Diseases : Corticosteroid-Induced Toxicity : CK(78) : AC(17), Cortisone Toxicity : CK(26) : AC(7), Giant Cell Arteritis : CK(30) : AC(3), Hyperhomocysteinemia : CK(377) : AC(57), Polymyalgia Rheumatica : CK(63) : AC(7)

Elevated homocysteine levels in the cerebrospinal fluid of patients with fibromyalgia and chronic fatigue syndrome is probably due in part to vitamin b12 deficiency.

Click here to read the entire abstract

Pubmed Data : Scand J Rheumatol. 1997;26(4):301-7. PMID: 9310111

Article Published Date : Jan 01, 1997

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Fibromyalgia : CK(537) : AC(57)

Failure to thrive in infants may be related to to occult maternal pernicious anemia.

Click here to read the entire abstract

Pubmed Data : J Pediatr Hematol Oncol. 2010 May;32(4):319-22. PMID: 20404749

Article Published Date : May 01, 2010

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Infant Care: Failure to Thrive : CK(62) : AC(7), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Vitamin B 12 Deficiency : CK(220) : AC(34)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Folate and vitamin B12 lower homocysteine concentrations in hemodialysis patients.

Click here to read the entire abstract

Pubmed Data : Saudi J Kidney Dis Transpl. 2009 Sep;20(5):779-88. PMID: 19736473

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Hemodialysis : CK(393) : AC(38), High Homocysteine : CK(368) : AC(57)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Folate, riboflavin, thiamin and vitamin b12 protect against premalignant cervical lesions.

Click here to read the entire abstract

Pubmed Data : Cancer Causes Control. 2003 Nov;14(9):859-70. PMID: 14682443

Article Published Date : Nov 01, 2003

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(542) : AC(77), Riboflavin (Vitamin B-2) : CK(77) : AC(13), Thiamine (B-1) : CK(102) : AC(15), Vitamin B-12 : CK(752) : AC(94)

Diseases : Cervical Cancer : CK(368) : AC(69), Cervical Dysplasia : CK(128) : AC(15)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Folic acid and vitamin B(12) supplementation improves vascular endothelial function in patients with coronary heart disease.

Click here to read the entire abstract

Pubmed Data : Circulation. 2000 Nov 14;102(20):2479-83. PMID: 11076820

Article Published Date : Nov 14, 2000

Study Type : Human Study

Additional Links

Substances : Vitamin B-12 : CK(752) : AC(94)

Diseases : Coronary Artery Disease : CK(1305) : AC(136), Endothelial Dysfunction : CK(897) : AC(173)

Pharmacological Actions : Vasodilator Agents : CK(262) : AC(54)

Higher consumption of folate may contribute to the prevention of peripheral arterial disease.

Click here to read the entire abstract

Pubmed Data : J Nutr. 2003 Sep;133(9):2863-7. PMID: 12949378

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(542) : AC(77), Vitamin B-12 : CK(752) : AC(94), Vitamin B-6 : CK(412) : AC(48)

Diseases : Peripheral Arterial Disease : CK(260) : AC(26), Peripheral Vascular Diseases : CK(221) : AC(23)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Higher serum concentrations of folate and vitamin B12 are significantly less likely to be infected with carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs).

Click here to read the entire abstract

Pubmed Data : Int J Women Health. 2010;2:7-12. Epub 2010 Aug 9. PMID: 21072292

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Folate: Dietary : CK(62) : AC(7), Vitamin B-12 : CK(752) : AC(94)

Diseases : Cervical Cancer : CK(368) : AC(69), Human Papillomavirus (HPV) : CK(153) : AC(22)

Homocysteine levels in the tear fluid and plasma of patients with primary open-angle glaucoma is often elevated, indicating that inadequate vitamin b levels (e.g. b6, b12, and folate) may contribute to the disease.

Click here to read the entire abstract

Pubmed Data : Ophthalmic Res. 2008;40(5):249-56. Epub 2008 Apr 25. PMID: 18437035

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(542) : AC(77), Vitamin B-12 : CK(752) : AC(94), Vitamin B-6 : CK(412) : AC(48)

Diseases : Glaucoma : CK(111) : AC(19), High Homocysteine : CK(368) : AC(57)

Homocysteine-lowering therapy may prevent bone loss in Parkinson's disease patients taking levodopa.

Click here to read the entire abstract

Pubmed Data : Mov Disord. 2010 Feb 15;25(3):332-40. PMID: 19938151

Article Published Date : Feb 15, 2010

Study Type : Human Study

Additional Links

Substances : Alpha-Lipoic Acid : CK(384) : AC(82), Vitamin B-12 : CK(752) : AC(94)

Diseases : Homocystinuria : CK(10) : AC(1), Parkinson Disease : CK(543) : AC(79)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

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