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Additional Topics Details for this Page
Article Count
- 48
Cumulative Knowledge
- 382
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Quick Summary: Current access displays 2 out of 63 associated Diseases
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High Homocysteine
61
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Quick Summary: Current access displays 2 out of 3 associated Pharmacological Actions
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View the Evidence: Substances
A dietary supplement containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD.
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2006 Oct;41(3):195-200. PMID:
16948779
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Betaine : CK(16) : AC(4)
,
Folic Acid : CK(542) : AC(77)
,
Melatonin : CK(470) : AC(131)
,
Methionine : CK(52) : AC(12)
,
Tryptophan : CK(322) : AC(30)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Gastroesophageal Reflux : CK(278) : AC(41)
Pharmacological Actions
:
Proton Pump Inhibitor : CK(36) : AC(13)
Additional Keywords
:
Superiority of Natural Substances versus Drugs : CK(826) : AC(164)
A form of vitamin B6 suppresses clinical seizures.
Click here to read the entire abstract
Pubmed Data
: Brain Dev. 1987;9(4):418-21. PMID:
3434717
Article Published Date
: Jan 01, 1987
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Epileptic Seizures : CK(47) : AC(6)
,
Tuberous Sclerosis : CK(20) : AC(2)
,
West Syndrome : CK(10) : AC(1)
A multi-vitamin/nutrient formula has therapeutic value in early-stage Alzheimer's diease.
Click here to read the entire abstract
Pubmed Data
: Am J Alzheimers Dis Other Demen. 2008 Dec-2009 Jan;23(6):571-85. Epub 2008 Dec 1. PMID:
19047474
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Carnitine, Acetyl-L- : CK(40) : AC(4)
,
Folic Acid : CK(542) : AC(77)
,
NAC (N-acetyl-L-cysteine) : CK(264) : AC(62)
,
SAMe (S-adenosylmethionine) : CK(89) : AC(17)
,
Vitamin B-6 : CK(412) : AC(48)
,
Vitamin E : CK(1285) : AC(221)
Diseases
:
Alzheimer's Disease : CK(886) : AC(160)
Anemia associated with myelofibrosis may respond positively pyridoxine hydrochloride.
Click here to read the entire abstract
Pubmed Data
: Bull World Health Organ. 2008 Mar;86(3):210-4. PMID:
707525
Article Published Date
: Mar 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Anemia : CK(89) : AC(12)
,
Myelofibrosis : CK(19) : AC(4)
Ascorbic acid, riboflavin and pyridoxine may have therapeutic value in various heredietary connective tissue diseases.
Click here to read the entire abstract
Pubmed Data
: Vopr Med Khim. 1988 Sep-Oct;34(5):99-104. PMID:
2905846
Article Published Date
: Sep 01, 1988
Study Type
: Human Study
Additional Links
Substances
:
Riboflavin (Vitamin B-2) : CK(77) : AC(13)
,
Vitamin B-6 : CK(412) : AC(48)
,
Vitamin C : CK(1274) : AC(238)
Diseases
:
Connective Tissue Diseases : CK(10) : AC(1)
,
Ehlers-Danlos Syndrome : CK(20) : AC(3)
,
Larsen Syndrome : CK(10) : AC(1)
,
Marfan Syndrome : CK(10) : AC(1)
Autistic children have lower levels of Vitamin C, and may not be able to convert Vitamin B-6 into its enzymatically active form: pyridoxal-5-phosphate.
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2004 Dec;10(6):1033-9. PMID:
15673999
Article Published Date
: Dec 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6 : CK(412) : AC(48)
,
Vitamin C : CK(1274) : AC(238)
Diseases
:
Autism : CK(1262) : AC(65)
B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.
Click here to read the entire abstract
Pubmed Data
: Int J Geriatr Psychiatry. 2011 Jul 21. Epub 2011 Jul 21. PMID:
21780182
Article Published Date
: Jul 21, 2011
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Alzheimer's Disease : CK(886) : AC(160)
,
Cognitive Decline/Dysfunction : CK(522) : AC(87)
,
High Homocysteine : CK(368) : AC(57)
,
Neurodegenerative Diseases : CK(1743) : AC(420)
Pharmacological Actions
:
Neuroprotective Agents : CK(962) : AC(480)
Common variable immonodeficiency is associated with vitamin B6 deficiency.
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2008 Mar;62(3):332-5. Epub 2007 Feb 21. PMID:
17311052
Article Published Date
: Mar 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Common variable immunodeficiency (CVID) : CK(60) : AC(6)
Dietary vitamin B6 consumption is inversely correlated to risk for Parkinsons disease.
Click here to read the entire abstract
Pubmed Data
: Neurology. 2006 Jul 25;67(2):315-8. PMID:
16864826
Article Published Date
: Jul 25, 2006
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Parkinson Disease : CK(543) : AC(79)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Ginger and Vitamin B6 are both effective in treating naseau and vomiting in pregnancy.
Click here to read the entire abstract
Pubmed Data
: Midwifery. 2008 Feb 11. PMID:
18272271
Article Published Date
: Feb 11, 2008
Study Type
: Human Study
Additional Links
Substances
:
Ginger : CK(310) : AC(89)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Naseau: Pregnancy-Associated : CK(21) : AC(3)
Heart failure patients have high rates of B-vitamin deficiency.
Click here to read the entire abstract
Pubmed Data
: J Am Diet Assoc. 2009 Aug;109(8):1406-10. PMID:
19631047
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
B-complex : CK(278) : AC(32)
,
Riboflavin (Vitamin B-2) : CK(77) : AC(13)
,
Thiamine (B-1) : CK(102) : AC(15)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Heart Failure : CK(711) : AC(97)
Higher consumption of folate may contribute to the prevention of peripheral arterial disease.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2003 Sep;133(9):2863-7. PMID:
12949378
Article Published Date
: Sep 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Peripheral Arterial Disease : CK(260) : AC(26)
,
Peripheral Vascular Diseases : CK(221) : AC(23)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Higher consumption of specific nutrients, including antioxidants (vitamin A, C, and E), vitamin B(6), fiber, folate, and omega-3 fatty acids have a significant protective effect against peripheral arterial disease.
Click here to read the entire abstract
Pubmed Data
: J Vasc Surg. 2008 Oct;48(4):897-904. Epub 2008 Jun 30. PMID:
18586439
Article Published Date
: Oct 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Fiber : CK(484) : AC(70)
,
Folate: Dietary : CK(62) : AC(7)
,
Omega-3 Fatty Acids : CK(3333) : AC(319)
,
Vitamin A : CK(371) : AC(58)
,
Vitamin B-6 : CK(412) : AC(48)
,
Vitamin C : CK(1274) : AC(238)
,
Vitamin E : CK(1285) : AC(221)
Diseases
:
Peripheral Arterial Disease : CK(260) : AC(26)
,
Peripheral Vascular Diseases : CK(221) : AC(23)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Homocysteine levels in the tear fluid and plasma of patients with primary open-angle glaucoma is often elevated, indicating that inadequate vitamin b levels (e.g. b6, b12, and folate) may contribute to the disease.
Click here to read the entire abstract
Pubmed Data
: Ophthalmic Res. 2008;40(5):249-56. Epub 2008 Apr 25. PMID:
18437035
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Glaucoma : CK(111) : AC(19)
,
High Homocysteine : CK(368) : AC(57)
Homocysteine levels may be elevated in obstructive sleep apnea.
Click here to read the entire abstract
Pubmed Data
: Chest. 2001 Sep;120(3):900-8. PMID:
11555527
Article Published Date
: Sep 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
High Homocysteine : CK(368) : AC(57)
,
Sleep Apnea: Central : CK(66) : AC(9)
Additional Keywords
:
Diseases that are Linked : CK(2122) : AC(270)
Hyperhomocysteinaemia, vascular related pregnancy complications respond favorably to vitamin supplementation in pregnant women of Pakistan.
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2010 Sep;60(9):741-5. PMID:
21381582
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
B-complex : CK(278) : AC(32)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Albuminuria: Pregnancy-Associated : CK(10) : AC(1)
,
Eclampsia : CK(10) : AC(1)
,
High Homocysteine : CK(368) : AC(57)
,
Infants: Low Birth Weight : CK(124) : AC(13)
,
Placental abruption : CK(10) : AC(1)
,
Pre-Eclampsia : CK(309) : AC(33)
,
Pregnancy Complications : CK(166) : AC(19)
L-arginine, folic acid, B6 and B12 may have therapeutic benefit in Buerger's disease.
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2006 Oct;12(4):427-39. PMID:
17000887
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
,
Folic Acid : CK(542) : AC(77)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Buerger Disease : CK(10) : AC(1)
Low levels of vitamin b-6 are associated with gastritis and gastric cancer.
Click here to read the entire abstract
Pubmed Data
: Gut. 1976 May;17(5):371-4. PMID:
1278721
Article Published Date
: May 01, 1976
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Gastric Cancer : CK(373) : AC(111)
,
Gastritis : CK(291) : AC(8)
Lowering homocysteine with folic acids, B-6 and B-12 may have a therapeutic effect on migraine headaches.
Click here to read the entire abstract
Pubmed Data
: Pharmacogenet Genomics. 2009 Jun;19(6):422-8. PMID:
19384265
Article Published Date
: Jun 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
High Homocysteine : CK(368) : AC(57)
,
Migraine Disorders : CK(486) : AC(58)
Additional Keywords
:
Diseases that are Linked : CK(2122) : AC(270)
Magnesium and Vitamin B-6 improve symptoms of Autism.
Click here to read the entire abstract
Pubmed Data
: Magnes Res. 2006 Mar;19(1):53-62. PMID:
16846101
Article Published Date
: Mar 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Magnesium : CK(826) : AC(120)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Autism : CK(1262) : AC(65)
Magnesium and vitamin B6 supplementation improves anxiety-related premenstrual symptoms.
Click here to read the entire abstract
Pubmed Data
: J Womens Health Gend Based Med. 2000 Mar;9(2):131-9. PMID:
10746516
Article Published Date
: Mar 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Magnesium : CK(826) : AC(120)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Premenstrual syndrome : CK(160) : AC(16)
Moderate consumption of riboflavin may be protective against postpartum depression.
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2000 Jul 31;155(2):115-20. PMID:
16815556
Article Published Date
: Jul 31, 2000
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Riboflavin (Vitamin B-2) : CK(77) : AC(13)
,
Vitamin B-12 : CK(752) : AC(94)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Postpartum Depression : CK(211) : AC(24)
ncreased folate and vitamin B6 intakes seem to reduce homocysteine concentrations among transplant recipients with normal renal function, and could contribute to reducing the risk of chronic allograft dysfunction development.
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 1996 Mar;63(3):392-8. PMID:
18089344
Article Published Date
: Mar 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
High Homocysteine : CK(368) : AC(57)
,
Kidney Transplant : CK(65) : AC(8)
The abnormally high plasma level of vitamin B6 in children with autism may be due to an enzyme dysfunction with pyridoxal kinase.
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2006 Jan-Feb;12(1):59-63. PMID:
16494569
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Pyridoxal-5-Phosphate : CK(10) : AC(2)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Autism Spectrum Disorders : CK(1140) : AC(108)
The intake of folate and vitamin B6 above the current recommended dietary allowance may be important in the primary prevention of coronary artery disease among women.
Click here to read the entire abstract
Pubmed Data
: Endocr Pract. 2003 Sep-Oct;9(5):363-9. PMID:
9459468
Article Published Date
: Sep 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
,
Vitamin B-6 : CK(412) : AC(48)
Diseases
:
Coronary Artery Disease : CK(1305) : AC(136)
,
Myocardial Infarction : CK(2632) : AC(117)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
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