Vitamin C

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View the Evidence: Substances

"Vitamins C and E and their combination are safe and effective treatments for reducing the severity of RLS in hemodialysis patients over the short-term."

Pubmed Data : Sleep Med. 2012 Feb 6. Epub 2012 Feb 6. PMID: 22317944
Article Published Date : Feb 06, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Restless Leg Syndrome: Hemodialysis Patients : CK(10) : AC(1)

A combination of ascorbigen (a food derived form of vitamin c) and broccoli powder reduces pain sensivitiy and improves quality of life in patients with fibromyalgia.

Pubmed Data : Altern Med Rev. 2000 Oct;5(5):455-62. PMID: 11056415
Article Published Date : Oct 01, 2000
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Vitamin C : CK(1274) : AC(238)
Diseases : Fibromyalgia : CK(537) : AC(57)

A combination of nutrients improves age-related macular degeneration.

Pubmed Data : Ophthalmology. 2008 Feb;115(2):324-333.e2. Epub 2007 Aug 22. PMID: 17716735
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Substances : Astaxanthin : CK(353) : AC(117), Carotenoids : CK(1055) : AC(213), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), Zinc : CK(870) : AC(127)
Diseases : Macular Degeneration : CK(162) : AC(23)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

A combination of quercetin, ascorbyl palmitate and vitamin D appears to safely offer relief of symptomatic diabetic neuropathy.

Pubmed Data : J Diabetes Complications. 2005 Sep-Oct;19(5):247-53. PMID: 16112498
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Ascorbyl Palmitate : CK(10) : AC(1), Quercetin : CK(318) : AC(136), Vitamin C : CK(1274) : AC(238), Vitamin D : CK(1682) : AC(238)
Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Diabetic Neuropathies : CK(203) : AC(32), Peripheral Neuropathies : CK(394) : AC(31)
Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208)

A high dietary intake of vitamin C, or foods rich in this vitamin, may prevent COPD.

Pubmed Data : Indian J Dent Res. 2007 Oct-Dec;18(4):148-51. PMID: 11991883
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238)
Diseases : Chronic Obstructive Pulmonary Disease : CK(269) : AC(42)

A multi antioxidative treatment in chronic hepatitis C virus patients is well tolerated and therapeutic.

Pubmed Data : J Clin Gastroenterol. 2005 Sep;39(8):737-42. PMID: 16082287
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid : CK(384) : AC(82), Antioxidant formulas : CK(487) : AC(73), Glutathione : CK(61) : AC(16), Licorice : CK(257) : AC(81), Milk Thistle : CK(226) : AC(55), Schisandra : CK(129) : AC(43), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Hepatitis C : CK(401) : AC(62)

A multi-nutrient mixture of soy extract, fish protein polysaccharides, extracts from white tea, grape seed and tomato, vitamins C and E as well as zinc and chamomile extract improves signs of skin aging in post-menopausal women.

Pubmed Data : Eur J Clin Nutr. 2006 Oct;60(10):1201-6. Epub 2006 May 3. PMID: 16670692
Article Published Date : Oct 01, 2006
Study Type : Human Study
Additional Links
Substances : Chamomile : CK(95) : AC(18), Fish extract : CK(32) : AC(4), Grape Seed Extract : CK(168) : AC(57), Soy : CK(1672) : AC(347), Tomato : CK(271) : AC(47), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), White Tea : CK(17) : AC(6), Zinc : CK(870) : AC(127)
Diseases : Aging Skin : CK(360) : AC(86), Postmenopausal Disorders : CK(285) : AC(35)

A multi-nutrient mixture of vitamin C, vitamin E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and pycnogenol improves visible signs of ageing in women 45-73 years of age.

Pubmed Data : J Dermatolog Treat. 2004 Jul;15(4):222-6. PMID: 15764035
Article Published Date : Jul 01, 2004
Study Type : Human Study
Additional Links
Substances : Amino Acids : CK(100) : AC(16), Blueberry : CK(140) : AC(39), Glycosaminoglycans : CK(12) : AC(2), Pycnogenol (Pine Bark) : CK(385) : AC(61), Selenium : CK(574) : AC(94), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), Zinc : CK(870) : AC(127)
Diseases : Aging Skin : CK(360) : AC(86), Skin Diseases : CK(46) : AC(9)

Abdominal aortic aneurysm is associated with oxidative stress and/or antioxidant depletion.

Pubmed Data : Proc Soc Exp Biol Med. 1987 Feb;184(2):138-43. PMID: 3809168
Article Published Date : Feb 01, 1987
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas : CK(487) : AC(73), Vitamin C : CK(1274) : AC(238)
Diseases : Aortic Aneurysm : CK(52) : AC(6)

Adding vitamin C to one-week triple therapy can reduce the dosage of clarithromycin, but preserve the high eradication efficacy for clarithromycin susceptible H. pylori infection.

Pubmed Data : Hepatogastroenterology. 2007 Jan-Feb;54(73):320-4. PMID: 17419283
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238)
Diseases : Duodenal Ulcer : CK(89) : AC(26), Gastric Ulcer : CK(246) : AC(91), Helicobacter Pylori Infection : CK(305) : AC(61)
Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316), Anti-Ulcer Agents : CK(162) : AC(57)
Additional Keywords : Drug: Amoxicillin : CK(60) : AC(6), Drug: Omeprazole : CK(90) : AC(15)

Adoptive immunotherapy causes severe vitamin C deficiency.

Pubmed Data : Cancer Res. 1987 Aug 1;47(15):4208-12. PMID: 3496958
Article Published Date : Aug 01, 1987
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238)
Diseases : Cancers: All : CK(9062) : AC(2869), Immunotherapy: Adoptive : CK(10) : AC(1)

An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men.

Pubmed Data : Am J Clin Nutr. 2010 Apr;91(4):1044-59. Epub 2010 Feb 24. PMID: 20181810
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Substances : Green Tea : CK(930) : AC(294), Omega-3 Fatty Acids : CK(3333) : AC(319), Resveratrol : CK(977) : AC(590), Tomato : CK(271) : AC(47), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Adiponectin: Low Levels : CK(88) : AC(25), Endothelial Dysfunction : CK(897) : AC(173), Inflammation : CK(1077) : AC(363), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318)

An herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children.

Pubmed Data : Arch Pediatr Adolesc Med. 2004 Mar;158(3):217-21. PMID: 14993078
Article Published Date : Mar 01, 2004
Study Type : Human Study
Additional Links
Substances : Bee Propolis : CK(220) : AC(83), Echinacea : CK(469) : AC(88), Vitamin C : CK(1274) : AC(238)
Diseases : Childhood Infections : CK(275) : AC(29), Common Cold : CK(473) : AC(56), Upper Respiratory Infections : CK(972) : AC(92)

Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration.

Pubmed Data : Am J Ophthalmol. 2005 Dec;140(6):1020-6. PMID: 16376645
Article Published Date : Dec 01, 2005
Study Type : Human Study
Additional Links
Substances : beta-Carotene : CK(217) : AC(38), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Macular Degeneration : CK(162) : AC(23)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Antioxidant therapy with pine bark, vitamin C and vitamin E may be beneficial in the treatment of drug-refractory migraine possibly reducing headache frequency and severity.

Pubmed Data : Headache. 2006 May;46(5):788-93. PMID: 16643582
Article Published Date : May 01, 2006
Study Type : Human Study
Additional Links
Substances : Pine Bark Extract : CK(395) : AC(62), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Migraine Disorders : CK(486) : AC(58)

Antioxidant vitamin levels are depleted in sickle cell disorders, indicating that supplementation may be of value.

Pubmed Data : Natl Med J India. 2007 Jan-Feb;20(1):11-3. PMID: 17557515
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Sickle Cell Anemia : CK(31) : AC(4)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Antioxidants such as carnosine and vitamin C may be effective therapies in reducing oxidative stress associated with autism.

Pubmed Data : Altern Ther Health Med. 2004 Nov-Dec;10(6):22-36; quiz 37, 92. PMID: 15624347
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas : CK(487) : AC(73), Carnisone : CK(10) : AC(1), Vitamin C : CK(1274) : AC(238)
Diseases : Autism : CK(1262) : AC(65)

Ascorbic acid appears to reduce symptoms in children with autism.

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 1993 Sep;17(5):765-74. PMID: 8255984
Article Published Date : Sep 01, 1993
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238)
Diseases : Autism : CK(1262) : AC(65)

Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.

Pubmed Data : Circulation. 1996 Mar 15;93(6):1107-13. PMID: 8653830
Article Published Date : Mar 15, 1996
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238)
Diseases : Atherosclerosis : CK(523) : AC(77), Coronary Artery Disease : CK(1305) : AC(136), Endothelial Dysfunction : CK(897) : AC(173)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Ascorbic acid, riboflavin and pyridoxine may have therapeutic value in various heredietary connective tissue diseases.

Pubmed Data : Vopr Med Khim. 1988 Sep-Oct;34(5):99-104. PMID: 2905846
Article Published Date : Sep 01, 1988
Study Type : Human Study
Additional Links
Substances : Riboflavin (Vitamin B-2) : CK(77) : AC(13), Vitamin B-6 : CK(412) : AC(48), Vitamin C : CK(1274) : AC(238)
Diseases : Connective Tissue Diseases : CK(10) : AC(1), Ehlers-Danlos Syndrome : CK(20) : AC(3), Larsen Syndrome : CK(10) : AC(1), Marfan Syndrome : CK(10) : AC(1)

Autistic children have lower levels of Vitamin C, and may not be able to convert Vitamin B-6 into its enzymatically active form: pyridoxal-5-phosphate.

Pubmed Data : J Altern Complement Med. 2004 Dec;10(6):1033-9. PMID: 15673999
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Substances : Vitamin B-6 : CK(412) : AC(48), Vitamin C : CK(1274) : AC(238)
Diseases : Autism : CK(1262) : AC(65)

Beta-carotene, vitamin C and vitamin E deficiencies may play a role in the pathogenesis of thyroid cancer.

Pubmed Data : Cancer. 1997 Jun 1;79(11):2186-92. PMID: 9179066
Article Published Date : Jun 01, 1997
Study Type : Human Study
Additional Links
Substances : beta-Carotene : CK(217) : AC(38), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Thyroid Cancer : CK(162) : AC(32)

Breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements.

Pubmed Data : Int J Cancer. 2009 Apr 1;124(7):1637-43. PMID: 19089916
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas : CK(487) : AC(73), beta-Carotene : CK(217) : AC(38), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Breast Cancer: Prevention : CK(525) : AC(73)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Telomere Length : CK(18) : AC(5)

Carotenoids, Vitamin C and E, reduce the risk of cataracts in women.

Pubmed Data : Arch Ophthalmol. 2008 Jan;126(1):102-9. PMID: 18195226
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Carotenoids : CK(1055) : AC(213), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Cataract : CK(182) : AC(55)

Chronic, oral, low-dose vitamin C supplementation equilibrates autonomic function following change in posture with those of non-sickle cell anemia subjects..

Pubmed Data : Pathophysiology. 2008 Jun ;15(1):25-30. Epub 2008 Jan 29. PMID: 18234480
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(1274) : AC(238)
Diseases : Sickle Cell Anemia : CK(31) : AC(4)

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