Vitamin C

Name	AC	CK
Oxidative Stress	68	281
Endothelial Dysfunction	13	107
Inflammation	18	100
Vitamin C Deficiency	21	94
Diabetes Mellitus: Type 2	7	70
Cardiovascular Diseases	9	65
Lung Cancer	12	61
Hypertension	6	53
Pancreatic Cancer	5	53
C-Reactive Protein	5	50
DNA damage	18	50
Sickle Cell Anemia	5	41
Atrial Fibrillation	2	40
Cortisol: High	4	40
Smoking	4	40
Breast Cancer	19	36
Tuberculosis	5	36
Osteoporosis	6	34
Obesity	5	33
Prostate Cancer	5	33
Asthma	4	32
Aging Skin	4	31
Cancers: All	18	31
Coronary Artery Disease	4	31
Endometriosis	4	31
Macular Degeneration	4	31
Autism	3	30
Cardiac Surgery	2	30
Diabetes Mellitus: Type 2: Prevention	3	30
Hemodialysis	3	30
Hepatitis A	3	30
Hepatitis C	3	30
Insulin Resistance	3	30
Peripheral Vascular Diseases	3	30
Pre-Eclampsia	3	30
Upper Respiratory Infections	3	30
Aging	7	28
Lead Poisoning	14	28
Gastric Cancer	6	25
Cataract	5	24
Alcohol Toxicity	8	23
Atherosclerosis	4	22
Helicobacter Pylori Infection	3	22
Common Cold	3	21
Cystic Fibrosis	3	21
Endometrial Cancer	2	21
Anxiety Disorders	2	20
Aortic Aneurysm	2	20
Cervical Neoplasia	1	20
Chronic Obstructive Pulmonary Disease	2	20
Ehlers-Danlos Syndrome	2	20
Esophageal Cancer	2	20
Lipid Peroxidation	8	20
Peripheral Arterial Disease	2	20
Prostate Cancer: Prevention	1	20
Urinary Tract Infections	2	20
Sepsis	7	19
Bone Fractures	6	18
Radiation Induced Illness	5	18
Cervical Cancer	6	17
Air Pollution Linked Toxicity	3	16
Colorectal Cancer	5	16
Pneumonia	5	16
Prenatal Chemical Exposures	4	16
Cholesterol: Oxidation	5	15
Hyperlipidemia	4	15
Liver Cancer	9	15
Alzheimer's Disease	8	14
Diabetic Complications	3	14
Hyperthyroidism	3	14
Stress	3	14
Arteriosclerosis	3	13
Neuralgia: Post Herpetic	2	13
Triglycerides: Elevated	3	13
Acute Myeloid Leukemia	3	12
Anemia	2	12
Cancer Metastasis	2	12
Chemotherapy and Radiation Toxicity	2	12
Colon Cancer	9	12
Gastric Ulcer	2	12
Histamine: Elevated	2	12
Infertility: Female	2	12
Infertility: Male	2	12
Ischemia	2	12
Lipopolysaccharide-Induced Toxicity	2	12
Melanoma	8	12
Nephropathy	2	12
Septic Shock	3	12
Thyroid Cancer	3	12
Autism Spectrum Disorders	2	11
Barrett Esophagus	3	11
Hyperuricemia	3	11
Migraine Disorders	2	11
Non-Hodgkin Lymphoma	2	11
Periodontitis	2	11
Surgery: All	2	11
Ultraviolet Radiation Induced Damage	2	11
A1C	1	10
Adiponectin: Low Levels	1	10
Advanced Glycation End products (AGE)	1	10
Anemia: Hemolytic	1	10
Anemia: Iron Deficiency	1	10
Aortic Stenosis	1	10
Aspirin-Induced Toxicity	1	10
Asthma: Bronchial	1	10
Athletic Performance	1	10
Athletic Performance: Recovery	1	10
Attention Deficit Disorder with Hyperactivity	1	10
Back Pain	1	10
Breast Cancer: Prevention	1	10
COPD	1	10
Catecholamines: Elevated	1	10
Childhood Cognitive Disorders	1	10
Childhood Deficiencies	1	10
Childhood Infections	1	10
Chronic Kidney Disease (CKD)	1	10
Chronic Obstructive Lung Disease	1	10
Cold: Common	1	10
Connective Tissue Diseases	1	10
Coronary Bypass Surgery	1	10
Diabetes: Glycation/A1C	1	10
Diabetic Neuropathies	1	10
Diesel Exhaust Particle Toxicity	1	10
Duodenal Ulcer	1	10
Epidermolysis Bullosa	1	10
Exercise-Induced Tissue Damage	1	10
Fibromyalgia	1	10
Gastrointestinal Infections	1	10
Genital Warts	1	10
Gestational Diabetes	1	10
Graves Disease	1	10
Head and Neck Cancer	1	10
Headache: Migraine	1	10
Heart Failure	1	10
Herpes Simplex Virus Type 1	1	10
High Cortisol	1	10
High Homocysteine	1	10
Hip Fracture	1	10
Hypertension: Sickle Cell Anemia	1	10
Immunotherapy: Adoptive	1	10
Influenza A	7	10
Ischemic Heart Disease	1	10
Kidney Cancer	1	10
Kidney Stones	1	10
Knee Replacement Surgery: Adverse Effects	1	10
Larsen Syndrome	1	10
Leukoplakia	1	10
Lichen Planus	1	10
Lymphoma: Mantle Cell	1	10
Marfan Syndrome	1	10
Metabolic Syndrome X	1	10
Mortality: All-Cause	1	10
Muscle Damage: Exercise-Induced	1	10
Myelodysplastic Syndrome	1	10
NSAID-induced toxicity	1	10
Neck Pain	1	10
Neutrophils: Elevated	1	10
Nonalcoholic fatty liver disease (NAFLD)	1	10
Oral Lichen Planus	1	10
Perfluorinated Compound Toxicity	1	10
Periodontal Wound Healing	1	10
Peripheral Neuropathies	1	10
Postmenopausal Disorders	1	10
Postpartum Depression	1	10
Precancerous Conditions	1	10
Pregnancy: Prevention of Problems	1	10
Pregnancy: Urinary Tract Infections	1	10
Purpura: Thrombocytopenic	1	10
Quality of Life: Poor	1	10
Raynaud Disease	1	10
Reflex Sympathetic Dystrophy	1	10
Respiratory Infections	1	10
Restless Leg Syndrome: Hemodialysis Patients	1	10
Rheumatoid Arthritis	1	10
Rhinosinusitis	1	10
Sclerosis: Systemic	1	10
Sitting Sickness	1	10
Skin Diseases	1	10
Sleep Apnea: Central	1	10
Stroke: Prevention	1	10
Thalassemia	1	10
Trauma Patients	1	10
Varicocele	1	10
Vision Loss	1	10
Xerostomia	1	10
Promyelocytic leukemia	5	9
Pyrethroid Insecticide Induced Toxicity	4	8
Cadmium Poisoning	4	7
Metabolic Diseases	3	7
Nicotine/Tobacco Toxicity	4	7
Celiac Disease	2	6
Cognitive Decline/Dysfunction	3	6
Fluoride Toxicity	3	6
Hypothyroidism	3	6
Nickel Poisoning	3	6
Ovarian Cancer	3	6
Pesticide Toxicity	3	6
Tumors	4	6
Werner Syndrome	3	6
Advanced Glycation Endproduct (AGE) Formation	1	5
Aflatoxicosis	3	5
Breast Cancer: Triple Negative	4	5
Cancers: Drug Resistant	4	5
Chemotherapy-Induced Toxicity: Doxorubicin	3	5
Fructose-Induced Toxicity	1	5
Hearing Loss	2	5
Leukemia	4	5
Leukemia: Acute promyelocytic leukemia	1	5
Lymphoma	4	5
Melanoma: Metastasis	3	5
Melanoma: Metastatic	4	5
Myocardial Infarction	3	5
Neurodegenerative Diseases	4	5
Neutrophils: Damaged	1	5
Scurvy	3	5
Wound Healing	3	5
Acetaminophen (Tylenol) Toxicity	2	4
Aluminum Toxicity	2	4
Brain Inflammation	2	4
Charcot-Marie-Tooth Disease	2	4
Diabetes Mellitus: Type 1	2	4
Drug-Induced Toxicity: Methotrexate	2	4
Dyslipidemias	2	4
Gastrointestinal Inflammation	2	4
Learning disorders	2	4
Memory Disorders	2	4
Mycobacterium tuberculosis	3	4
Periodontal Diseases	2	4
Pesticide-Induced Toxicity: Organochlorines	2	4
Sperm Quality: Low	2	4
Dementia	2	3
Endothelial Damage	2	3
Fatigue: Cancer-Associated	1	3
Gallstones	2	3
Gingivitis	1	3
Glioblastoma	2	3
High Cholesterol	2	3
Insomnia	1	3
Kidney Damage	2	3
Movement Disorders	1	3
Parkinson's Disease	3	3
Parkinsonism	1	3
Parvovirus	1	3
Skin Cancer	2	3
Staphylococcus aureus infection	2	3
Allergic Airway Diseases	1	2
Allodynia	1	2
Alloxan toxicity	1	2
Amebiasis	1	2
Anxiety	1	2
Arsenic Poisoning	1	2
Ascites	1	2
Azo compound toxicity	1	2
Barium Toxicity	1	2
Benzene Toxicity	2	2
Bisphenol Toxicity	1	2
Blood-Brain-Barrier Disorders	1	2
Brain: Oxidative Stress	1	2
Breast Cancer: Estrogen	1	2
Breast Cancer: Metastatic	1	2
Breast Cancer: estrogen receptor alpha-positive	1	2
Breastfeeding Concerns: Chemical Exposure	1	2
Cancers: Multi-Drug Resistant	2	2
Candida Albicans	1	2
Candidiasis	1	2
Chemical Exposure: Nitrobenzene	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Cholestasis	1	2
Cytomegalovirus Infections	1	2
Degenerative Disk Disease	2	2
Dental Plaque	1	2
Depression	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Neuropathy	1	2
Emphysema: Pulmonary	1	2
Encephalitis	1	2
Eosinophilia	1	2
Eye Damage	1	2
Fetal Origin of Adult Disease	1	2
Gingival melanin pigmentation	1	2
Glioma	1	2
H1N1 Infection	1	2
H3N2 Infection	1	2
Hearing Loss: Noise-Induced	1	2
Hepatitis	1	2
Hepatoma	1	2
Human Influenza	2	2
Hydrogen Peroxide Induced Toxicity	2	2
Hypercholesterolemia	1	2
Hyperglycemia	1	2
Hypertension: Pulmonary	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Failure	1	2
Liver Damage	1	2
Liver Damage: Drug-Induced	1	2
Liver Fibrosis	1	2
Low Immune Function: Natural Killer Cells	1	2
Lung Cancer: Metastatic	1	2
Lung Damage	1	2
Lung Diseases	1	2
Malignant Melanoma	1	2
Memory Disorders: Drug-Induced	1	2
Memory Loss	1	2
Multiple Myeloma	1	2
Neuropathic Pain	1	2
Osteoarthritis	2	2
Parainfluenza Virus Infections	1	2
Paramyxoviridae Infections	1	2
Pesticide-Induced Toxicity: Organophosphates	1	2
Polychlorinated biphenyl toxicity	1	2
Prophyrias	1	2
Prostatic Hyperplasia: Benign	1	2
Radiation Induced Illness: Bone Marrow	1	2
Radiation-Induced Illness: Americium	1	2
Radiation-Induced Illness: Plutonium	1	2
Radiation-Induced Illness: Radioiodine (Iodine-131)	1	2
Radiotherapy	1	2
Seizures	1	2
Smoking: Pulmonary	1	2
Smoldering multiple myeloma (SMM)	1	2
Spinal Cord Injuries	1	2
Statin-Induced Pathologies	1	2
Stroke: Attenuation/Recovery	1	2
Surgery: Anesthesiology	1	2
Tendon Injury	1	2
Testicular Diseases	1	2
Tin Poisoning	1	2
Traumatic Brain Injury	1	2
Ulcerative Colitis	1	2
Acinetobacter baumannii infection	1	1
Acute T cell Leukemias	1	1
Aging: Brain	1	1
Anemia: Sickle Cell	1	1
Arterial Plaque	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Bladder Cancer	1	1
Blood Storage Problems	1	1
Bone Diseases	1	1
Breast Cancer Stem Cells	1	1
Bronchial Asthma	1	1
Burkitt Lymphoma	1	1
Burns	1	1
Candida Infection	1	1
Cartilage Diseases	1	1
Chagas Disease	1	1
Chronic Pain	1	1
Colorectal Cancer: Prevention	1	1
Complex Regional Pain Syndrome: Type I	1	1
Congestive Heart Failure	1	1
Corneal Neovascularization	1	1
Corticosteroid-Induced Toxicity	1	1
Encephalitis: Herpes Simplex	1	1
Eye Diseases: Vitreous Disorders	1	1
Gastrointestinal Diseases	1	1
Glaucoma	1	1
Gout	2	1
HSV-1	1	1
Heat Stroke	1	1
Herpes Simplex Virus Type 2	1	1
Hormone Imbalances	1	1
Human Papillomavirus (HPV)	1	1
Human T-Cell Lymphotrophic Virus type 1 associated disease	1	1
Human T-cell leukemia virus type I (HTLV-I)	1	1
Infection: Antibiotic Resistant	1	1
Iron Overload	1	1
Iron Poisoning	1	1
Kidney Diseases	1	1
Laryngeal Cancer	1	1
Liver Diseases	1	1
Lyme Borreliosis	1	1
Lyme Disease	1	1
Lymphoma: T-cell	1	1
Menstrual Migraine	1	1
Mesothelioma	1	1
Migraine: Menstrual Cycle Induced	1	1
Mineral Imbalances	1	1
Mitochondrial Diseases	1	1
Neuralgia	1	1
Neuroblastoma	1	1
Nutritional Deficiencies	1	1
Organ Transplantation: Cornea	1	1
Para-phenylenediamine Induced Toxicity	1	1
Petroleum Exposure And Toxicity	1	1
Polio	1	1
Polycyclic aromatic hydrocarbon (PAH) toxicity	1	1
Pseudomonas Infections	1	1
Pseudomonas aeruginosa	1	1
Psychiatric Disorders	1	1
Rosacea	1	1
Skin Diseases: Photo-Aging	1	1
Squamous cell carcinoma	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Stem Cell Transplant	1	1
Sunburn	1	1
Tetanus	1	1
Vitamin D Deficiency	1	1
Wound Healing: Delayed	1	1

Name	AC	CK
Antioxidants	192	860
Chemopreventive	16	87
Anti-Inflammatory Agents	22	83
Interleukin-6 Downregulation	9	75
Cardioprotective	12	63
Antiproliferative	37	54
Apoptotic	33	48
Chemotherapeutic	18	46
Tumor Necrosis Factor (TNF) Alpha Inhibitor	10	45
Malondialdehyde Down-regulation	9	44
Neuroprotective Agents	23	40
Radioprotective	12	35
Prophylactic Agents	4	33
Renoprotective	14	33
Immunomodulatory	6	30
Analgesics	5	25
Antiviral Agents	9	24
Hepatoprotective	11	22
NF-kappaB Inhibitor	11	21
Telomere Protective	2	20
Hypolipidemic	5	17
Anti-metastatic	10	16
Chemosensitizer	13	16
Anticarcinogenic Agents	4	15
Hypoxia-inducible factor-1 (HIF-1) inhibitor	4	15
Anti-Bacterial Agents	4	14
Antimicrobial	4	14
Cyclooxygenase 2 Inhibitors	3	14
Cytoprotective	6	14
Hypoglycemic Agents	3	14
Anti-Anxiety Agents	2	12
Anti-Glycation Agents	2	12
Immunostimulatory	2	12
Telomerase Upregulation	2	12
Anti-atherogenic	2	11
Antihypertensive Agents	2	11
Cell cycle arrest	10	11
Chemoprotective Agents	6	11
Gastrointestinal Agents	2	11
Heat Shock Protein Inducer	2	11
MicroRNA modulator	2	11
Photoprotective	2	11
Anti-Apoptotic	5	10
Anti-Infective Agents	1	10
Anti-Ulcer Agents	1	10
Anticholesteremic Agents	1	10
Enzyme Inhibitors	1	10
Immune Enhancing Properties	1	10
Insulin Sensitizers	1	10
Monocyte chemotattractant protein-1 (MCP-1) Inhibitor	1	10
Nitric Oxide Enhancer	1	10
Prostaglandin PGE2 downregulation	1	10
Uricosuric Agents	1	10
Vasodilator Agents	1	10
Cytotoxic	6	9
Interleukin-1 beta downregulation	3	9
Antineoplastic Agents	6	8
Genoprotective	5	8
Autophagy Up-regulation	2	7
Tumor Suppressor Protein p53 Upregulation	6	7
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	6
Chondroprotective	1	5
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	4	5
Vascular Endothelial Growth Factor A Inhibitor	3	5
Acetylcholinesterase Inhibitor	2	4
Superoxide Dismutase Up-regulation	2	4
Antimutagenic Agents	3	3
Cytotoxicity	2	3
Osteoprotective	2	3
Radiosensitizer	2	3
Regenerative	2	3
Vascular Endothelial Growth Factor Inhibitors	2	3
Anti Inflammatory	1	2
Anti-Tumor	1	2
Antidepressive Agents	1	2
Antinoceceptive	1	2
Antioxidant	1	2
Autophagy Inhibitors	1	2
Bcl-2 protein down-regulation	2	2
Cholinesterase Inhibitors	1	2
Gastroprotective	1	2
Heme oxygenase-1 up-regulation	1	2
Histamine down-regulation	1	2
Interferon Gamma Reducer	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Neurominidase Inhibitor	2	2
Nrf2 activation	1	2
Antifungal Agents	1	1
Antiprotozoal Agents	1	1
Caspase-3 Inhibition	1	1
Cell Differentiation Inducer	1	1
Gene Protective	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Histone deacetylase inhibitor	1	1
Matrix Metalloproteinases Inhibitors	1	1
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	1
Nitric Oxide Inhibitor	1	1
P21 Activation	1	1
Spermatogenic	1	1

[+]

Lipoprotein(a) and vitamin C impair development of breast cancer tumors.Aug 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biofactors. 2008;33(1):13-24. PMID: 19276533

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Pubmed Data : Mol Reprod Dev. 2002 Mar;61(3):385-97. PMID: 11835584

Article Published Date : Mar 01, 2002

Study Type : Animal Study

Additional Links

Substances : Vitamin C, Vitamin E

Diseases : Infertility: Female

Pharmacological Actions : Antioxidants

[+]

Oral intake of vitamin C prevents acute pulmonary oxidative stress and inflammation caused by zinc oxide nanoparticles.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Occup Health. 2015 ;57(2):118-25. Epub 2015 Aug 10. PMID: 25735507

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Hum Exp Toxicol. 2016 Dec 9. Epub 2016 Dec 9. PMID: 27941167

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2015 Sep ;10(3):901-906. Epub 2015 Jun 23. PMID: 26622412

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biomed Phys Eng. 2015 Jun ;5(2):59-66. Epub 2015 Jun 1. PMID: 26157731

Article Published Date : May 31, 2015

Study Type : Animal Study

Additional Links

Substances : Vitamin A, Vitamin C, Vitamin E

Diseases : Radiotherapy

Pharmacological Actions : Radioprotective

Additional Keywords : Supplementation

[+]

These findings indicate a synergistic protective effect of ferulic acid and ascorbic acid on lipid peroxidation and antioxidant defense system during ISO-induced myocardial infarction.Jan 31, 2006

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Pubmed Data : Mol Cell Biochem. 2006 Feb ;283(1-2):139-46. PMID: 16444596

[+]

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Pubmed Data : Pharmacol Biochem Behav. 2015 Jul 6 ;136:13-20. Epub 2015 Jul 6. PMID: 26159088

Article Published Date : Jul 05, 2015

Study Type : Animal Study

Additional Links

Substances : Berberine, Vitamin C

Diseases : Alcohol Toxicity , Cognitive Decline/Dysfunction, Memory Disorders: Drug-Induced, Oxidative Stress

Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents

[+]

Vitamin A, C and E reduce azo-dye binding protein in liver of rats.Apr 01, 2010

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Pubmed Data : Indian J Exp Biol. 2010 Apr;48(4):373-7. PMID: 20726335

Article Published Date : Apr 01, 2010

Study Type : Animal Study

Additional Links

Substances : Vitamin A, Vitamin C, Vitamin E

Diseases : Azo compound toxicity

Pharmacological Actions : Antioxidants

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Vitamin C administration could be used to reduce acrylamide-induced neurotoxicity.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Basic Clin Neurosci. 2018 Jan-Feb;9(1):27-34. PMID: 29942437

Pubmed Data : Hum Exp Toxicol. 2001 Dec;20(12):619-23. PMID: 11936575

Article Published Date : Dec 01, 2001

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Fluoride Toxicity

[+]

Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female rats.Jul 01, 2009

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Pubmed Data : Carcinogenesis. 2009 Jul ;30(7):1202-8. Epub 2009 Apr 30. PMID: 19406931

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Alpha-naphthoflavone, Vitamin C

Diseases : Breast Cancer: Estrogen, Breast Cancer: estrogen receptor alpha-positive

Pharmacological Actions : Antioxidants, Chemopreventive

[+]

Vitamin C and Baicalin inhibits tumor growth by enhancing the antioxidant capacity in vivo.Aug 31, 2015

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Pubmed Data : J BUON. 2015 Sep-Oct;20(5):1368-72. PMID: 26537087

Article Published Date : Aug 31, 2015

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Pubmed Data : Acta Ortop Bras. 2018 Mar-Apr;26(2):82-85. PMID: 29983622

Article Published Date : Feb 28, 2018

Study Type : Animal Study

Additional Links

Substances : Hyaluronic Acid, Vitamin C

Diseases : Tendon Injury

[+]

Vitamin C and Nigella sativa oil proved to have synergistic nephro-protective effect.Sep 30, 2012

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Pubmed Data : Pak J Pharm Sci. 2012 Oct ;25(4):727-30. PMID: 23009987

Article Published Date : Sep 30, 2012

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed), Vitamin C

Diseases : Chemotherapy-Induced Toxicity: Gentamicin, Oxidative Stress

Pharmacological Actions : Antioxidants, Chemoprotective Agents

Additional Keywords : Natural Substance Synergy, Plant Oils

[+]

Vitamin C and rosemary leaf extract showed ameliorative potential to reduce tissue accumulation of cadmium and associated oxidative stress.Oct 31, 2015

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Pubmed Data : J Environ Biol. 2015 Nov ;36(6):1401-8. PMID: 26688980

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Pubmed Data : Biomed Pharmacother. 2016 Sep 22 ;84:314-322. Epub 2016 Sep 22. PMID: 27665477

Article Published Date : Sep 21, 2016

Study Type : Animal Study

Additional Links

Substances : Vitamin C, Vitamin E

Diseases : Kidney Damage: Drug-Induced

Pharmacological Actions : Antioxidants, Renoprotective

Problem Substances : Diclofenac

[+]

Vitamin C and vitamin E protect the rat testes from cadmium-induced reactive oxygen species.Feb 29, 2004

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Pubmed Data : Mol Cells. 2004 Feb 29;17(1):132-9. PMID: 15055539

Article Published Date : Feb 29, 2004

Study Type : Animal Study

Additional Links

Substances : Vitamin C, Vitamin E

Diseases : Cadmium Poisoning

[+]

Vitamin C and vitamin E supplementation alleviates oxidative stress induced by dexamethasone and improves fertility of breeder roosters.Jul 31, 2016

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Pubmed Data : Anim Reprod Sci. 2016 Aug ;171:1-6. Epub 2016 Apr 4. PMID: 27297178

Article Published Date : Jul 31, 2016

Study Type : Animal Study

Additional Links

Substances : Vitamin C, Vitamin E

Diseases : Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Problem Substances : Dexamethasone

[+]

Vitamin C at high concentrations induces cytotoxicity in malignant melanoma but promotes tumor growth at low concentrations.Mar 29, 2017

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Pubmed Data : Mol Carcinog. 2017 Mar 30. Epub 2017 Mar 30. PMID: 28370562

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Med Sci. 2017 ;14(1):97-101. Epub 2017 Jan 15. PMID: 28138314

Pubmed Data : Exp Gerontol. 2015 Dec ;72:192-203. Epub 2015 Oct 29. PMID: 26521679

Article Published Date : Nov 30, 2015

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Oxidative Stress, Werner Syndrome

Pharmacological Actions : Antioxidants

Additional Keywords : Gene Expression Regulation

[+]

Vitamin C could prevent the adverse effects of bisphenol A on rat ovary.May 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Reprod Biomed (Yazd). 2016 Jun ;14(6):403-10. PMID: 27525324

Article Published Date : May 31, 2016

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Bisphenol Toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Bisphenol A

[+]

Vitamin C could remit isoflurane-induced apoptosis and relieve the decline in learning and memory ability of rats.Sep 30, 2016

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Pubmed Data : J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4):961-969. PMID: 28078842

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Pubmed Data : Int Wound J. 2015 Aug 20. Epub 2015 Aug 20. PMID: 26290474

Article Published Date : Aug 19, 2015

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents

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Vitamin C had a significant role in ameliorating the damage of testes induced by doxorubicin.Mar 31, 2017

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Pubmed Data : Nutr Cancer. 2011 ;63(7):1036-43. Epub 2011 Sep 2. PMID: 21888506

Article Published Date : Dec 31, 2010

Study Type : Animal Study

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Substances : Vitamin C, Vitamin K

Diseases : Lung Cancer, Lung Cancer: Metastatic

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Disease Regression, Dose Response

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Vitamin C inhibits the growth of human mammary tumor xenografts. Dec 01, 1991

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Pubmed Data : Am J Clin Nutr. 1991 Dec;54(6 Suppl):1274S-1280S. PMID: 1962582

Article Published Date : Dec 01, 1991

Study Type : Transgenic Animal Study

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Substances : Vitamin C

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

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Vitamin C inhibits the inflammation associated ROS that promotes gastric tumorigenesis.Mar 25, 2015

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Pubmed Data : Cancer Prev Res (Phila). 2015 Mar 26. Epub 2015 Mar 26. PMID: 25813526

Article Published Date : Mar 25, 2015

Study Type : Animal Study

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Substances : Vitamin C

Diseases : Gastric Cancer, Gastrointestinal Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Tumor, Anticarcinogenic Agents, Antioxidants, Chemopreventive

Additional Keywords : Risk Reduction

Problem Substances : Tamoxifen

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Vitamin C is a nutritional stimulator of autophagy.Aug 09, 2017

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Pubmed Data : Science. 2015 Nov 5. Epub 2015 Nov 5. PMID: 26541605

Article Published Date : Nov 04, 2015

Study Type : Animal Study

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Substances : Vitamin C

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Cytotoxic

Additional Keywords : Selective Cytotoxicity

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Vitamin C lowered the serum glucose and hesperidin reduced the DNA damage in a sucrose overload model. Apr 15, 2018

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Pubmed Data : An Acad Bras Cienc. 2018 Apr 16:0. Epub 2018 Apr 16. PMID: 29668805

Article Published Date : Apr 15, 2018

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Pubmed Data : Toxicol Ind Health. 2018 Jan 1:748233718775540. Epub 2018 Jan 1. PMID: 29848237

Pubmed Data : Mutat Res. 2012 Feb 6. Epub 2012 Feb 6. PMID: 22331007

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Pubmed Data : Vet Med Int. 2011 ;2011:945439. Epub 2011 Apr 27. PMID: 21647348

Pubmed Data : Int J Vitam Nutr Res. 1990;60(4):366-71. PMID: 2101829

Article Published Date : Jan 01, 1990

Study Type : Animal Study

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Substances : Vitamin C

Diseases : Ascites

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Vitamin C restores healthy aging in a mouse model for Werner syndrome.Dec 31, 2009

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When used before therapy vitamin C was able to decrease methotrexate induced testicular histological injuries.Nov 30, 2016

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Pubmed Data : Turk J Urol. 2016 Dec ;42(4):235-239. PMID: 27909615

Pharmacological Actions : Gastrointestinal Agents

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A review of the anti-atherosclerotic effects of vitamins D and E in suppression of atherogenesis.Dec 13, 2016

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Pubmed Data : J Cell Physiol. 2016 Dec 14. Epub 2016 Dec 14. PMID: 27966778

A review of the role vitamin C plays on inflammation. Feb 05, 2017

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Pubmed Data : Inflammopharmacology. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28168552

Article Published Date : Feb 05, 2017

Study Type : Review

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Substances : Vitamin C

Diseases : Cardiovascular Diseases, Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

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Aged garlic extract and other antioxidant nutritional supplements exhibit potentially therpeutic properties in sickle erythrocytes.Mar 01, 2001

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Pubmed Data : J Nutr. 2001 Mar ;131(3s):1085S-92S. PMID: 11238822

Article Published Date : Mar 01, 2001

Study Type : In Vitro Study

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Substances : Antioxidant formulas, Garlic, Vitamin C, Vitamin E

Diseases : Anemia: Sickle Cell

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

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Alpha lipoic acid and vitamin C prevent LDL oxidation and oxidant stress in endothelial cells. Feb 01, 2008

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Pubmed Data : Mol Cell Biochem. 2008 Feb;309(1-2):125-32. Epub 2007 Nov 16. PMID: 18026819

Article Published Date : Feb 01, 2008

Study Type : In Vitro Study

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Substances : Alpha-Lipoic Acid, Vitamin C

Diseases : Cholesterol: Oxidation, Endothelial Damage

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Antioxidant regeneration is significantly enhanced in these complexes.Apr 20, 2015

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Pubmed Data : Chem Commun (Camb). 2015 Apr 21 ;51(36):7713-6. PMID: 25851839

Article Published Date : Apr 20, 2015

Study Type : In Vitro Study

Additional Links

Substances : Quercetin, Vitamin C, Vitamin E

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Antioxidant Systems, Natural Substance Synergy

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Antioxidant vitamins C, E, β-carotene and B vitamins and related compounds possess the capability to emit solvated electrons.Mar 31, 2013

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Pubmed Data : Nutrition. 2013 Apr ;29(4):597-604. Epub 2013 Jan 8. PMID: 23306138

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Pubmed Data : Crit Care. 2015 ;19(1):418. Epub 2015 Nov 27. PMID: 26612352

Article Published Date : Dec 31, 2014

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Sepsis, Septic Shock, Vitamin C Deficiency

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

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Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs.Apr 30, 2011

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Pubmed Data : Cytotechnology. 2018 May 18. Epub 2018 May 18. PMID: 29777434

Article Published Date : May 17, 2018

Study Type : In Vitro Study

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Substances : Vitamin C

Additional Keywords : Mesenchymal Stem Cells

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Ascorbic acid prevents zinc oxide nanoparticle-induced intracellular oxidative stress and inflammatory responses.Dec 31, 2016

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Pubmed Data : Toxicol Ind Health. 2017 Jan 1:748233717707361. Epub 2017 Jan 1. PMID: 28854869

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Dose Response

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Combined use of doxycycline and vitamin C could represents a new synthetic-lethal metabolic strategy for eradicating CSCs.Sep 14, 2017

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Pubmed Data : Oncotarget. 2017 Sep 15 ;8(40):67269-67286. Epub 2017 Jun 9. PMID: 28978032

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Pubmed Data : Orthop Traumatol Surg Res. 2017 Mar 5. Epub 2017 Mar 5. PMID: 28274883

Article Published Date : Mar 04, 2017

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Bone Fractures, Complex Regional Pain Syndrome: Type I

Additional Keywords : Risk Reduction

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Deficiency of vitamin D and vitamin C could alter the pathogenesis of bronchial asthma.Dec 31, 2015

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Pubmed Data : Oncotarget. 2017 Jun 9. Epub 2017 Jun 9. PMID: 28622697

Article Published Date : Jun 08, 2017

Study Type : In Vitro Study

Additional Links

Substances : Berberine, Vitamin C

Diseases : Breast Cancer, Breast Cancer Stem Cells, Cancers: All

Pharmacological Actions : Antiproliferative

Additional Keywords : Cancer Stem Cells, Natural Substance/Drug Synergy

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Emerging evidence provides data in support of the administration of vitamin C in addition to standard therapy to ameliorate sepsis and septic shock.Sep 17, 2017

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Pubmed Data : J Crit Care. 2017 Sep 18 ;43:230-234. Epub 2017 Sep 18. PMID: 28934705

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Pubmed Data : J Photochem Photobiol B. 2016 Apr 9 ;161:266-272. Epub 2016 Apr 9. PMID: 27288656

Article Published Date : Apr 08, 2016

Study Type : In Vitro Study

Additional Links

Substances : Gold (nanoparticles), Vitamin C

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Bioenhancer

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Grifola frondosa and Vitamin C had a synergistic apoptotic effect on SMMC-7721 liver cancer cells. May 04, 2016

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Pubmed Data : Integr Cancer Ther. 2016 May 5. Epub 2016 May 5. PMID: 27151580

Article Published Date : May 04, 2016

Study Type : In Vitro Study

Additional Links

Substances : Maitake Mushroom, Vitamin C

Diseases : Liver Cancer

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation

Additional Keywords : Natural Substance Synergy

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Herbs provide protection against harmful UV radiation due to their antioxidant activity.Jul 01, 2011

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Pubmed Data : Nutr Cancer. 2018 May-Jun;70(4):684-696. Epub 2018 Apr 26. PMID: 29697268

Article Published Date : Apr 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C, Vitamin E: alpha tocopherol

Diseases : Chemotherapy-Induced Toxicity: Arsenic Trioxide

Pharmacological Actions : Chemoprotective Agents

Problem Substances : Arsenic Trioxide

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L-ascorbic acid exhibited an additive effect on cell proliferation in all gefitinib-sensitive and gefitinib-resistant cell lines.Jun 30, 2017

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Pubmed Data : Oncol Lett. 2017 Jul ;14(1):276-282. Epub 2017 May 2. PMID: 28693165

Article Published Date : Jun 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

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Limited vitamin C availability resulted in a functional type II cell but a cell more sensitive to oxidant-induced injury.Sep 30, 1997

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Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 1997 Oct 1 ;273(4):L782-L788. PMID: 29585842

Article Published Date : Sep 30, 1997

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Oxidative Stress, Vitamin C Deficiency

Pharmacological Actions : Antioxidants

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Problem Substances : Thimerosal

Adverse Pharmacological Actions : Immunotoxic

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Oral sodium bicarbonate and intravenous DHA may have the potential to blunt the aggressiveness of certain cancers.Sep 30, 2013

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Pubmed Data : Int J Biol Sci. 2016 ;12(9):1093-103. Epub 2016 Jul 22. PMID: 27570483

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Baicalein, Iodine, Luteolin, Rosmarinic acid, Vitamin C, Vitamin D

Diseases : Lyme Borreliosis, Lyme Disease

Pharmacological Actions : Antimicrobial

Additional Keywords : Natural Substance/Drug Synergy

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Potassium potentiated the anti-tumoral effects of vitamin C in breast cancer cells in vitro.May 31, 2016

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Pubmed Data : Oncol Lett. 2016 Jun ;11(6):4224-4234. Epub 2016 Apr 27. PMID: 27313770

Article Published Date : May 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Potassium, Vitamin C

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Natural Substance Synergy

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Resveratrol and ascorbic acid protected methylmercury induced cell death in primary cultures of cortical neurons.Jul 30, 2018

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Pubmed Data : Neurotoxicology. 2018 Jul 31. Epub 2018 Jul 31. PMID: 30075218

Pubmed Data : Toxicol In Vitro. 2009 Aug;23(5):763-71. Epub 2009 Apr 9. PMID: 20689415

Article Published Date : Aug 01, 2009

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Oxidative Stress, Surgery: All

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Salvianolic acid B, a compound found within red sage, and vitamin C work synergistically to enhance embyronic stem cell differentiation into cardiomyocytes.Oct 02, 2009

Storage of human corenea with anti-oxidative vitamins prior to transplantation may prolong the survival of corneal grafts. Jun 01, 2005

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Pubmed Data : Cell Tissue Res. 2005 Jun;320(3):465-75. Epub 2005 Apr 19. PMID: 15838641

Article Published Date : Jun 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C, Vitamin E

Diseases : Organ Transplantation: Cornea

Pharmacological Actions : Antioxidants, Apoptotic

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View the Evidence: 634 Abstracts with Vitamin C Research

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Lipoprotein(a) and vitamin C impair development of breast cancer tumors.Aug 31, 2016

Melatonin, ascorbic acid and β-carotene could protect against gastric damage induced by intensive stress.Oct 11, 2015

Melatonin, minocycline and ascorbic acid have an antiviral effect involving their anti-oxidant properties, and suggesting a potential use of these compounds for human VEE virus infection.Jul 09, 2015

Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression.Aug 17, 2017

Multiple myeloma tumor cells are selectively killed by pharmacologically-dosed ascorbic acid.Mar 31, 2017

Muskmelon, watermelon and mango fruit may have an ameliorative effect on atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia in rats.Jan 01, 2008

Natural substances could be used to slow down dementia. Jul 31, 2017

Oral administration of vitamin C and vitamin E significantly reduced the blood lead concentration, ameliorates the hepatic damage and reduces oxidative stress.Mar 31, 2012

Oral antioxidant supplementation with vitamin C and vitamin E counteract the negative effects of female aging on oocyte quantity and quality in the mouse.Mar 01, 2002

Oral intake of vitamin C prevents acute pulmonary oxidative stress and inflammation caused by zinc oxide nanoparticles.Dec 31, 2014

Parenteral Vitamin C has the ability to improve the outcome of sepsis and sepsis-induced multiple organ dysfunction syndrome.Dec 31, 2016

Pharmacologic ascorbate is a pro-oxidant that eliminates influenza virus in the lung.Apr 30, 2014

Pharmacologic ascorbate was superior or equivalent to dacarbazine as an antitumor agent. Jun 24, 2015

Pharmacological concentrations of ascorbate exhibit antitumoral effects. Jul 01, 2009

Pre and post treatment with ascorbic acid and α-tocopherol reduced oxidative stress induced by brain injury and effectively reduced mortality rate in rats.Jun 30, 2013

Pre-treatment with vitamin C may be effective in protecting liver tissue against dexmedetomidine can induced hepatic injury and oxidative stress.Dec 31, 2015

Quercetin and vitamin C mitigate cobalt chloride-induced hypertension. Jun 09, 2016

Quercetin in combination with vitamins (C and E) improves oxidative stress and renal injury in cadmium intoxicated rats.Nov 01, 2010

Red ginseng and vitamin C enhanced the activation of immune cells like T and NK cells, and repressed the progress of viral lytic cycle.Feb 29, 2016

Resistance to cetuximab in human colon cancer patients with a mutant KRAS can be bypassed by L-ascorbic acid in an SVCT-2-dependent manner.Mar 21, 2016

Selenium and vitamin C may be a promising therapeutic strategy for barium induced heart injury.Dec 08, 2016

Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.Feb 07, 2018

Severe liver damage induced by inflammation could be prevented by sufficient supplementation with vitamin C.Dec 09, 2013

Supplementation with a nutrient mixture in female mice demonstrated a potent inhibition of tumor growth and enhancement of extracellular matrix proteins.Aug 31, 2015

Supplementation with Vitamin C and E improve lung repair aftery emphysema induced by long-term cigarette smoke exposure in mice. Sep 01, 2008

The co-administration of vitamin E during chelation treatment with DMSA or MiADMSA could be recommended for achieving optimum effects of chelation therapy.Jun 14, 2003

The combination of α-tocopherol acetate and ascorbic acid produced radioprotective effects and enhanced apoptosis in irradiated cells.Jul 06, 2016

The combined treatment was effective in decreasing intracellular ROS and lipid peroxidation in cardiac tissue.Jul 08, 2018

The combined treatments with vitamins has a protective effect on forced swimming-induced oxidative stress.Dec 31, 2015

The present results imply that ascorbic acid treatment during pregnancy may protect against lead mediated developmental impairments in the cerebellum.Feb 16, 2018

The present study indicates that vitamin C may be a novel therapeutic method for patients with advanced tumors.Oct 31, 2016

The protective effects of vitamin C on influenza virus-caused pneumonia might be related to its inhibition of CORT synthesis.Dec 31, 2014

The results indicate the potential anxiolytic effect of ascorbic acid.Feb 12, 2018

The results obtained in vivo after treatment with AA showed a large reduction in the rate of tumor growth.Dec 31, 2011

The significant radioprotective effect of vitamin C at doses used in this study opens new horizons in developing non-toxic, cost effective, easily available radioprotectors.May 31, 2015

These findings indicate a synergistic protective effect of ferulic acid and ascorbic acid on lipid peroxidation and antioxidant defense system during ISO-induced myocardial infarction.Jan 31, 2006

These findings suggest that vitamin C deficiency could induce spatial memory deficits.Jun 28, 2018

These results offer support for vitamin C and its potential use as protective treatment in cases of chronic paracetamol overdose.Aug 02, 2017

These results suggest that a long-term high-dose intake of VC is effective in the maintenance of immune cells.Feb 27, 2015

These results support the suppression of the hypoxic response by ascorbate as a plausible mechanism of action of its anti-tumour activity.Aug 23, 2016

This animal study found that vitamin C depletion increased the growth and metastasis of melanoma cells. Nov 30, 2011

This in vivo study provides novel data that vitamin C improves cardiac structure and function in doxorubicin-induced cardiomyopathySep 30, 2017

This study demonstrated the results of interactions between ascorbic acid and tramadol or morphine.Jul 31, 2014

This study demonstrates the impact of suboptimal levels of ascorbate on longevity and the metabolic profile of a mouse model.Feb 19, 2016

This study showed that vitamin C improved the effect of ASC transplantation on tendonitis by inducing a better stem cell niche.Apr 30, 2017

This study shows direct therapeutic benefits of ascorbic acid on corneal epithelial wound healing.Mar 08, 2017

Treatment with ascorbic acid and α-tocopherol modulates oxidative-stress markers in the spinal cord of rats with neuropathic pain.Feb 28, 2018

Treatment with berberine prevents the changes in oxidative stress and ChE activity, and consequently memory impairment in ethanol treated rats.Jul 05, 2015

Vitamin A, C and E reduce azo-dye binding protein in liver of rats.Apr 01, 2010

Vitamin C administration could be used to reduce acrylamide-induced neurotoxicity.Dec 31, 2017

Vitamin C administration has a possibility to prevent hippocampal neuronal damage caused by neonatal and juvenile hypothyroidism in rats.Nov 23, 2017

Vitamin C ameliorates aflatoxin-induced adverse effects in rabbits.Mar 01, 2003

Vitamin C ameliorates alterations in thyroid hormones concentrations induced by subchronic coadministration of chlorpyrifos and lead in wistar rats.Jan 01, 2011

Vitamin C ameliorates aluminium-induced deterioration in reproductive performance and seminal plasma biochemistry of male rabbits. Nov 05, 2005

Vitamin C ameliorates fluoride-induced embryotoxicity in pregnant rats.Dec 01, 2001

Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female rats.Jul 01, 2009

Vitamin C and Baicalin inhibits tumor growth by enhancing the antioxidant capacity in vivo.Aug 31, 2015

Vitamin C and E protects against against lead-induced genotoxicity and sperm abnormalities in mice. Jan 01, 2004

Vitamin C and E reduce the endocrine disruptive effects of polychlorinated biphenyl on testicular function. Apr 11, 2007

Vitamin C and hyaluronic acid had therapeutic effects on tendon healing.Feb 28, 2018

Vitamin C and Nigella sativa oil proved to have synergistic nephro-protective effect.Sep 30, 2012

Vitamin C and rosemary leaf extract showed ameliorative potential to reduce tissue accumulation of cadmium and associated oxidative stress.Oct 31, 2015

Vitamin C and silymarin supplements ameliorate lead toxicity on rat liver. Apr 01, 2009

Vitamin C and vitamin E exert significant protective effects from 50 Hz ELF-EMF radiation.Dec 31, 2016

Vitamin C and vitamin E might play an important role in reducing oxidative stress and kidney damage induced by diclofenac sodium.Sep 21, 2016

Vitamin C and vitamin E protect the rat testes from cadmium-induced reactive oxygen species.Feb 29, 2004

Vitamin C and vitamin E supplementation alleviates oxidative stress induced by dexamethasone and improves fertility of breeder roosters.Jul 31, 2016

Vitamin C at high concentrations induces cytotoxicity in malignant melanoma but promotes tumor growth at low concentrations.Mar 29, 2017

Vitamin C at lower doses showed anti-oxidant effect and at higher dose resulted in pro-oxidant effects in colchicine induced Alzheimer's disease.Sep 23, 2016

Vitamin C attenuates the mutagenicity of the antiamebic drug diiodohydroxyquinoline. Mar 01, 1989

Vitamin C can ameliorate the toxic effect of methotrexate in liver and kidney tissues of rat.Jun 28, 2017

Vitamin C can be effective on some of the sperm parameters and can reduce cyclophosphamide-induced complications in animal model.Mar 31, 2017

View the Evidence:
634 Abstracts with Vitamin C Research