Vitamin D

Vitamin D

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View the Evidence: Substances

Alzheimer's disease cases have lower serum vitamin D concentrations than matched controls.

Pubmed Data : J Alzheimers Dis. 2012 Oct 5. Epub 2012 Oct 5. PMID: 23042216
Article Published Date : Oct 04, 2012
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Alzheimer's Disease : CK(826) : AC(160), Vitamin D Deficiency : CK(495) : AC(45)
Additional Keywords : neurosteroid hormone

Being in the lowest quartile of vitamin D levels is associated with a 26% increased rate of all-cause mortality

Pubmed Data : Arch Intern Med. 2008 Aug 11;168(15):1629-37. PMID: 18695076
Article Published Date : Aug 11, 2008
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Cardiac Mortality : CK(703) : AC(67), Mortality: All-Cause : CK(644) : AC(55), Vitamin D Deficiency : CK(495) : AC(45)

Blood 25-hydroxyvitamin D concentration is inversely associated with hypertension.

Pubmed Data : J Hypertens. 2011 Apr;29(4):636-45. PMID: 21191311
Article Published Date : Apr 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Hypertension : CK(2783) : AC(271)

Doubling global vitamin D levels could significantly reduce mortality.

Pubmed Data : Eur J Clin Nutr. 2011 Jul 6. Epub 2011 Jul 6. PMID: 21731036
Article Published Date : Jul 06, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : African-American Specific Deficiencies/Diseases : CK(200) : AC(19), Cardiac Mortality : CK(703) : AC(67), Cardiovascular Diseases : CK(5138) : AC(641), Mortality: All-Cause : CK(644) : AC(55), Respiratory Diseases : CK(174) : AC(29), Tuberculosis : CK(255) : AC(44), Vitamin D Deficiency : CK(495) : AC(45)
Therapeutic Actions : Sunlight exposure : CK(432) : AC(39)

Higher intakes of vitamin D, protein and potassium are significantly associated with decreased risks of onset of overactive bladder.

Pubmed Data : Neurourol Urodyn. 2004;23(3):204-10. PMID: 15098215
Article Published Date : Jan 01, 2004
Study Type : Meta Analysis
Additional Links
Substances : Potassium : CK(99) : AC(15), Protein Supplement : CK(73) : AC(7), Vitamin D : CK(1682) : AC(238)
Diseases : Overactive Bladder : CK(105) : AC(13)

Higher maternal milk and vitamin D intake during pregnancy may be associated with a lower risk of developing MS in offspring.

Pubmed Data : Ann Neurol. 2011 Jul ;70(1):30-40. PMID: 21786297
Article Published Date : Jul 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Cow Milk : CK(20) : AC(3), Vitamin D : CK(1682) : AC(238)
Diseases : Multiple Sclerosis: Prevention : CK(21) : AC(1), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31)
Therapeutic Actions : Breastfeeding : CK(708) : AC(67)

Higher vitamin D levels are associated with a decreased risk of pelvic floor disorders in women.

Pubmed Data : Obstet Gynecol. 2010 Apr;115(4):795-803. PMID: 20308841
Article Published Date : Apr 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Pelvic Floor Dysfunction (PFD) : CK(50) : AC(4), Vitamin D Deficiency : CK(495) : AC(45)

Low concentrations of serum 25-hydroxyvitamin D associated with increased risk for chronic bronchitis among US adults.

Pubmed Data : Br J Nutr. 2011 Sep 8:1-7. Epub 2011 Sep 8. PMID: 21899806
Article Published Date : Sep 08, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Bronchitis : CK(73) : AC(7), Vitamin D Deficiency : CK(495) : AC(45)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.

Pubmed Data : Anticancer Res. 2012 Jan ;32(1):223-36. PMID: 22213311
Article Published Date : Jan 01, 2012
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Bladder Cancer : CK(186) : AC(60), Breast Cancer : CK(2354) : AC(621), Cervical Cancer : CK(363) : AC(69), Colon Cancer : CK(895) : AC(233), Colorectal Cancer : CK(877) : AC(321), Endometrial Cancer : CK(269) : AC(45), Esophageal Cancer : CK(328) : AC(55), Hodgkin Lymphoma : CK(53) : AC(7), Lung Cancer : CK(496) : AC(198), Non-Hodgkin Lymphoma : CK(525) : AC(67), Ovarian Cancer : CK(154) : AC(58), Pancreatic Cancer : CK(530) : AC(168), Renal Cancer : CK(25) : AC(4), Vulvar Cancer : CK(52) : AC(4)
Therapeutic Actions : Sunlight exposure : CK(432) : AC(39)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

There is a consistent inverse relationship between serum 25-hydroxyvitamin D levels and colorectal cancer was found.

Pubmed Data : Int J Cancer. 2011 Mar 15 ;128(6):1414-24. PMID: 20473927
Article Published Date : Mar 15, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Colorectal Cancer: Prevention : CK(52) : AC(1), Vitamin D Deficiency : CK(495) : AC(45)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Vitamin D exposure from both sun and diet are correlated with breast cancer risk.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2011 Jan;20(1):187-98. Epub 2010 Dec 2. PMID: 21127286
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Breast Cancer: Prevention : CK(525) : AC(73)
Therapeutic Actions : Sunlight exposure : CK(432) : AC(39)

Vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons.

Pubmed Data : JAMA. 2005 May 11;293(18):2257-64. PMID: 15886381
Article Published Date : May 11, 2005
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Bone Fractures : CK(1610) : AC(69), Hip Fracture : CK(1724) : AC(21)

Vitamin D supplementation may reduce systolic blood pressure.

Pubmed Data : South Med J. 2010 Aug;103(8):729-37. PMID: 20622727
Article Published Date : Aug 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Hypertension : CK(2783) : AC(271)

Vitamin D supplementation reduces mortality in adults.

Pubmed Data : Cochrane Database Syst Rev. 2011(7):CD007470. Epub 2011 Jul 6. PMID: 21735411
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Elderly: Age Specific Diseases : CK(442) : AC(37), Mortality: All-Cause : CK(644) : AC(55)

Vitamin D, cognition, and dementia: a systematic review and meta-analysis.

Pubmed Data : Neurology. 2012 Sep 25 ;79(13):1397-405. PMID: 23008220
Article Published Date : Sep 24, 2012
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Alzheimer's Disease : CK(826) : AC(160), Dementia : CK(225) : AC(31), Dementia: Alzheimer Type : CK(1) : AC(1), Vitamin D Deficiency : CK(495) : AC(45)

"Modest reversal of metabolic syndrome manifestations with vitamin D status correction"

Pubmed Data : Metabolism. 2012 May ;61(5):661-6. Epub 2011 Nov 8. PMID: 22075268
Article Published Date : May 01, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Metabolic Syndrome X : CK(645) : AC(122)

"Vitamin D deficiency is a predictor of reduced survival in patients with heart failure; vitamin D supplementation improves outcome."

Pubmed Data : Eur J Heart Fail. 2012 Feb 3. Epub 2012 Feb 3. PMID: 22308011
Article Published Date : Feb 03, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Congestive Heart Failure : CK(256) : AC(33), Heart Failure : CK(711) : AC(97)

4,000 i.u of vitamin D supplementation during pregnancy is considered safe and effective in achieving sufficiency in all women and their neonates regardless of race

Pubmed Data : J Bone Miner Res. 2011 Oct ;26(10):2341-57. PMID: 21706518
Article Published Date : Oct 01, 2011
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Prenatal Nutrition : CK(180) : AC(25), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Vitamin D Deficiency : CK(495) : AC(45)
Additional Keywords : vitamin d dosage

A combination of quercetin, ascorbyl palmitate and vitamin D appears to safely offer relief of symptomatic diabetic neuropathy.

Pubmed Data : J Diabetes Complications. 2005 Sep-Oct;19(5):247-53. PMID: 16112498
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Ascorbyl Palmitate : CK(10) : AC(1), Quercetin : CK(318) : AC(136), Vitamin C : CK(1274) : AC(238), Vitamin D : CK(1682) : AC(238)
Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Diabetic Neuropathies : CK(203) : AC(32), Peripheral Neuropathies : CK(394) : AC(31)
Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208)

A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women.

Pubmed Data : Panminerva Med. 2010 Jun;52(2 Suppl 1):49-54. PMID: 20657535
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Astaxanthin : CK(353) : AC(117), Bioflavonoids : CK(21) : AC(3), Calcium : CK(232) : AC(35), Lycopene : CK(194) : AC(38), Vitamin D : CK(1682) : AC(238)
Diseases : Menopausal Syndrome : CK(171) : AC(27)

Adequate vitamin D stores may prevent breast cancer development.

Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Jun;2(6):598-604. Epub 2009 May 26. PMID: 19470790
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Breast Cancer: Prevention : CK(525) : AC(73)

Background exposure to some organochlorine pesticides appears to lead to vitamin D deficiency in human.

Pubmed Data : PLoS One. 2012 ;7(1):e30093. Epub 2012 Jan 25. PMID: 22295072
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Pesticide-Induced Toxicity: Organochlorines : CK(32) : AC(4), Vitamin D Deficiency : CK(495) : AC(45)
Problem Substances : Organochlorine pesticides : CK(260) : AC(30)

Both high and low concentrations of plasma 25(OH)D are associated with elevated risks of overall and cancer mortality. Low concentrations are associated with cardiovascular mortality.

Pubmed Data : Am J Clin Nutr. 2010 Oct;92(4):841-8. Epub 2010 Aug 18. PMID: 20720256
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Cardiac Mortality : CK(703) : AC(67), Cardiovascular Diseases : CK(5138) : AC(641), Elderly: Age Specific Diseases : CK(442) : AC(37), Hypertension : CK(2783) : AC(271), Mortality: All-Cause : CK(644) : AC(55)
Additional Keywords : Too Much Vitamin D : CK(10) : AC(1)

Breastfed infants in winter who did not receive vitamin D supplementation were the most severely vitamin D deficient (78%).

Pubmed Data : Arch Pediatr Adolesc Med. 2008 Jun;162(6):513-9. PMID: 18524740
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Breastfeeding: Nutritional Deficiencies : CK(42) : AC(5), Infant Nutrition : CK(70) : AC(13), Lactation Disorders : CK(132) : AC(16), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Vitamin D Deficiency : CK(495) : AC(45)

Cord-blood levels of 25(OH)D has an inverse associations with risk of respiratory infection and childhood wheezing.

Pubmed Data : Pediatrics. 2010 Dec 27. Epub 2010 Dec 27. PMID: 21187313
Article Published Date : Dec 27, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Infant Infections : CK(420) : AC(45), Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41), Respiratory Infections: Infants & Children : CK(80) : AC(8)

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