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Vitamin K

Vitamin K

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Article Count - 65
Cumulative Knowledge - 562

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Quick Summary: Current access displays 2 out of 56 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Osteoporosis	230	25	Log in \| Sign up
Bone Fractures	106	9	Log in \| Sign up

Quick Summary: Current access displays 2 out of 14 associated Pharmacological Actions

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Cardioprotective	40	2	Log in \| Sign up
Anticarcinogenic Agents	10	1	Log in \| Sign up

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View the Evidence: Substances

High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women.

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Pubmed Data : Nutr Res. 2009 Apr;29(4):221-8. PMID: 19410972

Article Published Date : Apr 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Vitamin K : CK(550) : AC(65), Vitamin K2 : CK(277) : AC(32)

Diseases : Bone Fractures : CK(1610) : AC(69), Osteoporosis : CK(1171) : AC(205), Postmenopausal Disorders : CK(285) : AC(35)

Infant vitamin K injections are associated with an increased risk for acute lymphoblastic leukaemia.

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Pubmed Data : BMJ. 1998 Jan 17;316(7126):189-93. PMID: 9468683

Article Published Date : Jan 17, 1998

Study Type : Meta Analysis

Additional Links

Substances : Vitamin K : CK(550) : AC(65)

Diseases : Acute lymphoblastic leukemia (ALL) : CK(96) : AC(29), Cancers: Pediatric : CK(95) : AC(10)

Anti Therapeutic Actions : Vitamin K injections : CK(23) : AC(2)

Vitamin K1 and K2 exhibit anti-fracture activity.

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Pubmed Data : Clin Calcium. 2009 Dec;19(12):1805-14. PMID: 19949272

Article Published Date : Dec 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Vitamin K2 : CK(277) : AC(32)

Diseases : Bone Fractures : CK(1610) : AC(69), Osteoporosis : CK(1171) : AC(205)

A high vitamin K2 (menaquinone) intake reduces the incidence of coronary heart disease.

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2009 Sep;19(7):504-10. Epub 2009 Jan 28. PMID: 19179058

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin K2 : CK(277) : AC(32), Vitamin K2: (MK-8) : CK(10) : AC(1), Vitamin K2: (MK-9) : CK(10) : AC(1), Vitamin K2: Menaquinone-7 : CK(88) : AC(14)

Diseases : Coronary Artery Disease : CK(1305) : AC(136)

A vitamin K2 preparation inhibits the development of liver cancer in patients with type C cirrhosis.

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Pubmed Data : Hepatogastroenterology. 2010 Sep-Oct;57(102-103):1264-7. PMID: 21410069

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Substances : Menatetrenone : CK(10) : AC(1), Vitamin K2 : CK(277) : AC(32), Vitamin K2: Menaquinones (MK-4-14) : CK(149) : AC(19)

Diseases : Liver Cancer : CK(1641) : AC(266), Liver Cirrhosis : CK(216) : AC(32)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Hepatoprotective : CK(557) : AC(272)

Adding vitamin K(2) to vitamin D(3) with calcium reduced the lifetime probability ofat least one fracture by 25%, increased discounted survival by 0.7 quality-adjusted life-years (QALYs).

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Pubmed Data : Osteoporos Int. 2012 Mar 8. Epub 2012 Mar 8. PMID: 22398856

Article Published Date : Mar 08, 2012

Study Type : Human Study

Additional Links

Substances : Vitamin K2 : CK(277) : AC(32)

Diseases : Bone Fractures : CK(1610) : AC(69)

Arnica appears effective in reducing experimentally induced bruising.

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Pubmed Data : Br J Dermatol. 2010 Sep;163(3):557-63. PMID: 20412090

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Substances : Vitamin K : CK(550) : AC(65)

Diseases : Bruising : CK(30) : AC(3)

Collard greens are a rich and bioavailable source of vitamin K.

Click here to read the entire abstract

Pubmed Data : World J Gastroenterol. 2010 Apr 7;16(13):1622-30. PMID: 14767874

Article Published Date : Apr 07, 2010

Study Type : Human Study

Additional Links

Substances : Vitamin K : CK(550) : AC(65)

Diseases : Vitamin K Deficiency : CK(22) : AC(3)

Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease, cardiac mortality, aortic calcification and all-cause mortality.

Click here to read the entire abstract

Pubmed Data : J Nutr. 2004 Nov;134(11):3100-5. PMID: 15514282

Article Published Date : Nov 01, 2004

Study Type : Human Study

Additional Links

Substances : Vitamin K : CK(550) : AC(65), Vitamin K2 : CK(277) : AC(32), Vitamin K2: Menaquinone-7 : CK(88) : AC(14)

Diseases : Aortic Calcification : CK(180) : AC(7), Arteriosclerosis : CK(2154) : AC(123), Cardiac Mortality : CK(703) : AC(67), Coronary Artery Disease : CK(1305) : AC(136), Mortality: All-Cause : CK(644) : AC(55), Myocardial Infarction : CK(2632) : AC(117)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Dietary vitamin K2 supplement improves bone status after lung and heart transplantation.

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Pubmed Data : Transplantation. 2010 Feb 27;89(4):458-64. PMID: 20177349

Article Published Date : Feb 27, 2010

Study Type : Human Study

Additional Links

Substances : Vitamin K2 : CK(277) : AC(32), Vitamin K2: Menaquinone-7 : CK(88) : AC(14)

Diseases : Organ Transplantation : CK(50) : AC(17), Organ Transplantation: Heart : CK(34) : AC(5), Organ Transplantation: Lung : CK(10) : AC(1), Osteoporosis : CK(1171) : AC(205)

High dietary intake of vitamin K rich foods is associated with a lower risk of coronary artery disease.

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2005 Feb;59(2):196-204. PMID: 15454972

Article Published Date : Feb 01, 2005

Study Type : Human Study

Additional Links

Substances : Vitamin K : CK(550) : AC(65)

Diseases : Coronary Artery Disease : CK(1305) : AC(136)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

High dietary menaquinone (Vitamin K2) intake is associated with reduced coronary calcification.

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 2009 Apr;203(2):489-93. Epub 2008 Jul 19. PMID: 18722618

Article Published Date : Apr 01, 2009

Study Type : Human Study

Additional Links

Substances : Menaquinone : CK(20) : AC(2), Vitamin K2 : CK(277) : AC(32)

Diseases : Arterial Calcification : CK(154) : AC(25), Cardiovascular Diseases : CK(5138) : AC(641), Coronary Artery Disease : CK(1305) : AC(136)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

High dose vitamin K is efficacious in correcting vitamin K deficiency in cystic fibrosis.

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Pubmed Data : J Cyst Fibros. 2008 Sep;7(5):457-9. Epub 2008 May 29. PMID: 18511355

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin K : CK(550) : AC(65)

Diseases : Cystic Fibrosis : CK(703) : AC(77)

Additional Keywords : Pancreatic Insufficiency : CK(10) : AC(1)

Hop rho iso-alpha acids, berberine, vitamin D(3) and vitamin K (1) favorably impact biomarkers of bone turnover in postmenopausal women.

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Pubmed Data : J Bone Miner Metab. 2009 Dec 19. Epub 2009 Dec 19. PMID: 20024591

Article Published Date : Dec 19, 2009

Study Type : Human Study

Additional Links

Substances : Berberine : CK(156) : AC(75), Hops : CK(51) : AC(20), Vitamin D : CK(1682) : AC(238), Vitamin K : CK(550) : AC(65)

Diseases : Osteoporosis : CK(1171) : AC(205)

Intake of fermented soybean (natto) increases circulating vitamin K2 and osteocalcin (a marker for bone formation) in normal individuals.

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Pubmed Data : J Bone Miner Metab. 2000;18(4):216-22. PMID: 10874601

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Natto : CK(121) : AC(21), Vitamin K : CK(550) : AC(65)

Diseases : Osteoporosis : CK(1171) : AC(205)

Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Levels of menaquinone-7 and vitamin D are lower in those wtih hip fracture, indicating they may have a role in fracture prevention.

Click here to read the entire abstract

Pubmed Data : Asia Pac J Clin Nutr. 2011;20(1):56-61. PMID: 21393111

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Substances : Vitamin D : CK(1682) : AC(238), Vitamin K2: Menaquinone-7 : CK(88) : AC(14)

Diseases : Hip Fracture : CK(1724) : AC(21)

Low levels of vitamin D and K are highly prevalent and independent of overall malnutrition in the institutionalized elderly.

Click here to read the entire abstract

Pubmed Data : Bioorg Med Chem. 2010 Apr 15;18(8):2964-75. Epub 2010 Mar 6. PMID: 20199987

Article Published Date : Apr 15, 2010

Study Type : Human Study

Additional Links

Substances : Menaquinone : CK(20) : AC(2), Vitamin K : CK(550) : AC(65)

Diseases : Elderly: Age Specific Diseases : CK(442) : AC(37), Vitamin D Deficiency : CK(495) : AC(45), Vitamin K Deficiency : CK(22) : AC(3)

Low vitamin K status is associated with abnormal cartilage, bone mineralizations and osteoarthritis in the hand and knee.

Click here to read the entire abstract

Pubmed Data : Arthritis Rheum. 2006 Apr;54(4):1255-61. PMID: 16572460

Article Published Date : Apr 01, 2006

Study Type : Human Study

Additional Links

Substances : Vitamin K : CK(550) : AC(65)

Diseases : Bone Spur : CK(12) : AC(2), Osteoarthritis : CK(615) : AC(91), Osteoarthritis: Knee : CK(357) : AC(38), Osteophyte : CK(12) : AC(2)

Menaquinone-7 (vitamin K2) supplementation increases osteocalcin carboxylation associated with improved bone quality.

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2009 Oct;102(8):1171-8. Epub 2009 May 19. PMID: 19450370

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin K2: Menaquinone-7 : CK(88) : AC(14)

Diseases : Bone Fractures : CK(1610) : AC(69), Osteoporosis : CK(1171) : AC(205)

Natto, a rich source of vitamin K2, promotes bone formation in premenopausal women.

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2004 Apr;50(2):114-20. PMID: 15242015

Article Published Date : Apr 01, 2004

Study Type : Human Study

Additional Links

Substances : Natto : CK(121) : AC(21), Vitamin K : CK(550) : AC(65)

Diseases : Osteoporosis : CK(1171) : AC(205)

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