Borderline Personality Disorder https://greenmedinfo.com/taxonomy/term/1038/all en Alchemy, homeopathy and the treatment of borderline cases. https://greenmedinfo.com/article/alchemy-homeopathy-and-treatment-borderline-cases PMID:  J Anal Psychol. 1996 Jul ;41(3):369-86. PMID: 8760996 Abstract Title:  Alchemy, homeopathy and the treatment of borderline cases. Abstract:  Homeopathy is presented as a modality of potential usefulness in the treatment of borderline patients refractory to psychoanalytic work. In these instances a minimally adequate centre of consciousness did not solidify from the identity with the psychoid stratum. In the view of Alchemy, this failure of the mind to separate from the unio naturalis or massa confusa could be remedied by a medicamentum spagyricum, an archtypal essence acting according to the simile principle, which was to be extracted from various substances. Homeopathy is described as a modern, clinically effective modification of the alchemistic method. Two cases example are given for illustration. <p><a href="https://greenmedinfo.com/article/alchemy-homeopathy-and-treatment-borderline-cases" target="_blank">read more</a></p> https://greenmedinfo.com/article/alchemy-homeopathy-and-treatment-borderline-cases#comments Borderline Personality Disorder Homeopathic Medicine: All Human: Case Report Sun, 04 Feb 2024 19:10:06 +0000 greenmedinfo 287710 at https://greenmedinfo.com Art psychotherapy in a consumer diagnosed with borderline personality disorder. https://greenmedinfo.com/article/art-psychotherapy-consumer-diagnosed-borderline-personality-disorder PMID:  Int J Ment Health Nurs. 2009 Jun ;18(3):164-72. PMID: 19490226 Abstract Title:  Art psychotherapy in a consumer diagnosed with borderline personality disorder: a case study. Abstract:  This case study reviews 11 sessions of art psychotherapy with a consumer diagnosed with having borderline personality disorder. A consumer who reported difficulty in communicating her lived trauma verbally and engaged in self-harming behaviour was offered individual art therapy sessions following a consultation between an art therapy student and clinical nurse consultant in an attempt to understand her experiences and to collaboratively engage her. Notes were taken after each session by the art therapy student, reflecting conversations with this consumer while they were engaged in art making, which were subsequently explored within formal clinical supervision sessions with a mental health nurse consultant. An art portfolio is reproduced. It illustrates the expressive power of image creation. The key features of the images were that of lived trauma, the externalization of thoughts and feelings, and intense emotional expression. The results of this chronological art portfolio case study indicated therapeutic benefits from the intervention for this consumer. Further investigations of this type of intervention are warranted within the mental health setting. <p><a href="https://greenmedinfo.com/article/art-psychotherapy-consumer-diagnosed-borderline-personality-disorder" target="_blank">read more</a></p> https://greenmedinfo.com/article/art-psychotherapy-consumer-diagnosed-borderline-personality-disorder#comments Borderline Personality Disorder Art Therapy Human: Case Report Sun, 04 Feb 2024 17:42:47 +0000 greenmedinfo 287708 at https://greenmedinfo.com Ayahuasca therapy could be of value in to individuals with borderline personality disorder. https://greenmedinfo.com/article/ayahuasca-therapy-could-be-value-individuals-borderline-personality-disorder PMID:  Psychopharmacology (Berl). 2018 Nov 7. Epub 2018 Nov 7. PMID: 30406413 Abstract Title:  Ayahuasca improves emotion dysregulation in a community sample and in individuals with borderline-like traits. Abstract:  BACKGROUND: Research suggests that mindfulness-based interventions may improve mindfulness-related capacities (e.g., decentering, non-judging, and non-reacting) and emotion regulation. Previously, our group reported that ayahuasca could be a potential analogue of mindfulness practice. The main aim of the current study was to examine the effects of ayahuasca on emotional regulation and mindfulness-related capacities. Secondarily, we sought to explore the effects of ayahuasca on individuals with borderline personality disorder (BPD) traits.METHOD: This is an observational study of 45 volunteers who participated in an ayahuasca session. The volunteers completed various self-report instruments designed to measure emotional dysregulation (Difficulties in Emotion Regulation Scale (DERS)) and mindfulness traits (Five Facet Mindfulness Questionnaire (FFMQ)-Short Form and Experiences Questionnaire (EQ)) prior to and 24 h after the ayahuasca session. The volunteers were divided into two subgroups based on their score on the McLean Screening Instrument for BPD (MSI-BPD). Twelve participants were grouped into the BPD-like traits subgroup while the rest of them were included in the non-BPD-like subgroup. We performed within-subjects and between-group analyses.RESULTS: Overall, the participants showed significant improvements on the FFMQ subscales observing, acting with awareness, non-judging, and non-reacting and also significantly improved on decentering (EQ scale) and on the DERS subscales emotional non-acceptance, emotional interference, and lack of control. The BPD-like subgroup also showed significant improvements on the DERS subscales emotional interference and lack of control but not in mindfulness capacities.CONCLUSIONS: These findings suggest a potential therapeutic effect for ayahuasca in emotion regulation and mindfulness capacities (including decentering, acceptance, awareness, and sensitivity to meditation practice). Based on these results, we believe that ayahuasca therapy could be of value in clinical populations, such as individuals with BPD, affected by emotion dysregulation. <p><a href="https://greenmedinfo.com/article/ayahuasca-therapy-could-be-value-individuals-borderline-personality-disorder" target="_blank">read more</a></p> https://greenmedinfo.com/article/ayahuasca-therapy-could-be-value-individuals-borderline-personality-disorder#comments Ayahuasca Borderline Personality Disorder Human Study Fri, 30 Nov 2018 01:29:41 +0000 greenmedinfo 174824 at https://greenmedinfo.com Beyond borderline personality disorder: the mindful brain. https://greenmedinfo.com/article/beyond-borderline-personality-disorder-mindful-brain PMID:  Soc Work. 2014 Oct ;59(4):297-302. PMID: 25365830 Abstract Title:  Beyond borderline personality disorder: the mindful brain. Abstract:  Numerous studies have showed an improvement in symptoms characteristic of borderline personality disorder (BPD) when mindfulness-based interventions were integrated into the daily lives of individuals with BPD. Although these studies have examined the etiology and diagnostic prognosis of BPD, and have discussed the use of mindfulness-based treatments, few researchers have attempted to interpret the neuroscientific findings, which have showed an increase in gray matter in key areas of the brain in clients with BPD who engaged in mindfulness practice. Some clients who had originally met a minimum of five of the DSM-IV-TR diagnostic criteria for BPD no longer did so upon engaging in mindfulness-based treatment. This article highlights the efficacy of mindfulness-based interventions with an emphasis on meditation, which leads to overall better psychological functioning in clients with BPD in three key areas: impulsivity, emotional irregularity, and relationship instability. <p><a href="https://greenmedinfo.com/article/beyond-borderline-personality-disorder-mindful-brain" target="_blank">read more</a></p> https://greenmedinfo.com/article/beyond-borderline-personality-disorder-mindful-brain#comments Borderline Personality Disorder Mindfullness Training Review Sun, 04 Feb 2024 17:38:11 +0000 greenmedinfo 287702 at https://greenmedinfo.com Brief, intensive EMDR therapy for borderline personality disorder. https://greenmedinfo.com/article/brief-intensive-emdr-therapy-borderline-personality-disorder PMID:  Front Psychiatry. 2023 ;14:1283145. Epub 2023 Dec 15. PMID: 38188059 Abstract Title:  Case report: Brief, intensive EMDR therapy for borderline personality disorder: results of two case studies with one year follow-up. Abstract:  BACKGROUND: Exposure to adverse childhood events plays an important role in the development of borderline personality disorder (BPD). Emerging evidence suggests that trauma-focused therapy using eye movement desensitization and reprocessing (EMDR) can be beneficial for patients with BPD symptoms. To date, the effects of brief, intensive EMDR treatment for this target group have not been investigated in this population.OBJECTIVE: This study aimed to evaluate the effects of a brief and intensive trauma-focused therapy course using EMDR therapy in two patients diagnosed with BPD who did not fulfill the diagnostic criteria for post-traumatic stress disorder (PTSD). It was hypothesized that this approach would be associated with a decline in the core symptoms of BPD, and that this would have an enduring long-term effect on patients&#039; diagnostic status.METHOD: Ten sessions of EMDR therapy were carried out across four consecutive treatment days, with the aim of processing patients&#039; core adverse childhood experiences. Both A-criterion-worthy memories (without intrusive reliving) and non-A-criterion-worthy memories that were considered responsible for the patients&#039; most prominent symptoms were targeted. The effects of EMDR therapy on trauma symptom severity and BPD diagnostic status (as established by the Structured Clinical Interview DSM-5) were determined. Additionally, the effects on psychological distress, quality of life, and difficulties in emotion regulation were determined at intake, post-treatment, and at 3-, 6-, and 12-months follow-up.RESULTS: Both patients showed a strong decline in psychological distress and difficulties in emotion regulation, and reported an improvement in their quality of life. At post-treatment, and at 3-, 6-, and 12-months follow-up they no longer met the DSM-5 criteria for BPD.CONCLUSION: The findings of this small case study are in line with mounting evidence that a brief track of intensive trauma-focused therapy can result in long-term remission in patients with BPD. EMDR therapy seems to be a promising treatment approach for patients with BPD; however, the results need to be replicated in clinical trials. <p><a href="https://greenmedinfo.com/article/brief-intensive-emdr-therapy-borderline-personality-disorder" target="_blank">read more</a></p> https://greenmedinfo.com/article/brief-intensive-emdr-therapy-borderline-personality-disorder#comments Borderline Personality Disorder Guided Imagery Human: Case Report Sun, 04 Feb 2024 17:08:07 +0000 greenmedinfo 287686 at https://greenmedinfo.com Development of an ambulatory biofeedback app to enhance emotional awareness in patients with borderline personality disorder. https://greenmedinfo.com/article/development-ambulatory-biofeedback-app-enhance-emotional-awareness-patients-bo PMID:  JMIR Mhealth Uhealth. 2019 Oct 15 ;7(10):e13479. Epub 2019 Oct 15. PMID: 31617851 Abstract Title:  Development of an Ambulatory Biofeedback App to Enhance Emotional Awareness in Patients with Borderline Personality Disorder: Multicycle Usability Testing Study. Abstract:  BACKGROUND: Patients with borderline personality disorder experience great difficulties in regulating their emotions. They often are unable to effectively detect their emotional arousal and struggle to timely apply learned techniques for emotion regulation. Although the use of continuous wearable biofeedback has been repeatedly suggested as an option to improve patients&#039; emotional awareness, this type of app is not yet available for clinical use. Therefore, we developed an ambulatory biofeedback app named Sense-IT that can be integrated in mental health care.OBJECTIVE: The aim of the study was to develop an ambulatory biofeedback app for mental health care that helps with learning to better recognize changes in personal emotional arousal and increases emotional awareness.METHODS: Using several methods in a tailored User Centred Design (UCD) framework, we tested the app&#039;s usability and user experience (UX) via a cyclic developmental process with multiple user groups (patients, therapists, and UCD experts; 3-5 per group, per cycle).RESULTS: The process resulted in a stable prototype of the app that meets most of the identified user requirements. The app was valued as useful and usable by involved patients, therapists, and UCD experts. On the Subjective Usability Scale (SUS), the patients rated the app as &quot;Good&quot; (average score of 78.8), whereas the therapists rated the app as &quot;OK&quot; (average score of 59.4). The UCD experts judged the app&#039;s overall usability as between &quot;OK&quot; and &quot;acceptable&quot; (average score of 0.87 on a cognitive walkthrough). As most critical usability problems were identified and addressed in the first cycle of the prototyping process, subsequent cycles were mainly about implementing new or extending existing functions, and other adjustments to improve UX.CONCLUSIONS: mHealth development within a clinical mental health setting is challenging, yet feasible and welcomed by targeted users. This paper shows how new mHealth interventions for mental health care can be met with enthusiasm and openness by user groups that are known to be reluctant to embrace technological innovations. The use of the UCD framework, involving multiple user groups, proved to be of added value during design and realization as evidenced by the complementary requirements and perspectives. Future directions on studying clinical effectiveness of the app, appliance of the app in other fields, and the implications of integration of the app for daily practice in mental health are discussed. <p><a href="https://greenmedinfo.com/article/development-ambulatory-biofeedback-app-enhance-emotional-awareness-patients-bo" target="_blank">read more</a></p> https://greenmedinfo.com/article/development-ambulatory-biofeedback-app-enhance-emotional-awareness-patients-bo#comments Borderline Personality Disorder Biofeedback Human Study Sun, 04 Feb 2024 17:34:22 +0000 greenmedinfo 287700 at https://greenmedinfo.com Does the augmentation of trauma informed hatha yoga increase the effect of dialectical behavior therapy for substance use disorders. https://greenmedinfo.com/article/does-augmentation-trauma-informed-hatha-yoga-increase-effect-dialectical-behav PMID:  Eur Addict Res. 2023 ;29(1):1-8. Epub 2022 Oct 10. PMID: 36215959 Abstract Title:  Does the Augmentation of Trauma Informed Hatha Yoga Increase the Effect of Dialectical Behavior Therapy for Substance Use Disorders on Psychopathological Strain of Patients with Borderline Personality Disorder Abstract:  BACKGROUND: Borderline personality disorder (BPD) is one of the most common personality disorders among persons with substance use disorders (SUDs) and is characterized by severe clinical symptoms. The aim of this study was to investigate if the effect of dialectical behavior therapy for substance use disorders (DBT-S) inpatient treatment on psychopathological symptom load in patients suffering from both BPD and SUD can be augmented by weekly 60-min &quot;Trauma Informed Hatha Yoga&quot; sessions.MATERIALS AND METHODS: Thirty-nine patients suffering from comorbid BPD and SUD were consecutively in time included in this quasi-experimental pilot study (first intervention then control group). In the intervention group, weekly Trauma Informed Hatha Yoga sessions were added to standard DBT-S for 8 weeks. The participants of the control group received standard DBT-S. All participants completed several self-report questionnaires to assess symptoms of depression, anxiety, symptoms of BPD, and their subjective stress perception at three points in time during the study course.RESULTS: A repeated measures analysis of variance with patients&#039; psychopharmacological medication as covariate revealed a significant main effect of time for each of the psychometric scales (State and Trait Anxiety Inventory subscale for state anxiety [STAI-S] p = 0.001, Beck Depression Inventory [BDI] p<p><a href="https://greenmedinfo.com/article/does-augmentation-trauma-informed-hatha-yoga-increase-effect-dialectical-behav" target="_blank">read more</a></p> https://greenmedinfo.com/article/does-augmentation-trauma-informed-hatha-yoga-increase-effect-dialectical-behav#comments Borderline Personality Disorder Substance Use Disorders Yoga Human Study Sun, 04 Feb 2024 17:30:49 +0000 greenmedinfo 287696 at https://greenmedinfo.com Ear acupuncture for co-occurring substance abuse and borderline personality disorder. https://greenmedinfo.com/article/ear-acupuncture-co-occurring-substance-abuse-and-borderline-personality-disord PMID:  Acupunct Med. 2014 Aug ;32(4):318-24. Epub 2014 May 13. PMID: 24824499 Abstract Title:  Ear acupuncture for co-occurring substance abuse and borderline personality disorder: an aid to encourage treatment retention and tobacco cessation. Abstract:  OBJECTIVES: Retention of individuals with co-occurring borderline personality disorder (BPD) and substance use disorders in treatment is known to be difficult. An outcome study of a tobacco-free 90-day inpatient dual-diagnosis treatment programme that uses several evidenced-based treatments in addition to ear acupuncture (acudetox) was undertaken to determine overall treatment effectiveness.METHODS: Between January 2009 and December 2011, 231 patients were treated in the programme, 88% with nicotine dependence and 79% with personality disorder diagnoses. All patients completing the programme were invited to enrol in a 1-year follow-up study in which they responded to monthly questionnaires to assess outcomes.RESULTS: 185 patients (80%) successfully completed the programme. There was no correlation between successful programme completion and gender, race, age, primary drug dependence diagnosis or primary psychiatric diagnosis. The use of acudetox was positively correlated with successful completion (p=0.006). Of the 78 patients with BPD, 100% of men and 83% of women successfully completed the programme. Their use of acudetox was positively correlated with successful completion (p=0.026). At the end of the year, 140 questionnaires were returned: 51 patients with BPD reported outcomes similar to the group as a whole, with 55% sober and doing well.CONCLUSIONS: The use of acudetox was positively correlated with both successful completion of the programme for those with BPD as well as successful tobacco cessation, which ultimately improves the ability to maintain sobriety. <p><a href="https://greenmedinfo.com/article/ear-acupuncture-co-occurring-substance-abuse-and-borderline-personality-disord" target="_blank">read more</a></p> https://greenmedinfo.com/article/ear-acupuncture-co-occurring-substance-abuse-and-borderline-personality-disord#comments Borderline Personality Disorder Smoking Cessation Substance Use Disorders Acupuncture Human Study Sun, 04 Feb 2024 17:39:46 +0000 greenmedinfo 287705 at https://greenmedinfo.com Emotional working memory training (EWMT) has therapeutic effects in Borderline Personality Disorder patients. https://greenmedinfo.com/article/emotional-working-memory-training-ewmt-has-therapeutic-effects-borderline-pers PMID:  J Affect Disord. 2022 Dec 15 ;319:181-188. Epub 2022 Sep 22. PMID: 36155238 Abstract Title:  Emotional working memory training improves cognitive inhibitory abilities in individuals with borderline personality trait: A randomized parallel-group trial. Abstract:  BACKGROUND: Cognitive inhibition impairment is one of the causes of impulsive behaviors in individuals with borderline personality disorder (BPD). This study aimed to investigate the effect of emotional working memory training (EWMT) on cognitive inhibition in individuals with a clinically significant borderline personality trait.METHODS: In a randomized, parallel-group trial, 40 individuals with borderline personality trait, were selected out of 1000 screened individuals and were randomly assigned to the experimental (N = 20) and waiting-list control (N = 20) groups based on the score on the Borderline Personality Scale and the follow-up Structured Clinical Interview for DSM-IV Personality Disorders. The experimental group underwent 10 sessions of EWMT and the control group did not receive any intervention (waiting list). Participants completed the Stroop Color and Word Test (SCWT) and Go/No-Go task Before and after the intervention.RESULTS: EWMT significantly reduced reaction time of incongruent trials in the SCWT and commission errors in the Go/No-Go task after the intervention only in the experimental group. Furthermore, the interference score in SCWT and commission error rate at the post-intervention time were significantly lower for the experimental vs the waitlist group.LIMITATIONS: The single-blind design and absence of follow-up measures.CONCLUSIONS: EWMT can improve cognitive inhibition in individuals with borderline personality trait and could be used for therapeutic purposes of impulsivity behavior in BPD. <p><a href="https://greenmedinfo.com/article/emotional-working-memory-training-ewmt-has-therapeutic-effects-borderline-pers" target="_blank">read more</a></p> https://greenmedinfo.com/article/emotional-working-memory-training-ewmt-has-therapeutic-effects-borderline-pers#comments Borderline Personality Disorder Emotional working memory training (EWMT) Human Study Mon, 26 Dec 2022 21:53:28 +0000 greenmedinfo 268411 at https://greenmedinfo.com Improved emotion regulation after neurofeedback: A single-arm trial in patients with borderline personality disorder. https://greenmedinfo.com/article/improved-emotion-regulation-after-neurofeedback-single-arm-trial-patients-bord PMID:  Neuroimage Clin. 2019 ;24:102032. Epub 2019 Oct 16. PMID: 31795041 Abstract Title:  Improved emotion regulation after neurofeedback: A single-arm trial in patients with borderline personality disorder. Abstract:  Real-time functional magnetic resonance imaging (fMRI) neurofeedback training of amygdala hemodynamic activity directly targets a neurobiological mechanism, which contributes to emotion regulation problems in borderline personality disorder (BPD). However, it remains unknown which outcome measures can assess changes in emotion regulation and affective instability, associated with amygdala downregulation in a clinical trial. The current study directly addresses this question. Twenty-four female patients with a DSM-IV BPD diagnosis underwent four runs of amygdala neurofeedback. Before and after the training, as well as at a six-weeks follow-up assessment, participants completed measures of emotion dysregulation and affective instability at diverse levels of analysis (verbal report, clinical interview, ecological momentary assessment, emotion-modulated startle, heart rate variability, and fMRI). Participants were able to downregulate their amygdala blood oxygen-dependent (BOLD) response with neurofeedback. There was a decrease of BPD symptoms as assessed with the Zanarini rating scale for BPD (ZAN-BPD) and a decrease in emotion-modulated startle to negative pictures after training. Further explorative analyses suggest that patients indicated less affective instability, as seen by lower hour-to-hour variability in negative affect and inner tension in daily life. If replicated by an independent study, our results imply changes in emotion regulation and affective instability for several systems levels, including behavior and verbal report. Conclusions are limited due to the lack of a control group. A randomized controlled trial (RCT) will be needed to confirm effectiveness of the training. <p><a href="https://greenmedinfo.com/article/improved-emotion-regulation-after-neurofeedback-single-arm-trial-patients-bord" target="_blank">read more</a></p> https://greenmedinfo.com/article/improved-emotion-regulation-after-neurofeedback-single-arm-trial-patients-bord#comments Borderline Personality Disorder Neurofeedback Human Study Sun, 04 Feb 2024 17:32:24 +0000 greenmedinfo 287697 at https://greenmedinfo.com In this intervention, n-3 PUFAs significantly improved functioning and reduced psychiatric symptoms compared with placebo. https://greenmedinfo.com/article/intervention-n-3-pufas-significantly-improved-functioning-and-reduced-psychiat PMID:  Can J Psychiatry. 2013 Jul ;58(7):402-8. PMID: 23870722 Abstract Title:  Omega-3 fatty acid supplementation in adolescents with borderline personality disorder and ultra-high risk criteria for psychosis: a post hoc subgroup analysis of a double-blind, randomized controlled trial. Abstract:  OBJECTIVE: To investigate whether long-chain omega-3 (n-3) polyunsaturated fatty acids (PUFAs) improve functioning and psychiatric symptoms in young people with borderline personality disorder (BPD) who also meet ultra-high risk criteria for psychosis.METHODS: We conducted a post hoc subgroup analysis of a double-blind, randomized controlled trial. Fifteen adolescents with BPD (mean age 16.2 years, [SD 2.1]) were randomized to either 1.2 g/day n-3 PUFAs or placebo. The intervention period was 12 weeks. Study measures included the Positive and Negative Syndrome Scale, the Montgomery-Åsberg Depression Rating Scale, and the Global Assessment of Functioning. Side effects were documented with the Udvalg for Kliniske Undersøgelser. Fatty acids in erythrocytes were analyzed using capillary gas chromatography.RESULTS: At baseline, erythrocyte n-3 PUFA levels correlated positively with psychosocial functioning and negatively with psychopathology. By the end of the intervention, n-3 PUFAs significantly improved functioning and reduced psychiatric symptoms, compared with placebo. Side effects did not differ between the treatment groups.CONCLUSIONS: Long-chain n-3 PUFAs should be further explored as a viable treatment strategy with minimal associated risk in young people with BPD. (CLINICAL TRIAL REGISTRATION NUMBER: NCT00396643). https://greenmedinfo.com/article/intervention-n-3-pufas-significantly-improved-functioning-and-reduced-psychiat#comments Borderline Personality Disorder DHA (Docosahexaenoic Acid) EPA (Eicosapentaenoic Acid) Omega-3 Fatty Acids Psychotic Disorders Vitamin E Antipsychotic Agents Significant Treatment Outcome Human Study Thu, 21 May 2015 23:35:42 +0000 greenmedinfo 117644 at https://greenmedinfo.com It was discovered that levels of ADMA and MDA, which reflected oxidative stress, were elevated in patients with BPD. https://greenmedinfo.com/article/it-was-discovered-levels-adma-and-mda-which-reflected-oxidative-stress-were-el PMID:  Psychiatry Investig. 2023 Dec ;20(12):1142-1147. Epub 2023 Dec 18. PMID: 38163653 Abstract Title:  Evaluation of Asymmetric Dimethylarginine, Malondialdehyde, and Vitamin Levels of Borderline Personality Disorder Patients With and Without Self-Mutilation. Abstract:  OBJECTIVE: Believing that oxidative stress may be increased in borderline personality disorder (BPD) patients with self-mutilating behaviors (SMB), we aimed to measure serum asymmetric dimethylarginine (ADMA) and malondialdehyde (MDA) levels in these patients.METHODS: The study included 60 patients diagnosed with BPD and 30 healthy controls. BPD patients were divided into two groups: 30 female patients with SMB and 30 female patients with no-self-mutilating behavior (NSMB). ADMA, MDA, vitamin A, and vitamin E levels were analyzed. Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) were conducted with the participants.RESULTS: Serum ADMA and MDA levels were higher in SMB and NSMB group compared to control group. Serum vitamin E levels were also lower in the SMB group compared to the control group. Positive correlations were determined between both ADMA and MDA, and between BDI and BAI scores. Also, BAI scores were statistically higher in SMB group compared to NSMB group.CONCLUSION: It was discovered that levels of ADMA and MDA, which reflected oxidative stress, were elevated in patients with BPD who exhibited SMB. Accordingly, future studies should investigate the role of oxidative stress in a more comprehensive way in terms of the different mechanisms underlying and treatments involved in borderline personality disorder. <p><a href="https://greenmedinfo.com/article/it-was-discovered-levels-adma-and-mda-which-reflected-oxidative-stress-were-el" target="_blank">read more</a></p> https://greenmedinfo.com/article/it-was-discovered-levels-adma-and-mda-which-reflected-oxidative-stress-were-el#comments Borderline Personality Disorder Oxidative Stress Human Study Sun, 04 Feb 2024 17:14:15 +0000 greenmedinfo 287690 at https://greenmedinfo.com MDMA-assisted psychotherapy for borderline personality disorder. https://greenmedinfo.com/article/mdma-assisted-psychotherapy-borderline-personality-disorder PMID:  Focus (Am Psychiatr Publ). 2022 Oct ;20(4):358-367. Epub 2022 Oct 25. PMID: 37200873 Abstract Title:  MDMA-Assisted Psychotherapy for Borderline Personality Disorder. Abstract:  Borderline personality disorder is a complex psychiatric disorder with limited treatment options that are associated with large heterogeneity in treatment response and high rates of dropout. New or complementary treatments for borderline personality disorder are needed that may be able to bolster treatment outcomes. In this review, the authors comment on the plausibility for research on 3,4-methylenedioxymethamphetamine (MDMA) used in conjunction with psychotherapy for borderline personality disorder (i.e., MDMA-assisted psychotherapy [MDMA-AP]). On the basis of the promise of MDMA-AP in treating disorders overlapping with borderline personality disorder (e.g., posttraumatic stress disorder), the authors speculate on initial treatment targets and hypothesized mechanisms of change that are grounded in prior literature and theory. Initial considerations for designing MDMA-AP clinical trials to investigate the safety, feasibility, and preliminary effects of MDMA-AP for borderline personality disorder are also presented. <p><a href="https://greenmedinfo.com/article/mdma-assisted-psychotherapy-borderline-personality-disorder" target="_blank">read more</a></p> https://greenmedinfo.com/article/mdma-assisted-psychotherapy-borderline-personality-disorder#comments Borderline Personality Disorder Post-Traumatic Stress Disorders (PTSD) Psychedelics:All Review Sun, 04 Feb 2024 17:22:37 +0000 greenmedinfo 287695 at https://greenmedinfo.com Mindfulness training may alleviate negative emotional effects of social rejection among individuals with high borderline personality traits. https://greenmedinfo.com/article/mindfulness-training-may-alleviate-negative-emotional-effects-social-rejection PMID:  Behav Res Ther. 2018 01 ;100:44-53. Epub 2017 Nov 22. PMID: 29179024 Abstract Title:  Effects of brief mindfulness and loving-kindness meditation inductions on emotional and behavioral responses to social rejection among individuals with high borderline personality traits. Abstract:  Borderline personality disorder (BPD) is characterized by an enduring pattern of instability across affective, behavioral, cognitive, and interpersonal domains. Individuals with BPD are known to be particularly vulnerable to experiences of social rejection, but little work has examined strategies that may moderate their reactivity to social rejection. Using a laboratory experimental approach, this study investigated the effects of brief mindfulness and loving-kindness meditation (LKM) inductions on emotional and behavioral responses to social rejection in a sample of adults with high BPD traits. One hundred and eighteen participants were randomly assigned to receive 10 min of mindful breathing practice, LKM, or a no-instruction control condition, prior to exposure to a social rejection manipulation. Participants rated their emotions and completed a competitive reaction time task, which provided a proxy measure of aggression. Compared to the control condition, the mindfulness group demonstrated significantly quicker recovery in negative affect and feelings of rejection after social rejection. The mindfulness group also reported significantly quicker recovery in negative affect compared to the LKM group. Whereas baseline trait mindfulness negatively predicted aggressive behaviors across all participants, groups did not differ in immediate emotional reactivity or aggressive behavior following social rejection. The findings suggest that mindfulness training may be a promising strategy in alleviating negative emotional effects of social rejection among individuals with high borderline personality traits, and highlight the limited utility of brief LKM practice in buffering the effects of social rejection. <p><a href="https://greenmedinfo.com/article/mindfulness-training-may-alleviate-negative-emotional-effects-social-rejection" target="_blank">read more</a></p> https://greenmedinfo.com/article/mindfulness-training-may-alleviate-negative-emotional-effects-social-rejection#comments Borderline Personality Disorder Loving-Kindness Meditation Human Study Tue, 20 Aug 2019 01:24:20 +0000 greenmedinfo 194333 at https://greenmedinfo.com Personality Disorder: Borderline https://greenmedinfo.com/disease/personality-disorder-borderline <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="321" alt="" src="//cdn.greenmedinfo.com/sites/default/files/MentalIssues_6.jpg?1484788780" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_lightwise&#039;&gt;lightwise / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Borderline Personality Disorder Tue, 14 Apr 2009 07:24:16 +0000 greenmedinfo 21518 at https://greenmedinfo.com