Colonic Spasm https://greenmedinfo.com/taxonomy/term/1399/all en The intraluminal administration of peppermint oil by using a hand pump is a simple, safe, and convenient alternative to the systemic injection of a cholinergic blocking agent or glucagon during colonoscopy. https://greenmedinfo.com/article/intraluminal-administration-peppermint-oil-using-hand-pump-simple-safe-and-con PMID:  Gastrointest Endosc. 2001 Feb;53(2):172-7. PMID: 11174287 Abstract Title:  An easy method for the intraluminal administration of peppermint oil before colonoscopy and its effectiveness in reducing colonic spasm. Abstract:  BACKGROUND: Systemic administration of a cholinergic blocking agent or glucagon is used to reduce spasms, but it is inconvenient and sometimes causes side effects. This study is an evaluation of the intracolonic administration of peppermint oil during colonoscopy for the control of colonic spasm. METHODS: Each patient in the treated group (n = 409) was given approximately 200 mL of the solution (a mixture of 8 mL of peppermint oil and 0.2 mL of Tween 80 per 1 L of water with 0.04% indigo carmine) by using a hand pump attached to the accessory channel of the colonoscope. Changes in patient posture were made to distribute the solution. The patients in the control group (n = 36) were given the solution without peppermint oil. RESULTS: A satisfactory spasmolytic effect was seen in 88.5% of the treated patients and in 33.3% of those in the control group (p https://greenmedinfo.com/article/intraluminal-administration-peppermint-oil-using-hand-pump-simple-safe-and-con#comments Colonic Spasm Endoscopy Peppermint Natural Substances Versus Drugs Human Study Sat, 04 Dec 2010 21:42:05 +0000 greenmedinfo 59299 at https://greenmedinfo.com Peppermint has anti-spasm properties during colonscopy. https://greenmedinfo.com/article/peppermint-has-anti-spasm-properties-during-colonscopy PMID:  Acta Gastroenterol Belg. 2012 Sep ;75(3):349-53. PMID: 23082707 Abstract Title:  Premedication with peppermint oil capsules in colonoscopy: a double blind placebo-controlled randomized trial study. Abstract:  BACKGROUND: Colonic spasm is an important problem in colonoscopy for endoscopists to advance the colonoscope and visualize the mucosa.STUDY AIMS: In the present study, we evaluated the efficacy of enteric-coated peppermint oil capsules (Colpermin) as an orally administered antispasmodic premedication in colonoscopy.PATIENTS AND METHODS: Sixty-five adult patients undergoing colonoscopy were randomized to receive either Colpermin (n = 33) or placebo capsules (n = 32) as premedication, 4 hours before the procedure. An experienced endoscopist performed colonoscopy. Outcome measures included cecal intubation and total procedure time, spasm score, pain score, endoscopist satisfaction and patients&#039; willingness to repeat colonoscopy.RESULTS: Duration of both total procedure time and cecal intubation time in patients in the Colpermin group were shorter than that in ones in the placebo group. Scores for colonic spasm and pain were significantly lower in the Colpermin group. The endoscopist satisfaction score was higher in the Colpermin group and patients in the Colpermin group were more willing to repeat colonoscopy in the future.CONCLUSIONS: Premedication with Colpermin was beneficial in terms of the time required for cecal intubation and total procedure time, reducing colonic spasm, increasing endoscopist satisfaction and decreasing pain in patients during colonoscopy. https://greenmedinfo.com/article/peppermint-has-anti-spasm-properties-during-colonscopy#comments Colonic Spasm Peppermint Antispasmodic Human Study Mon, 18 Mar 2013 15:57:00 +0000 greenmedinfo 93410 at https://greenmedinfo.com Peppermint is a simple, safe and inexpensive way to relieve spasm during barium enema. https://greenmedinfo.com/article/peppermint-simple-safe-and-inexpensive-way-relieve-spasm-during-barium-enema PMID:  Br J Radiol. 1995 Aug;68(812):841-3. PMID: 7551780 Abstract Title:  Does peppermint oil relieve spasm during barium enema? Abstract:  The effectiveness of topical peppermint oil added to barium sulphate suspension in relieving colonic muscle spasm during double contrast barium enema examination was assessed in a double blind study. 141 patients were randomized either to a control group (71 patients) examined with standard barium suspension or to the treatment group which received peppermint oil mixed with the barium preparation. No residual spasm was evident in a significant proportion of patients in the treated group (60%) compared with the control group (35%) (p https://greenmedinfo.com/article/peppermint-simple-safe-and-inexpensive-way-relieve-spasm-during-barium-enema#comments Colonic Spasm Endoscopy Peppermint Human Study Sat, 04 Dec 2010 21:44:45 +0000 greenmedinfo 59300 at https://greenmedinfo.com Peppermint oil is a safe and effective alternative for the elimination of colonic spasms instead of Buscopan during a double-contrast barium enema. https://greenmedinfo.com/article/peppermint-oil-safe-and-effective-alternative-elimination-colonic-spasms-inste PMID:  Clin Radiol. 2003 Apr;58(4):301-5. PMID: 12662951 Abstract Title:  Spasmolytic effect of peppermint oil in barium during double-contrast barium enema compared with Buscopan. Abstract:  AIM: To evaluate the efficacy of peppermint oil in barium as a spasmolytic agent during a double-contrast barium enema (DCBE). MATERIALS AND METHODS: A total of 383 DCBEs with positive results from occult blood tests were assessed. Patients were assigned to one of four groups: peppermint in barium (n=91), peppermint in tube (n=90), Buscopan (n=105), or no treatment (n=97). After a screening sigmoidoscopy, the DCBEs were performed using air as a distending gas. In the Buscopan group, the DCBE was performed with an intramuscular injection of 20mg Buscopan at the start of the examination. Patients in the no-treatment group underwent DCBE without any spasmolytic agent. A peppermint oil preparation (30ml) was mixed in the barium solution for patients in the peppermint-in-barium group, and the same dose of peppermint oil was included in the enema tube in the peppermint-in-tube group. The presence of spasm on a series of spot films was evaluated without information about the type of spasmolytic agent used. RESULTS: The percentage of patients in the four groups (no treatment, Buscopan, peppermint in tube, and peppermint in barium) with absence of spasm in the entire colon on the series of spot films was 13.4, 38.1, 41.8, and 37.8%, respectively. In the group using peppermint oil or Buscopan, the rate of patients with non-spasm examination was higher than that in no-treatment group (p&lt;0.0005). Peppermint oil had the same spasmolytic effect as the systemic administration of Buscopan in the transverse and descending colon. Peppermint oil had a stronger effect in the caecum and the ascending colon than a Buscopan injection (p&lt;0.005). There was no advantage to placing peppermint oil in the enema tube over mixing it in the barium solution. A total of 157 polyps were found during the DCBE procedures, and no differences were observed in the number of lesions among the four groups. Peppermint oil did not impair image quality. CONCLUSION: Barium solution mixed with peppermint oil was safe and effective for the elimination of colonic spasm during the DCBE procedure, and it could be used instead of Buscopan. https://greenmedinfo.com/article/peppermint-oil-safe-and-effective-alternative-elimination-colonic-spasms-inste#comments Colonic Spasm Peppermint Antispasmodic Human Study Mon, 20 Apr 2009 06:11:36 +0000 greenmedinfo 42064 at https://greenmedinfo.com Rooibos tea has antispasmodic properties which may be of value in the treatment of hyperactive gastrointestinal disorders. https://greenmedinfo.com/article/rooibos-tea-has-antispasmodic-properties-which-may-be-value-treatment-hyperact PMID:  Basic Clin Pharmacol Toxicol. 2006 Nov;99(5):365-73. PMID: 17076689 Abstract Title:  Antispasmodic effects of Rooibos tea (Aspalathus linearis) is mediated predominantly through K+ -channel activation. Abstract:  Rooibos tea has been widely used for abdominal spasm and diarrhoea. The aim of the present study was to explore the possible mechanism for its use in such ailments. Its aqueous extract (RT) at 0.3-10 mg/ml produced relaxation of spontaneous and low K(+) (25 mM)-induced contractions of rabbit jejunum, with weak effect on high K(+) (80 mM)-induced contractions. In the presence of glibenclamide, relaxation of low K(+)-induced contractions was prevented. Cromakalim inhibited contractions induced by low K(+), but not high K(+), while verapamil did not differentiate in its inhibitory effect on contractions produced by the two concentrations of K(+). RT also exhibited antidiarrhoeal and antisecretory activities in mice. The spasmolytic effect was concentrated in organic fractions. Its constituents, chrysoeriol, orientin and vitexin showed a similar pattern of spasmolytic effects to the extract, while rutin was more like verapamil. So Rooibos tea possesses a combination of dominant K(ATP) channel activation and weak Ca(++) antagonist mechanisms and hence justifies its use in hyperactive gastrointestinal disorders. https://greenmedinfo.com/article/rooibos-tea-has-antispasmodic-properties-which-may-be-value-treatment-hyperact#comments Colonic Spasm Gastric Spasm Rooibos Antispasmodic Animal Study Thu, 09 Jul 2009 14:45:15 +0000 greenmedinfo 45236 at https://greenmedinfo.com The Power of Peppermint: 15 Health Benefits Revealed https://greenmedinfo.com/blog/power-peppermint-15-health-benefits-revealed1 <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2023<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/healing_peppermint_research_greenmedinfo.jpg" style="width: 600px; height: 400px;" /></p> <p><em><strong><span style="font-size:18px;">A favorite herbal medicine of the ancients, peppermint leaves have been found in Egyptian pyramids dating back to 1,000 BC. Modern scientific investigations have now confirmed that this remarkable plant has over a dozen healing properties.</span></strong></em></p> <p><span style="letter-spacing: 0px;">In our continuing effort to educate folks to the vast array of healing agents found in the natural world around us, we are excited to feature peppermint, a member of the aromatic mint family that you may already have squirreled away somewhere in your kitchen cupboard. While most have experienced peppermint as a flavoring agent, or perhaps as a comforting cup of herbal tea, few are aware of its wide range of experimentally confirmed therapeutic properties.&nbsp;</span></p><p><a href="https://greenmedinfo.com/blog/power-peppermint-15-health-benefits-revealed1" target="_blank">read more</a></p> https://greenmedinfo.com/blog/power-peppermint-15-health-benefits-revealed1#comments Colonic Spasm Irritable Bowel Syndrome Peppermint Aromatherapy Health Guide: Essential Oils Sat, 23 Dec 2023 18:36:05 +0000 Sayer Ji 93436 at https://greenmedinfo.com Turmeric has antispasmodic properties. https://greenmedinfo.com/article/turmeric-has-antispasmodic-properties PMID:  PLoS One. 2012 ;7(9):e44650. Epub 2012 Sep 12. PMID: 22984538 Abstract Title:  Curcuma longa Extract Exerts a Myorelaxant Effect on the Ileum and Colon in a Mouse Experimental Colitis Model, Independent of the Anti-Inflammatory Effect. Abstract:  BACKGROUND: Curcuma has long been used as an anti-inflammatory agent in inflammatory bowel disease. Since gastrointestinal motility is impaired in inflammatory states, the aim of this work was to evaluate if Curcuma Longa had any effect on intestinal motility.METHODS: The biological activity of Curcuma extract was evaluated against Carbachol induced contraction in isolated mice intestine. Acute and chronic colitis were induced in Balb/c mice by Dextran Sulphate Sodium administration (5% and 2.5% respectively) and either Curcuma extract (200 mg/kg/day) or placebo was thereafter administered for 7 and 21 days respectively. Spontaneous contractions and the response to Carbachol and Atropine of ileum and colon were studied after colitis induction and Curcuma administration.RESULTS: Curcuma extract reduced the spontaneous contractions in the ileum and colon; the maximal response to Carbachol was inhibited in a non-competitive and reversible manner. Similar results were obtained in ileum and colon from Curcuma fed mice. DSS administration decreased the motility, mainly in the colon and Curcuma almost restored both the spontaneous contractions and the response to Carbachol after 14 days assumption, compared to standard diet, but a prolonged assumption of Curcuma decreased the spontaneous and Carbachol-induced contractions.CONCLUSIONS: Curcuma extract has a direct and indirect myorelaxant effect on mouse ileum and colon, independent of the anti-inflammatory effect. The indirect effect is reversible and non-competitive with the cholinergic agent. These results suggest the use of curcuma extract as a spasmolytic agent. https://greenmedinfo.com/article/turmeric-has-antispasmodic-properties#comments Colonic Spasm Curcumin Intestinal Spasm Antispasmodic Myorelaxant Animal Study Thu, 01 Nov 2012 19:22:24 +0000 greenmedinfo 84170 at https://greenmedinfo.com Wheat bran relieves the symptoms of diverticular disease. https://greenmedinfo.com/article/wheat-bran-relieves-symptoms-diverticular-disease PMID:  Br Med J. 1976 Feb 21;1(6007):425-8. PMID: 766894 Abstract Title:  Diverticular disease: threee studies. Part II - Treatment with bran. Abstract:  Forty patients with diverticular disease were treated with wheat bran 24g/day for at least six months. Thirty-three patients showed a very satisfactory clinical response. Sixty per cent of all symptoms were abolished, and a further 28% were relieved. After treatment the transit times accelerated in patients whose initial times were slower than 60 hours and slowed down in those whose initial transit times were faster than 36 hours. Stool weight increased significantly. The number of intracolonic high pressure waves decreased, especially during and after eating. Barium enema studies showed less spasm in eight patients and no diverticula in three patients after taking bran. As well as relieving the symptoms of diverticular disease a high-fibre diet may also prevent the condition from developing. https://greenmedinfo.com/article/wheat-bran-relieves-symptoms-diverticular-disease#comments Colonic Spasm Diverticular Disease Fiber Wheat Bran Human Study Tue, 26 May 2009 12:46:20 +0000 greenmedinfo 44502 at https://greenmedinfo.com