Hypertension: Portal https://greenmedinfo.com/taxonomy/term/1525/all en Cordyceps mycelia may decrease portal hypertension in rats with chemically induced liver cirrhosis. https://greenmedinfo.com/article/cordyceps-mycelia-may-decrease-portal-hypertension-rats-chemically-induced-liv PMID:  Zhong Xi Yi Jie He Xue Bao. 2008 Nov;6(11):1136-44. PMID: 18990339 Abstract Title:  [Cordyceps mycelia extract decreases portal hypertension in rats with dimethylnitrosamine-induced liver cirrhosis: a study on its histological basis]. Abstract:  OBJECTIVE: To study the effects of Cordyceps mycelia extract (CME) on portal hypertension in rats with dimethylnitrosamine (DMN) induced liver cirrhosis and probe into the mechanism of the action. METHODS: A rat model of liver cirrhosis was induced by peritoneal injection of DMN (at a dose of 10 microg/kg, once a day, 3 consecutive days per week) for 4 weeks. Other 15 rats were assigned into normal control group. The rats in CME-prevented group were administrated CME 0.74 g/(kg.d), once a day, simultaneously with DMN treatment and kept on 4-week administrating, and the rats in CME-treated group were administrated after the model was established. After 3-day, 2- and 4-week DMN injection and 2-, 4-week after the rat liver got cirrhosis, the pressure of portal vein (Ppv) was directly measured by intubation via tributary of vena mesenterica anterior. The serum hyaluronic acid (HA) content was measured by radioimmunoassay. The expressions of CD44, von Willebrand factor (vWF), laminin (LM), alpha-smooth muscle actin (alpha-SMA), type I collagen (Col I) and type IV collagen (Col IV) proteins in the hepatic sinusoida l walls were examined by immunohistochemistry. RESULTS: The caliber of portal vein (Cpv) and Ppv in the CEM group (after 4-week prevention) were significantly decreased as compared with those in the untreated group at the same point of time (P https://greenmedinfo.com/article/cordyceps-mycelia-may-decrease-portal-hypertension-rats-chemically-induced-liv#comments Cordyceps sinensis Hypertension: Portal Liver Cirrhosis Hepatoprotective Animal Study Tue, 23 Feb 2010 17:47:11 +0000 greenmedinfo 52366 at https://greenmedinfo.com Cruveilhier-Baumgarten Syndrome https://greenmedinfo.com/disease/cruveilhier-baumgarten-syndrome <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="433" alt="" src="//cdn.greenmedinfo.com/sites/default/files/LiverAnatomy_5.jpg?1473451367" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_blueringmedia&#039;&gt;blueringmedia / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Hypertension: Portal Tue, 14 Apr 2009 07:16:14 +0000 greenmedinfo 19572 at https://greenmedinfo.com In patients with cirrhosis, dark chocolate blunted the postprandial increase in hepatic venous pressure gradient by improving flow-mediated hepatic vasorelaxation and ameliorated systemic hypotension. https://greenmedinfo.com/article/patients-cirrhosis-dark-chocolate-blunted-postprandial-increase-hepatic-venous PMID:  Am J Clin Nutr. 2012 Jul 18. Epub 2012 Jul 18. PMID: 22811444 Abstract Title:  Postprandial effects of dark chocolate on portal hypertension in patients with cirrhosis: results of a phase 2, double-blind, randomized controlled trial. Abstract:  BACKGROUND: In cirrhosis, hepatic endothelial dysfunction as a result of oxidative stress contributes to the postprandial increase in hepatic venous pressure gradient (HVPG). OBJECTIVE: We aimed at testing the hypothesis that dark chocolate, which holds potent antioxidant properties, might attenuate the postprandial increase in HVPG in patients with cirrhosis. DESIGN: In this phase 2, double-blind, controlled study, 22 cirrhotic patients referred for HVPG measurement were included and randomly assigned to receive a liquid meal containing either dark chocolate (active treatment; 85% cocoa, 0.55 g/kg body wt; n = 11) or isocaloric amounts of white chocolate (devoid of cocoa flavonoids; control subjects; n = 11). HVPG, arterial pressure, portal blood flow, serum flavonoids (catechin and epicatechin), and nitric oxide were measured at baseline and 30 min after meal administration. The main outcome measure was the change in HVPG 30 min after the test meal. RESULTS: Postprandial hyperemia was accompanied by a marked increase in HVPG in the white-chocolate group (16.0± 4.7-19.7 ± 4.1 mm Hg or +26.4 ± 12.7%; P https://greenmedinfo.com/article/patients-cirrhosis-dark-chocolate-blunted-postprandial-increase-hepatic-venous#comments Chocolate Cirrhosis Hypertension: Portal Vasodilator Agents Human Study Fri, 20 Jul 2012 13:37:55 +0000 greenmedinfo 78708 at https://greenmedinfo.com In patients with moderate to severe portopulmonary hypertension, beta-blockers are associated with significant worsening in exercise capacity and pulmonary hemodynamics. https://greenmedinfo.com/article/patients-moderate-severe-portopulmonary-hypertension-beta-blockers-are-associa PMID:  Gastroenterology. 2006 Jan;130(1):120-6. PMID: 16401475 Abstract Title:  Deleterious effects of beta-blockers on exercise capacity and hemodynamics in patients with portopulmonary hypertension. Abstract:  BACKGROUND&amp;AIMS: It has been suggested that beta-blockers might be harmful in pulmonary arterial hypertension. However, no study has evaluated the effect of beta-blockers in these patients. The aim of this study was to investigate the effect of beta-blockers on exercise capacity and pulmonary hemodynamics in patients with portopulmonary hypertension receiving beta-blockers for the prophylaxis of variceal bleeding. METHODS: Ten consecutive patients with moderate to severe portopulmonary hypertension (mean pulmonary artery pressure of 52 [10] mm Hg) underwent a 6-minute walk test and a right heart catheterization at baseline and 2 (1) months after beta-blocker withdrawal. RESULTS: Following beta-blocker withdrawal, 9 of 10 patients increased their 6-minute walked distance with a mean increase in the whole group of 79 (78) meters (P = .01). Cardiac output increased by 28% (P https://greenmedinfo.com/article/patients-moderate-severe-portopulmonary-hypertension-beta-blockers-are-associa#comments Hypertension: Portal Pulmonary Hypertension Beta Blockers Human Study Sat, 13 Mar 2010 02:16:42 +0000 greenmedinfo 53423 at https://greenmedinfo.com