Diverticulosis https://greenmedinfo.com/taxonomy/term/1719/all en Lactobacillus is superior to Mesalazine in the long-term remission of symptomatic uncomplicated diverticular disease of the colon. https://greenmedinfo.com/article/lactobacillus-superior-mesalazine-long-term-remission-symptomatic-uncomplicate PMID:  Hepatogastroenterology. 2008 May-Jun;55(84):916-20. PMID: 18705297 Abstract Title:  Mesalazine and/or Lactobacillus casei in maintaining long-term remission of symptomatic uncomplicated diverticular disease of the colon. Abstract:  BACKGROUND/AIMS: Four different therapeutic schedules with mesalazine and/or probiotics were assessed in preventing recurrence of symptomatic diverticular disease (DD) of the colon.METHODOLOGY: A prospective, dose-finding study was conducted on 75 patients, enrolled in an open fashion: mesalazine 800mg/daily (group M1) or mesalazine 1.6gr 10 days/month (group M2); mesalazine 800mg/daily + Lactobacillus casei DG 16 billion/day for 10 day/month (group LM1) or mesalazine 1.6gr + Lactobacillus casei DG 16 billion/day for 10 day/month (group LM2); Lactobacillus casei DG 16 billion/day for 10 day/month (group L).RESULTS: Seventy one patients completed the study (94.66%). Sixty six patients (88%) were symptom-free after the 24th month of treatment: 11 of group M1 (on i-t-t: 84% [CI 95%: 55.5-98.8]), 8 of group M2 (on i-t-t: 80% [CI 95%: 44.39-97.48]), 15 of group LM1 (on i-t-t: 93.75% [CI 95%: 69.77-99.84]), 12 of group LM2 (on i-t-t: 92.30% [CI 95%: 63.97-99.81]), 20 in group L (on i-t-t: 86.95% [CI 95%: 66.41-97.22]) (p-ns). Four patients (5.33%) suspended the treatment during the follow-up: all experienced recurrence of symptoms (100%), and 2 of them developed diverticulitis (50%).CONCLUSIONS: Mesalazine and/or Lactobacillus casei seem to be effective in maintaining remission of DD for long-time. Moreover, we found recurrence of the disease and complications in all patients suspending treatments. https://greenmedinfo.com/article/lactobacillus-superior-mesalazine-long-term-remission-symptomatic-uncomplicate#comments Diverticular Disease Diverticulitis Diverticulosis Lactobacillus casei Superiority of Natural Substances versus Drugs Human Study Sun, 26 Jun 2011 02:23:40 +0000 greenmedinfo 64917 at https://greenmedinfo.com Physical activity lowers the risk of diverticulitis and diverticular bleeding. https://greenmedinfo.com/article/physical-activity-lowers-risk-diverticulitis-and-diverticular-bleeding PMID:  Am J Gastroenterol. 2009 May;104(5):1221-30. Epub 2009 Apr 14. PMID: 19367267 Abstract Title:  Physical activity decreases diverticular complications. Abstract:  OBJECTIVES: Little is known about the effect of physical activity on diverticular complications. This study prospectively examined the associations between physical activity and diverticular bleeding and diverticulitis. METHODS: We studied 47,228 US males in the Health Professionals Follow-up Study cohort who were aged 40-75 years and free of diverticular disease, gastrointestinal cancer, and inflammatory bowel disease at baseline in 1986. Men reporting newly diagnosed diverticular disease on biennial follow-up questionnaires were sent supplemental questionnaires outlining details of diagnosis and treatment. Physical activity was assessed every 2 years. Men recorded the average time per week spent in eight recreational activities, and flights of stairs climbed per day. Cox proportional hazards regression was used to calculate relative risks (RRs). RESULTS: During 18 years of follow-up, 800 cases of diverticulitis and 383 cases of diverticular bleeding were identified. Total cumulative physical activity was associated with a decreased risk of diverticulitis and diverticular bleeding. After adjustment for potential confounders, the RR for men in the highest quintile of total activity (>or = 57.4 metabolic equivalent hours per week (MET-h/week) was 0.75 (95% confidence interval, CI, 0.58-0.95) for diverticulitis and 0.54 (95% CI, 0.38-0.77) for bleeding, as compared with men in the lowest quintile ( https://greenmedinfo.com/article/physical-activity-lowers-risk-diverticulitis-and-diverticular-bleeding#comments Diverticular Disease Diverticulitis Diverticulosis Exercise Risk Reduction Human Study Fri, 15 Jan 2010 19:25:34 +0000 greenmedinfo 49355 at https://greenmedinfo.com Physical activity, along with a high fiber diet, may be an important factor in the prevention of symptomatic diverticular disease. https://greenmedinfo.com/article/physical-activity-along-high-fiber-diet-may-be-important-factor-prevention-sym PMID:  Gut. 1995 Feb;36(2):276-82. PMID: 7883230 Abstract Title:  Prospective study of physical activity and the risk of symptomatic diverticular disease in men. Abstract:  The relationship between physical activity and risk of symptomatic diverticular disease has not been investigated directly. This association was examined in a prospective cohort of 47,678 American men, 40 to 75 years of age, and free of diagnosed diverticular disease, colon or rectal polyp, ulcerative colitis, and cancer before 1988. During four years of follow up, 382 newly diagnosed cases of symptomatic diverticular disease were documented. After adjustment for age, energy adjusted dietary fibre, and energy adjusted total fat, overall physical activity was inversely associated with the risk of symptomatic diverticular disease (for highest versus lowest extremes, relative risk (RR) = 0.63 (95% confidence interval (CI) 0.45, 0.88). Most of the inverse association was attributable to vigorous activity, for extreme categories RR = 0.60 (95% CI 0.41, 0.87). For activity that was not vigorous the RR was 0.93 (95% CI 0.67, 1.69). Several specific activities were inversely associated with the risk of diverticular disease, but jogging and running combined was the only individual activity that was statistically significant (p for trend = 0.03). For men in the lowest quintile for dietary fibre intake and total physical activity (compared with those in the opposite extreme), the RR was 2.56 (95% CI 1.36, 4.82). Physical activity, along with a high fibre diet, may be an important factor in the prevention of symptomatic diverticular disease. https://greenmedinfo.com/article/physical-activity-along-high-fiber-diet-may-be-important-factor-prevention-sym#comments Diverticular Disease Diverticulitis Diverticulosis Fiber Exercise Risk Reduction Human Study Fri, 15 Jan 2010 19:24:15 +0000 greenmedinfo 49354 at https://greenmedinfo.com There is an inverse association between nut and popcorn consumption and the risk of diverticulitis. https://greenmedinfo.com/article/there-inverse-association-between-nut-and-popcorn-consumption-and-risk-diverti PMID:  JAMA. 2008 Aug 27;300(8):907-14. PMID: 18728264 Abstract Title:  Nut, corn, and popcorn consumption and the incidence of diverticular disease. Abstract:  CONTEXT: Patients with diverticular disease are frequently advised to avoid eating nuts, corn, popcorn, and seeds to reduce the risk of complications. However, there is little evidence to support this recommendation.OBJECTIVE: To determine whether nut, corn, or popcorn consumption is associated with diverticulitis and diverticular bleeding.DESIGN AND SETTING: The Health Professionals Follow-up Study is a cohort of US men followed up prospectively from 1986 to 2004 via self-administered questionnaires about medical (biennial) and dietary (every 4 years) information. Men reporting newly diagnosed diverticulosis or diverticulitis were mailed supplemental questionnaires.PARTICIPANTS: The study included 47,228 men aged 40 to 75 years who at baseline were free of diverticulosis or its complications, cancer, and inflammatory bowel disease and returned a food-frequency questionnaire.MAIN OUTCOME MEASURES: Incident diverticulitis and diverticular bleeding.RESULTS: During 18 years of follow-up, there were 801 incident cases of diverticulitis and 383 incident cases of diverticular bleeding. We found inverse associations between nut and popcorn consumption and the risk of diverticulitis. The multivariate hazard ratios for men with the highest intake of each food (at least twice per week) compared with men with the lowest intake (less than once per month) were 0.80 (95% confidence interval, 0.63-1.01; P for trend = .04) for nuts and 0.72 (95% confidence interval, 0.56-0.92; P for trend = .007) for popcorn. No associations were seen between corn consumption and diverticulitis or between nut, corn, or popcorn consumption and diverticular bleeding or uncomplicated diverticulosis.CONCLUSIONS: In this large, prospective study of men without known diverticular disease, nut, corn, and popcorn consumption did not increase the risk of diverticulosis or diverticular complications. The recommendation to avoid these foods to prevent diverticular complications should be reconsidered. https://greenmedinfo.com/article/there-inverse-association-between-nut-and-popcorn-consumption-and-risk-diverti#comments Diverticular Disease Diverticulitis Diverticulosis Nuts Human Study Fri, 25 Mar 2011 21:35:45 +0000 greenmedinfo 62858 at https://greenmedinfo.com