Fusobacterium Infections https://greenmedinfo.com/taxonomy/term/2199/all en Necrobacillosis https://greenmedinfo.com/disease/necrobacillosis <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="332" alt="" src="//cdn.greenmedinfo.com/sites/default/files/Bacteria_25.jpg?1482540836" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_designua&#039;&gt;designua / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Fusobacterium Infections Tue, 14 Apr 2009 07:22:43 +0000 greenmedinfo 21153 at https://greenmedinfo.com Resveratrol was found to effectively inhibit biofilm formation. https://greenmedinfo.com/article/resveratrol-was-found-effectively-inhibit-biofilm-formation PMID:  Front Microbiol. 2016 ;7:1065. Epub 2016 Jul 5. PMID: 27458454 Abstract Title:  Anti-biofilm Activities from Resveratrol against Fusobacterium nucleatum. Abstract:  Fusobacterium nucleatum is a Gram-negative, anaerobic bacterium that plays an important role in dental plaque biofilm formation. In this study, we evaluate the effect of resveratrol, a phytoalexin compound, on F. nucleatum biofilm formation. The effects of different concentrations of resveratrol on biofilms formed on 96-well microtiter plates at different time points were determined by the MTT assay. The structures and thicknesses of the biofilm were observed by confocal laser scanning microscopy (CLSM), and gene expression was investigated by real-time PCR. The results showed that resveratrol at sub-MIC levels can significantly decrease biofilm formation, whereas it does not affect the bacterial growth rate. It was observed by CLSM images that the biofilm was visually decreased with increasing concentrations of resveratrol. Gene expression was down regulated in the biofilm in the presence of resveratrol. Our results revealed that resveratrol can effectively inhibit biofilm formation. https://greenmedinfo.com/article/resveratrol-was-found-effectively-inhibit-biofilm-formation#comments Fusobacterium Infections Resveratrol Antimicrobial Biofilm Dose Response In Vitro Study Wed, 03 Aug 2016 23:15:58 +0000 greenmedinfo 131514 at https://greenmedinfo.com Sphaerophorus Infections https://greenmedinfo.com/disease/sphaerophorus-infections <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="299" alt="" src="//cdn.greenmedinfo.com/sites/default/files/Lichen.jpg?1487020298" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_kamnuan&#039;&gt;kamnuan / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Fusobacterium Infections Tue, 14 Apr 2009 07:26:29 +0000 greenmedinfo 22069 at https://greenmedinfo.com The dual antibacterial and anti-inflammatory action of lowbush blueberry polyphenols suggests that they may be promising candidates for novel therapeutic agents. https://greenmedinfo.com/article/dual-antibacterial-and-anti-inflammatory-action-lowbush-blueberry-polyphenols- PMID:  J Agric Food Chem. 2015 Aug 4. Epub 2015 Aug 4. PMID: 26207764 Abstract Title:  Wild Blueberry (Vaccinium angustifolium Ait.) Polyphenols Target Fusobacterium nucleatum and the Host Inflammatory Response: Potential Innovative Molecules for Treating Periodontal Diseases. Abstract:  Blueberries contain significant amounts of flavonoids to which a number of beneficial health effects in humans have been associated. The present study investigated the effect of a polyphenol-rich lowbush blueberry (Vaccinium angustifolium Ait.) extract on the two main etiologic components of periodontitis, a multifactorial disorder affecting the supporting structures of the teeth. Phenolic acids, flavonoids (flavonols, anthocyanins, flavan-3-ols), and procyanidins made up 16.6, 12.9, and 2.7% of the blueberry extract, respectively. The blueberry extract showed antibacterial activity (MIC = 1 mg/mL) against the periodontopathogenic bacterium Fusobacterium nucleatum. This property may result from the ability of blueberry polyphenols to chelate iron. Moreover, the blueberry extract at 62.5μg/mL inhibited F. nucleatum biofilm formation by 87.5 ± 2.3%. Subsequently, the ability of the blueberry extract to inhibit the NF-κB signaling pathway in U937-3xκB cells was investigated. The blueberry extract dose-dependently inhibited the activation of NF-κB induced by F. nucleatum. In addition, a pretreatment of macrophages with the blueberry extract (62.5 μg/mL) inhibited the secretion of IL-1β, TNF-α, and IL-6 by 87.3 ± 1.3, 80.7 ± 5.6, and 28.2 ± 9.3%, respectively, following a stimulation with F. nucleatum. Similarly, the secretion of MMP-8 and MMP-9 was also dose-dependently inhibited. This dual antibacterial and anti-inflammatory action of lowbush blueberry polyphenols suggests that they may be promising candidates for novel therapeutic agents. https://greenmedinfo.com/article/dual-antibacterial-and-anti-inflammatory-action-lowbush-blueberry-polyphenols-#comments Blueberry Fusobacterium Infections Periodontal Diseases Polyphenols Anti-Bacterial Agents Anti-Inflammatory Agents Interleukin-1 beta downregulation Interleukin-6 Downregulation Matrix metalloproteinase-8 (MMP-8) inhibitor Matrix metalloproteinase-9 (MMP-9) inhibitor Tumor Necrosis Factor (TNF) Alpha Inhibitor In Vitro Study Fri, 07 Aug 2015 00:35:43 +0000 greenmedinfo 119642 at https://greenmedinfo.com