Childhood Infections https://greenmedinfo.com/taxonomy/term/25411/all en 27 Probiotic Benefits for Children https://greenmedinfo.com/blog/27-probiotic-benefits-children <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2020<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="27 Probiotic Benefits for Chiildren" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/greenmedinfo/images/probiotic_benefits.jpg" style="width: 356px; height: 400px;" /></p> <p class="rtecenter"><span style="font-size:18px;"><strong><span style="color:#008000;">Probiotic Benefits for Children</span></strong></span></p><p><a href="https://greenmedinfo.com/blog/27-probiotic-benefits-children" target="_blank">read more</a></p> https://greenmedinfo.com/blog/27-probiotic-benefits-children#comments Childhood Infections Dysbiosis Gastroenteritis Lactobacilius bulgaricus Lactobacillus Acidophilus Lactobacillus Brevis Prebiotics Probiotics Health Guide: Probiotics children's health microbes probiotics Wed, 06 Jun 2012 16:34:58 +0000 Pat Robinson 76911 at https://greenmedinfo.com Adrenocorticotrophic hormone treatment in infants with infantial spasm may result in increased mortality. https://greenmedinfo.com/article/adrenocorticotrophic-hormone-treatment-infants-infantial-spasm-may-result-incr PMID:  Pediatr Infect Dis J. 1993 Nov;12(11):913-6. PMID: 8265280 Abstract Title:  Risk of infection during adrenocorticotropic hormone treatment in infants with infantile spasms. Abstract:  We reviewed the clinical features and laboratory findings of 27 infants with infantile spasms treated with adrenocorticotropic hormone or prednisone during febrile episodes in order to evaluate the incidence of bacteremia, the risk of serious infection, determination of whether serious infections can be identified at presentation and the outcome of febrile episodes. There were 75 febrile episodes including 4 episodes of identified bacteremia (5.3%). Three children who were treated with adrenocorticotropic hormone dosage larger than recommended died. Leukocytosis and a differential count with many immature granulocytes predicted bacteremia in this population. Chest radiography was useful in identifying the cause of fever. The pathogens isolated were similar to those found in this age range. We conclude that the frequency of bacteremia in our patient population is similar to that observed in infants of the same age; however, the outcome is frequently fatal. In addition this increased mortality may be associated with the use of a larger dosage of adrenocorticotropic hormone than recommended. https://greenmedinfo.com/article/adrenocorticotrophic-hormone-treatment-infants-infantial-spasm-may-result-incr#comments Bacteremia Childhood Infections Febrile Seizures Infantile Spasms Adrenocorticotropic Hormone Drug Iatrogenic Disease Human Study Sat, 27 Feb 2010 17:39:01 +0000 greenmedinfo 52806 at https://greenmedinfo.com An herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children. https://greenmedinfo.com/article/herbal-preparation-containing-echinacea-propolis-and-vitamin-c-preventing-resp PMID:  Arch Pediatr Adolesc Med. 2004 Mar;158(3):217-21. PMID: 14993078 Abstract Title:  Effectiveness of an herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children: a randomized, double-blind, placebo-controlled, multicenter study. Abstract:  OBJECTIVE: To evaluate the effectiveness and safety of a preparation containing echinacea, propolis, and vitamin C in the prevention of respiratory tract infections in children during a 12-week winter period.DESIGN: Randomized, double-blind, placebo-controlled study.SUBJECTS: Four hundred thirty children, aged 1 to 5 years, were randomized to an herbal extract preparation (n = 215) or a placebo elixir (n = 215).INTERVENTION: Administration of an herbal preparation (Chizukit) containing 50 mg/mL of echinacea, 50 mg/mL of propolis, and 10 mg/mL of vitamin C, or placebo (5.0 mL and 7.5 mL twice daily for ages 1 to 3 years and 4 to 5 years, respectively) for 12 weeks.RESULTS: Significant mean +/- SD reductions of illnesses were seen in the Chizukit group in the number of illness episodes, 138 vs 308 (55% reduction); number of episodes per child, 0.9 +/- 1.1 vs 1.8 +/- 1.3 (50% reduction, P https://greenmedinfo.com/article/herbal-preparation-containing-echinacea-propolis-and-vitamin-c-preventing-resp#comments Bee Propolis Childhood Infections Common Cold Echinacea Upper Respiratory Infections Vitamin C Human Study Wed, 22 Dec 2010 02:25:06 +0000 greenmedinfo 59735 at https://greenmedinfo.com Antibiotics have only modest efficacy (1 in 8) in treating persistent nasal discharge (rhinosinusitis) in children. https://greenmedinfo.com/article/antibiotics-have-only-modest-efficacy-1-8-treating-persistent-nasal-discharge- PMID:  Cochrane Database Syst Rev. 2008(2):CD001094. Epub 2008 Apr 16. PMID: 18425867 Abstract Title:  WITHDRAWN: Antibiotics for persistent nasal discharge (rhinosinusitis) in children. Abstract:  BACKGROUND: Nasal discharge (rhinosinusitis) is extremely common in children. It is the result of inflammation of the mucosa of the upper respiratory tract, and is usually due to either infection or allergy. Infections may be caused by bacteria. OBJECTIVES: To determine the effectiveness of antibiotics versus placebo or standard therapy in treating children with persistent nasal discharge (rhinosinusitis) for at least 10 days. SEARCH STRATEGY: In this updated review, we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 1, 2005) which includes the ARI Group&#039;s specialised trials register; MEDLINE (1966 to April Week 3, 2005) EMBASE (1997 to December 2004), and the references of relevant articles were searched. Authors and pharmaceutical companies were contacted. SELECTION CRITERIA: All randomised controlled trials that compared antibiotics versus placebo or standard therapy. Trials which included the use of other medications were included if all participants were allowed equal access to such medications or if the additional or alternative therapies were regarded as ineffective. Trials that only combined or compared antibiotics with surgery, or sinus puncture and lavage, were not included in the review. DATA COLLECTION AND ANALYSIS: Data were extracted by a single author for the following eight outcomes: overall clinical failure (primary outcome), failure to cure, failure to improve, clinical improvement, time to resolution, complications, side-effects and bacteriologic failure. For the dichotomous outcome variables of each individual study, proportional and absolute risk reductions were calculated using a modified intention-to-treat analysis. The summary weighted risk ratio and 95% confidence interval (CI) (fixed effect model) were calculated using the inverse of the variance of each study result for weighting (Cochrane statistical package, RevMan version 4.2). MAIN RESULTS: A total of six studies involving 562 children compared antibiotics with placebo or standard therapy. All studies were randomised but most were still susceptible to bias. Five of the studies were conducted in emergency, allergy or ENT clinics. Four of the studies required children to have x-ray changes consistent with sinusitis. Only the primary outcome (overall clinical failure) was reported in all studies. Around 40% of all randomised children did not have a clinical success documented when reviewed two to six weeks after randomisation. The control event rate varied from to 22 to 71% (mean 46%). The risk ratio estimated using a fixed effects model was 0.75 (95% CI 0.61 to 0.92). There was no evidence of statistical heterogeneity. Side effects (sufficient to cease treatment) occurred in 4 of 189 control group children (four studies). More children treated with antibiotics had side effects (17 of 330), but this difference was not statistically significant (RR 1.75, 95% CI 0.63 to 4.82). AUTHORS&#039; CONCLUSIONS: For children with persistent nasal discharge or older children with radiographically confirmed sinusitis, the available evidence suggests that antibiotics will reduce the probability of persistence in the short to medium-term. The benefits appear to be modest and around eight children must be treated in order to achieve one additional cure (number needed to treat (NNT) 8, 95% CI 5 to 29). No long term benefits have been documented. These conclusions are based on a small number of small randomised controlled trials and may require revision as additional data become available. https://greenmedinfo.com/article/antibiotics-have-only-modest-efficacy-1-8-treating-persistent-nasal-discharge-#comments Childhood Infections Rhinosinusitis Antibiotics Human Study Mon, 12 Apr 2010 16:43:59 +0000 greenmedinfo 53740 at https://greenmedinfo.com BCG revaccination may raise mortality in young children. https://greenmedinfo.com/article/bcg-revaccination-may-raise-mortality-young-children PMID:  BMJ. 2010;340:c671. Epub 2010 Mar 15. PMID: 20231251 Abstract Title:  Effect of revaccination with BCG in early childhood on mortality: randomised trial in Guinea-Bissau. Abstract:  OBJECTIVE: To determine whether BCG revaccination at 19 months of age reduces overall child mortality. DESIGN: Randomised trial, with follow-up to age 5. SETTING: A health project in Bissau, Guinea-Bissau, which maintains a health and demographic surveillance system in an urban area with 90 000 inhabitants. PARTICIPANTS: 2871 children aged 19 months to 5 years with low or no reactivity to tuberculin and who were not severely sick on the day of enrollment. INTERVENTION: BCG vaccination or no vaccination (control). MAIN OUTCOME MEASURE: Hazard ratios for mortality. RESULTS: 77 children died during follow-up. Compared with controls, the BCG revaccinated children had a hazard ratio of 1.20 (95% confidence interval 0.77 to 1.89). Two hundred and fifty children were admitted to hospital for the first time between enrollment and the end of the study, with an incidence rate ratio for BCG revaccinated children versus controls of 1.04 (0.81 to 1.33). The trial was stopped prematurely because of a cluster of deaths in the BCG arm of the study. This increase in mortality occurred at a time when many children had received missing vaccinations or vitamin A or iron supplementation; the hazard ratio for BCG revaccinated children compared with controls was 2.69 (1.05 to 6.88) in the period after these campaigns. Throughout the trial, the effect of BCG revaccination on mortality was significantly different (P=0.006) in children who had received diphtheria-tetanus-pertussis (DTP) booster vaccination before enrollment (hazard ratio 0.36, 0.13 to 0.99) and children who had not received the booster before enrollment (1.78, 1.04 to 3.04). CONCLUSIONS: There was no overall beneficial effect of being revaccinated with BCG. The effect of BCG revaccination on mortality might depend on other health interventions. Trial registration Clinical Trials ICA4-CT-2002-10053-REVAC. https://greenmedinfo.com/article/bcg-revaccination-may-raise-mortality-young-children#comments Childhood Infections Tuberculosis Vaccination: BCG (Tuberculosis) Human Study Sat, 27 Mar 2010 15:51:13 +0000 greenmedinfo 53553 at https://greenmedinfo.com Breast-feeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against Haemophilus influenzae. https://greenmedinfo.com/article/breast-feeding-associated-reduced-frequency-acute-otitis-media-and-high-serum- PMID:  Pediatr Res. 2009 Nov;66(5):565-70. PMID: 19581824 Abstract Title:  Breast-feeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against NTHi and outer membrane protein vaccine antigen candidate P6. Abstract:  Nontypeable Haemophilus influenzae (NTHi) causes acute otitis media (AOM) in infants. Breast-feeding protects against AOM and/or nasopharyngeal (NP) colonization; however, the mechanism of protection is incompletely understood. Children with AOM and healthy children were studied according to feeding status: breastfed,breast/formula fed, or formula fed. Cumulative episodes of AOM, ELISA titers of serum IgG antibodies to whole-cell NTHi and vaccine candidate outer membrane protein P6, bactericidal titers of serum and NP colonization by NTHi were assessed. A lower incidence of AOM was found in breast- versus formula-fed children. Levels of specific serum IgG antibody to NTHi and P6 were highest in breast-fed, intermediate in breast/formula fed, and lowest in formula-fed infants. Serum IgG antibody to P6 correlated with bactericidal activity against NTHi. Among children with AOM, the prevalence of NTHi in the NP was lower in breast- versus nonbreast-fed infants. We conclude that breast-feeding shows an association with higher levels of antibodies to NTHi and P6, suggesting that breast-feeding modulates the serum immune response to NTHi and P6. Higher serum IgG might facilitate protection against AOM and NP colonization in breast-fed children. https://greenmedinfo.com/article/breast-feeding-associated-reduced-frequency-acute-otitis-media-and-high-serum-#comments Breast Milk Childhood Infections Ear Infection Haemophilus influenzae Breastfeeding Immunostimulatory Human Study Tue, 05 Apr 2011 23:57:50 +0000 greenmedinfo 63083 at https://greenmedinfo.com Children exposed to proton pump inhibitor therapy are at higher risk for the development of Clostridium difficile-associated disease. https://greenmedinfo.com/article/children-exposed-proton-pump-inhibitor-therapy-are-higher-risk-development-clo PMID:  Aliment Pharmacol Ther. 2009 Dec 29. Epub 2009 Dec 29. PMID: 20047577 Abstract Title:  Proton pump inhibitors as a risk factor for paediatric Clostridium difficile infection. Abstract:  Summary Background: Proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) may play an important role on the onset of Clostridium difficile-associated disease (CDAD) in adults. The impact of Clostridium difficile on children treated with gastric acid-suppressing agents is unknown. Aim: To investigate the relationship between CDAD and exposure to acid suppressive therapy in hospitalized pediatric patients. Patients and Methods: We reviewed the medical records of children with a diagnosis of protracted diarrhea and abdominal pain, whose stool was analyzed for C. difficile toxins. We identified 68 patients with CDAD. For each case patient, we randomly selected one control subjects with stool analysis negative for C. difficile. Comorbid illnesses, previous hospitalizations, antibiotics, corticosteroids, immunosuppressants and gastric acid suppressing exposures were recorded. Results: The use of PPI was significantly higher in C. difficile positive group compared with C. difficile negative group [odds ratio (OR): = 4.5; 95% confidence interval (CI) = 1.4 to 14.4]. We also found a trend for the use of H(2)RAs in patients infected by C. difficile respect to C. difficile negative comparison groups (OR: = 3.8; 95% CI = 0.7 to 18.9). Conclusions: Children exposed to PPIs therapy seem to be at higher risk for the development of CDAD. https://greenmedinfo.com/article/children-exposed-proton-pump-inhibitor-therapy-are-higher-risk-development-clo#comments Acid Reflux: In Infants & Children Childhood Infections Clostridium Infections Infant Infections Proton-Pump Inhibitors Iatrogenic Disease Human Study Sat, 27 Feb 2010 18:30:10 +0000 greenmedinfo 52822 at https://greenmedinfo.com Ciprofloxacin, a fluoroquinolone antibacterial agent, is not recommended in pediatric population on account of its possible adverse effect on growing cartilage. https://greenmedinfo.com/article/ciprofloxacin-fluoroquinolone-antibacterial-agent-not-recommended-pediatric-po PMID:  Indian Pediatr. 1992 Feb;29(2):181-8. PMID: 1592498 Abstract Title:  Adverse drug reaction monitoring of ciprofloxacin in pediatric practice. Abstract:  Ciprofloxacin, a fluoroquinolone antibacterial agent, is not recommended in pediatric population on account of its possible adverse effect on growing cartilage. It is being commonly used for treatment of variety of infections in children in our country and very little information is available on the risks involved in its use. A questionnaire was sent to 750 pediatricians in the last week of November 1990, to retrospectively judge over the previous 2 month period the extent of its use and identify the adverse drug reactions (ADRs). One hundred and fifty-four pediatricians replied, of which 147 had prescribed ciprofloxacin in a total of 3341 patients under 18 years of age, enteric fever being the commonest indication for its use. One hundred and fifty-nine ADRs were reported in 104 (3.1%) patients. They were: gastrointestinal in 50% of these 104 patients, CNS in 23%, skin and allergic in 19.1%, musculoskeletal in 8.6%, hematological in 3.8%, CVS in 2.9% and nephrological in 0.9% cases. Of 159 ADRs, 8 (5%) were severe, 76 (47.8%) were moderate and 75 (47.2%) were mild. Therapy needed discontinuation in only 9 (0.3%) patients. Two new ADRs were identified, viz., sudden death after intravenous ciprofloxacin and sinus nodal arrest causing bradycardia. https://greenmedinfo.com/article/ciprofloxacin-fluoroquinolone-antibacterial-agent-not-recommended-pediatric-po#comments Childhood Infections Cipro Human Study Fri, 09 Apr 2010 19:07:46 +0000 greenmedinfo 53705 at https://greenmedinfo.com Ear Infection https://greenmedinfo.com/disease/ear-infection <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="336" alt="" src="//cdn.greenmedinfo.com/sites/default/files/Ear_8.jpg?1474411755" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_peterjunaidy&#039;&gt;peterjunaidy / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <div class="field field-wikipedia"> <div class="field-items"> <div class="field-item odd"> <a href="http://en.wikipedia.org/wiki/Otitis_media" 0="s:6:&quot;a:0:{}&quot;;" target="_blank">Otitis media</a> </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 61 </div> </div> </div> </fieldset> Childhood Infections Pneumococcal Infections Tue, 14 Apr 2009 07:17:03 +0000 greenmedinfo 19784 at https://greenmedinfo.com Echinacea appears effective in preventing upper respiratory tract infections in children. https://greenmedinfo.com/article/echinacea-appears-effective-preventing-upper-respiratory-tract-infections-chil PMID:  J Altern Complement Med. 2005 Dec;11(6):1021-6. PMID: 16398593 Abstract Title:  Echinacea purpurea for prevention of upper respiratory tract infections in children. Abstract:  OBJECTIVE: The aim of this study was to determine whether Echinacea purpurea given to children for the treatment of acute upper respiratory tract infection (URI) was effective in reducing the risk of subsequent URI.DESIGN: This was a secondary analysis of data from a randomized, double-blind, placebo-controlled trial of Echinacea for the treatment of URI in children.SETTING: The study was conducted as a joint project between the Puget Sound Pediatric Research Network (Seattle, WA) and Bastyr University (Kenmore, WA).PARTICIPANTS: A total of 524 children ages 2 to 11 years were enrolled in the study.INTERVENTION: Children were monitored for URIs over a 4-month observation period during the fall/winters of 2000-2001 and 2001-2002. At entry the children were randomized to receive Echinacea or placebo to treat acute URIs during the observation period.MAIN OUTCOME MEASURES: The occurrence of a second URI and the number of days between the end of the first URI and the start of the second URI was ascertained. Survival and Cox regression analyses were used to determine whether children who took Echinacea for their URIs were less likely to develop subsequent URIs.RESULTS: Among the 401 children with at least one URI treated with study medication, 69.2% of those receiving placebo developed a second URI versus 55.8% of those who received Echinacea. Use of Echinacea was associated with a 28% decreased risk of subsequent URI (p = 0.01, 95% confidence interval 8%-44% decreased risk).CONCLUSIONS: Echinacea purpurea may be effective in reducing the occurrence of subsequent URIs in children. However this finding needs to be replicated in a URI prevention trial. https://greenmedinfo.com/article/echinacea-appears-effective-preventing-upper-respiratory-tract-infections-chil#comments Childhood Infections Common Cold Echinacea Respiratory Diseases Upper Respiratory Infections Plant Extracts Human Study Wed, 22 Dec 2010 04:12:53 +0000 greenmedinfo 59769 at https://greenmedinfo.com Green banana and pectin are useful in the dietary management of persistent diarrhea in hospitalized children and may also be useful to treat children at home. https://greenmedinfo.com/article/green-banana-and-pectin-are-useful-dietary-management-persistent-diarrhea-hosp PMID:  Gastroenterology. 2001 Sep;121(3):554-60. PMID: 11522739 Abstract Title:  Clinical studies in persistent diarrhea: dietary management with green banana or pectin in Bangladeshi children. Abstract:  BACKGROUND &amp; AIMS: Because of the beneficial intestinal effects of dietary fibers, we have evaluated the therapeutic effects of green banana or pectin in children with persistent diarrhea.METHODS: In a double-blind trial, 62 boys, age 5-12 months, were randomly given a rice-based diet containing either 250 g/L of cooked green banana (n = 22) or 4 g/kg pectin (n = 19) or the rice-diet alone (control, n = 21), providing 54 kcal/dL daily for 7 days. Stool weight and consistency, frequency of vomiting and purging, and duration of illness were measured.RESULTS: Most children (60%) had no pathogens isolated from stools, 17% had rotavirus, 5% Vibrio cholerae, 4% Salmonella group B, and 11% had enterotoxigenic Escherichia coli infections. By day 3 posttreatment, significantly (P https://greenmedinfo.com/article/green-banana-and-pectin-are-useful-dietary-management-persistent-diarrhea-hosp#comments Banana Childhood Infections Diarrhea Diarrhea: in Children Pectin Antidiarrheals Human Study Wed, 22 Dec 2010 20:42:00 +0000 greenmedinfo 59802 at https://greenmedinfo.com Guillain-Barré syndrome following H1N1 immunization in a pediatric patient has been reported. https://greenmedinfo.com/article/guillain-barr-syndrome-following-h1n1-immunization-pediatric-patient-has-been- PMID:  Ann Pharmacother. 2010 Jul-Aug;44(7-8):1330-3. Epub 2010 May 18. PMID: 20484170 Abstract Title:  Guillain-Barré syndrome following H1N1 immunization in a pediatric patient. Abstract:  OBJECTIVE: To report a case of Guillain-Barré syndrome (GBS) following a dose of influenza A (H1N1) vaccine (Arepanrix).CASE SUMMARY: An 11-year-old boy was admitted to the hospital after presenting with facial diplegia; abdominal, forehead, and thigh pain; and acute cervical pain. He had received the Arepanrix H1N1 subcutaneous vaccine 13 days before symptom onset. The neurologic examination also revealed a symmetric bilateral paralysis of the VIIth cranial nerve and intense pain, proximal weakness of the shoulder girdles and pelvis, and preserved deep tendon reflexes. Cerebrospinal fluid analysis revealed an albuminocytologic dissociation. Therefore, a diagnosis of atypical GBS following vaccination against HINI influenza was made.DISCUSSION: Based on the clinical evaluation, laboratory test results, neurologic features, and the exclusion of alternative diagnoses, the Naranjo probability scale revealed a probable relationship between the clinical manifestations of GBS and the vaccine against influenza A (H1N1) received by the patient. This is the first published case for the 2009 influenza pandemic in children.CONCLUSIONS: While recent studies have found inconclusive results on the association between influenza vaccine and GBS, all suspected cases should be published for further evaluation. https://greenmedinfo.com/article/guillain-barr-syndrome-following-h1n1-immunization-pediatric-patient-has-been-#comments Childhood Infections Guillain-Barre Syndrome Influenza Vaccine-induced Toxicity Vaccination: All Vaccination: Influenza Human: Case Report Wed, 29 Dec 2010 19:22:12 +0000 greenmedinfo 59917 at https://greenmedinfo.com Gut Biota Never Recover from Antibiotics: Damages Future Generations https://greenmedinfo.com/blog/gut-biota-never-recover-antibiotics-damages-future-generations <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2013<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p><em><strong>The misuse of antibiotics is not only causing new, never-before known diseases like E. coli and MRSA, the flesh-eating bacteria, it's also destroying the gut biome with devastating effects on our ability to deal with infections and destroying our ability to absorb nutrients from food.</strong></em></p> <p class="rtecenter"><img alt="Gut Biota Never Recover from Antibiotics: Damages Future Generations" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/Immunocompromised.jpg" /></p> <p><em>by Heidi Stevenson</em>, originally published on <a href="http://gaia-health.com/gaia-blog/2013-04-13/gut-biota-never-recover-from-antibiotics-damages-future-generations/" target="_blank">Gaia Health</a>.</p> <p>Emerging research shows that the harmful effects of antibiotics go much further than the development of drug resistant diseases. The beneficial bacteria lost to <strong><a href="/blog/reflection-antibiotics">antibiotics</a></strong>, along with disease-inducing bacteria, do not fully recover. Worse, flora lost by a mother is also lost to her babies. The missing <strong><a href="/substance/probiotics">beneficial gut bacteria</a></strong> are likely a major factor behind much of the chronic disease experienced today. The continuous use of antibiotics is resulting in each generation experiencing worse health than their parents.</p> <p>Martin Blaser, the author of a report in the prestigious journal <i>Nature</i> writes:</p> <blockquote> <div> <p>Antibiotics kill the bacteria we do want, as well as those we don't. These long-term changes to the beneficial bacteria within people's bodies may even increase our susceptibility to infections and disease.Overuse of antibiotics could be fuelling the dramatic increase in conditions such as obesity, type 1 diabetes, inflammatory bowel disease, allergies and asthma, which have more than doubled in many populations.</p> </div> </blockquote> <p>Without even considering the development of superbugs, we're now seeing clear documentation that the overall long term effects of antibiotics are devastatingly harmful to our health. Speaking to ABC News, Blaser said:</p> <blockquote> <p>Antibiotics are miraculous. They've changed health and medicine over the last 70 years. But when doctors prescribe antibiotics, it is based on the belief that there are no long-term effects. <b>We've seen evidence that suggests antibiotics may permanently change the beneficial bacteria that we're carrying.</b> [Emphasis my own.]</p> </blockquote> <p>Notice that term, <strong>permanent</strong>. Without factoring in the potential risks in the casual use of antibiotics, it now looks like conventional medicine is creating several pandemics of some of the worst chronic diseases known.</p> <p><a href="https://greenmedinfo.com/blog/gut-biota-never-recover-antibiotics-damages-future-generations" target="_blank">read more</a></p> https://greenmedinfo.com/blog/gut-biota-never-recover-antibiotics-damages-future-generations#comments Antibiotic Toxicity Childhood Chemical Exposures Childhood Infections Childhood Poisoning Dysbiosis Infection: Antibiotic Resistant MRSA Anti-Bacterial Agents Antibiotics Antibiotics Antibiotics: Intrapartum Antimicrobial Iatrogenic Disease Wed, 05 Jun 2013 12:00:00 +0000 GaiaHealth 100169 at https://greenmedinfo.com High dose vitamin D3 prevents recurrence of pneumonia in children treated with antibiotics. https://greenmedinfo.com/article/high-dose-vitamin-d3-prevents-recurrence-pneumonia-children-treated-antibiotic PMID:  Trop Med Int Health. 2010 Oct;15(10):1148-55. Epub 2010 Aug 17. PMID: 20723187 Abstract Title:  Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial. Abstract:  OBJECTIVES: To determine whether (i) supplementation of oral 100,000 iu of vitamin D(3) (cholecalciferol) along with antibiotics will reduce the duration of illness in children with pneumonia; (ii) supplementation will reduce the risk of repeat episodes. METHODS: Double-blind individually randomised placebo-controlled trial in an inner-city hospital in Kabul, of 453 children aged 1-36 months, diagnosed with non-severe or severe pneumonia at the outpatient clinic. Children with rickets, other concurrent severe diseases, very severe pneumonia or wheeze, were excluded. Children were given vitamin D(3) or placebo drops additional to routine pneumonia treatment. RESULTS: Two hundred and twenty-four children received vitamin D(3;) and 229 received placebo. There was no significant difference in the mean number of days to recovery between the vitamin D(3) (4.74 days; SD 2.22) and placebo arms (4.98 days; SD 2.89; P = 0.17). The risk of a repeat episode of pneumonia within 90 days of supplementation was lower in the intervention (92/204; 45%) than the placebo group [122/211; (58%; relative risk 0.78; 95% CI 0.64, 0.94; P = 0.01]. Children in the vitamin D(3) group survived longer without experiencing a repeat episode (72 days vs. 59 days; HR 0.71; 95% CI 0.53-0.95; P = 0.02). CONCLUSION: A single high-dose oral vitamin D(3) supplementation to young children along with antibiotic treatment for pneumonia could reduce the occurrence of repeat episodes of pneumonia. https://greenmedinfo.com/article/high-dose-vitamin-d3-prevents-recurrence-pneumonia-children-treated-antibiotic#comments Childhood Infections Pneumonia Upper Respiratory Infections Vitamin D Anti-Bacterial Agents Drug Synergy Human Study Fri, 10 Dec 2010 00:14:32 +0000 greenmedinfo 59439 at https://greenmedinfo.com Influenza vaccines were not shown to be effective among children 6 to 59 months of age during 2 influenza seasons. https://greenmedinfo.com/article/influenza-vaccines-were-not-shown-be-effective-among-children-6-59-months-age- PMID:  Anticancer Res. 2009 Nov;29(11):4629-32. PMID: 18838647 Abstract Title:  Influenza vaccine effectiveness among children 6 to 59 months of age during 2 influenza seasons: a case-cohort study. Abstract:  OBJECTIVE: To measure vaccine effectiveness (VE) in preventing influenza-related health care visits among children aged 6 to 59 months during 2 consecutive influenza seasons. DESIGN: Case-cohort study estimating effectiveness of inactivated influenza vaccine in preventing inpatient/outpatient visits (emergency department [ED] and outpatient clinic). We compared vaccination status of laboratory-confirmed influenza cases with a cluster sample of children from a random sample of practices in 3 counties (subcohort) during the 2003-2004 and 2004-2005 seasons. SETTING: Counties encompassing Rochester, New York, Nashville, Tennessee, and Cincinnati, Ohio. PARTICIPANTS: Children aged 6 to 59 months seen in inpatient/ED or outpatient clinic settings for acute respiratory illnesses and community-based subcohort comparison. Main Exposure Influenza vaccination. MAIN OUTCOME MEASURES: Influenza vaccination status of cases vs subcohort using time-dependent Cox proportional hazards models to estimate VE in preventing inpatient/ED and outpatient visits. RESULTS: During the 2003-2004 and 2004-2005 seasons, 165 and 80 inpatient/ED and 74 and 95 outpatient influenza cases were enrolled, while more than 4500 inpatient/ED and more than 600 outpatient subcohorts were evaluated, respectively. In bivariate analyses, cases had lower vaccination rates than subcohorts. However, significant influenza VE could not be demonstrated for any season, age, or setting after adjusting for county, sex, insurance, chronic conditions recommended for influenza vaccination, and timing of influenza vaccination (VE estimates ranged from 7%-52% across settings and seasons for fully vaccinated 6- to 59-month-olds). CONCLUSION: In 2 seasons with suboptimal antigenic match between vaccines and circulating strains, we could not demonstrate VE in preventing influenza-related inpatient/ED or outpatient visits in children younger than 5 years. Further study is needed during years with good vaccine match. https://greenmedinfo.com/article/influenza-vaccines-were-not-shown-be-effective-among-children-6-59-months-age-#comments Childhood Infections Influenza Vaccine-induced Toxicity Vaccination: All Vaccination: Influenza Human Study Thu, 25 Mar 2010 02:17:58 +0000 greenmedinfo 53550 at https://greenmedinfo.com