Legionellosis https://greenmedinfo.com/taxonomy/term/2997/all en Cinamaldehyde exhibits inhibitory activity against Legionella pneumophila. https://greenmedinfo.com/article/cinamaldehyde-exhibits-inhibitory-activity-against-legionella-pneumophila PMID:  Water Res. 2008 Jan ;42(1-2):278-86. Epub 2007 Jul 14. PMID: 17659763 Abstract Title:  Antibacterial activities of plant essential oils against Legionella pneumophila. Abstract:  The objective of this study was to determine the antimicrobial activity of essential oils (EOs) extracted from Cinnamomum osmophloeum leaves and different tissues of Cryptomeria japonica against pathogenic Legionella pneumophila at 42 degrees C. Ten kinds of EOs were extracted by water distillation and their chemical constituents were quantified by gas chromatography-mass spectroscopy (GC-MS). The results showed that cinnamon leaf EO possessed stronger anti-L. pneumophila activity than C. japonica EO. In particular, the highest bactericidal effect was noted in contact with C. osmophloeum leaf EO of cinnamaldehyde type (characterized by its major constituent of cinnamaldehyde accounting for 91.3% of EO), regardless of contacted cell concentration (2 and 4 log CFU ml(-1)) or exposure time (10 and 60 min). Cinnamaldehyde is responsible for anti-L. pneumophila activity based on the results of antimicrobial testing and statistical analysis. Stepwise regression analyses show that EO concentration is the most significant factor affecting the bioactivity of EO. It is concluded that C. osmophloeum leaf oil of cinnamaldehyde type and its major constituent, cinnamaldehyde, possess strong anti-L. pneumophila activities, and have the great potential to be used as an antibacterial agent to control legionellosis associated with hot tubs and spa facilities widely used in homes and resorts. https://greenmedinfo.com/article/cinamaldehyde-exhibits-inhibitory-activity-against-legionella-pneumophila#comments Cinnamaldehyde Legionella pneumophila Legionellosis Legionnaires' disease Anti-Bacterial Agents In Vitro Study Sun, 25 Mar 2012 18:56:10 +0000 greenmedinfo 73637 at https://greenmedinfo.com Cinnamon oil has significant antimicrobial activity against Legionella penuomphila. https://greenmedinfo.com/article/cinnamon-oil-has-significant-antimicrobial-activity-against-legionella-penuomp PMID:  Brain Res. 2006 Nov 20;1120(1):183-90. Epub 2006 Sep 20. PMID: 18945470 Abstract Title:  Influence of pH on bioactivity of cinnamon oil against Legionella pneumophila and its disinfection efficacy in hot springs. Abstract:  Cinnamon oil extracted from leaves of Cinnamomum osmophloeum has recently been proved as a promising antibacterial agent against Legionella pneumophila, an etiological agent of human pneumonia known as Legionnaires&#039; disease. However, the pH effects on the efficacy of cinnamon oil against L. pneumophila and its applicability to recreational spring water remain unknown. We therefore determined the bactericidal activity of cinnamon oil at pH 3-10 in phosphate-buffered saline (PBS) and in four kinds of springs with various conductivity (259-5595 micros cm(-1)) and pH (2.1-7.7) levels. Results show L. pneumophila cells were more susceptible to cinnamon oil at pH 8-10 than at pH 4-6 in PBS, which became more evident as increasing contact time from 10 to 60 min. An increase in concentration of cinnamon oil and contact time significantly increased the anti-L. pneumophila activity (P&lt; or =0.001), indicating a consistent biocidal effect regardless of pH. Interestingly, this dose-response biocidal effect was also observed in spring waters. Moreover, L. pneumophila of 4 log CFU ml(-1) in spring waters was completely inactivated within 60 min by cinnamon oil at 300-750 microg ml(-1), with the highest inactivation in alkaline hydrogen carbonate spring. The great bioactivity of cinnamon oil demonstrates its potential to be used to control Legionella growth in recreational spring water and possibly other niches generally at basic pH, e.g., cooling towers. https://greenmedinfo.com/article/cinnamon-oil-has-significant-antimicrobial-activity-against-legionella-penuomp#comments Cinnamon Legio Legionellosis Legionnaires' disease In Vitro Study Sun, 24 May 2009 15:18:47 +0000 greenmedinfo 44464 at https://greenmedinfo.com Legionnaires' disease https://greenmedinfo.com/disease/legionnaires-disease <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="450" alt="" src="//cdn.greenmedinfo.com/sites/default/files/LegionnairesDisease_2.jpg?1479238744" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_designua&#039;&gt;designua / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <div class="field field-wikipedia"> <div class="field-items"> <div class="field-item odd"> <a href="http://en.wikipedia.org/wiki/Legionella" 0="a:0:{}" target="_blank">Legionella</a> </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Legionellosis Sun, 24 May 2009 15:17:07 +0000 greenmedinfo 44463 at https://greenmedinfo.com