Memory Disorders https://greenmedinfo.com/taxonomy/term/3223/all en Corilagin ameliorates sleep deprivation-induced memory impairments by inhibiting NOX2 and activating Nrf2. https://greenmedinfo.com/article/corilagin-ameliorates-sleep-deprivation-induced-memory-impairments-inhibiting- PMID:  Brain Res Bull. 2020 Jul ;160:141-149. Epub 2020 May 8. PMID: 32389388 Abstract Title:  Corilagin ameliorates sleep deprivation-induced memory impairments by inhibiting NOX2 and activating Nrf2. Abstract:  Sleep deprivation (SD) can induce cognitive and memory impairments. This impairment is in part due to oxidative stress damage in the hippocampus region of the brain. Corilagin (CL), a polyphenol belonging to the tannin family and extracted from Terminalia chebula and Phyllanthus emblica, shows strong antioxidant and neuroprotective effects. NF-E2-related factor (Nrf2)/heme oxygenase-1 (HO-1) and NADPH oxidase (NOX) are critical targets involved in cellular defense mechanisms against oxidative injury. Thus, we hypothesized that CL could be a preventive treatment for SD-induced memory impairments by inhibiting NOX2 and activating Nrf2. The results from behavioral tests showed that administration of CL resulted in significantly better performance compared to the SD mice. CL significantly normalized the elevated MDA level and the reduced activity of GPx and SOD (P<p><a href="https://greenmedinfo.com/article/corilagin-ameliorates-sleep-deprivation-induced-memory-impairments-inhibiting-" target="_blank">read more</a></p> https://greenmedinfo.com/article/corilagin-ameliorates-sleep-deprivation-induced-memory-impairments-inhibiting-#comments Memory Disorders Phyllanthus emblica Polyphenols Sleep Disorders Terminalia chebula Antioxidants Neuroprotective Agents Nrf2 activation In Vitro Study Thu, 16 Jul 2020 17:48:30 +0000 greenmedinfo 223636 at https://greenmedinfo.com Dopamine, norepinephrine, epinephrine, and serotonin, and their regulating enzymes decreased the in hippocampus of microwave-exposed animals https://greenmedinfo.com/article/dopamine-norepinephrine-epinephrine-and-serotonin-and-their-regulating-enzymes PMID:  Cell Biochem Biophys. 2015 Sep ;73(1):93-100. PMID: 25672490 Abstract Title:  Effect of Low-Intensity Microwave Radiation on Monoamine Neurotransmitters and Their Key Regulating Enzymes in Rat Brain. Abstract:  The increasing use of wireless communication devices has raised major concerns towards deleterious effects of microwave radiation on human health. The aim of the study was to demonstrate the effect of low-intensity microwave radiation on levels of monoamine neurotransmitters and gene expression of their key regulating enzymes in brain of Fischer rats. Animals were exposed to 900 MHz and 1800 MHz microwave radiation for 30 days (2 h/day, 5 days/week) with respective specific absorption rates as 5.953 × 10(-4) and 5.835 × 10(-4) W/kg. The levels of monoamine neurotransmitters viz. dopamine (DA), norepinephrine (NE), epinephrine (E) and serotonin (5-HT) were detected using LC-MS/MS in hippocampus of all experimental animals. In addition, mRNA expression of key regulating enzymes for these neurotransmitters viz. tyrosine hydroxylase (TH) (for DA, NE and E) and tryptophan hydroxylase (TPH1 and TPH2) (for serotonin) was also estimated. Results showed significant reduction in levels of DA, NE, E and 5-HT in hippocampus of microwave-exposed animals in comparison with sham-exposed (control) animals. In addition, significant downregulation in mRNA expression of TH, TPH1 and TPH2 was also observed in microwave-exposed animals (p <p><a href="https://greenmedinfo.com/article/dopamine-norepinephrine-epinephrine-and-serotonin-and-their-regulating-enzymes" target="_blank">read more</a></p> https://greenmedinfo.com/article/dopamine-norepinephrine-epinephrine-and-serotonin-and-their-regulating-enzymes#comments Learning disorders Memory Disorders Microwave Radiation Neurotoxic Wi-Fi Radiation Brain Function Cognitive Skills Wi-Fi Devices Animal Study Tue, 30 Jul 2019 20:58:46 +0000 greenmedinfo 192376 at https://greenmedinfo.com Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination. https://greenmedinfo.com/article/piperine-ameliorated-memory-impairment-and-myelin-damage-lysolecethin-induced- PMID:  Life Sci. 2020 Jul 15 ;253:117671. Epub 2020 Apr 24. PMID: 32335165 Abstract Title:  Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination. Abstract:  AIMS: We still do not have effective treatment for hippocampal demyelination and memory deficit, the two common comorbidities in multiple sclerosis (MS). This study aimed to assess the therapeutic effect of Piperine (the main alkaloid of black pepper) in an experimental model of demyelination.MAIN METHODS: Demyelination was induced in male Wistar rats by bilateral injection of lysolecithin (LPC) into the CA1 region of the hippocampus. Piperine (5, 10, 20 mg/kg) was daily injected intraperitoneally three days post LPC injection for ten days. The spatial memory was examined by the Morris water maze task. Demyelination and astrocyte activation were assessed by an immunohistological study. The gene expression analysis of TNF-α, IL1-β, NF-κB, IL-10, Foxp3, iNOS, Nrf2, HO1, MBP, and BDNF was done using qPCR. The total antioxidant capacity of hippocampal tissue was measured using FRAP assay.KEY FINDINGS: Our results showed that piperine improved the memory performance and myelin repair in the hippocampal demyelination model. Piperine inhibited iNOS expression concomitant with enhanced expression levels of Nrf2, HO1 and the total antioxidant capacity in the hippocampal tissue. Piperine treatment significantly reduced the gene expression level of TNF-α, IL1-β, NF-κB, and glial activation in the injured area; however, the mRNA level of IL-10, Foxp3, BDNF and MBP were significantly increased.SIGNIFICANCE: We found piperine to be an effective treatment for spatial memory impairment and myelin repair in the hippocampal demyelination model. However, further experimental evidence is needed to investigate the precise mechanisms underlying piperine as a promising therapeutic target in MS patients. <p><a href="https://greenmedinfo.com/article/piperine-ameliorated-memory-impairment-and-myelin-damage-lysolecethin-induced-" target="_blank">read more</a></p> https://greenmedinfo.com/article/piperine-ameliorated-memory-impairment-and-myelin-damage-lysolecethin-induced-#comments Memory Disorders Piperine Anti-Inflammatory Agents Antioxidants Interleukin-1 beta downregulation Neuroprotective Agents NF-kappaB Inhibitor Tumor Necrosis Factor (TNF) Alpha Inhibitor Animal Study Tue, 18 Aug 2020 16:36:56 +0000 greenmedinfo 225416 at https://greenmedinfo.com 'Rosemary Is For Remembrance' ~ Science Confirms Wisdom of the Ancients https://greenmedinfo.com/blog/rosemary-remembrance-science-confirms-wisdom-ancients <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2014<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="'Rosemary Is For Remembrance' ~ Science Confirms Wisdom of the Ancients" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/rosemary_for_memory.jpg" style="width: 650px; height: 298px;" /></p> <p class="rtecenter"><span style="font-size:18px;"><em><strong>"There's rosemary, that's for remembrance..." </strong></em></span></p> <p class="rtecenter">~ William Shakespeare</p> <p><strong>Since ancient times, herbs have been appreciated for their profound therapeutic effects. </strong>Science as a form of evidence-gathering did not take the epistemological pole position until quite recently in cultural history, with the evidence of direct experience and the senses being the method and the means for ascertaining the medicinal value of plant medicines and foods for countless generations stretching back to the dawn of the human experience.&nbsp;</p><p><a href="https://greenmedinfo.com/blog/rosemary-remembrance-science-confirms-wisdom-ancients" target="_blank">read more</a></p> https://greenmedinfo.com/blog/rosemary-remembrance-science-confirms-wisdom-ancients#comments Aging: Brain Alzheimer's Disease Cognitive Decline/Dysfunction Memory Disorders Memory Loss Rosemary Rosemary: Essential Oil Ergogenic Health Guides: Healing Foods EATomology Natural Substances Versus Drugs Wed, 09 Jul 2014 13:41:59 +0000 Sayer Ji 113151 at https://greenmedinfo.com 2.45-GHz microwave radiation impairs hippocampal learning and spatial memory. https://greenmedinfo.com/article/245-ghz-microwave-radiation-impairs-hippocampal-learning-and-spatial-memory PMID:  Toxicol Sci. 2018 Feb 1 ;161(2):349-374. PMID: 29069439 Abstract Title:  From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling. Abstract:  Microwave (MW) radiation induced oxidative stress reduces dendritic arborization, spine density and number of hippocampal pyramidal neurons and hence, impair learning and spatial memory through p53-dependent/independent apoptosis of hippocampal neuronal and nonneuronal cells. However, the mechanisms responsible for MW radiation induced impairment in memory formation remains still unknown. This study elucidates the effect of short (15 days) and long-term (30 and 60 days) low level 2.45 GHz MW radiation-induced local stress on the hippocampal spatial memory formation pathway in adult male mice. Twelve-weeks old mice were exposed to 2.45 GHz MW radiation (continuous-wave with overall average Power density of 0.0248 mW/cm2 and overall average whole body SAR value of 0.0146 W/Kg) @ 2 h/d for 15, 30, and 60 days. Learning and spatial memory was assessed by 8-arm radial maze. We have investigated the alterations in serum corticosterone level and the expression of glucocorticoid receptor, corticotropin-releasing hormone (CRH), inducible nitric oxide synthase (i-NOS), iGluRs, PSD-95-neuronal NOS (n-NOS) system, protein kinase A, protein kinase Cε-ERK1/2-pERK1/2 in all the hippocampal subregions, viz. CA1, CA2, CA3, and DG through immunohistochemistry/immunofluorescence and alterations in the expression of hippocampal glucocorticoid receptor, CRH-receptor 1 (CRH-R1), cAMP-response element-binding (CREB), and phosphorylated-CREB (p-CREB) through western blot analysis. We observed that 2.45 GHz MW irradiated mice showed slow learning and significantly increased number of working and reference memory errors in radial maze task. Further, 2.45 GHz MW radiation exposure increases serum corticosterone level and the expression of CRH, CRH-R1, and i-NOS, while the expression of iGluRs, n-NOS, PSD-95, protein kinase Cε, protein kinase A, ERK-p-ERK, CREB, and p-CREB decreases in above mentioned hippocampal subregions in a duration dependent manner. Our findings led us to conclude that 2.45 GHz MW radiation exposure induced local stress suppresses signaling mechanism(s) of hippocampal memory formation. <p><a href="https://greenmedinfo.com/article/245-ghz-microwave-radiation-impairs-hippocampal-learning-and-spatial-memory" target="_blank">read more</a></p> https://greenmedinfo.com/article/245-ghz-microwave-radiation-impairs-hippocampal-learning-and-spatial-memory#comments Memory Disorders Microwave Radiation Neurotoxic Animal Study Mon, 30 Apr 2018 19:07:34 +0000 greenmedinfo 163506 at https://greenmedinfo.com 4 weeks of frankincense consumption facilitates the acquisition and retention of motor memory in older men with moderate mental status. https://greenmedinfo.com/article/4-weeks-frankincense-consumption-facilitates-acquisition-and-retention-motor-m PMID:  Turk J Med Sci. 2019 08 8 ;49(4):1033-1040. Epub 2019 Aug 8. PMID: 31317694 Abstract Title:  Effect of 4 weeks of frankincense consumption on explicit motor memory and serum BDNF in elderly men Abstract:  Background/aim: Memory is a mechanism for coding, storing, and recalling information. Weak memory and learning disability are common psychological problems in the elderly. The aim of this study was to investigate the effect of 4 weeks of frankincense consumption on explicit motor memory and serum BDNF in the elderly.Materials and methods: Twenty elderly men (mean age of 60.2± 1.7 years) were randomly divided into two groups: experimental (n = 12) and placebo (n = 8). The first blood samples were collected 24 h before the pretest. Then both groups participated in a 4-week exercise program based on the protocol of exercising motor memory. During this period,the experimental group received 500-mg frankincense pills two times a day. The second blood sample collection and acquisition test were conducted following the last session of the exercise program. A retention test and a third blood sampling were performed 2 weeks after the last training session. Mixed analysis of variance (2 × 3) for repeated measures was used to analyze the data.Results: Intergroup comparisons showed that frankincense had a significant effect on the acquisition and retention of explicit motor memory. No difference was observed in serum BDNF between the experimental and placebo groups.Conclusion: This study revealed that 4 weeks of frankincense consumption facilitates the acquisition and retention of motor memory in older men with moderate mental status. <p><a href="https://greenmedinfo.com/article/4-weeks-frankincense-consumption-facilitates-acquisition-and-retention-motor-m" target="_blank">read more</a></p> https://greenmedinfo.com/article/4-weeks-frankincense-consumption-facilitates-acquisition-and-retention-motor-m#comments Frankincense Memory Disorders Brain-derived neurotrophic factor modulator Neuroprotective Agents Human Study Sat, 07 Dec 2019 03:09:53 +0000 greenmedinfo 203974 at https://greenmedinfo.com 4 weeks of moderate exercise improves memory dysfunction in type 2 diabetes. https://greenmedinfo.com/article/4-weeks-moderate-exercise-improves-memory-dysfunction-type-2-diabetes PMID:  Diabetologia. 2016 Dec 8. Epub 2016 Dec 8. PMID: 27928614 Abstract Title:  Moderate exercise ameliorates dysregulated hippocampal glycometabolism and memory function in a rat model of type 2 diabetes. Abstract:  AIMS/HYPOTHESIS: Type 2 diabetes is likely to be an independent risk factor for hippocampal-based memory dysfunction, although this complication has yet to be investigated in detail. As dysregulated glycometabolism in peripheral tissues is a key symptom of type 2 diabetes, it is hypothesised that diabetes-mediated memory dysfunction is also caused by hippocampal glycometabolic dysfunction. If so, such dysfunction should also be ameliorated with moderate exercise by normalising hippocampal glycometabolism, since 4 weeks of moderate exercise enhances memory function and local hippocampal glycogen levels in normal animals.METHODS: The hippocampal glycometabolism in OLETF rats (model of human type 2 diabetes) was assessed and, subsequently, the effects of exercise on memory function and hippocampal glycometabolism were investigated.RESULTS: OLETF rats, which have memory dysfunction, exhibited higher levels of glycogen in the hippocampus than did control rats, and breakdown of hippocampal glycogen with a single bout of exercise remained unimpaired. However, OLETF rats expressed lower levels of hippocampal monocarboxylate transporter 2 (MCT2, a transporter for lactate to neurons). Four weeks of moderate exercise improved spatial memory accompanied by further increase in hippocampal glycogen levels and restoration of MCT2 expression independent of neurotrophic factor and clinical symptoms in OLETF rats.CONCLUSIONS/INTERPRETATION: Our findings are the first to describe detailed profiles of glycometabolism in the type 2 diabetic hippocampus and to show that 4 weeks of moderate exercise improves memory dysfunction in type 2 diabetes via amelioration of dysregulated hippocampal glycometabolism. Dysregulated hippocampal lactate-transport-related glycometabolism is a possible aetiology of type-2-diabetes-mediated memory dysfunction. <p><a href="https://greenmedinfo.com/article/4-weeks-moderate-exercise-improves-memory-dysfunction-type-2-diabetes" target="_blank">read more</a></p> https://greenmedinfo.com/article/4-weeks-moderate-exercise-improves-memory-dysfunction-type-2-diabetes#comments Diabetes Mellitus: Type 2 Memory Disorders Exercise Neuroprotective Agents Animal Study Fri, 03 Feb 2017 15:51:28 +0000 greenmedinfo 142979 at https://greenmedinfo.com 7 Proven Ways to Keep Your Brain Young https://greenmedinfo.com/blog/7-proven-ways-keep-your-brain-young <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2024<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/chocolate_aging_brain_greenmedinfo.jpg" style="width: 600px; height: 399px;" /></p> <p><em style="font-size: 18px; letter-spacing: 0px;"><strong>Over 5 million Americans have been diagnosed with Alzheimer's. Another 10,000,000 suffer with severe dementia and Parkinson's. Even more struggle with age-related mild cognitive impairment.&nbsp;Here are 7 natural ways to defend your brain.</strong></em></p><p><a href="https://greenmedinfo.com/blog/7-proven-ways-keep-your-brain-young" target="_blank">read more</a></p> https://greenmedinfo.com/blog/7-proven-ways-keep-your-brain-young#comments Aging Aging: Brain Alzheimer's Disease Bacopa Curcumin Dementia Ginkgo biloba Memory Disorders Postmenopausal Disorders: Memory Impairment Turmeric Neuroprotective Agents Aging Alzheimer's disease Bacopa biloba brain CURCUMIN dementia Memory Disorders neuroprotective Neuroprotective Agents prevent brain aging Turmeric Sat, 17 Feb 2024 02:48:05 +0000 GMI reporter 113126 at https://greenmedinfo.com 7 Reasons to Love Rosemary https://greenmedinfo.com/blog/7-reasons-love-rosemary <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2022<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/blank.justin/images/7_Reasons_to_Love_Rosemary-GreenMedInfo.jpg" style="width: 600px; height: 315px;" /></p> <p><span style="font-size:18px;"><em><strong>You may not realize it, but you probably have one of nature's most powerful substances in your kitchen right now. Say hello to your new best friend, rosemary</strong></em></span></p> <p><span style="letter-spacing: 0px;">Rosemary is, understandably, one of the world's most popular herbs. When you brush the branches of a rosemary bush, the fragrant aromatics that emit intoxicate the senses. A desirable shrub, rosemary is found in planters and backyard greenspaces the world over, thanks to its pleasing appearance and hardy growth. Culinary and lifestyle enthusiasts favor rosemary for the delicate flavor and fragrance it imparts when cooked and infused in oils.</span></p><p><a href="https://greenmedinfo.com/blog/7-reasons-love-rosemary" target="_blank">read more</a></p> https://greenmedinfo.com/blog/7-reasons-love-rosemary#comments Chronic Pain Depression Inflammation Memory Disorders Oxidative Stress Rosemary Rosemary: Essential Oil Stress and Anxiety Health Guide: Farm/Pharma Face Off Health Guide: Herbs and Traditional Knowledge Health Guides: Healing Foods healing foods natural health rosemary Fri, 07 Oct 2022 23:18:24 +0000 GMI Research Group 264575 at https://greenmedinfo.com 7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence. https://greenmedinfo.com/article/78-dihydroxyflavone-alleviated-high-fat-diet-and-alcohol-induced-memory-impair PMID:  Psychopharmacology (Berl). 2020 Jun ;237(6):1827-1840. Epub 2020 Mar 23. PMID: 32206827 Abstract Title:  7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence. Abstract:  RATIONALE: Alcoholism and obesity impart a deleterious impact on human health and affects the quality of life. Chronic consumption of alcohol and western diet has been reported to cause memory deficits. 7,8-dihydroxyflavone (7,8-DHF), a TrkB agonist, comprises antioxidant and anti-inflammatory properties in treating various neurological disorders.OBJECTIVES: The current study was aimed to determine the protective effect and molecular mechanism of 7,8-DHF against alcohol and high-fat diet (HFD)-induced memory deficits in rats.METHODS: The adult male Wistar rats were given alcohol (3-15%) and HFD ad libitum for 12 weeks in different experimental groups. 7,8-DHF (5 mg/kg) was intraperitoneally injected daily for the last 4 weeks (9th-12th week).RESULTS: The alcohol and HFD administration caused cognitive impairment as evaluated through the Morris water maze (MWM) test in alcohol, HFD, and alcohol + HFD-fed animals. The last 4-week treatment of 7,8-DHF (5 mg/kg; i.p.) attenuated alcohol and HFD-induced memory loss. 7,8-DHF treatment also restored the glutathione (GSH) level along with attenuation of nitrite, malondialdehyde content (markers of oxidative and nitrosative stress), and reduction of the acetylcholinesterase activity in the hippocampus of alcohol and HFD-fed animals. Furthermore, the administration of 7,8-DHF caused downregulation of NF-κB, iNOS, and caspase-3 and upregulation of Nrf2, HO-1, and BDNF mRNA level in rat hippocampus.CONCLUSION: 7,8-DHF administration conferred beneficial effects against alcohol and HFD-induced memory deficit via its unique antioxidant, anti-inflammatory, anti-apoptotic potential, along with the activation of TrkB/BDNF signaling pathway in the hippocampus. <p><a href="https://greenmedinfo.com/article/78-dihydroxyflavone-alleviated-high-fat-diet-and-alcohol-induced-memory-impair" target="_blank">read more</a></p> https://greenmedinfo.com/article/78-dihydroxyflavone-alleviated-high-fat-diet-and-alcohol-induced-memory-impair#comments Alcohol Toxicity High Fat Diet Memory Disorders Oxidative Stress Antioxidants Brain-derived neurotrophic factor modulator Heme oxygenase-1 up-regulation Neuroprotective Agents Nrf2 activation Animal Study Tue, 12 Oct 2021 00:05:27 +0000 greenmedinfo 247165 at https://greenmedinfo.com 7,8-dihydroxyflavone and neuropsychiatric disorders. https://greenmedinfo.com/article/78-dihydroxyflavone-and-neuropsychiatric-disorders PMID:  Curr Neuropharmacol. 2021 Sep 15. Epub 2021 Sep 15. PMID: 34525922 Abstract Title:  7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development. Abstract:  7,8-Dihydroxyflavone (7,8-DHF) is a kind of natural flavonoids, with the potential to cross the blood-brain barrier. 7,8-DHF effectively mimics the effect of brain-derived neurotrophic factor (BDNF) in the brain to selectively activate tyrosine kinase receptor B (TrkB) and downstream signaling pathways, thus playing a neuroprotective role. The preclinical effects of 7,8-DHF have been widely investigated in the neuropsychiatric disorders, including Alzheimer&#039;s disease (AD), Parkinson&#039;s disease (PD), depression and memory impairment. Besides the effect on TrkB, 7,8-DHF could also function through fighting against oxidative stress, cooperating with estrogen receptors or regulating intestinal flora. This review focuses on the recent experimental studies on depression, neurodegenerative diseases and learning and memory function. Additionally, the structural modification and preparation of 7,8-DHF were also concluded and proposed, hoping to provide reference for the follow-up research and clinical drug development of 7,8-DHF in the field of neuropsychiatric disorders. <p><a href="https://greenmedinfo.com/article/78-dihydroxyflavone-and-neuropsychiatric-disorders" target="_blank">read more</a></p> https://greenmedinfo.com/article/78-dihydroxyflavone-and-neuropsychiatric-disorders#comments Alzheimer's Disease Depression Learning disorders Memory Disorders Psychiatric Disorders Antioxidants Neuroprotective Agents Review Mon, 11 Oct 2021 19:22:29 +0000 greenmedinfo 247135 at https://greenmedinfo.com 8 Benefits of Pine Bark Extract for Your Brain https://greenmedinfo.com/blog/8-benefits-pine-bark-extract-your-brain <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2022<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/blank.justin/images/8_Benefits_of_Pine_Bark_Extract_for_Your_Brain-GreenMedInfo.jpg" style="width: 600px; height: 315px;" /></p> <p><span style="font-size:18px;"><em><strong>Our brains can be harmed by many factors such as disease, stress from the environment, physical injuries or natural aging but pine bark extract may be one key to a healthier brain</strong></em></span></p> <p>Pine bark extract (PE), trade name Pycnogenol (pronounced "pig-nah-gen-all"), has many beneficial properties such as being anti-inflammatory, antioxidant and <a href="https://www.greenmedinfo.com/pharmacological-action/neuroprotective-agents">neuroprotective</a>. It can help with memory, cognition, inattention, hyperactivity, mood, thinking and various symptoms of brain injuries, aging and neurological diseases.</p> <p><strong>1.</strong> <strong>Fights Inflammation and Protects the Brain</strong></p><p><a href="https://greenmedinfo.com/blog/8-benefits-pine-bark-extract-your-brain" target="_blank">read more</a></p> https://greenmedinfo.com/blog/8-benefits-pine-bark-extract-your-brain#comments ADHD Alzheimer's Disease Cognitive Decline/Dysfunction Inflammation Memory Disorders Oxidative Stress Parkinson's Disease Pine Bark Extract Pycnogenol (Pine Bark) Traumatic Brain Injury Health Guide: Farm/Pharma Face Off Health Guide: Herbs and Traditional Knowledge alternative medicine natural health pine bark Wed, 31 Aug 2022 23:52:00 +0000 DianeFulton 262704 at https://greenmedinfo.com 916 MHz electromagnetic fields influence learning and memory in rats to some extent in a period during exposure. https://greenmedinfo.com/article/916-mhz-electromagnetic-fields-influence-learning-and-memory-rats-some-extent- PMID:  Neurol Sci. 2013 Feb ;34(2):157-64. Epub 2012 Feb 24. PMID: 22362331 Abstract Title:  Effects of long-term electromagnetic field exposure on spatial learning and memory in rats. Abstract:  With the development of communications industry, mobile phone plays an important role in daily life. Whether or not the electromagnetic radiation emitted by mobile phone causes any adverse effects on brain function has become of a great concern. This paper investigated the effect of electromagnetic field on spatial learning and memory in rats. 32 trained Wistar rats were divided into two groups: exposure group and control group. The exposure group was exposed to 916 MHz, 10w/m2 mobile phone electromagnetic field (EMF) 6 h a day, 5 days a week, 10 weeks. The completion time, number of total errors and the neuron discharge signals were recorded while the rats were searching for food in an eight-arm radial maze at every weekend. The neuron signals of one exposed rat and one control rat in the maze were obtained by the implanted microelectrode arrays in their hippocampal regions. It can be seen that during the weeks 4-5 of the experiment, the average completion time and error rate of the exposure group were longer and larger than that of control group (p<p><a href="https://greenmedinfo.com/article/916-mhz-electromagnetic-fields-influence-learning-and-memory-rats-some-extent-" target="_blank">read more</a></p> https://greenmedinfo.com/article/916-mhz-electromagnetic-fields-influence-learning-and-memory-rats-some-extent-#comments Cognitive Decline/Dysfunction Memory Disorders Electromagnetic Field Harms Electromagnetic Radiation Animal Study Thu, 03 Oct 2019 21:59:21 +0000 greenmedinfo 197960 at https://greenmedinfo.com A blueberry powder could can facilitate better episodic memory performance and improve cardiovascular function over 6 months. https://greenmedinfo.com/article/blueberry-powder-could-can-facilitate-better-episodic-memory-performance-and-i PMID:  Nutrients. 2018 May 23 ;10(6). Epub 2018 May 23. PMID: 29882843 Abstract Title:  A Randomized, Double-Blinded, Placebo-Controlled Study to Compare the Safety and Efficacy of Low Dose Enhanced Wild Blueberry Powder and Wild Blueberry Extract (ThinkBlue™) in Maintenance of Episodic and Working Memory in Older Adults. Abstract:  Previous research has shown beneficial effects of polyphenol-rich diets in ameliorating cognitive decline in aging adults. Here, using a randomized, double blinded, placebo-controlled chronic intervention, we investigated the effect of two proprietary blueberry formulations on cognitive performance in older adults; a whole wild blueberry powder at 500 mg (WBP500) and 1000 mg (WBP1000) and a purified extract at 100 mg (WBE111). One hundred and twenty-two older adults (65⁻80 years) were randomly allocated to a 6-month, daily regimen of either placebo or one of the three interventions. Participants were tested at baseline, 3, and 6 months on a battery of cognitive tasks targeting episodic memory, working memory and executive function, alongside mood and cardiovascular health parameters. Linear mixed model analysis found intervention to be a significant predictor of delayed word recognition on the Reys Auditory Verbal Learning Task (RAVLT), with simple contrast analysis revealing significantly better performance following WBE111 at 3 months. Similarly, performance on the Corsi Block task was predicted by treatment, with simple contrast analysis revealing a trend for better performance at 3 months following WBE111. Treatment also significantly predicted systolic blood pressure (SBP) with simple contrast analysis revealing lower SBP following interventionwith WBE111 in comparison to placebo. These results indicate 3 months intervention with WBE111 can facilitate better episodic memory performance in an elderly population and reduce cardiovascular risk factors over 6 months. <p><a href="https://greenmedinfo.com/article/blueberry-powder-could-can-facilitate-better-episodic-memory-performance-and-i" target="_blank">read more</a></p> https://greenmedinfo.com/article/blueberry-powder-could-can-facilitate-better-episodic-memory-performance-and-i#comments Aging: Brain Blueberry Memory Disorders Cardioprotective Neuroprotective Agents Human Study Sat, 28 Jul 2018 19:19:41 +0000 greenmedinfo 168140 at https://greenmedinfo.com A combination of phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine improves short term memory in aging beagles. https://greenmedinfo.com/article/combination-phosphatidylserine-ginkgo-biloba-vitamin-e-and-pyridoxine-improves PMID:  Can Vet J. 2008 Apr;49(4):379-85. PMID: 18481547 Abstract Title:  Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Abstract:  Aged dogs demonstrate cognitive decline that is linked to brain aging. The purpose of the present study was to examine if a commercially available nutraceutical supplement that may be neuroprotective and contains phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine could improve cognitive function in aged beagles. Nine aged beagles were tested on performance on a delayed-non-matching-to-position task, which is a neuropsychological test of short-term visuospatial memory. All subjects were tested on 5 baseline sessions; then, to assess the supplement, a crossover design was used in which 1 group received the supplement and the other a control substance in the 1st phase, with treatment conditions being reversed in the 2nd phase. Performance accuracy was significantly improved in supplemented dogs compared with control dogs and the effect was long lasting. These findings suggest that the nutraceutical supplement can improve memory in aged dogs. https://greenmedinfo.com/article/combination-phosphatidylserine-ginkgo-biloba-vitamin-e-and-pyridoxine-improves#comments Aging: Brain Ginkgo biloba Memory Disorders Phosphatidylserine Vitamin B-6 Vitamin E Plant Extracts Animal Study Sun, 21 Feb 2010 12:54:21 +0000 greenmedinfo 52175 at https://greenmedinfo.com