Early Onset GBS Disease (EOGBSD) https://greenmedinfo.com/taxonomy/term/49094/all en There is little (unbiased) clinical research to support the use of intrapartum antibiotics to reduce early onset GBS disease (EOGBSD). https://greenmedinfo.com/article/there-little-unbiased-clinical-research-support-use-intrapartum-antibiotics-re PMID:  Cochrane Database Syst Rev. 2009(3):CD007467. Epub 2009 Jul 8. PMID: 19588432 Abstract Title:  Intrapartum antibiotics for known maternal Group B streptococcal colonization. Abstract:  BACKGROUND: Maternal colonization with group B streptococcus (GBS) during pregnancy increases the risk of neonatal infection by vertical transmission. Administration of intrapartum antibiotic prophylaxis (IAP) during labor has been associated with a reduction in early onset GBS disease (EOGBSD). However, treating all colonized women during labor exposes a large number of women and infants to possible adverse effects without benefit.OBJECTIVES: To assess the effect of IAP for maternal GBS colonization on neonatal: 1) all cause mortality and 2) morbidity from proven and probable EOGBSD, late onset GBS disease (LOD), maternal infectious outcomes and allergic reactions to antibiotics.SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (April 2009).SELECTION CRITERIA: Randomized trials assessing the impact of maternal IAP on neonatal GBS infections were included.DATA COLLECTION AND ANALYSIS: We independently assessed eligibility and quality of the studies.MAIN RESULTS: Three trials (involving 852 women) evaluating the effects of IAP versus no treatment were included. The risk of bias was high. The use of IAP did not significantly reduce the incidence of all cause mortality, mortality from GBS infection or from infections caused by bacteria other than GBS. The incidence of early GBS infection was reduced with IAP compared to no treatment (risk ratio 0.17, 95% confidence interval (CI) 0.04 to 0.74, three trials, 488 infants; risk difference -0.04, 95% CI -0.07 to -0.01; number needed to treat to benefit 25, 95% CI 14 to 100, I(2) 0%). The incidence of LOD or sepsis from organisms other than GBS and puerperal infection was not significantly different between groups.One trial (involving 352 women) compared intrapartum ampicillin versus penicillin and reported no significant difference in neonatal or maternal outcomes.AUTHORS&#039; CONCLUSIONS: Intrapartum antibiotic prophylaxis appeared to reduce EOGBSD, but this result may well be a result of bias as we found a high risk of bias for one or more key domains in the study methodology and execution. There is lack of evidence from well designed and conducted trials to recommend IAP to reduce neonatal EOGBSD.Ideally the effectiveness of IAP to reduce neonatal GBS infections should be studied in adequately sized double-blind controlled trials. The opportunity to conduct such trials has likely been lost, as practice guidelines (albeit without good evidence) have been introduced in many jurisdictions. https://greenmedinfo.com/article/there-little-unbiased-clinical-research-support-use-intrapartum-antibiotics-re#comments Early Onset GBS Disease (EOGBSD) Neonatal Group B Streptococcal (GBS) Infections Streptococcus infections: Group B Antibiotics Meta Analysis Obstetric Intervention Sat, 29 Jan 2011 21:42:21 +0000 greenmedinfo 60600 at https://greenmedinfo.com Why Homebirth is 1,000 Times Safer Than Hospital Birth for Low Risk US Women https://greenmedinfo.com/blog/why-homebirth-1000-times-safer-hospital-birth-low-risk-us-women <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2020<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Why Homebirth is 1,000 Times Safer Than Hospital Birth for Low Risk US Women" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/home_birth_safer.jpg" style="width: 600px; height: 400px;" title="Why Homebirth is 1,000 Times Safer Than Hospital Birth for Low Risk US Women" /></p> <p><em><strong><span style="font-size:18px;">Why Homebirth is 1,000 Times Safer Than Hospital Birth for Low Risk US Women</span></strong></em></p> <p>Oft quoted research studies state 3X to 10X more babies die in the first week after low risk homebirth than hospital birth. In order for low risk homebirth to have higher perinatal mortality rates there would have to be a theory to explain this. There would have to be one or more complications of low risk homebirths that result in death in the first week that can be prevented by being in hospital, and death from these complications would have to occur more often than low risk deaths at planned hospital births.</p><p><a href="https://greenmedinfo.com/blog/why-homebirth-1000-times-safer-hospital-birth-low-risk-us-women" target="_blank">read more</a></p> https://greenmedinfo.com/blog/why-homebirth-1000-times-safer-hospital-birth-low-risk-us-women#comments Birth Problems: Breech Presentation Birth: Labor & Delivery Early Onset GBS Disease (EOGBSD) Neonatal Group B Streptococcal (GBS) Infections Pregnancy Complications Birth: Labor & Delivery Home Birth Home Birth Hospital Birth hospital versus homebirth is homebirth harmful? is homebirth safer? Midwifery Care Midwifery Care Natural Pregnancy children's health natural birth women's health Sat, 14 Dec 2013 02:50:13 +0000 judyslome 110740 at https://greenmedinfo.com