Hormone Replacement Therapy https://greenmedinfo.com/taxonomy/term/55704/all en 'Sunshine Vitamin' Regenerates and Detoxifies Your Hormones https://greenmedinfo.com/blog/sunshine-vitamin-regenerates-and-detoxifies-your-hormones <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2020<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Sunshine Vitamin Regenerates and Detoxifies Your Hormones" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/vitamin_detoxifies_regenerates_hormones(1).jpg" style="height: 600px; width: 600px;" /></p> <p><span style="font-size:18px;"><em><strong>Sometimes called the 'sunshine vitamin' because it is found in high levels in citrus fruits, vitamin C has a uniquely regenerative role in hormone health and cancer prevention that has been overlooked for over twenty years!</strong></em></span></p> <p>Truly groundbreaking research on the regenerative potential of vitamin C therapy for hormone health as well as cancer prevention was performed over twenty years ago, and yet still today it has received little to no attention. &nbsp;</p><p><a href="https://greenmedinfo.com/blog/sunshine-vitamin-regenerates-and-detoxifies-your-hormones" target="_blank">read more</a></p> https://greenmedinfo.com/blog/sunshine-vitamin-regenerates-and-detoxifies-your-hormones#comments Cancers: All Estrogen Deficiency Hormone Replacement Therapy Hormones: Insufficient Levels Progesterone: Low Testosterone: Too Low Vitamin C: Intravenous Cancer anticancer hormones vitamins Tue, 17 Dec 2019 18:02:37 +0000 Sayer Ji 116210 at https://greenmedinfo.com Hormone replacement therapy may have adverse effects in connection with prostate health such as accelerated aging. https://greenmedinfo.com/article/hormone-replacement-therapy-may-have-adverse-effects-connection-prostate-healt PMID:  Micron. 2011 Aug;42(6):642-55. Epub 2011 Apr 1. PMID: 21489806 Abstract Title:  Hormonal therapy in the senescence: Prostatic microenvironment structure and adhesion molecules. Abstract:  Hormonal replacement has been utilized to minimize the harmful effects of hormonal imbalance in elderly men. The development and progression of prostatic diseases and their relation to hormone therapy is still unclear. Thus, the aim herewith was to characterize the structure and dystroglycan molecule (DGs) reactivities in the ventral prostatic lobe from elderly rats submitted to steroid hormone replacement. Male rats (Sprague-Dawley) were divided into one Young group and six senile groups. The Young group (YNG) (4 months old) received peanut oil (5mL/kg, s.c.). The senile rats (10 months old) were submitted to the following treatments: Senile group (SEN) (5mL/kg peanut oil, s.c.); Testosterone group (TEST) (5mg/kg testosterone cipionate, s.c.); Estrogen group (EST) (25μg/kg 17β-estradiol, s.c.); Castrated group (CAS) (surgical castration); Castrated-Testosterone (CT) (surgical castration and treatment similar to TEST group); and Castrated-Estrogen (CE) (surgical castration and treatment similar to EST group). After 30 days treatment, blood samples were collected for hormonal analysis and ventral prostate samples were processed for light and transmission electron microscopies, morphometrical analysis, immunohistochemistry and Western Blotting. The results showed decreased serum testosterone levels in the senescence and increased testosterone and estrogen plasmatic levels after hormone administration in the TEST and EST groups, respectively, highlighting the therapy efficiency. Hypertrophied stroma and inflammatory cells were verified in the SEN group. After hormone replacement in the senescence or following castration, atrophic epithelium, epithelialcells with clear cytoplasmic halo around the nucleus, microacini and maintenance of hypertrophied stroma were seen. Decreased DG levels were verified in the senescence. After hormonal therapy, increased protein levels of these molecules were observed, especially in those groups which received estradiol. Thus, the occurrence of inflammatory cells, stromal hypertrophy and the presence of cells with clear halo around the nucleus after hormonal therapy probably indicated prostatic paracrine signaling imbalance, suggesting a stromal reactive microenvironment favorable to the development of glandular lesions. However, the increase of DG levels characterized positive effect of steroid hormone replacement on the prostate in the senescence. Thus, it could be concluded that despite having positive effects on important molecules involved in the maintenance of epithelial-stromal interaction and glandular cytoarchitecture, such as DGs, hormonal therapy enhanced structural changes associated with senescence, probably due to increased hormonal imbalance between androgens and estrogens in the prostatic tissue. https://greenmedinfo.com/article/hormone-replacement-therapy-may-have-adverse-effects-connection-prostate-healt#comments Aging Aging: Prostate Hormone Replacement Therapy Prostate Diseases Hormone Replacement Therapy Animal Study Thu, 26 May 2011 01:05:47 +0000 greenmedinfo 64218 at https://greenmedinfo.com Resveratrol may reduce the pro-coagulant adverse effects associated with high estrogen conditions. https://greenmedinfo.com/article/resveratrol-may-reduce-pro-coagulant-adverse-effects-associated-high-estrogen- PMID:  Thromb Res. 2011 Jan;127(1):e1-7. PMID: 20926118 Abstract Title:  Resveratrol, a phytoestrogen found in red wine, down-regulates protein S expression in HepG2 cells. Abstract:  UNLABELLED: INTRODUATION: Resveratrol, a phytoestrogen present at a high concentration in red wine, has been reported to possess many health benefit effects that are protective against age-related diseases. Protein S (PS), an important anticoagulant factor in the protein C (PC) anticoagulant pathway, is mainly synthesized by hepatocytes, and its plasma level is decreased in high-estrogen conditions such as pregnancy and oral contraceptive use. The aim of this study was to investigate whether resveratrol affects PS expression in HepG2 cells.MATERIALS AND METHODS: The secreted and intracellular levels of PS were determined by an enzyme-linked ligandsorbent assay and Western blotting. The mRNA expressions of PS, PC andβ chain of C4b-binding protein (C4BP-β) were analyzed by reverse transcription-polymerase chain reaction. The PS gene promotor activities in HepG2 cells transiently expressing estrogen receptor (ER) α were examined by a luciferase reporter assay.RESULTS: Resveratrol dose- and time-dependently down-regulated the PS expression in HepG2 cells at a transcriptional level, resulting in a significant decrease in secreted PS; however, the PC and C4BP-β mRNA expressions were not affected. This action of resveratrol was not mediated through either the ER signaling or those of mitogen-activated protein kinases and protein kinase C. Piceatannol, a hydroxylated metabolite of resveratrol, and genistein, an isoflavone found in soy products, also down-regulated the PS expression.CONCLUSIONS: Resveratrol down-regulates the PS expression in HepG2 cells in an ER-independent manner, and the two phenolic hydroxyls at carbon-3 and -5 of resveratrol may be involved in this function. https://greenmedinfo.com/article/resveratrol-may-reduce-pro-coagulant-adverse-effects-associated-high-estrogen-#comments Contraception Estrogen Dominance Hormone Replacement Therapy Resveratrol Thrombosis Anti-thrombotic In Vitro Study Fri, 11 Mar 2011 00:49:46 +0000 greenmedinfo 62497 at https://greenmedinfo.com Soy isoflavones compare favorably and works synergistically with estrogen in rectifying estrogen deficiency associated with ovariectomy. https://greenmedinfo.com/article/soy-isoflavones-compare-favorably-and-works-synergistically-estrogen-rectifyin PMID:  Pathol Res Pract. 2011 May 15;207(5):300-5. Epub 2011 Apr 21. PMID: 21514062 Abstract Title:  Effect of estrogen therapy, soy isoflavones, and the combination therapy on the submandibular gland of ovariectomized rats. Abstract:  The objective of this study was to evaluate the effect of estrogen deficiency, estrogen therapy, and soy isoflavones on the salivary glands in female rats. Ninety-six animals were ovariectomized, and 24 were sham-operated. Among the ovariectomized rats, 24 received 17β-estradiol; 24 received isoflavone extract; 24 received a combination therapy of both; and 24 received water as placebo. The submandibular glands were histomorphometrically analyzed. As a result, the ANOVA test revealed that the hormonal deficiency affected the acini and the ducts of ovariectomized rats, reducing their percentage compared to the sham group. All treatments caused an increase in ducts and acini compared to the placebo group. It was concluded that the estrogen deficiency may be related to salivary gland function due to a reduction in the quantity of salivary acini and ducts secondary to ovariectomy. The estrogen therapy, soy isoflavone therapy, and the combination of both are effective in reducing the effects of ovariectomy on the salivary glands. https://greenmedinfo.com/article/soy-isoflavones-compare-favorably-and-works-synergistically-estrogen-rectifyin#comments Estradiol (E(2)) Estrogen Deficiency Hormone Replacement Therapy Isoflavones Postmenopausal Disorders Soy Ovariectomy-Induced Changes Animal Study Thu, 26 May 2011 18:06:54 +0000 greenmedinfo 64232 at https://greenmedinfo.com