Cancers: Radiation-Induced https://greenmedinfo.com/taxonomy/term/56593/all en It has been estimated that about 0.4% of all cancers in the United States may be attributable to the radiation from CT studies. https://greenmedinfo.com/article/it-has-been-estimated-about-04-all-cancers-united-states-may-be-attributable-r PMID:  N Engl J Med. 2007 Nov 29;357(22):2277-84. PMID: 18046031 Abstract Title:  Computed tomography--an increasing source of radiation exposure. Abstract:  Excerpts: &quot;The widespread use of CT represents probably the single most important advance in diagnostic radiology. However, as compared with plain-film radiography, CT involves much higher doses of radiation, resulting in a marked increase in radiation exposure in the population. The increase in CT use and in the CT-derived radiation dose in the population is occurring just as our understanding of the carcinogenic potential of low doses of x-ray radiation has improved substantially, particularly for children. This improved confidence in our understanding of the lifetime cancer risks from low doses of ionizing radiation has come about largely because of the length of follow-up of the atomic-bomb survivors — now more than 50 years — and because of the consistency of the risk estimates with those from other large-scale epidemiologic studies. These considerations suggest that the estimated risks associated with CT are not hypothetical — that is, they are not based on models or major extrapolations in dose. Rather, they are based directly on measured excess radiation-related cancer rates among adults and children who in the past were exposed to the same range of organ doses as those delivered during CT studies....It has been estimated that about 0.4% of all cancers in the United States may be attributable to the radiation from CT studies.&quot; View entire free article here. https://greenmedinfo.com/article/it-has-been-estimated-about-04-all-cancers-united-states-may-be-attributable-r#comments Cancers: All Cancers: Radiation-Induced Carcinogens Computed tomography (CT) Scan Review Sun, 20 Mar 2011 17:51:53 +0000 greenmedinfo 62719 at https://greenmedinfo.com Chemo and Radiation Can Make Cancer More Malignant https://greenmedinfo.com/blog/does-chemo-radiation-actually-make-cancer-more-malignant <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2018<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Chemo and Radiation Actually Make Cancer More Malignant" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/sayerji/images/k-age.jpg" style="width: 400px; height: 259px;" /></p> <p><span style="font-size:22px;"><em><strong>Cancer is the second leading cause of death in the developed world, and yet we are still in the dark ages when it comes to treating and understanding it.</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/does-chemo-radiation-actually-make-cancer-more-malignant" target="_blank">read more</a></p> https://greenmedinfo.com/blog/does-chemo-radiation-actually-make-cancer-more-malignant#comments All-Cause Mortality Auricular Cancer Bile Duct Cancer Bladder Cancer Breast Cancer Cancer Patients Cancers: All Cancers: Canine Cancers: Drug Resistant Cancers: Radiation-Induced Colon Cancer Lung Cancer Cancer Health Guide: Breast Cancer Tue, 31 Jul 2012 16:35:52 +0000 Sayer Ji 73384 at https://greenmedinfo.com Hell Hole on Earth Discovered at Fukushima https://greenmedinfo.com/blog/hell-hole-earth-discovered-fukushima <p class="rtecenter"><img alt="Hell Hole on Earth Discovered at Fukushima" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/fukushima_hell_hole_greenmedinfo(1).jpg" style="width: 650px; height: 379px;" title="Hell Hole on Earth Discovered at Fukushima" /></p> <p class="rtecenter">Originally published on <strong><a href="http://drsircus.com/general/hell-hole-earth-discovered-fukushima/" target="_blank" title="Hell Hole on Earth Discovered at Fukushima">DrSircus.com</a></strong>.</p> <p><span style="font-size:18px;"><em><strong>Most people think they have to die to go to hell but that is not true anymore. Today, in the mainstream press, they announced the existence of a hell hole in Japan at the destroyed nuclear power station at Fukushima. We have a hot spot on our planet that has never been imagined before and in the face of it human technology is helpless.</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/hell-hole-earth-discovered-fukushima" target="_blank">read more</a></p> https://greenmedinfo.com/blog/hell-hole-earth-discovered-fukushima#comments Cancers: All Cancers: Radiation-Induced Carcinogenic Nuclear Reactor Radiation Cancer Hell Hole on Earth Discovered at Fukushima nuclear power radiation Mon, 13 Feb 2017 16:34:56 +0000 drsircus 143410 at https://greenmedinfo.com Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. https://greenmedinfo.com/article/infradiaphragmatic-irradiation-and-high-procarbazine-doses-increase-colorectal PMID:  Br J Cancer. 2017 Jul 25 ;117(3):306-314. Epub 2017 Jun 20. PMID: 28632726 Abstract Title:  Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. Abstract:  BACKGROUND: Hodgkin lymphoma (HL) survivors are at increased risk of second malignancies, but few studies have assessed colorectal cancer (CRC) risk after HL treatment. We assessed long-term, subsite-specific CRC risk associated with specific radiation fields and chemotherapy regimens.METHODS: In a Dutch cohort of 3121 5-year HL survivors treated between 1965 and 1995, subsite-specific CRC incidence was compared with general population rates. Treatment effects were quantified by Cox regression analyses.RESULTS: After a median follow-up of 22.9 years, 55 patients developed CRC. The standardized incidence ratios (SIR) was 2.4-fold increased (95% confidence interval (95%CI) 1.8-3.2), leading to 5.7 excess cases per 10 000 patient-years. Risk was still increased 30 years after HL treatment (SIR: 2.8; 95%CI: 1.6-4.6). The highest (SIR: 6.5, 95%CI: 3.3-11.3) was seen for transverse colon cancer (15.0 (95%CI: 4.3-40.8) after inverted-Y irradiation). A prescribed cumulative procarbazine dose&gt;4.2 g m(-2) was associated with a 3.3-fold higher CRC risk (95%CI: 1.8-6.1) compared to treatment without procarbazine. Patients receiving&gt;4.2 g m(-2) procarbazine and infradiaphragmatic radiotherapy had a hazard ratio of 6.8 (95%CI: 3.0-15.6) compared with patients receiving neither treatment, which is significantly higher than an additive joint effect (Padditivity=0.004).CONCLUSIONS: Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose. <p><a href="https://greenmedinfo.com/article/infradiaphragmatic-irradiation-and-high-procarbazine-doses-increase-colorectal" target="_blank">read more</a></p> https://greenmedinfo.com/article/infradiaphragmatic-irradiation-and-high-procarbazine-doses-increase-colorectal#comments Cancers: Radiation-Induced Chemotherapy and Radiation Toxicity Human Study Tue, 08 Aug 2017 21:23:44 +0000 greenmedinfo 151360 at https://greenmedinfo.com Meadowsweet preparation showed inhibiting activity on radiation carcinogenesis. https://greenmedinfo.com/article/meadowsweet-preparation-showed-inhibiting-activity-radiation-carcinogenesis PMID:  Int J Radiat Biol. 2016 Nov 9:1-29. Epub 2016 Aug 9. PMID: 27827272 Abstract Title:  The inhibitory effect of meadowsweet (Filipendula ulmaria) on radiation-induced carcinogenesis in rats. Abstract:  PURPOSE: To examine the ability of the meadowsweet preparation to inhibit carcinogenesis induced by ionizing radiation in female rats.MATERIALS AND METHODS: The chemical composition of meadowsweet (Filipendula ulmaria) raw material (ethanol and aqueous extracts of meadowsweet flowers) has been studied for the presence of flavonoids, tannins and catechins. In animal experiments adult female LIO strain rats were subjected to a single whole bodyγ-irradiation at a dose of 4 Gy. One group of irradiated rats served as control while the other group, starting from the 10th day after irradiation and until the end of the experiment, was given meadowsweet as a decoction of the flowers instead of drinking water. The average daily intake of meadowsweet (dry raw material) was 1 g/kg body weight. Rats were observed for 16 months.RESULTS: The analyzed meadowsweet extracts showed a sufficiently high content of flavonoids and tannins. In irradiated rats after 16 months the overall incidence of tumors was 79.6% (in 82 of 103 rats), the incidence of malignant tumors was 43.7% and the overall tumor multiplicity was 1.48. Most tumors were localized in the mammary gland - 57.3%. In rats that received meadowsweet, the incidence of all malignant tumors and overall multiplicity of tumors were significantly decreased by 1.5 and 1.3 times, respectively. The greatest reduction of many parameters has been identified for breast tumors: the overall incidence was decreased by 1.5 (p = 0.0174) and the overall multiplicity and multiplicity of malignant tumors - by 1.6 (p = 0.0002) and 2.2 (p = 0.0383) times, respectively.CONCLUSIONS: Meadowsweet preparation showed inhibiting activity on radiation carcinogenesis. <p><a href="https://greenmedinfo.com/article/meadowsweet-preparation-showed-inhibiting-activity-radiation-carcinogenesis" target="_blank">read more</a></p> https://greenmedinfo.com/article/meadowsweet-preparation-showed-inhibiting-activity-radiation-carcinogenesis#comments Breast Cancer Cancers: Radiation-Induced Meadowsweet Anticarcinogenic Agents Radioprotective Plant Extracts Animal Study Mon, 14 Nov 2016 18:30:30 +0000 greenmedinfo 139073 at https://greenmedinfo.com New Study Shows Full Radiation Risks Are Not Recorded https://greenmedinfo.com/blog/new-study-shows-full-radiation-risks-are-not-recorded <p class="rtecenter"><img alt="New Study Shows Full Radiation Risks are not Recorded " src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/radioactivity_fukushima_greenmedinfo.jpg" style="width: 700px; height: 538px;" /></p> <p><strong><span style="font-size:18px;"><em>Based on 415 samples of radioactive dust from Japan, the USA, and Canada, a study identified a statistically meaningful number of samples that were considerably more radioactive than current radiation models anticipated.</em></span><br /> &nbsp;</strong><br /> <img alt="New Study Shows Full Radiation Risks are not Recorded " src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/Fairewinds_Logo.png" style="width: 350px; height: 84px;" /></p> <h2> <strong>PRESS RELEASE -&nbsp;<span data-term="goog_920932753" tabindex="0">7/27/17</span>&nbsp;</strong></h2> <p><strong>Contact:&nbsp;<a href="mailto:info@fairewindsenergy.org" target="_blank">info@fairewindsenergy.org</a></strong></p><p><a href="https://greenmedinfo.com/blog/new-study-shows-full-radiation-risks-are-not-recorded" target="_blank">read more</a></p> https://greenmedinfo.com/blog/new-study-shows-full-radiation-risks-are-not-recorded#comments Cancers: All Cancers: Radiation-Induced Carcinogenic Nuclear Reactor Radiation Thu, 27 Jul 2017 18:39:51 +0000 fairewindsenergy 150883 at https://greenmedinfo.com Nigella sativa oil (NSO) and its active component, TQ, clearly protect brain tissue from radiation-induced nitrosative stress. https://greenmedinfo.com/article/nigella-sativa-oil-nso-and-its-active-component-tq-clearly-protect-brain-tissu PMID:  Phytomedicine. 2013 Nov 21. pii: S0944-7113(13)00432-7. doi: 10.1016/j.phymed.2013.10.023. [Epub ahead of print] Abstract Title:  Radiation-modifying abilities of Nigella sativa and Thymoquinone on radiation-induced nitrosative stress in the brain tissue. Abstract:  To investigate Nigella sativa oil (NSO) and Thymoquinone (TQ) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation. Fifty-four male albino Wistar rats, divided into six groups, were designed as group I (normal control group) did not receive NSO, TQ or irradiation; group II (control group of TQ) received dimethyl sulfoxide and sham irradiation; group III (control group of NSO) received saline and sham irradiation; group IV (irradiation plus NSO group) received both 5 Gray of gamma irradiation to total cranium and NSO; group V (irradiation plus TQ group) received both irradiation and TQ; group VI (irradiation alone group) received irradiation plus saline. Alterations in nitric oxide (NO) and peroxynitrite (ONOO(-)) levels, and nitric oxide synthase (NOS) enzyme activity were measured by biochemical methods in homogenized brain tissue of rats. Levels of NO and ONOO(-), and enzyme activity of NOS in brain tissue of the rats treated with NSO or TQ were found to be lower than in received IR alone (p https://greenmedinfo.com/article/nigella-sativa-oil-nso-and-its-active-component-tq-clearly-protect-brain-tissu#comments Cancers: Radiation-Induced Chemotherapy and Radiation Toxicity Nigella sativa (aka Black Seed) Thymoquinone Radioprotective Animal Study Thu, 28 Nov 2013 18:34:01 +0000 greenmedinfo 110583 at https://greenmedinfo.com Radiation-induced inflammatory cascade and its reverberating crosstalks as potential cause of post-radiotherapy second malignancies. https://greenmedinfo.com/article/radiation-induced-inflammatory-cascade-and-its-reverberating-crosstalks-potent PMID:  Cancer Metastasis Rev. 2017 Jul 13. Epub 2017 Jul 13. PMID: 28707199 Abstract Title:  Radiation-induced inflammatory cascade and its reverberating crosstalks as potential cause of post-radiotherapy second malignancies. Abstract:  The disease-free survival following radiotherapy is often limited by the development of second/secondary cancers. This significant impediment to effective cancer treatment implicated even in the modern-day radiotherapy needs to be countered effectively. Critical analysis reveals that besides achieving effective tumor control, radiotherapy elicits certain cellular and systemic inflammatory events in tumor infiltrate, which remain relatively stable and tend to facilitate&quot;in-field&quot;or&quot;out of field&quot;oncogenesis in due course of time. Acute pro-inflammatory cytokines generated as a result of radiation-induced oxidative insult and DNA damage induce genetic instability that contributes to tumor heterogeneity and plasticity. The reverberating crosstalks between radiation-targeted tumor and its microenvironment in turn initiate inflammatory loops that feedback the immune system to manifest as systemic consequences. An&quot;inflammatory switchover&quot;within the tumor microenvironment is thus induced by cumulative radiation exposure, initiating pro-tumor events that can severely limit the outcome of radiotherapy. Various pro-survival tumorigenic pathways activated as a result regulate radiation-induced hypoxia, ECM remodeling, angiogenesis/vasculogenesis, and immune suppression/evasion within the tumor microenvironment. NF-κB, HIF and STAT are identified as central regulating mediators among others that orchestrate inflammatory switchover from apoptosis-mediated tumor surveillance to radiation-induced carcinogenesis. Radiation-induced interleukins stimulate recruited macrophages and endothelial cells to promote intravasation, which is further aided by release of chemokines favoring extravasation and secondary site lesions. We hence propose that delineating the inflammatory signaling network emanating from irradiation of complex tumor tissue is critical for devising suitable therapeutic strategies to prevent post-radiotherapy second cancers or metastasis. Graphical Abstract ᅟ. <p><a href="https://greenmedinfo.com/article/radiation-induced-inflammatory-cascade-and-its-reverberating-crosstalks-potent" target="_blank">read more</a></p> https://greenmedinfo.com/article/radiation-induced-inflammatory-cascade-and-its-reverberating-crosstalks-potent#comments Cancers: Radiation-Induced Radiotherapy Risk Factors Review Tue, 08 Aug 2017 21:01:56 +0000 greenmedinfo 151357 at https://greenmedinfo.com Radiotherapy may confer greater aggressiveness to breast cancer stem cells, resulting in recurrence. https://greenmedinfo.com/article/radiotherapy-may-confer-greater-aggressiveness-breast-cancer-stem-cells-result PMID:  Oncogene. 2012 Feb 13. Epub 2012 Feb 13. PMID: 22330142 Abstract Title:  CD24(-/low) stem-like breast cancer marker defines the radiation-resistant cells involved in memorization and transmission of radiation-induced genomic instability. Abstract:  A growing body of evidence attributes properties of chemo- and/or radiation-resistance to cancer stem cells (CSCs). Moreover, non-targeted delayed effects such as genomic instability, transmitted through many generations, can be observed in the progeny of surviving irradiated cells. As a consequence, we propose that radiation-resistance properties associated to CSCs could confer a key role to this subpopulation in the transmission of genomic instability. To test this hypothesis, we searched the CSC markers associated to radiation-resistance in breast cancer cell lines and studied the role of the resistant cells in the transmission of genomic instability. First, we show that irradiation induces a 2-4 weeks period of intense cell death leading to the emergence of chromosomal unstable cells during more than 35 population doublings. Then, among seven breast CSC markers, we identify CD24(-/low) labelling as a marker of radiation-resistance. We demonstrate that CD24(+) progeny of irradiated cells exclusively descends from CD24(-/low) cells. Finally, we show that delayed chromosomal instability is only expressed by CD24(+) cells, but is transmitted by stable surviving CD24(-/low) cells. So, for the first time a CSC marker, CD24, is associated with the transmission of genomic instability. This work may assign a new deleterious role to breast CSCs in aggressive recurrence after radiotherapy, as the transmitted genomic instability potentially leads tumour cells to acquire more aggressive characteristics.Oncogene advance online publication, 13 February 2012; doi:10.1038/onc.2012.31. https://greenmedinfo.com/article/radiotherapy-may-confer-greater-aggressiveness-breast-cancer-stem-cells-result#comments Breast Cancer Stem Cells Cancer Stem Cells Cancers: Radiation-Induced Cancers: Radiation-Resistant Radiotherapy Tumorigenic In Vitro Study Tue, 17 Jul 2012 16:51:41 +0000 greenmedinfo 78632 at https://greenmedinfo.com Radiotherapy may result in the enrichment of highly malingant cancer stem cells in breast cancer patients. https://greenmedinfo.com/article/radiotherapy-may-result-enrichment-highly-malingant-cancer-stem-cells-breast-c PMID:  Transl Oncol. 2011 Aug ;4(4):227-33. Epub 2011 Aug 1. PMID: 21804918 Abstract Title:  Ablation of breast cancer stem cells with radiation. Abstract:  Tumor radioresistance leads to recurrence after radiation therapy. The radioresistant phenotype has been hypothesized to reside in the cancer stem cell (CSC) component of breast and other tumors and is considered to be an inherent property of CSC. In this study, we assessed the radiation resistance of breast CSCs using early passaged, patient-derived xenografts from two separate patients. We found a patient-derived tumor in which the CSC population was rapidly depleted 2 weeks after treatment with radiation, based on CD44(+) CD24(-) lin(-) phenotype and aldehyde dehydrogenase 1 immunofluorescence, suggesting sensitivity to radiotherapy. The reduction in CSCs according to phenotypic markers was accompanied by a decrease in functional CSC activity measured by tumor sphere frequency and the ability to form tumors in mice. In contrast, another patient tumor sample displayed enrichment of CSC after irradiation, signifying radioresistance, in agreement with others. CSC response to radiation did not correlate with the level of reactive oxygen species in CSC versus non-CSC. These findings demonstrate that not all breast tumor CSCs are radioresistant and suggest a mechanism for the observed variability in breast cancer local recurrence. https://greenmedinfo.com/article/radiotherapy-may-result-enrichment-highly-malingant-cancer-stem-cells-breast-c#comments Breast Cancer Stem Cells Cancer Stem Cells Cancers: Radiation-Induced Cancers: Radiation-Resistant Radiotherapy Tumorigenic Review Tue, 17 Jul 2012 17:05:33 +0000 greenmedinfo 78636 at https://greenmedinfo.com Stem-cell division is a key mechanism behind tumour re-population; the stem-cell cycle time can drop below 10 h during radiotherapy. https://greenmedinfo.com/article/stem-cell-division-key-mechanism-behind-tumour-re-population-stem-cell-cycle-t PMID:  Cell Prolif. 2012 Jul 7. Epub 2012 Jul 7. PMID: 22775509 Abstract Title:  Influence of stem-cell cycle time on accelerated re-population during radiotherapy in head and neck cancer. Abstract:  OBJECTIVES: Tumour re-population during radiotherapy was identified as an important reason for treatment failure in head and neck cancers. The process of re-population is suggested to be caused by various mechanisms, one of the most plausible one being accelerated division of stem-cells (i.e. drastic shortening of cell cycle duration). However, the literature lacks quantitative data regarding the length of tumour stem-cell cycle time during irradiation. MATERIALS AND METHODS: The presented work suggests that if accelerated stem-cell division is indeed a key mechanism behind tumour re-population, the stem-cell cycle time can drop below 10 h during radiotherapy. To illustrate the possible implications, the mechanism of accelerated division was implemented into a Monte Carlo model of tumour growth and response to radiotherapy. Tumour response to radiotherapy was simulated with different stem-cell cycle times (between 2 and 10 h) after the initiation of radiotherapy. RESULTS: It was found that very short stem-cell cycle times lead to tumour re-population during treatment, which cannot be overcome by radiation-induced cell kill. Increasing the number of radiation dose fractions per week might be effective, but only for longer cell cycle times. CONCLUSION: It is of crucial importance to quantitatively assess the mechanisms responsible for tumour re-population, given that conventional treatment regimens are not efficient in delivering lethal doses to advanced head and neck tumours. https://greenmedinfo.com/article/stem-cell-division-key-mechanism-behind-tumour-re-population-stem-cell-cycle-t#comments Cancer Stem Cells Cancers: Radiation-Induced Carcinogenic Radiotherapy Tumorigenic Cancer Stem Cells In Vitro Study Tue, 17 Jul 2012 16:43:38 +0000 greenmedinfo 78631 at https://greenmedinfo.com Tangeretin almost completely inhibited lung metastasis induced by irradiation in this study. https://greenmedinfo.com/article/tangeretin-almost-completely-inhibited-lung-metastasis-induced-irradiation-stu PMID:  Oncol Rep. 2015 May 15. Epub 2015 May 15. PMID: 25998143 Abstract Title:  Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Abstract:  Irradiation has been reported to increase radioresistance and epithelial-mesenchymal transition (EMT) in gastric cancer (GC) cells. The Notch pathway is critically implicated in cancer EMT and radioresistance. In the present study, we investigated the use of a Notch-1 inhibiting compound as a novel therapeutic candidate to regulate radiation-induced EMT in GC cells. According to previous screening, tangeretin, a polymethoxylated flavonoid from citrus fruits was selected as a Notch-1 inhibitor. Tangeretin enhanced the radiosensitivity of GC cells as demonstrated by MTT and colony formation assays. Tangeretin also attenuated radiation-induced EMT, invasion and migration in GC cells, accompanied by a decrease in Notch-1, Jagged1/2, Hey-1 and Hes-1 expressions. Tangeretin triggered the upregulation of miR-410, a tumor-suppressive microRNA. Furthermore, re-expression of miR-410 prevented radiation-induced EMT and cell invasion. An in vivo tumor xenograft model confirmed the antimetastasis effect of tangeretin as we observed in vitro. In nude mice, tumor size was considerably diminished by radiation plus tangeretin co-treatment. Tangeretin almost completely inhibited lung metastasis induced by irradiation. Tangeretin may be anovel antimetastatic agent for radiotherapy. https://greenmedinfo.com/article/tangeretin-almost-completely-inhibited-lung-metastasis-induced-irradiation-stu#comments Cancers: Radiation-Induced Gastric Cancer Tangeretin Anti-metastatic MicroRNA modulator Radioprotective Radiosensitizer Significant Treatment Outcome Animal Study In Vitro Study Thu, 28 May 2015 01:43:07 +0000 greenmedinfo 117789 at https://greenmedinfo.com There is a concerning association between heavy mobile phone use and brain tumours. https://greenmedinfo.com/article/there-concerning-association-between-heavy-mobile-phone-use-and-brain-tumours n/a PMID:  Occup Environ Med. 2014 Jul ;71(7):514-22. Epub 2014 May 9. PMID: 24816517 Abstract Title:  Mobile phone use and brain tumours in the CERENAT case-control study. Abstract:  UNLABELLED: The carcinogenic effect of radiofrequency electromagnetic fields in humans remains controversial. However, it has been suggested that they could be involved in the aetiology of some types of brain tumours. OBJECTIVES: The objective was to analyse the association between mobile phone exposure and primary central nervous system tumours (gliomas and meningiomas) in adults. METHODS: CERENAT is a multicenter case-control study carried out in four areas in France in 2004-2006. Data about mobile phone use were collected through a detailed questionnaire delivered in a face-to-face manner. Conditional logistic regression for matched sets was used to estimate adjusted ORs and 95% CIs. RESULTS: A total of 253 gliomas, 194 meningiomas and 892 matched controls selected from the local electoral rolls were analysed. No association with brain tumours was observed when comparing regular mobile phone users with non-users (OR=1.24; 95% CI 0.86 to 1.77 for gliomas, OR=0.90; 95% CI 0.61 to 1.34 for meningiomas). However, the positive association was statistically significant in the heaviest users when considering life-long cumulative duration (≥896 h, OR=2.89; 95% CI 1.41 to 5.93 for gliomas; OR=2.57; 95% CI 1.02 to 6.44 for meningiomas) and number of calls for gliomas (≥18,360 calls, OR=2.10, 95% CI 1.03 to 4.31). Risks were higher for gliomas, temporal tumours, occupational and urban mobile phone use. CONCLUSIONS: These additional data support previous findings concerning a possible association between heavy mobile phone use and brain tumours. https://greenmedinfo.com/article/there-concerning-association-between-heavy-mobile-phone-use-and-brain-tumours#comments Brain Cancer Cancers: Radiation-Induced Carcinogenic (suspected) Cell Phone Exposure Electromagnetic Field Harms Electromagnetic Radiation Microwave Radiation Mobile Phone Radiation Cell Phones Cellular Phones and Cancers electromagnetic fields electromagnetic frequencies electromagnetic radiation EMF Radio Frequency Electromagnetic Radiation Exposure Human Study Sat, 03 Aug 2019 14:11:02 +0000 greenmedinfo 192770 at https://greenmedinfo.com This article focuses on radiation-induced malignancies with illustrative cases of thyroid, rectal cancer and sarcoma. https://greenmedinfo.com/article/article-focuses-radiation-induced-malignancies-illustrative-cases-thyroid-rect PMID:  Anticancer Res. 2015 Apr ;35(4):2431-4. PMID: 25862910 Abstract Title:  Radiation-induced Second Malignancies. Abstract:  BACKGROUND: The number of patients with second malignancies is growing and they represent about one in six out of all new cancers. Second malignancies can be categorized into three major groups according to the predominant etiological factor(s): (i) treatment-related, (ii) part of a syndrome and (iii) those due to shared etiologic exposures.PATIENTS AND METHODS: This article focuses on radiation-induced malignancies with illustrative cases of thyroid, rectal cancer and sarcoma.RESULTS: The detection and management of radiation-induced malignancies of some case scenarios are presented. Second malignancies are detected within previous radiation field and the time intervals from previous tumor vary from 8 to 21 years.CONCLUSION: Clinicians should aim to reduce radiation-induced malignancies by careful selection of patients and radiation techniques before radiotherapy. Subsequent vigilant follow-up and investigations can detect these radiation-induced malignancies early and, hence, result in successful treatment. https://greenmedinfo.com/article/article-focuses-radiation-induced-malignancies-illustrative-cases-thyroid-rect#comments Cancers: Radiation-Induced Rectal Cancer Sarcoma Thyroid Cancer Carcinogenic Radiotherapy Review Sun, 19 Apr 2015 23:36:06 +0000 greenmedinfo 116943 at https://greenmedinfo.com Why Mammography Is Unscientific And Harmful https://greenmedinfo.com/blog/why-mammography-unscientific-and-harmful <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2017<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Why Mammography Is Unscientific And Harmful" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/radiation_breast.png" /></p> <p>Getting a mammogram seems like a "no-brainer." The diagnostic test detects, by emitting allegedly harmless ionizing radiation, breast cancer early, thus it prevents the premature demise of the patient. Yet, many solid scientific facts invalidate these, on the surface, seemingly legitimate, highly plausible notions or claims about the value of mammography.</p> <h1> <span style="font-size:16px;"><strong>Some "Inconvenient" Facts Women Should Know About Mammography</strong></span></h1> <blockquote> <p><em><strong>"The interaction with the unaccountable, self-regulating business called "modern medicine" is analogous to buying a used car from a stranger: you never really know what you're getting because of the things you're not being told. And what is not being disclosed can (seriously) hurt you." </strong></em></p><p><a href="https://greenmedinfo.com/blog/why-mammography-unscientific-and-harmful" target="_blank">read more</a></p> https://greenmedinfo.com/blog/why-mammography-unscientific-and-harmful#comments Breast Cancer Breast Cancer: Prevention Cancers: Radiation-Induced Radation Exposure: Low-Dose Radiotherapy X-ray Mammography X-ray Mammography: Digital Wed, 28 Aug 2013 12:40:52 +0000 rolfhefti 109570 at https://greenmedinfo.com