Placental abruption https://greenmedinfo.com/taxonomy/term/59026/all en Hyperhomocysteinaemia, vascular related pregnancy complications respond favorably to vitamin supplementation in pregnant women of Pakistan. https://greenmedinfo.com/article/hyperhomocysteinaemia-vascular-related-pregnancy-complications-respond-favorab PMID:  J Pak Med Assoc. 2010 Sep;60(9):741-5. PMID: 21381582 Abstract Title:  Hyperhomocysteinaemia, vascular related pregnancy complications and the response to vitamin supplementation in pregnant women of Pakistan. Abstract:  OBJECTIVES: To elaborate the relationship between serum homocysteine (hcy) levels and vascular related pregnancy complications in pregnant women as well as to assess the homocysteine lowering effects of folate, vitamin 812 and 86. The secondary objectives were to establish a link between serum homocysteine levels and maternal age, parity, gestational age, foetal birth weight, mean arterial pressure and albuminuria.METHODS: A total of 332 pregnant women (gestational age:>24 weeks) attending Liaquat University Hospital Hyderabad, Pakistan, were enrolled. Of these 112 were healthy normal pregnant women; 61 pregnant women had pre-eclampsia, 49 with eclampsia and 110 with placental abruption. A cohort of 30 patients with elevated hcy levels (>8.2 micromol/liter), were given folate, vitamin B12 and B6 as supplements for 6 weeks. Fasting blood samples were collected, centrifuged and stored at 2 to 8 degrees C. Hcy levels were determined by IMx immunoassay.RESULTS: Higher serum hcy levels, higher mean arterial blood pressure (MAP), pre-term deliveries and low foetal birth weights were noted in women with pregnancies complicated by pre-eclampsia and eclampsia as compared to control and those with placental abruption. Significant hcy lowering effects of folate, vitamin 812 and B6 supplementation were observed. Significant and positive correlation was found between hhcy and MAP (r = 0.001; p https://greenmedinfo.com/article/hyperhomocysteinaemia-vascular-related-pregnancy-complications-respond-favorab#comments Albuminuria: Pregnancy-Associated B-complex Eclampsia High Homocysteine Infants: Low Birth Weight Placental abruption Pre-Eclampsia Pregnancy Complications Vitamin B-12 Vitamin B-6 Human Study Fri, 29 Apr 2011 23:42:11 +0000 greenmedinfo 63460 at https://greenmedinfo.com