Parkinson&#039;s disease https://greenmedinfo.com/category/keywords/parkinsons-disease en 8 Healing Properties of Strawberries https://greenmedinfo.com/blog/8-healing-properties-strawberries <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2023<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="8 Juicy Reasons to Eat More Strawberries" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/Strawberries1.jpg" style="width: 500px; height: 333px;" /></p> <p><strong><span style="font-size:18px;"><em>Who doesn't love <a href="/substance/strawberry" rel="dofollow" target="_blank">strawberries</a>? And you don't need any reason other than the pleasure of their sweetness to eat them every day. But according to researchers from Oklahoma State University, there's lots more to strawberries than the flavor.</em></span><a href="#_edn1" name="_ednref1" title="">[i]</a></strong></p> <p>Their study was <strong><a href="https://www.ncbi.nlm.nih.gov/pubmed/24345049" rel="nofollow" target="_blank">published in the journal <em>Critical Reviews in Food Science and Nutrition</em></a></strong> with funding from the NIH and the California Strawberry Commission. In it the researchers review over 130 studies attesting to the strawberry's status as a "functional food."</p><p><a href="https://greenmedinfo.com/blog/8-healing-properties-strawberries" target="_blank">read more</a></p> https://greenmedinfo.com/blog/8-healing-properties-strawberries#comments Alzheimer's Disease Anthocyanins Blackberry C-Reactive Protein (CRP) Cancer Cardiovascular Diseases Carotenoids Catechin Ellagic Acid Flavonoids Hyperglycemia Hyperlipidemia Hypertension Kaempferol Naringenin Parkinson's Disease Phytosterols Polyphenols Potassium Quercetin Strawberry Vitamin C Vitamin E Antioxidants Health Guide: Farm/Pharma Face Off Health Guides: Healing Foods Alzheimer's disease Anthocyanins Antioxidants blackberry C-Reactive Protein (CRP) Cancer Cardiovascular Diseases CAROTENOIDS Catechin Ellagic Acid Flavonoids hyperglycemia hyperlipidemia hypertension Kaempferol Naringenin Parkinson's disease phytosterols POLYPHENOLS potassium QUERCETIN Strawberry Vitamin C VITAMIN E Sat, 18 Feb 2023 17:30:10 +0000 GMI Research Group 114933 at https://greenmedinfo.com A review of the impact of intermittent fasting on health and disease processes. https://greenmedinfo.com/article/review-impact-intermittent-fasting-health-and-disease-processes n/a PMID:  Ageing Res Rev. 2016 Oct 31. Epub 2016 Oct 31. PMID: 27810402 Abstract Title:  Impact of intermittent fasting on health and disease processes. Abstract:  Humans in modern societies typically consume food at least three times daily, while laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns often leads to metabolic morbidities (insulin resistance, excessive accumulation of visceral fat, etc.), particularly when associated with a sedentary lifestyle. Because animals, including humans, evolved in environments where food was relatively scarce, they developed numerous adaptations that enabled them to function at a high level, both physically and cognitively, when in a food-deprived/fasted state. Intermittent fasting (IF) encompasses eating patterns in which individuals go extended time periods (e.g., 16-48h) with little or no energy intake, with intervening periods of normal food intake, on a recurring basis. We use the term periodic fasting (PF) to refer to IF with periods of fasting or fasting mimicking diets lasting from 2 to as many as 21 or more days. In laboratory rats and mice IF and PF have profound beneficial effects on many different indices of health and, importantly, can counteract disease processes and improve functional outcome in experimental models of a wide range of age-related disorders including diabetes, cardiovascular disease, cancers and neurological disorders such as Alzheimer&#039;s disease Parkinson&#039;s disease and stroke. Studies of IF (e.g., 60% energy restriction on 2days per week or every other day), PF (e.g., a 5day diet providing 750-1100kcal) and time-restricted feeding (TRF; limiting the daily period of food intake to 8h or less) in normal and overweight human subjects have demonstrated efficacy for weight loss and improvements in multiple health indicators including insulin resistance and reductions in risk factors for cardiovascular disease. The cellular and molecular mechanisms by which IF improves health and counteracts disease processes involve activation of adaptive cellular stress response signaling pathways that enhance mitochondrial health, DNA repair and autophagy. PF also promotes stem cell-based regeneration as well as long-lasting metabolic effects. Randomized controlled clinical trials of IF versus PF and isoenergetic continuous energy restriction in human subjects will be required to establish the efficacy of IF in improving general health, and preventing and managing major diseases of aging. https://greenmedinfo.com/article/review-impact-intermittent-fasting-health-and-disease-processes#comments Alzheimer's Disease Cancers: All Cardiovascular Diseases Diabetes Mellitus: Type 2 Parkinson's Disease Stroke Fasting/Caloric Restriction Alzheimer's disease Cancers: All Cardiovascular Diseases Diabetes mellitus: Type 2 Intermittent Fasting Parkinson's disease stroke Review Wed, 30 Nov 2016 20:30:18 +0000 greenmedinfo 139657 at https://greenmedinfo.com AutismOne Joins With Focus Autism For AutismOne/Focus Autism 2015 Conference https://greenmedinfo.com/blog/autismone-joins-focus-autism-autismonefocus-autism-2015-conference <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2014<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="AutismOne Joins With Focus Autism For AutismOne/Focus Autism 2015 Conference" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/focusautism_autismone2.jpg" style="width: 400px; height: 299px;" /></p> <p class="rtecenter">Article Originally Published <strong><a href="http://www.prweb.com/releases/2014/11/prweb12346991.htm" rel="nofollow" target="_blank">Here</a></strong></p><p><a href="https://greenmedinfo.com/blog/autismone-joins-focus-autism-autismonefocus-autism-2015-conference" target="_blank">read more</a></p> https://greenmedinfo.com/blog/autismone-joins-focus-autism-autismonefocus-autism-2015-conference#comments Alzheimer's Disease Attention Deficit Disorder Attention Deficit Hyperactivity Disorder Autism Multiple Sclerosis Parkinson's Disease ADD ADHD Alzheimer's disease Autism AutismOne Brian Hooker CDC Focus Autism Multiple Sclerosis Parkinson's disease The Cutting-Edge Autism Conference Tue, 25 Nov 2014 19:42:31 +0000 GMI reporter 115301 at https://greenmedinfo.com Curcumin and piperine afforded a better neuroprotective effect compared to each of them alone. https://greenmedinfo.com/article/curcumin-and-piperine-afforded-better-neuroprotective-effect-compared-each-the n/a PMID:  Inflammopharmacology. 2016 Nov 16. Epub 2016 Nov 16. PMID: 27853890 Abstract Title:  Neuroprotective potential of curcumin in combination with piperine against 6-hydroxy dopamine induced motor deficit and neurochemical alterations in rats. Abstract:  AIM AND OBJECTIVE: 6-hydroxy dopamine (6-OHDA) is a neurotoxin which on intranigral administration produces severe nigrostriatal damage with motor and cognitive deficit in animals. Curcumin (CMN) in combination with bioenhancer piperine (PP) in 6-hydroxydopamine-induced Parkinsonian rats was used to investigate the antioxidant, neuromodulatory and neuroprotective mechanisms. MATERIALS AND METHODS: Hemi-Parkinson&#039;s rat model was developed with intranigral infusion of 6-OHDA (8 μg/2 μl, once, unilaterally), treatment with CMN (25 and 50 mg/kg) and combination of PP (2.5 mg/kg) with CMN (25 mg/kg) was given daily for 21 days starting from the 7th day after 6-OHDA infusion. The behavioral (locomotor, grip strength, and narrow beam walk) parameters were studied on weekly basis. On 22nd day, isolated brain preparations were subjected to biochemical (lipid peroxidation, glutathione, and nitrite), neuroinflammatory (IL-1β, IL-6, and TNF- α), and neurochemical (DA, NE, 5- HT, GABA, Glutamate, DOPAC, HVA, and 5-HIAA) analysis. RESULTS: Oral administration of CMN had significantly prevented behavioral, neuroinflammatory, and neurochemical changes and preserved the antioxidant potential of the nigrostriatum in rats treated with 6-OHDA. CONCLUSION: In the present study, PP and CMN had afforded a better neuroprotective effect compared to alone treatment on behavior, biochemical, neuroinflammatory, and neurochemical parameters in rats. https://greenmedinfo.com/article/curcumin-and-piperine-afforded-better-neuroprotective-effect-compared-each-the#comments Brain Inflammation Curcumin Parkinson's Disease Piperine Anti-Inflammatory Agents Interleukin-1 beta downregulation Interleukin-6 Downregulation Neuroprotective Agents Tumor Necrosis Factor (TNF) Alpha Inhibitor Anti-Inflammatory Agents Brain Inflammation CURCUMIN Interleukin-1 beta downregulation Natural Substance Synergy Parkinson's disease Piperine Animal Study Mon, 23 Jan 2017 23:11:26 +0000 greenmedinfo 142459 at https://greenmedinfo.com Curcumin Found to Outperform Pneumococcal Vaccines in Protecting Infants https://greenmedinfo.com/blog/curcumin-found-outperform-pneumococcal-vaccines-protecting-infants <p class="rtecenter"><img alt="Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/curcumin_%20Pneumococcal_vaccine_greenmedinfo.jpg" style="width: 600px; height: 400px;" title="Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants" /><br /> <strong style="font-size: 12px; letter-spacing: 0px;">Originally published on <a href="https://preventdisease.com/news/13/070313_Curcumin-Outperforms-Pneumococcal-Vaccines-In-Protecting-Infants.shtml" rel="nofollow" target="_blank" title="Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants">PreventDisease.com</a></strong></p><p><a href="https://greenmedinfo.com/blog/curcumin-found-outperform-pneumococcal-vaccines-protecting-infants" target="_blank">read more</a></p> https://greenmedinfo.com/blog/curcumin-found-outperform-pneumococcal-vaccines-protecting-infants#comments Alzheimer's Disease Arthritis Breast Cancer Cancers: All Curcumin Parkinson's Disease Pneumococcal Infections Turmeric anti-inflammatory Health Guide: Medicinal Spices Health Guide: Turmeric Health Guides: Healing Foods Vaccine Effects Weight Reduction Alzheimer's disease arthritis Cancer Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants influenza Parkinson's disease vaccination Weight Loss Tue, 28 Mar 2017 22:36:03 +0000 preventdisease.com 145526 at https://greenmedinfo.com Drum Circle Classes Improve Parkinson's Patients https://greenmedinfo.com/blog/drum-circle-classes-improve-parkinsons-patients <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2020<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Drum Circle Classes Improve Parkinson's Patients" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/old_man_drumming_parkinsons_greenmedinfo.gif" style="width: 600px; height: 575px;" title="Drum Circle Classes Improve Parkinson's Patients" /></p> <p><span style="font-size:18px;"><em><strong>Research published in the journal Movement Disorders Clinical Practice reveals that group drumming improves the condition of those with Parkinson's disease; a condition largely considered by conventional medical authorities to be irreversible and lethal</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/drum-circle-classes-improve-parkinsons-patients" target="_blank">read more</a></p> https://greenmedinfo.com/blog/drum-circle-classes-improve-parkinsons-patients#comments Parkinson's Disease Drumming Health Guide: Herbs and Traditional Knowledge drum circles drumming for brain health drumming for Parkinson's disease Parkinson's disease therapeutic actions Wed, 18 Jan 2017 22:13:09 +0000 Sayer Ji 142174 at https://greenmedinfo.com Extracts of Peganum harmala could prevent symptoms and reduced oxidative stress markers in rats with Parkinson’s disease. https://greenmedinfo.com/article/extracts-peganum-harmala-could-prevent-symptoms-and-reduced-oxidative-stress-m n/a PMID:  Iran J Pharm Res. 2016 ;15(1):275-81. PMID: 27610168 Abstract Title:  Peganum Harmala L. Extract Reduces Oxidative Stress and Improves Symptoms in 6-Hydroxydopamine-Induced Parkinson&#039;s Disease in Rats. Abstract:  Parkinson&#039;s disease is one of the most common neurodegenerative disorders. There are many documents about the effects of oxidative stress in Parkinson&#039;s disease etiology. Angiotensin II activates NADPH dependent oxidases and causes superoxides formation. Peganum harmala L. extract, which has angiotensin converting enzyme (ACE) inhibitory effect, is considered to evaluate oxidative stress inhibition and Parkinson&#039;s disease improvement. Male rats weighting 200-250 g were divided into 5 groups: Control, Neurotoxin (injection of 6-hydroxydopamine into left hemisphere substantia nigra), Peganum harmala&#039;s seeds aqueous extract (10 mg/kg) and captopril (5 mg/kg). Peganum harmala and captopril were injected intraperitonealy -144, -120, -96, -72, -48, -24, -2, 4 and 24 h relative to 6-hydroxydopamine injection time. Muscle stiffness, apomorphine induced unilateral rotation, amount of brain&#039;s protein oxidation and lipid peroxidation, ACE activity and histology of substantia nigra were assayed in all groups. Peganum harmala improved Muscle stiffness and one-direction rotation behavior significantly. It also reduced brain&#039;s lipid and protein oxidation levels in neurotoxin-injected rats significantly. In Peganum harmala group compared to control group, brain&#039;s ACE activity was significantly inhibited. In histological study, Peganum harmala prevented degeneration of dopaminergic neurons, too. In conclusion, aqueous extract of Peganum harmala could prevent symptoms and reduced oxidative stress markers in rats with Parkinson&#039;s disease induced by 6-hydroxydopamine. https://greenmedinfo.com/article/extracts-peganum-harmala-could-prevent-symptoms-and-reduced-oxidative-stress-m#comments Brain: Oxidative Stress Parkinson's Disease Syrian rue Antioxidants Neuroprotective Agents Antioxidants Brain: Oxidative Stress Neuroprotective Agents Parkinson's disease Plant Extracts Syrian rue Animal Study Fri, 01 Sep 2017 17:23:28 +0000 greenmedinfo 152555 at https://greenmedinfo.com Naringenin decreases α-synuclein expression and neuroinflammation in Parkinson's disease model. https://greenmedinfo.com/article/naringenin-decreases-synuclein-expression-and-neuroinflammation-parkinsons-dis n/a PMID:  Neurotox Res. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29427283 Abstract Title:  Naringenin Decreasesα-Synuclein Expression and Neuroinflammation in MPTP-Induced Parkinson&#039;s Disease Model in Mice. Abstract:  The present study was designed to ascertain the role of naringenin (NGN), a citrus fruit flavanone, against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-inducedα-synuclein (SYN) pathology and neuroinflammation in a mouse model. NGN was administered to C57BL/6J mice once a day for 5 consecutive days prior to the MPTP intoxication. On day 5, 40-50 min after the NGN or vehicle administration, MPTP was injected in two divided doses (2× 40 mg/kg, i.p. at 16 h apart). The animals were observed for motor functions 48 h after the first MPTP injection. The animals were then euthanized, the brains collected to analyze SYN pathology, cytokines, and oxidative stress levels in the substantia nigra region. The NGN significantly downregulated SYN and upregulated dopamine transporter (DAT) and tyrosine hydroxylase (TH) protein expressions. It also downregulated tumor necrosis factor-α (TNFα) and interleukin 1β (IL1β) mRNA expressions and improved superoxide dismutase levels. It also reduced glutathione levels when compared to vehicle-treated PD animals. The upregulation of TH corroborates to an increase in dopamine, DOPAC, and homovanillic acid turnover and motor functions with NGN treatment. To summarize, NGN, a dietary flavone, has the potential to counteract MPTP-induced dopaminergic degeneration by regulating SYN pathology, neuroinflammation, and oxidative stress. This warrants the investigation of NGN&#039;s potential effects in a genetic model of PD. https://greenmedinfo.com/article/naringenin-decreases-synuclein-expression-and-neuroinflammation-parkinsons-dis#comments Brain Inflammation Naringenin Parkinson's Disease Anti-Inflammatory Agents Antioxidants Interleukin-1 beta downregulation Neuroprotective Agents Tumor Necrosis Factor (TNF) Alpha Inhibitor Anti-Inflammatory Agents Antioxidants Brain Inflammation Naringenin Parkinson's disease Animal Study Sat, 10 Mar 2018 03:24:14 +0000 greenmedinfo 161005 at https://greenmedinfo.com Nobiletin and tangeretin may be beneficial in the treatment and prevention of Alzheimer`s and Parkinson's disease. https://greenmedinfo.com/article/nobiletin-and-tangeretin-may-be-beneficial-treatment-and-prevention-alzheimers n/a PMID:  CNS Neurol Disord Drug Targets. 2017 Mar 27. Epub 2017 Mar 27. PMID: 28474543 Abstract Title:  Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer&#039;s and Parkinson`s disease. Abstract:  Neurodegenerative diseases, namely Alzheimer`s disease and Parkinson&#039;s disease represent a deleterious impact worldwide. Despite extensive preclinical and clinical research in neurodegenerative disorders, therapeutic strategies aimed at the prevention and chronic treatment of neurodegenerative conditions have not been successfully translated to the clinic. Therefore, the identification of novel pharmacological intervention derived from natural products is warranted. Nobiletin and tangeretin are important citrus flavonoids derived from the peel and other parts of Citrus L. genus, and have been shown to exhibit neuroprotective effects in several in vitro and in vivo studies. Apart from there antioxidant and anti-inflammatory effects, nobiletin and tangeretin have been shown to attenuate cholinergic deficits, reduce the abnormal accumulation of neurotoxic amyloid-beta peptides, reverse N-methyl-D-aspartate (NMDA) receptor hypofunction, ameliorate ischemic injury, inhibit hyperphosphorylation of tau protein, enhance neprilysin levels, modulate several signaling cascades, and protect against 1-methyl-4-phenylpyridinium (MPP(+)) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity. Taken together, these naturally occurring phytochemicals may represent beneficial drug candidates for the treatment and prevention of Alzheimer`s and Parkinson&#039;s disease. https://greenmedinfo.com/article/nobiletin-and-tangeretin-may-be-beneficial-treatment-and-prevention-alzheimers#comments Alzheimer's Disease Nobiletin Parkinson's Disease Tangeretin Neuroprotective Agents Alzheimer's disease Neuroprotective Agents Nobiletin Parkinson's disease Tangeretin In Vitro Study Wed, 10 May 2017 00:54:15 +0000 greenmedinfo 147518 at https://greenmedinfo.com Palmitoylethanolamide prevents Parkinsonian phenotypes in aged mice. https://greenmedinfo.com/article/palmitoylethanolamide-prevents-parkinsonian-phenotypes-aged-mice n/a PMID:  Mol Neurobiol. 2018 Mar 19. Epub 2018 Mar 19. PMID: 29552727 Abstract Title:  N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice. Abstract:  Parkinson&#039;s disease (PD) is a neurodegenerative disease characterized by degeneration of dopaminergic neurons. Aging is a major risk factor for idiopathic PD. Several prior studies examined the neuroprotective effects of palmitoylethanolamide (PEA), alone or combined with antioxidants, in a model of PD induced by the dopaminergic toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Here, we analyzed the pretreatment effect of micronized PEA (PEAm) on neuroinflammation and neuronal cell death in the MPTP model. Male CD mice (21 months of age) were pre-treated for 60 days with PEAm. After this time, they received four intraperitoneal injections of MPTP over a 24-h period and were killed 7 days later. On the 8th day, brains were processed. Pretreatment with PEAm ameliorated behavioral deficits and the reductions in expression of tyrosine hydroxylase and dopamine transporter, while blunting the upregulation of α-synuclein and β3-tubulin in the substantia nigra after MPTP induction. Moreover, PEAm reduced proinflammatory cytokine expression and showed a pro-neurogenic effect in hippocampus. These findings propose this strategy as a valid approach to prevent neurodegenerative diseases associated with old age. https://greenmedinfo.com/article/palmitoylethanolamide-prevents-parkinsonian-phenotypes-aged-mice#comments Palmitoylethanolamide Parkinson's Disease Neuroprotective Agents Neuroprotective Agents Palmitoylethanolamide Parkinson's disease Animal Study Sat, 07 Apr 2018 13:18:46 +0000 greenmedinfo 162328 at https://greenmedinfo.com Pre-clinical evidence largely shows that CBD can produce beneficial effects in AD, PD and MS patients https://greenmedinfo.com/article/pre-clinical-evidence-largely-shows-cbd-can-produce-beneficial-effects-ad-pd-a n/a PMID:  CNS Neurol Disord Drug Targets. 2017 Apr 13. Epub 2017 Apr 13. PMID: 28412918 Abstract Title:  Neurological aspects of medical use of cannabidiol. Abstract:  BACKGROUND: Cannabidiol (CBD) is among the major secondary metabolites of Cannabis devoid of the delta-9-tetra-hydrocannabinol psychoactive effects. It is a resorcinol-based compound with a broad spectrum of potential therapeutic properties, including neuroprotective effects in numerous pathological conditions. CBD neuroprotection is due to its antioxidant and antiinflammatory activi-ties and the modulation of a large number of brain biological targets (receptors, channels) involved in the development and maintenance of neurodegenerative diseases. OBJECTIVE: Aim of the present review was to describe the state of art about the pre-clinical research, the potential use and, when existing, the clinical evidence related to CBD in the neurological field. METHOD: Collection of all the pre-clinical and clinical findings carried out investigating the effects of CBD alone, not in combination with other substances, in the neurological arena with the exclu-sion of studies on neuropsychiatric disorders. RESULTS: Laboratory and clinical studies on the potential role of CBD in Parkinson&#039;s disease (PD), Alzheimer&#039;s disease (AD), multiple sclerosis (MS), Huntington&#039;s disease (HD), amyotrophic lateral sclerosis ALS), cerebral ischemia, were examined. CONCLUSIONS: Pre-clinical evidence largely shows that CBD can produce beneficial effects in AD, PD and MS patients, but its employment for these disorders needs further confirmation from well designed clinical studies. CBD pre-clinical demonstration of antiepileptic activity is supported by recent clinical studies in human epileptic subjects resistant to standard antiepileptic drugs showing its potential use in children and young adults affected by refractory epilepsy. Evidence for use of CBD in PD is still not supported by sufficient data whereas only a few studies including a small number of patients are available. https://greenmedinfo.com/article/pre-clinical-evidence-largely-shows-cbd-can-produce-beneficial-effects-ad-pd-a#comments Alzheimer's Disease Cannabidiol Multiple Sclerosis Parkinson's Disease Neuroprotective Agents Alzheimer's disease Cannabidiol Multiple Sclerosis Neuroprotective Agents Parkinson's disease Review Mon, 24 Apr 2017 15:27:31 +0000 greenmedinfo 146686 at https://greenmedinfo.com The critical review results indicate that compounds in avocado are unique antioxidants, and thus may be promising as effective neuropreventive agents. https://greenmedinfo.com/article/critical-review-results-indicate-compounds-avocado-are-unique-antioxidants-and n/a PMID:  Adv Neurobiol. 2016 ;12:337-54. PMID: 27651262 Abstract Title:  Avocado as a Major Dietary Source of Antioxidants and Its Preventive Role in Neurodegenerative Diseases. Abstract:  Avocados have a high content of phytochemicals especially antioxidants with potential neuroprotective effect. Aging is the major risk factor for neurodegenerative diseases such as Alzheimer&#039;s and Parkinson&#039;s diseases. A large body of evidence indicates that oxidative stress is involved in the pathophysiology of these diseases. Oxidative stress can induce neuronal damages and modulate intracellular signaling, ultimately leading to neuronal death by apoptosis or necrosis. There is evidence for increased oxidative damage to macromolecules in amyotrophic lateral sclerosis, Huntington&#039;s disease, Parkinson&#039;s disease, and Alzheimer&#039;s disease. Thus, antioxidants have been used for their effectiveness in reducing these deleterious effects and neuronal death in many in vitro and in vivo studies. The critical review results indicate that compounds in avocado are unique antioxidants, preferentially suppressing radical generation, and thus may be promising as effective neuropreventive agents. The diverse array of bioactive nutrients present in avocado plays a pivotal role in the prevention and cure of various neurodegenerative diseases. https://greenmedinfo.com/article/critical-review-results-indicate-compounds-avocado-are-unique-antioxidants-and#comments Alzheimer's Disease Amyotrophic lateral sclerosis (ALS) Avocado Huntington Disease Neurodegenerative Diseases Parkinson's Disease Antioxidants Neuroprotective Agents Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Avocado Huntington Disease Neurodegenerative diseases Parkinson's disease Review Tue, 07 Feb 2017 17:08:36 +0000 greenmedinfo 143100 at https://greenmedinfo.com The findings suggest that B. caapi alone has a mild antiparkinsonian effect. https://greenmedinfo.com/article/findings-suggest-b-caapi-alone-has-mild-antiparkinsonian-effect n/a PMID:  Phytother Res. 2018 Jan 24. Epub 2018 Jan 24. PMID: 29368409 Abstract Title:  The effect of Banisteriopsis caapi (B. caapi) on the motor deficits in the MPTP-treated common marmoset model of Parkinson&#039;s disease. Abstract:  Banisteriopsis caapi (B. caapi) contains harmine, harmaline, and tetrahydroharmine, has monoamine oxidase inhibitory activity, and has reported antiparkinsonian activity in humans when imbibed as a tea; however, its effects are poorly documented. For this reason, motor function was assessed in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets following administration of B. caapi extract (28.4-113.6 mg/kg; po), harmine (0.1 and 0.3 mg/kg; sc), and selegiline (10 mg/kg; sc), alone or with a submaximal dose of L-3,4-dihydroxyphenylalanine (L-DOPA; 4-7 mg/kg). L-DOPA reversed motor disability, increased locomotor activity, and induced moderate dyskinesia. B. caapi did not increase locomotor activity or induce dyskinesia but at 56.8 and 113.6 mg/kg improved motor disability. The L-DOPA response was unaltered by co-administration of B. caapi. Harmine (0.1 and 0.3 mg/kg) produced a mild improvement in motor disability without affecting locomotor activity or dyskinesia but had no effect on the L-DOPA-induced antiparkinsonian response. Selegiline (10 mg/kg) alone improved motor function to the same extent as L-DOPA, but with only mild dyskinesia, and did not alter the response to L-DOPA, although dyskinesia was reduced. The findings suggest that B. caapi alone has a mild antiparkinsonian effect but does not enhance the L-DOPA response or reduce dyskinesia. https://greenmedinfo.com/article/findings-suggest-b-caapi-alone-has-mild-antiparkinsonian-effect#comments Ayahuasca Parkinson's Disease Ayahuasca Parkinson's disease Animal Study Sat, 27 Jan 2018 03:05:18 +0000 greenmedinfo 158903 at https://greenmedinfo.com This highlights recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders via the gut-brain axis. https://greenmedinfo.com/article/highlights-recent-advances-understanding-probiotic-modulation-neurological-and n/a PMID:  J Microbiol. 2018 Mar ;56(3):172-182. Epub 2018 Feb 28. PMID: 29492874 Abstract Title:  Mind-altering with the gut: Modulation of the gut-brain axis with probiotics. Abstract:  It is increasingly evident that bidirectional interactions exist among the gastrointestinal tract, the enteric nervous system, and the central nervous system. Recent preclinical and clinical trials have shown that gut microbiota plays an important role in these gut-brain interactions. Furthermore, alterations in gut microbiota composition may be associated with pathogenesis of various neurological disorders, including stress, autism, depression, Parkinson&#039;s disease, and Alzheimer&#039;s disease. Therefore, the concepts of the microbiota-gut-brain axis is emerging. Here, we review the role of gut microbiota in bidirectional interactions between the gut and the brain, including neural, immune-mediated, and metabolic mechanisms. We highlight recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders via the gut-brain axis. https://greenmedinfo.com/article/highlights-recent-advances-understanding-probiotic-modulation-neurological-and#comments Alzheimer's Disease Autism Depression Parkinson's Disease Probiotics Neuroprotective Agents Alzheimer's disease Autism Depression Gut-brain Axis Parkinson's disease probiotics Review Fri, 02 Mar 2018 09:45:46 +0000 greenmedinfo 160633 at https://greenmedinfo.com Vaccines' Dark Inferno: What Is Not on Insert Labels? https://greenmedinfo.com/blog/vaccines-dark-inferno-what-not-insert-labels <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2015<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Vaccines' Dark Inferno: What Is Not on Insert Labels?" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/flu-vaccine.jpg" style="width: 600px; height: 450px;" /></p> <p class="rtecenter">Originally published on <strong><a href="http://www.townsendletter.com/Dec2009/vaccines1209.html" rel="nofollow" target="_blank">Townsendletter.com</a></strong></p><p><a href="https://greenmedinfo.com/blog/vaccines-dark-inferno-what-not-insert-labels" target="_blank">read more</a></p> https://greenmedinfo.com/blog/vaccines-dark-inferno-what-not-insert-labels#comments ADD ADHD Alzheimer's Disease Asthma Autism Chronic Fatigue Syndrome Crohn's Disease H1N1 Leaky Gut Syndrome Parkinson's Disease Vaccination: All Vaccination: Influenza Vaccination: Mumps-Measles-Rubella (MMR) ADD ADHD Alzheimer's disease Asthma Autism Chronic Fatigue Syndrome Crohn's Disease FDA H1N1 Influenza Vaccine Janine Roberts Leaky gut syndrome MMR Vaccine Parkinson's disease Vaccines World Health Organization Tue, 27 Jan 2015 19:44:03 +0000 rgale 116139 at https://greenmedinfo.com