hyperinsulinism https://greenmedinfo.com/category/keywords/hyperinsulinism en Is Genetically Modified Baker’s Yeast Spreading Obesity and Diabetes? https://greenmedinfo.com/blog/genetically-modified-baker-s-yeast-spreading-obesity-and-diabetes <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2014<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Is Genetically Modified Baker's Yeast Spreading Obesity and Diabetes?" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/image001.jpg" style="width: 300px; height: 225px;" /></p> <p class="rtecenter">Originally published on&nbsp;<strong><a href="http://fearlessparent.org/gm-bakers-yeast-obesity-diabetes/" rel="nofollow" target="_blank">Fearless Parent</a></strong>, like us on&nbsp;<strong><a href="http://www.facebook.com/FearlessParentMedia" rel="nofollow" target="_blank">Facebook</a></strong></p> <p>The current contentious <strong><a href="/anti-therapeutic-action/genetically-modified-organisms">GMO</a></strong> debate focuses on the health impacts of foods that have been genetically engineered&nbsp;on purpose&nbsp;for taste/texture, resistance to pests/disease, and other qualities.</p><p><a href="https://greenmedinfo.com/blog/genetically-modified-baker-s-yeast-spreading-obesity-and-diabetes" target="_blank">read more</a></p> https://greenmedinfo.com/blog/genetically-modified-baker-s-yeast-spreading-obesity-and-diabetes#comments Arthritis Hypertension Hypoglycemia Obesity Type 2 Diabetes Genetically Modified Organisms GMO Research Center GMOs Baker&#039;s Yeast carpel tunnel syndrome GMO high blood pressure hyperinsulinism Hypoglycemia obesity Saccharomyces Cerevisiae Thu, 07 Aug 2014 17:35:03 +0000 sydneyrsinger 114299 at https://greenmedinfo.com Lactobacilluscasei Zhang administration exert both preventive and ameliorative effect on oral glucose tolerance. https://greenmedinfo.com/article/lactobacilluscasei-zhang-administration-exert-both-preventive-and-ameliorative n/a PMID:  Eur J Nutr. 2014 Feb ;53(1):221-32. PMID: 23797890 Abstract Title:  Probiotic Lactobacillus casei Zhang ameliorates high-fructose-induced impaired glucose tolerance in hyperinsulinemia rats. Abstract:  AIM: To evaluate the preventive and therapeutic effects of Lactobacilluscasei Zhang on impaired glucose tolerance (IGT) by using fructose-induced hyperinsulinemia rats. METHODS: Rats were fed 25 % fructose solution for hyperinsulinemia with L.casei Zhang for prevention or therapy. Serum levels of insulin, glucagon-like peptide-2 (GLP-2), osteocalcin, malondialdehyde (MDA), total intestinal bile acids and hepatic glycogen contents were determined by assay kits. The major bacteria from feces and liver expression of adiponectin receptor 2 (AdipoR2), liver X receptor-α (LXR-α), peroxisome proliferator-activated receptor gamma (PPAR-γ) and vitamin K epoxide reductase complex subunit 1 mRNA were assessed by RT-PCR. Pancreas injury was evaluated by histological analysis. RESULTS: Lactobacilluscasei Zhang significantly increased numbers of Lactobacillus and Bifidobacterium and decreased Clostridium in the intestine (p&lt;0.01). Meanwhile, liver glycogen contents were significantly decreased (p&lt;0.05). In preventive group, accompanied by significantly lower insulin and GLP-2 levels (p&lt;0.05), L.casei Zhang prevented rats from an increase in oral glucose tolerance area under curve (AUC) which was significant in hyperinsulinemia group (p&lt;0.05). In therapeutic group, L.casei Zhang administration possessed improved glucose tolerance (p&lt;0.05), which were associated with increased osteocalcin level (p&lt;0.01), improved intestinal bile acids secretion (p = 0.060), decreased serum MDA levels (p&lt;0.05) and upregulation of LXR-α, PPAR-γ and AdipoR2 gene expression, as well as an increase in Bacteroides fragilis (p&lt;0.05). CONCLUSIONS: Lactobacilluscasei Zhang administration exert both preventive and ameliorative effect on oral glucose tolerance AUC in IGT rats but may be via different mechanisms. L.casei Zhang could prevent rats from increased AUC through GLP-2 lowering, while the ameliorative effect in high-fructose-fed post-adolescent rats may be via B. fragilis enriched vitamin K2-dependent osteocalcin mechanism in which AdipoR2, LXR-α and PPAR-γ signaling were involved. https://greenmedinfo.com/article/lactobacilluscasei-zhang-administration-exert-both-preventive-and-ameliorative#comments Hyperinsulinism Lactobacillus casei Fructose Malondialdehyde Down-regulation hyperinsulinism Lactobacillus casei Malondialdehyde Down-regulation Animal Study Thu, 08 Jun 2017 03:12:57 +0000 greenmedinfo 148847 at https://greenmedinfo.com