Depression: Stress Related https://greenmedinfo.com/taxonomy/term/76398/all en Electro-acupuncture regulates glucose metabolism in chronic stress model rats. https://greenmedinfo.com/article/electro-acupuncture-regulates-glucose-metabolism-chronic-stress-model-rats PMID:  Sci Rep. 2020 Jul 9 ;10(1):11281. Epub 2020 Jul 9. PMID: 32647204 Abstract Title:  Electro-acupuncture regulates glucose metabolism in chronic stress model rats. Abstract:  Studies have shown that acupuncture is very effective in treating chronic stress depression. However, little is known about the therapeutic mechanism of electro-acupuncture. Metabolomics, on the other hand, is a technology that determines the metabolic changes of organisms caused by various interventions as a whole and is related to the overall effect of electro-acupuncture (EA).HNMR, serum sample analysis, and histopathology and molecular biology analysis were used to evaluate the effects of EA. The results show that electro-acupuncture points can regulate the heat pain threshold of chronic stress model rats and change the morphology of adrenal cortex cells Structure, and regulate the contents of corticotropin-releasing hormone, Corticosterone (CORT), glucose, alanine and valine in the samples. These findings help to clarify the therapeutic mechanism of electro-acupuncture on heterologous chronic stress model rats. The effect of electro-acupuncture on improving chronic stress is likely to be achieved by regulating glucose metabolism, which can provide a reference for clinical acupuncture treatment of chronic stress depression. <p><a href="https://greenmedinfo.com/article/electro-acupuncture-regulates-glucose-metabolism-chronic-stress-model-rats" target="_blank">read more</a></p> https://greenmedinfo.com/article/electro-acupuncture-regulates-glucose-metabolism-chronic-stress-model-rats#comments Depression: Stress Related Antidepressive Agents Electroacupuncture Animal Study Wed, 22 Jul 2020 11:29:17 +0000 greenmedinfo 223968 at https://greenmedinfo.com Melatonin may stimulate dopaminergic synthesis in the hippocampus in order to suppress stress-induced behaviour. https://greenmedinfo.com/article/melatonin-may-stimulate-dopaminergic-synthesis-hippocampus-order-suppress-stre PMID:  Folia Biol (Praha). 2016 ;62(6):250-257. PMID: 28189148 Abstract Title:  Anxiety and Hyperlocomotion Induced by Chronic Unpredictable Mild Stress Can Be Moderated with Melatonin Treatment. Abstract:  Preclinical studies have shown that melatonin exercised antidepressant-like and anxiolyticlike effects in animal models of anxiety. The aim of the present study was to correlate the changes in behaviour induced by melatonin treatment with the activity of the dopaminergic system in the hippocampus of Wistar rats exposed to chronic, unpredictable, mild stress (CUMS). Male Wistar rats, 11 weeks old, were subjected to chronic stress for 28 successive days. Separate groups of control and stressed rats were intraperitoneally injected daily either with melatonin (10 mg/kg/day, i.p.) or placebo (5% ethanol). The open-field and elevated plus-maze tests were used to assess locomotor activities and anxiety levels. The content of dopamine (DA) in the hippocampal tissues was determined using radioenzymatic assay, while changes in tyrosine hydroxylase (TH) mRNA and protein levels in the hippocampus were determined using real-time RT-PCR and Western immunoblotting. Chronic stress led to reduction in the hippocampal dopaminergic content without affecting the levels of TH protein. These changes were accompanied by increased locomotor activity and higher anxiety levels in the open-field test. Administration of melatonin for 28 days resulted in an increase in the hippocampal DA content as a result of elevated TH protein levels. Melatonin showed an improvement in anxiety-like behaviour along with significantly reduced exploration. We could conclude that melatonin may stimulate dopaminergic synthesis in the hippocampus in order to suppress stress-induced behaviour. <p><a href="https://greenmedinfo.com/article/melatonin-may-stimulate-dopaminergic-synthesis-hippocampus-order-suppress-stre" target="_blank">read more</a></p> https://greenmedinfo.com/article/melatonin-may-stimulate-dopaminergic-synthesis-hippocampus-order-suppress-stre#comments Anxiety Depression: Stress Related Melatonin Stress Anti-Anxiety Agents Animal Study Thu, 16 Feb 2017 22:51:01 +0000 greenmedinfo 143674 at https://greenmedinfo.com Mountain bikers reported copious benefits to mental health and well-being related to their engagement. https://greenmedinfo.com/article/mountain-bikers-reported-copious-benefits-mental-health-and-well-being-related PMID:  Front Psychol. 2018 ;9:1642. Epub 2018 Sep 19. PMID: 30283372 Abstract Title:  Why Do You Ride?: A Characterization of Mountain Bikers, Their Engagement Methods, and Perceived Links to Mental Health and Well-Being. Abstract:  Mountain biking is an increasingly popular outdoor activity on the extreme sport continuum. Extreme and high-risk sports have been investigated using a variety of motivational theories with sensation seeking a dominant theme; however, behavioral and motivational homogeneity within these types of populations should not be assumed. Recent studies have highlighted the therapeutic potential of extreme sports and similar outdoor activities. The aim of this study was to describe the characteristics of mountain biking participants, their engagement methods, and perceived benefits to mental health and well-being. This was a cross-sectional survey and participants were recruited via social media. An online questionnaire specific to the domain of mountain biking was developed. Analysis of the full sample (= 1,484) and of three independent paired sub-samples was conducted using SPSS. The sub-samples compared the results of males and females; younger and older riders; and those who have recently engaged in downhill mountain biking and those who have not. The results have succeeded in identifying some disparities in mountain biker characteristics and engagement methods. The results suggest that some riders found pleasure in higher risk engagement. The study proposes various explanations for the disproportion of women in mountain biking. Irrespective of the confounding factors related to rider characteristics or engagement methods, mountain bikers reported copious benefits to mental health and well-being related to their engagement. There was a high reported usage of mountain biking as a coping strategy. As such, this study provides insights that could inform the development of outdoor activities as interventions for mental health. <p><a href="https://greenmedinfo.com/article/mountain-bikers-reported-copious-benefits-mental-health-and-well-being-related" target="_blank">read more</a></p> https://greenmedinfo.com/article/mountain-bikers-reported-copious-benefits-mental-health-and-well-being-related#comments Anxiety Depression Depression: Stress Related Mood Disorders Anti-Anxiety Agents Antidepressive Agents Exercise: Cycling Exercise: Green Human Study Thu, 10 Oct 2019 03:20:59 +0000 greenmedinfo 198595 at https://greenmedinfo.com Musk exhibits an antidepressant effect an animal model of depression. https://greenmedinfo.com/article/musk-exhibits-antidepressant-effect-animal-model-depression PMID:  Cell Tissue Res. 2016 Aug 1. Epub 2016 Aug 1. PMID: 27481508 Abstract Title:  The antidepressant effect of musk in an animal model of depression: a histopathological study. Abstract:  Depression is a significant public health concern all over the world, especially in modern communities. This study aims to assess the efficacy of musk in alleviating the behavioral, biochemical and histopathological changes induced by chronic unpredictable mild stress (CUMS) in an animal model of depression and to explore the underlying mechanism of this effect. Male Swiss albino mice were divided into four groups (n = 10): control, CUMS, CUMS+fluoxetine and CUMS+musk. At the end of the experiment, behavioral tests were administered and serum corticosterone and testosterone levels were assessed. Surface markers, proteins and gene expressions of brain-derived neurotropic factor (BDNF) and glucocorticoid receptors (GRs) in the hippocampus were assessed. The immunoexpression of glial fibrillary acidic protein, Ki67 and caspase-3 was also assessed. Data were analyzed using the Statistical Package for the Social Sciences and a P value of less than 0.05 was considered significant. Musk alleviated the behavioral changes caused by CUMS and reduced elevated corticosterone levels. It reduced CUMS-induced neuronal atrophy in the CA3 and dentate gyrus of the hippocampus and restored astrocytes. Musk reduced the neuro- and glial apoptosis observed in stressed mice in a manner comparable to that of fluoxetine. Musk induced these effects through up-regulating both BDNF and GR gene and protein expressions. Musk has an antidepressant-like effect in an animal model of depression, so it is advisable to assess its efficacy in people continually exposed to stressors. https://greenmedinfo.com/article/musk-exhibits-antidepressant-effect-animal-model-depression#comments Depression: Stress Related Musk (Animal) Antidepressive Agents Animal Study Thu, 11 Aug 2016 21:23:37 +0000 greenmedinfo 132344 at https://greenmedinfo.com The antidepressant-like effect of chrysin in chronically stressed mice was similar to fluoxetine. https://greenmedinfo.com/article/antidepressant-effect-chrysin-chronically-stressed-mice-was-similar-fluoxetine PMID:  Eur J Pharmacol. 2016 Sep 5. Epub 2016 Sep 5. PMID: 27609609 Abstract Title:  Neurochemical factors associated with the antidepressant-like effect of flavonoid chrysin in chronically stressed mice. Abstract:  Chrysin is a flavonoid which is found in bee propolis, honey and various plants. Antidepressant-like effect of chrysin in chronically stressed mice was previously demonstrated by our group. Conversely, neurochemical factors associated with this effect require further investigations. Thus, we investigated the possible involvement of pro-inflammatory cytokines, kynurenine pathway (KP), 5-hydroxytryptamine (5-HT) metabolism and caspases activities in the effect of chrysin in mice exposed to unpredictable chronic stress (UCS). UCS applied for 28 days induced a depressive-like behavior, characterized by decrease in the time of grooming in the splash test and by increase in the immobility time in the tail suspension test. Oral treatment with chrysin (5 or 20mg/kg, 28 days), similarly to fluoxetine (10mg/kg, positive control), culminated in the prevention of these alterations. UCS elevated plasma levels of corticotropin-releasing hormone and adrenocorticotropic hormone, as well the tumor necrosis factor-α, interleukin-1β, interleukin-6 and kynurenine levels in the prefrontal cortex (PFC) and hippocampus (HP). UCS induced the decrease in the 5-HT levels in the HP and the increase in the indoleamine-2,3-dioxygenase, caspase 3 and 9 activities in the PFC and HP. Treatment with chrysin, similarly tofluoxetine, promoted the attenuation of these alterations occasioned by UCS. These results corroborated with the antidepressant potential of chrysin in the treatment of psychiatric diseases. Furthermore, this work indicated the association of pro-inflammatory cytokines synthesis, KP, 5-HT metabolismand caspases activities with the action exercised by chrysin in mice exposed to UCS. https://greenmedinfo.com/article/antidepressant-effect-chrysin-chronically-stressed-mice-was-similar-fluoxetine#comments Chrysin Depression: Stress Related Antidepressive Agents Fluoxetine (trade name Prozac) Natural Substances Versus Drugs Animal Study Mon, 12 Sep 2016 13:22:05 +0000 greenmedinfo 134887 at https://greenmedinfo.com The Health Benefits of Whole-Body Vibration (WBV): A Scientific Review https://greenmedinfo.com/blog/health-benefits-whole-body-vibration-wbv-scientific-review <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2024<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/jarret@greenmedinfo.com/images/Untitled%20design-5(14).png" style="width: 600px; height: 600px;" /></p> <p><span style="font-size:18px;"><em><strong>Imagine a health and fitness solution that began in the cosmos, aiding astronauts, and has now landed right in our living rooms. Whole-Body Vibration (WBV) isn't just a modern wellness trend; it's a scientifically-backed approach that's shaking up the way we think about our health. Let's dive into the vibrations that promise more than just a buzz!</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/health-benefits-whole-body-vibration-wbv-scientific-review" target="_blank">read more</a></p> https://greenmedinfo.com/blog/health-benefits-whole-body-vibration-wbv-scientific-review#comments Back Pain Cardiovascular Disease Depression: Stress Related Obesity Osteoarthritis Respiratory Arthritic Arthritis Athletic Performance Health Guide: Aging Health Guide: Alzheimer's Health Guide: Chiropractic Care Health Guide: Obesity and Dieting Inflammatory Osteoporosis/Osteopenia arthritis Cardiovascular Disease Chronic Pain Neurological Conditions obesity Osteoporosis Tue, 23 Jan 2024 04:00:00 +0000 Sayer Ji 286862 at https://greenmedinfo.com