Aphasia https://greenmedinfo.com/taxonomy/term/774/all en A case study of a woman who used yogic breathing as ayurvedic medicine in her recovery from poststroke aphasia. https://greenmedinfo.com/article/case-study-woman-who-used-yogic-breathing-ayurvedic-medicine-her-recovery-post PMID:  Top Stroke Rehabil. 2014 May-Jun;21(3):272-9. PMID: 24985394 Abstract Title:  Yogic breathing and Ayurveda in aphasia: a case study. Abstract:  PURPOSE: We present a case study of a woman who used yogic breathing as Ayurvedic medicine in her recovery from poststroke aphasia. Ayurvedic medicine is one of the most ancient medicines of the world, but it is not widely used for aphasia rehabilitation in many Western countries. The description of this case aims to further the understanding of the benefits that this type of medicine may provide to poststroke patients living with aphasia. METHOD: After her stroke, the patient received brief conventional language therapy for her aphasia. At 5 weeks post stroke, she received no further conventional rehabilitation; instead, she consulted with a Vedic priest. She followed a regimen of different body manipulations, yogic breathing techniques, and ingestion of coconut oil. Cognitive and language testing was performed throughout a 3-month period while she was involved in this therapy. RESULTS: Overall, improvement was noted in language, visual attention, and some mood measures. CONCLUSION: Although case studies lead to limited conclusions, changes were observed for this individual using Ayurvedic medicine. Given the changes in language and some aspects of cognition seen in this patient, further exploration of the effectiveness of yogic breathing and Ayurvedic medicine in the treatment of poststroke aphasia is warranted. https://greenmedinfo.com/article/case-study-woman-who-used-yogic-breathing-ayurvedic-medicine-her-recovery-post#comments Aphasia Stroke Stroke: Attenuation/Recovery Ayurvedic Medicine Yoga Human: Case Report Fri, 22 May 2015 00:08:32 +0000 greenmedinfo 117646 at https://greenmedinfo.com A combination of MIT and rTMS applied to the right Broca's homolog has the potential to improve speech and language outcomes for at least some people. https://greenmedinfo.com/article/combination-mit-and-rtms-applied-right-brocas-homolog-has-potential-improve-sp PMID:  Front Psychol. 2014 ;5:37. Epub 2014 Feb 4. PMID: 24550864 Abstract Title:  Augmenting melodic intonation therapy with non-invasive brain stimulation to treat impaired left-hemisphere function: two case studies. Abstract:  The purpose of this study was to investigate whether or not the right hemisphere can be engaged using Melodic Intonation Therapy (MIT) and excitatory repetitive transcranial magnetic stimulation (rTMS) to improve language function in people with aphasia. The two participants in this study (GOE and AMC) have chronic non-fluent aphasia. A functional Magnetic Resonance Imaging (fMRI) task was used to localize the right Broca&#039;s homolog area in the inferior frontal gyrus for rTMS coil placement. The treatment protocol included an rTMS phase, which consisted of 3 treatment sessions that used an excitatory stimulation method known as intermittent theta burst stimulation, and a sham-rTMS phase, which consisted of 3 treatment sessions that used a sham coil. Each treatment session was followed by 40 min of MIT. A linguistic battery was administered after each session. Our findings show that one participant, GOE, improved in verbal fluency and the repetition of phrases when treated with MIT in combination with TMS. However, AMC showed no evidence of behavioral benefit from this brief treatment trial. Post-treatment neural activity changes were observed for both participants in the left Broca&#039;s area and right Broca&#039;s homolog. These case studies indicate that a combination of MIT and rTMS applied to the right Broca&#039;s homolog has the potential to improve speech and language outcomes for at least some people with post-stroke aphasia. https://greenmedinfo.com/article/combination-mit-and-rtms-applied-right-brocas-homolog-has-potential-improve-sp#comments Aphasia Magnet Therapy Melodic Intonation Therapy Human: Case Report Wed, 13 Jan 2016 21:11:35 +0000 greenmedinfo 123117 at https://greenmedinfo.com Acupuncture is effective in improving functional communication in post-stroke aphasia. https://greenmedinfo.com/article/acupuncture-effective-improving-functional-communication-post-stroke-aphasia PMID:  Wien Klin Wochenschr. 2019 Apr 18. Epub 2019 Apr 18. PMID: 31001680 Abstract Title:  Acupuncture is effective in improving functional communication in post-stroke aphasia : A systematic review and meta-analysis of randomized controlled trials. Abstract:  OBJECTIVE: In this meta-analysis the authors evaluated the effectiveness of acupuncture in improving functional communication and language function in post-stroke aphasia (PSA) patients.METHODS: Data sources: MEDLINE, EMBASE, CENTRAL, AMED, SinoMed, CNKI, VIP, and Wanfang databases, ICTRP, ISRCTN, EUCTR, ClinicalTrials.gov, and Stroke Trials Registries. A search was carried out for randomized controlled trials (RCTs) investigating the effects of acupuncture compared with no treatment or placebo acupuncture on post-stroke aphasia (PSA). The searched records were independently screened by two authors, who extracted the data, and assessed risk of biasof the included RCTs. Data aggregation and risk of bias evaluation were conducted on Review Manager Version 5.3. The protocol was registered in the PROSPERO database (CRD42016037543).RESULTS: A total of 28 RCTs involving 1747 patients (883 patients in the treatment group and 864 patients in the control group) were included in the quantitative synthesis. The results demonstrated significant effects of acupuncture in improving PSA functional communication (P <p><a href="https://greenmedinfo.com/article/acupuncture-effective-improving-functional-communication-post-stroke-aphasia" target="_blank">read more</a></p> https://greenmedinfo.com/article/acupuncture-effective-improving-functional-communication-post-stroke-aphasia#comments Aphasia Stroke: Attenuation/Recovery Acupuncture Meta Analysis Review Wed, 24 Apr 2019 17:49:14 +0000 greenmedinfo 185971 at https://greenmedinfo.com After MIT there was a significant improvement in verbal communication and earlier treatment may lead to even greater improvements. https://greenmedinfo.com/article/after-mit-there-was-significant-improvement-verbal-communication-and-earlier-t PMID:  Neurorehabil Neural Repair. 2014 Jan 20 ;28(6):536-544. Epub 2014 Jan 20. PMID: 24449708 Abstract Title:  The Efficacy and Timing of Melodic Intonation Therapy in Subacute Aphasia. Abstract:  Background. Little is known about the efficacy of language production treatment in subacute severe nonfluent aphasia. Although Melodic Intonation Therapy (MIT) is a language production treatment for this disorder, until now MIT effect studies have focused on chronic aphasia. Purpose. This study examines whether language production treatment with MIT is effective in subacute severe nonfluent aphasia. Methods. A multicenter, randomized controlled trial was conducted in a waiting-list control design: patients were randomly allocated to the experimental group (MIT) or the control group (control intervention followed by delayed MIT). In both groups, therapy started at 2 to 3 months poststroke and was given intensively (5 h/wk) during 6 weeks. In a second therapy period, the control group received 6 weeks of intensive MIT. The experimental group resumed their regular treatment. Assessment was done at baseline (T1), after the first intervention period (T2), and after the second intervention period (T3). Efficacy was evaluated at T2. The impact of delaying MIT on therapy outcome was also examined. Results. A total of 27 participants were included: n = 16 in the experimental group and n = 11 in the control group. A significant effect in favor of MIT on language repetition was observed for trained items, with mixed results for untrained items. After MIT there was a significant improvement in verbal communication but not after the control intervention. Finally, delaying MIT was related to less improvement in the repetition of trained material. Conclusions. In these patients with subacute severe nonfluent aphasia, language production treatment with MIT was effective. Earlier treatment may lead to greater improvement. https://greenmedinfo.com/article/after-mit-there-was-significant-improvement-verbal-communication-and-earlier-t#comments Aphasia Melodic Intonation Therapy Significant Treatment Outcome Human Study Wed, 13 Jan 2016 22:02:23 +0000 greenmedinfo 123119 at https://greenmedinfo.com Although MIT is regarded as a language treatment for Broca’s aphasia, it could also act on motor speech deficits in this aphasic syndrome. https://greenmedinfo.com/article/although-mit-regarded-language-treatment-broca-s-aphasia-it-could-also-act-mot PMID:  Front Neurol. 2014 ;5:7. Epub 2014 Jan 28. PMID: 24478754 Abstract Title:  Melodic intonation therapy: back to basics for future research. Abstract:  We present a critical review of the literature on melodic intonation therapy (MIT), one of the most formalized treatments used by speech-language therapist in Broca&#039;s aphasia. We suggest basic clarifications to enhance the scientific support of this promising treatment. First, therapeutic protocols using singing as a speech facilitation technique are not necessarily MIT. The goal of MIT is to restore propositional speech. The rationale is that patients can learn a new way to speak through singing by using language-capable regions of the right cerebral hemisphere. Eventually, patients are supposed to use this way of speaking permanently but not to sing overtly. We argue that many treatment programs covered in systematic reviews on MIT&#039;s efficacy do not match MIT&#039;s therapeutic goal and rationale. Critically, we identified two main variations of MIT: the French thérapie mélodique et rythmée (TMR) that trains patients to use singing overtly as a facilitation technique in case of speech struggle and palliative versions of MIT that help patients with the most severe expressive deficits produce a limited set of useful, readymade phrases. Second, we distinguish between the immediate effect of singing on speech production and the long-term effect of the entire program on language recovery. Many results in the MIT literature can be explained by this temporal perspective. Finally, we propose that MIT can be viewed as a treatment of apraxia of speech more than aphasia. This issue should be explored in future experimental studies. https://greenmedinfo.com/article/although-mit-regarded-language-treatment-broca-s-aphasia-it-could-also-act-mot#comments Aphasia Brain Damage Melodic Intonation Therapy Review Wed, 13 Jan 2016 21:18:56 +0000 greenmedinfo 123118 at https://greenmedinfo.com Aphasia: Acquired https://greenmedinfo.com/disease/aphasia-acquired <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="300" alt="" src="//cdn.greenmedinfo.com/sites/default/files/Aphasia_1.jpg?1468446603" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_benjaminec&#039;&gt;benjaminec / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Aphasia Tue, 14 Apr 2009 07:14:04 +0000 greenmedinfo 19020 at https://greenmedinfo.com Both the NMT and SLT therapies are effective treatments in the chronic stage of stroke and NMT is effective in subacute post-stroke aphasic patients. https://greenmedinfo.com/article/both-nmt-and-slt-therapies-are-effective-treatments-chronic-stage-stroke-and-n PMID:  Ann Rehabil Med. 2013 Aug ;37(4):556-62. Epub 2013 Aug 26. PMID: 24020037 Abstract Title:  The therapeutic effect of neurologic music therapy and speech language therapy in post-stroke aphasic patients. Abstract:  OBJECTIVE: To investigate the therapeutic effect of neurologic music therapy (NMT) and speech language therapy (SLT) through improvement of the aphasia quotient (AQ) in post-stroke aphasic patients.METHODS: Twenty-one post-stroke, nonfluent aphasia patients who had ischemic/hemorrhagic stroke on radiologic evaluation were divided into the NMT and SLT groups. They received NMT and SLT for 1 month. Language function was assessed by Korean version-Western Aphasia Battery before and after therapy. NMT consisted of therapeutic singing and melodic intonation therapy, and SLT consisted of language-oriented therapy.RESULTS: Significant improvements were revealed in AQ, repetition, and naming after therapy in the NMT group and improvements in repetition in the SLT group of chronic stroke patients (p https://greenmedinfo.com/article/both-nmt-and-slt-therapies-are-effective-treatments-chronic-stage-stroke-and-n#comments Aphasia Stroke: Attenuation/Recovery Melodic Intonation Therapy Significant Treatment Outcome Human Study Wed, 13 Jan 2016 22:10:13 +0000 greenmedinfo 123120 at https://greenmedinfo.com Combining anodal-tDCS with MIT may further recovery from post-stroke aphasia. https://greenmedinfo.com/article/combining-anodal-tdcs-mit-may-further-recovery-post-stroke-aphasia PMID:  Front Psychol. 2011 ;2:230. Epub 2011 Sep 26. PMID: 21980313 Abstract Title:  Non-invasive brain stimulation enhances the effects of melodic intonation therapy. Abstract:  Research has suggested that a fronto-temporal network in the right hemisphere may be responsible for mediating melodic intonation therapy&#039;s (MIT) positive effects on speech recovery. We investigated the potential for a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), to augment the benefits of MIT in patients with non-fluent aphasia by modulating neural activity in the brain during treatment with MIT. The polarity of the current applied to the scalp determines the effects of tDCS on the underlying tissue: anodal-tDCS increases excitability, whereas cathodal tDCS decreases excitability. We applied anodal-tDCS to the posterior inferior frontal gyrus of the right hemisphere, an area that has been shown both to contribute to singing through the mapping of sounds to articulatory actions and to serve as a key region in the process of recovery from aphasia, particularly in patients with large left hemisphere lesions. The stimulation was applied while patients were treated with MIT by a trained therapist. Six patients with moderate to severe non-fluent aphasia underwent three consecutive days of anodal-tDCS + MIT, and an equivalent series of sham-tDCS + MIT. The two treatment series were separated by 1 week, and the order in which the treatments were administered was randomized. Compared to the effects of sham-tDCS + MIT, anodal-tDCS + MIT led to significant improvements in fluency of speech. These results support the hypothesis that, as the brain seeks to reorganize and compensate for damage to left hemisphere language centers, combining anodal-tDCS with MIT may further recovery from post-stroke aphasia by enhancing activity in a right hemisphere sensorimotor network for articulation. https://greenmedinfo.com/article/combining-anodal-tdcs-mit-may-further-recovery-post-stroke-aphasia#comments Aphasia Melodic Intonation Therapy Significant Treatment Outcome Human Study Wed, 13 Jan 2016 22:46:33 +0000 greenmedinfo 123123 at https://greenmedinfo.com Dysphasia https://greenmedinfo.com/disease/dysphasia <div class="field field-image"> <div class="field-items"> <div class="field-item odd"> <img class="imagefield imagefield-field_image" width="450" height="300" alt="" src="//cdn.greenmedinfo.com/sites/default/files/Aphasia_6.jpg?1474408582" /> </div> </div> </div> <div class="field field-copyright"> <div class="field-items"> <div class="field-item odd"> Copyright: &lt;a href=&#039;http://www.123rf.com/profile_benjaminec&#039;&gt;benjaminec / 123RF Stock Photo&lt;/a&gt; </div> </div> </div> <fieldset class="fieldgroup group-facebook-like-info"><legend>Facebook Like Info</legend><div class="field field-facebook-total-count"> <div class="field-items"> <div class="field-item odd"> 0 </div> </div> </div> </fieldset> Aphasia Tue, 14 Apr 2009 07:17:01 +0000 greenmedinfo 19775 at https://greenmedinfo.com Electroacupuncture and scalp acupuncture combined with language training is remarkable in treating aphasia after severe craniocerebral injury. https://greenmedinfo.com/article/electroacupuncture-and-scalp-acupuncture-combined-language-training-remarkable PMID:  Am J Transl Res. 2022 ;14(8):5923-5930. Epub 2022 Aug 15. PMID: 36105057 Abstract Title:  Effect of electroacupuncture and scalp acupuncture combined with language rehabilitation training on cognitive and speech functions of aphasia patients after craniocerebral injury. Abstract:  OBJECTIVES: To explore the clinical effect of electroacupuncture and scalp acupuncture combined with language rehabilitation training on cognitive and speech functions of patients with aphasia after craniocerebral injury.METHODS: Seventy patients with aphasia after craniocerebral injury from January 2020 and January 2021 were retrospectively collected after filtering. Among them, 35 patients received language rehabilitation training and were included into a control group, and 35 patients who received electroacupuncture and scalp acupuncture combined with language rehabilitation training were included in a study group. Aphasia quotient score, Loewenstein occupational therapy cognitive assessment (LOTCA) score and Boston Diagnostic Aphasia Examination (BDAE) score of the two groups were compared. The relative risk factors of cognitive function and speech function in the patients were explored by multiple regression analysis.RESULTS: The pretreatment aphasia quotient and LOTCA score between the two groups showed no obvious distinction (P&gt;0.05). After treatment, the LOTCA and BDAE scores in the study group were obviously better than those in the control group (P<p><a href="https://greenmedinfo.com/article/electroacupuncture-and-scalp-acupuncture-combined-language-training-remarkable" target="_blank">read more</a></p> https://greenmedinfo.com/article/electroacupuncture-and-scalp-acupuncture-combined-language-training-remarkable#comments Aphasia Acupuncture Neuroprotective Agents Human Study Sun, 27 Nov 2022 20:47:31 +0000 greenmedinfo 267101 at https://greenmedinfo.com Emerging research has shown that long-term music training and the associated sensorimotor skill learning can be a strong stimulus for neuroplastic changes. https://greenmedinfo.com/article/emerging-research-has-shown-long-term-music-training-and-associated-sensorimot PMID:  Prog Brain Res. 2015 ;217:37-55. Epub 2015 Feb 11. PMID: 25725909 Abstract Title:  Musicians and music making as a model for the study of brain plasticity. Abstract:  Playing a musical instrument is an intense, multisensory, and motor experience that usually commences at an early age and requires the acquisition and maintenance of a range of sensory and motor skills over the course of a musician&#039;s lifetime. Thus, musicians offer an excellent human model for studying behavioral-cognitive as well as brain effects of acquiring, practicing, and maintaining these specialized skills. Research has shown that repeatedly practicing the association of motor actions with specific sound and visual patterns (musical notation), while receiving continuous multisensory feedback will strengthen connections between auditory and motor regions (e.g., arcuate fasciculus) as well as multimodal integration regions. Plasticity in this network may explain some of the sensorimotor and cognitive enhancements that have been associated with music training. Furthermore, the plasticity of this system as a result of long term and intense interventions suggest the potential for music making activities (e.g., forms of singing) as an intervention for neurological and developmental disorders to learn and relearn associations between auditory and motor functions such as vocal motor functions. https://greenmedinfo.com/article/emerging-research-has-shown-long-term-music-training-and-associated-sensorimot#comments Aphasia Childhood Cognitive Disorders Melodic Intonation Therapy Music Review Wed, 13 Jan 2016 19:31:29 +0000 greenmedinfo 123112 at https://greenmedinfo.com In this study mental singing showed a positive effect on parkinsonian gait. https://greenmedinfo.com/article/study-mental-singing-showed-positive-effect-parkinsonian-gait PMID:  Brain Nerve. 2011 Dec ;63(12):1370-7. PMID: 22147456 Abstract Title:  [Music therapy for dementia and higher cognitive dysfunction: a review]. Abstract:  Music is known to affect the human mind and body. Music therapy utilizes the effects of music for medical purposes. The history of music therapy is quite long, but only limited evidence supports its usefulness in the treatment of higher cognitive dysfunction. As for dementia, some studies conclude that music therapy is effective for preventing cognitive deterioration and the occurrence of behavioral and psychological symptoms of dementia (BPSD). In patients receiving music therapy for the treatment of higher cognitive dysfunction, aphasia was reported as the most common symptom. Many studies have been conducted to determine whether singing can improve aphasic symptoms: singing familiar and/or unfamiliar songs did not show any positive effect on aphasia. Melodic intonation therapy (MIT) is a method that utilizes melody and rhythm to improve speech output. MIT is a method that is known to have positive effects on aphasic patients. Some studies of music therapy for patients with unilateral spatial neglect; apraxia; hemiparesis; and walking disturbances, including parkinsonian gait, are available in the literature. Studies showed that the symptoms of unilateral spatial neglect and hemiparesis significantly improved when musical instruments were played for several months as a part of the music therapy. Here, I describe my study in which mental singing showed a positive effect on parkinsonian gait. Music is interesting, and every patient can go through training without any pain. Future studies need to be conducted to establish evidence of the positive effects of music therapy on neurological and neuropsychological symptoms. https://greenmedinfo.com/article/study-mental-singing-showed-positive-effect-parkinsonian-gait#comments Aphasia Apraxias Dementia Parkinson's Disease Stroke: Attenuation/Recovery Melodic Intonation Therapy Music Review Wed, 13 Jan 2016 22:37:38 +0000 greenmedinfo 123122 at https://greenmedinfo.com Intense long-term Melodic Intonation Therapy leads to remodeling of the right arcuate fasciculus. https://greenmedinfo.com/article/intense-long-term-melodic-intonation-therapy-leads-remodeling-right-arcuate-fa PMID:  Ann N Y Acad Sci. 2009 Jul ;1169:385-94. PMID: 19673813 Abstract Title:  Evidence for plasticity in white-matter tracts of patients with chronic Broca&#039;s aphasia undergoing intense intonation-based speech therapy. Abstract:  Recovery from aphasia can be achieved through recruitment of either perilesional brain regions in the affected hemisphere or homologous language regions in the nonlesional hemisphere. For patients with large left-hemisphere lesions, recovery through the right hemisphere may be the only possible path. The right-hemisphere regions most likely to play a role in this recovery process are the superior temporal lobe (important for auditory feedback control), premotor regions/posterior inferior frontal gyrus (important for planning and sequencing of motor actions and for auditory-motor mapping), and the primary motor cortex (important for execution of vocal motor actions). These regions are connected reciprocally via a major fiber tract called the arcuate fasciculus (AF), however, this tract is not as well developed in the right hemisphere as it is in the dominant left. We tested whether an intonation-based speech therapy (i.e., melodic intonation therapy [MIT]), which is typically administered in an intense fashion with 75-80 daily therapy sessions, would lead to changes in white-matter tracts, particularly the AF. Using diffusion tensor imaging (DTI), we found a significant increase in the number of AF fibers and AF volume comparing post- with pretreatment assessments in six patients that could not be attributed to scan-to-scan variability. This suggests that intense, long-term MIT leads to remodeling of the right AF and may provide an explanation for the sustained therapy effects that were seen in these six patients. https://greenmedinfo.com/article/intense-long-term-melodic-intonation-therapy-leads-remodeling-right-arcuate-fa#comments Aphasia Melodic Intonation Therapy Significant Treatment Outcome Human Study Wed, 13 Jan 2016 23:22:17 +0000 greenmedinfo 123126 at https://greenmedinfo.com M.I.T. results in rehabilitation of aphasia in Italian patients. https://greenmedinfo.com/article/mit-results-rehabilitation-aphasia-italian-patients PMID:  Front Hum Neurosci. 2015 ;9:520. Epub 2015 Sep 24. PMID: 26441615 Abstract Title:  Rehabilitation of aphasia: application of melodic-rhythmic therapy to Italian language. Abstract:  Aphasia is a complex disorder, frequent after stroke (with an incidence of 38%), with a detailed pathophysiological characterization. Effective approaches are crucial for devising an efficient rehabilitative strategy, in order to address the everyday life and professional disability. Several rehabilitative procedures are based on psycholinguistic, cognitive, psychosocial or pragmatic approaches, including amongst those with a neurobehavioral approach the Melodic Intonation Therapy (MIT). Van Eeckhout&#039;s adaptation of MIT to French language (Melodic-Rhythmic Therapy: MRT) has implemented the training strategy by adding a rhythmic structure reproducing French prosody. The purpose of this study was to adapt MRT rehabilitation procedures to Italian language and to verify its efficacy in a group of six chronic patients (five males) with severe non-fluent aphasia and without specific aphasic treatments during the previous 9 months. The patients were treated 4 days a week for 16 weeks, with sessions of 30-40 min. They were assessed 6 months after the end of the treatment (follow-up). The patients showed a significant improvement at the Aachener Aphasie Test (AAT) in different fields of spontaneous speech, with superimposable results at the follow-up. Albeit preliminary, these findings support the use of MRT in the rehabilitation after stroke. Specifically, MRT seems to benefit from its stronger structure than the available stimulation-facilitation procedures and allows a better quantification of the rehabilitation efficacy. https://greenmedinfo.com/article/mit-results-rehabilitation-aphasia-italian-patients#comments Aphasia Melodic Intonation Therapy Human Study Wed, 13 Jan 2016 14:34:00 +0000 greenmedinfo 123108 at https://greenmedinfo.com Melodic intonation therapy acts through promotion of left hemisphere activation. https://greenmedinfo.com/article/melodic-intonation-therapy-acts-through-promotion-left-hemisphere-activation PMID:  J Clin Exp Neuropsychol. 2010 Mar ;32(3):309-14. Epub 2009 Aug 5. PMID: 19657914 Abstract Title:  Changes in maps of language activity activation following melodic intonation therapy using magnetoencephalography: two case studies. Abstract:  Two patients with chronic expressive aphasia underwent two blocks of melodic intonation therapy (MIT) each. Maps of language-specific neurophysiological activity were obtained prior to and after each MIT block during a covert action naming task using magnetoencephalography. Both patients exhibited increased left hemisphere activation after MIT. The patient who responded positively to therapy exhibited decreasing activation within areas of the right hemisphere homotopic to left hemisphere language areas compared to baseline after both blocks of MIT. In contrast, the patient who did not show improvement after therapy exhibited increasing activation in these areas of the right hemisphere after therapy. Results are consistent with hypotheses that melodic intonation therapy acts through promotion of left hemisphere activation. https://greenmedinfo.com/article/melodic-intonation-therapy-acts-through-promotion-left-hemisphere-activation#comments Aphasia Melodic Intonation Therapy Human Study Wed, 13 Jan 2016 23:26:45 +0000 greenmedinfo 123127 at https://greenmedinfo.com