Aflatoxin

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7 Diseases Researched for Aflatoxin

Name	AC	CK
Liver Cancer	6	35
Aflatoxicosis	3	22
Hepatitis B	2	12
Liver Damage: Aflatoxin-Induced	2	12
Breastfeeding Concerns: Chemical Exposure	1	10
Liver Cancer: Prevention	1	10
Tumors	1	1

3 Adverse Pharmacological Actions Researched for Aflatoxin

Name	AC	CK
Carcinogenic	5	33
Hepatotoxic	1	10
Tumorigenic	1	1

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

View the Evidence:
24 Abstracts with Aflatoxin Research

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[+]

Aflatoxin B1 exposure increases the risk for primary liver cancer in north Indian population.Oct 01, 2011

Click here to read the entire abstract

Pubmed Data : Clin Biochem. 2011 Oct ;44(14-15):1235-40. Epub 2011 Aug 10. PMID: 21854762

Article Published Date : Oct 01, 2011

Study Type : Human Study

Additional Links

Diseases : Liver Cancer, Liver Cancer: Prevention

Problem Substances : Aflatoxin

Adverse Pharmacological Actions : Carcinogenic

[+]

Aflatoxin contamination of commercial maize products during an outbreak of acute aflatoxicosis in eastern and central Kenya.Nov 30, 2005

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 2005 Dec ;113(12):1763-7. PMID: 16330360

Article Published Date : Nov 30, 2005

Study Type : Human Study

Additional Links

Diseases : Aflatoxicosis

Problem Substances : Aflatoxin, Mycotoxin

[+]

Aflatoxin exposure contributes to the development of primary liver cancer in patients with chronic hepatitis.Jun 22, 2010

Click here to read the entire abstract

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2010 Jun 22 ;90(24):1665-9. PMID: 20979873

Article Published Date : Jun 22, 2010

Study Type : Human Study

Additional Links

Diseases : Hepatitis B , Liver Cancer

Additional Keywords : Diseases that are Linked

Problem Substances : Aflatoxin

Adverse Pharmacological Actions : Carcinogenic, Hepatotoxic

[+]

Aflatoxin is capable of transferring to newborns through breast milk. Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2010 Jan;48(1):314-9. Epub 2009 Oct 20. PMID: 19850097

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Diseases : Aflatoxicosis, Breastfeeding Concerns: Chemical Exposure

Problem Substances : Aflatoxin

[+]

Oral doses of calcium montmorillonite clay reduced urinary biomarkers and bioavailability of Fumonisin B1 and aflatoxin, two contaminants of grain that are carcinogenic.Jan 06, 2012

Click here to read the entire abstract

Pubmed Data : Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012 Jan 6. Epub 2012 Jan 6. PMID: 22324939

Article Published Date : Jan 06, 2012

Study Type : Animal Study, Human Study

Additional Links

Substances : Montmorillonite

Diseases : Aflatoxicosis, Esophageal Cancer

Additional Keywords : Calcium Bentonite Clay, Montmorillonite Clay

Anti Therapeutic Actions : Proinflammatory

Problem Substances : Aflatoxin, Fumonisin

[+]

There is evidence that aflatoxin exposure plays a role in the pathogenesis of liver cancer in the US population. Jan 01, 1999

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 1999 ;35(1):27-33. PMID: 10624703

Article Published Date : Jan 01, 1999

Study Type : Human Study

Additional Links

Diseases : Aflatoxicosis, Liver Cancer, Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Tumor Suppressor Protein p53 Upregulation

Problem Substances : Aflatoxin

Adverse Pharmacological Actions : Carcinogenic

[+]

A phenolics rich extract of ginger had protective effects against Aflatoxin B1-induced oxidative stress and hepatotoxicity.May 01, 2017

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2017 May 2 ;91:415-424. Epub 2017 May 2. PMID: 28475920

Article Published Date : May 01, 2017

Study Type : Animal Study

Additional Links

Substances : Ginger, Gingerol

Diseases : Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Hepatoprotective, Nrf2 activation

Problem Substances : Aflatoxin

[+]

Aflatoxin is capable of generating liver cancer in combination with hepatitis B infection. Dec 01, 2011

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2011 Dec 1 ;311(1):1-10. Epub 2011 Jun 24. PMID: 21821357

Article Published Date : Dec 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Hepatitis B , Liver Cancer

Additional Keywords : Problem Substance Synergy

Problem Substances : Aflatoxin

Adverse Pharmacological Actions : Carcinogenic

[+]

Both Nigella sativa and date reduce the toxic effects of aflatoxin-B1 in liver and kidney.Jun 30, 2008

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Health Sci (Qassim). 2008 Jul ;2(2):26-44. PMID: 21475486

Article Published Date : Jun 30, 2008

Study Type : Animal Study

Additional Links

Substances : Dates, Nigella sativa (aka Black Seed)

Diseases : Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

Problem Substances : Aflatoxin

[+]

Exposure assessment of mycotoxins in cow's milk in Argentina.Jan 31, 2012

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2012 Feb ;50(2):250-7. Epub 2011 Oct 10. PMID: 22015550

Article Published Date : Jan 31, 2012

Study Type : Animal Study

Additional Links

Problem Substances : Aflatoxin, Deoxynivalenol (DON), Mycotoxin, Zearalenone (ZEA)

[+]

Influence of herbicide glyphosate on growth and aflatoxin B1 production by Aspergillus section Flavi strains isolated from soil on in vitro assay.Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : J Environ Sci Health B. 2013 ;48(12):1070-9. PMID: 24007484

Article Published Date : Dec 31, 2012

Study Type : Environmental

Additional Links

Diseases : Aflatoxicosis

Problem Substances : Aflatoxin, Glyphosate, Glyphosate formulations

[+]

L. plantarum C88 may alleviate aflatoxin B1 toxicity by increasing fecal AFB1 excretion.Oct 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arq Bras Oftalmol. 2016 Nov-Dec;79(6):357-362. PMID: 28076559

Article Published Date : Oct 31, 2016

Study Type : Animal Study

Additional Links

Substances : Lactobacillus plantarum

Diseases : Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Antioxidants

Problem Substances : Aflatoxin

[+]

Lactobacillus plantarum BS22 promotes gut microbial homeostasis in broiler chickens exposed to aflatoxin B1.Aug 02, 2017

Click here to read the entire abstract

Pubmed Data : J Anim Physiol Anim Nutr (Berl). 2017 Aug 3. Epub 2017 Aug 3. PMID: 28771826

Article Published Date : Aug 02, 2017

Study Type : Animal Study

Additional Links

Substances : Lactobacillus plantarum

Diseases : Aflatoxicosis

Pharmacological Actions : Gastrointestinal Agents, Gastroprotective

Problem Substances : Aflatoxin

[+]

Saffron tea intake prevents learning and memory defects and neurobiochemical alterations induced by aflatoxin B1 exposure.May 01, 2017

Click here to read the entire abstract

Pubmed Data : Neurochem Res. 2017 May 2. Epub 2017 May 2. PMID: 28462452

Article Published Date : May 01, 2017

Study Type : Animal Study

Additional Links

Substances : Saffron

Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents

Problem Substances : Aflatoxin

[+]

Sulforaphane may attenuate aflatoxin-induced liver carcinogenesis. May 01, 2011

Click here to read the entire abstract

Pubmed Data : Toxicol Sci. 2011 May ;121(1):57-62. Epub 2011 Jan 28. PMID: 21278056

Article Published Date : May 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Aflatoxicosis, Liver Cancer, Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Problem Substances : Aflatoxin

[+]

The administration of pumpkin seed oil diminished aflatoxin-induced adverse effectsNov 30, 2013

Click here to read the entire abstract

Pubmed Data : Environ Toxicol. 2013 Dec ;28(12):681-8. Epub 2011 Aug 31. PMID: 24591108

Article Published Date : Nov 30, 2013

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seeds

Diseases : Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Problem Substances : Aflatoxin

[+]

These results suggest that sea buckthorn oil intake decrease the severity of aflatoxin B1 toxic effects in the liver.Mar 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Poult Sci. 2013 Apr ;92(4):966-74. PMID: 23472020

Article Published Date : Mar 31, 2013

Study Type : Animal Study

Additional Links

Substances : Sea buckthorn

Diseases : Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Hepatoprotective

Additional Keywords : Plant Oils

Problem Substances : Aflatoxin

[+]

Aflatoxin exposure contributes to the pathogenesis of liver cancer, and may be attenuated through chlorophyllin. Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 Jan 1:1-9. Epub 2011 Jan 1. PMID: 21623489

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Substances : Chlorophyllin

Diseases : Liver Cancer

Pharmacological Actions : Chemopreventive

Problem Substances : Aflatoxin

Adverse Pharmacological Actions : Carcinogenic

[+]

An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Mar 31, 2014

Click here to read the entire abstract

Pubmed Data : Crit Rev Toxicol. 2014 Apr ;44(4):348-91. Epub 2014 Feb 4. PMID: 24494825

Article Published Date : Mar 31, 2014

Study Type : Review

Additional Links

Diseases : DNA damage

Additional Keywords : Drug: Tamoxifen

Problem Substances : Aflatoxin, Tamoxifen, Vinyl chloride

Adverse Pharmacological Actions : Carcinogenic, Genotoxic, Mutagenic

[+]

Global food regulation: MycotoxinsAug 31, 2007

Click here to read the entire abstract

Pubmed Data : Anal Bioanal Chem. 2007 Sep ;389(1):147-57. Epub 2007 May 17. PMID: 17508207

Article Published Date : Aug 31, 2007

Study Type : Review

Additional Links

Diseases : Mycotoxin Toxicity

Problem Substances : Aflatoxin, Deoxynivalenol (DON), Fumonisin, Mycotoxin, Zearalenone (ZEA)

[+]

Phloretin has a strong chemopreventive effect against aflatoxin B1.Dec 31, 2011

Click here to read the entire abstract

Pubmed Data : Biofactors. 2012 Jan-Feb;38(1):34-43. Epub 2012 Jan 18. PMID: 22253071

Article Published Date : Dec 31, 2011

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Chemopreventive, Nrf2 activation

Additional Keywords : Chemopreventive, Dose Response, Liver Damage: Aflatoxin-Induced, Nrf2 activation, Phloretin

Problem Substances : Aflatoxin

[+]

Piperine inhibits Aflatoxin B1 production in Aspergillus flavus by modulating fungal oxidative stress response.Aug 18, 2017

Click here to read the entire abstract

Pubmed Data : Fungal Genet Biol. 2017 Aug 19. Epub 2017 Aug 19. PMID: 28830793

Article Published Date : Aug 18, 2017

Study Type : In Vitro Study

Additional Links

Substances : Piperine

Diseases : Aspergillosis

Pharmacological Actions : Antioxidants

Problem Substances : Aflatoxin

[+]

Review: Toxicology of mycotoxins.Dec 31, 2009

Click here to read the entire abstract

Pubmed Data : EXS. 2010 ;100:31-63. PMID: 20358681

Article Published Date : Dec 31, 2009

Study Type : Review

Additional Links

Diseases : Cancers: All, Mycotoxicity

Problem Substances : Aflatoxin, Deoxynivalenol (DON), Mycotoxin, Ochratoxin A , Zearalenone (ZEA)

[+]

There are a number of natural and synthetic chemicals with tumor-inducing effects.Oct 01, 2005

Click here to read the entire abstract

Pubmed Data : Discov Med. 2005 Oct;5(29):472-7. PMID: 20704845

Article Published Date : Oct 01, 2005

Study Type : Commentary

Additional Links

Diseases : Tumors

Problem Substances : Aflatoxin, Aromatic hydrocarbons, Cadmium, Dioxins, Estrogen Receptor Agonists, Lead, N-Nitrosamines, Nickelous acetate, Nickelous Sulfate, Polycyclic aromatic hydrocarbon, Tamoxifen, Vinyl chloride

Adverse Pharmacological Actions : Tumorigenic

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One quarter of our global food supply contains a hidden hormone-disrupting danger that can cause serious acute, as well as chronic adverse health effects. A recent study on young girls in New Jersey found detectable concentrations in the urine of 2/3rds of the population sampled.

Aflatoxins: Poisons Hiding in Plain Sight

Written by Dr. B.J. Hardick, D.C.

There’s a good chance these toxins are lurking in your child’s lunchbox—and they are some of the most poisonous natural compounds known to humankind. Find out how to eliminate them from your home and from your body.

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Focus Your Research

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View the Evidence: 24 Abstracts with Aflatoxin Research

Limited to Members Only

Currently Available Sorting Options

Aflatoxin B1 exposure increases the risk for primary liver cancer in north Indian population.Oct 01, 2011

Aflatoxin contamination of commercial maize products during an outbreak of acute aflatoxicosis in eastern and central Kenya.Nov 30, 2005

Aflatoxin exposure contributes to the development of primary liver cancer in patients with chronic hepatitis.Jun 22, 2010

Aflatoxin is capable of transferring to newborns through breast milk. Jan 01, 2010

Oral doses of calcium montmorillonite clay reduced urinary biomarkers and bioavailability of Fumonisin B1 and aflatoxin, two contaminants of grain that are carcinogenic.Jan 06, 2012

There is evidence that aflatoxin exposure plays a role in the pathogenesis of liver cancer in the US population. Jan 01, 1999

A phenolics rich extract of ginger had protective effects against Aflatoxin B1-induced oxidative stress and hepatotoxicity.May 01, 2017

Aflatoxin is capable of generating liver cancer in combination with hepatitis B infection. Dec 01, 2011

Both Nigella sativa and date reduce the toxic effects of aflatoxin-B1 in liver and kidney.Jun 30, 2008

Exposure assessment of mycotoxins in cow's milk in Argentina.Jan 31, 2012

Influence of herbicide glyphosate on growth and aflatoxin B1 production by Aspergillus section Flavi strains isolated from soil on in vitro assay.Dec 31, 2012

L. plantarum C88 may alleviate aflatoxin B1 toxicity by increasing fecal AFB1 excretion.Oct 31, 2016

Lactobacillus plantarum BS22 promotes gut microbial homeostasis in broiler chickens exposed to aflatoxin B1.Aug 02, 2017

Saffron tea intake prevents learning and memory defects and neurobiochemical alterations induced by aflatoxin B1 exposure.May 01, 2017

Sulforaphane may attenuate aflatoxin-induced liver carcinogenesis. May 01, 2011

The administration of pumpkin seed oil diminished aflatoxin-induced adverse effectsNov 30, 2013

These results suggest that sea buckthorn oil intake decrease the severity of aflatoxin B1 toxic effects in the liver.Mar 31, 2013

Aflatoxin exposure contributes to the pathogenesis of liver cancer, and may be attenuated through chlorophyllin. Jan 01, 2011

An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Mar 31, 2014

Global food regulation: MycotoxinsAug 31, 2007

Phloretin has a strong chemopreventive effect against aflatoxin B1.Dec 31, 2011

Piperine inhibits Aflatoxin B1 production in Aspergillus flavus by modulating fungal oxidative stress response.Aug 18, 2017

Review: Toxicology of mycotoxins.Dec 31, 2009

There are a number of natural and synthetic chemicals with tumor-inducing effects.Oct 01, 2005

Aflatoxin Related Articles

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Aflatoxin

View the Evidence:
24 Abstracts with Aflatoxin Research