Alendronate (trade name Fosamax)

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View the Evidence: Problem Substances

Pubmed Data : Arch Intern Med. 2001 Jan 8;161(1):107-10. PMID: 11146706
Study Type : Human Study

Pubmed Data : Mod Pathol. 1999 Dec;12(12):1152-7. PMID: 10619269
Study Type : Human Study

Pubmed Data : Aliment Pharmacol Ther. 2000 Nov;14(11):1451-7. PMID: 11069316
Study Type : Human Study

Pubmed Data : Injury. 2008 Feb;39(2):224-31. Epub 2008 Jan 28. PMID: 18222447
Study Type : Human Study
Additional Links

Pubmed Data : Arch Intern Med. 2008 Apr 28;168(8):826-31. PMID: 18443257
Study Type : Human Study

Pubmed Data : J Orthop Trauma. 2008 May-Jun;22(5):346-50. PMID: 18448990
Study Type : Human Study

Pubmed Data : Pharmacoepidemiol Drug Saf. 2000 Sep;9(5):371-6. PMID: 19025842
Study Type : Human Study

Pubmed Data : Int J Cardiol. 2010 Jan 3. Epub 2010 Jan 3. PMID: 20051297
Study Type : Human Study

Pubmed Data : Thyroid. 2009 May;19(5):437-42. PMID: 19415993
Study Type : Human Study

Pubmed Data : Am J Gastroenterol. 1997 Aug;92(8):1322-5. PMID: 9260798
Study Type : Human Study

Pubmed Data : J Oral Maxillofac Surg. 2005 Nov;63(11):1567-75. PMID: 16243172
Study Type : Human Study

Pubmed Data : Acta Gastroenterol Latinoam. 2001 May;31(2):59-63. PMID: 11471319
Study Type : Human Study

Pubmed Data : J Bone Joint Surg Am. 2009 Nov;91(11):2556-61. PMID: 19884427
Study Type : Human Study
Additional Links

Pubmed Data : Endoscopy. 2005 Aug;37(8):740-4. PMID: 16032493
Study Type : Human Study

Pubmed Data : Hong Kong Med J. 2007 Dec;13(6):485-9. PMID: 18057440
Study Type : Human Study

Pubmed Data : Dig Dis Sci. 2007 Aug;52(8):1879-89. Epub 2007 Apr 5. PMID: 17410434
Study Type : Animal Study

Pubmed Data : J Physiol Pharmacol. 2009 Sep;60(3):85-93. PMID: 19826186
Study Type : Animal Study

Pubmed Data : Inflammopharmacology. 2007 Oct;15(5):196-202. PMID: 17943251
Study Type : Animal Study
Additional Links
Adverse Pharmacological Actions : Ulcerogenic : CK(66) : AC(9)

Pubmed Data : Joint Bone Spine. 2007 Jan;74(1):39-47. Epub 2006 Nov 28. PMID: 17196423
Study Type : Animal Study

Pubmed Data : Prescrire Int. 2000 Jun;9(47):70-2. PMID: 11010741
Study Type : Review

Pubmed Data : Arq Gastroenterol. 2001 Apr-Jun;38(2):129-31. PMID: 11793943
Study Type : Commentary

Pubmed Data : Hormones (Athens). 2009 Apr-Jun;8(2):96-110. PMID: 19570737
Study Type : Review

Pubmed Data : Calcif Tissue Int. 2008 Mar;82(3):191-201. Epub 2008 Feb 8. PMID: 18259679
Study Type : In Vitro Study

Pubmed Data : Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jul;106(1):5-13. Epub 2008 May 27. PMID: 18504149
Study Type : In Vitro Study

Pubmed Data : Arch Biochem Biophys. 2000 Jan 1;373(1):231-41. PMID: 10620343
Study Type : In Vitro Study



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Written by Sayer Ji, Founder
The present-day definitions of Osteoporosis and Osteopenia were arbitrarily conceived by the WHO in the early 90's and then projected upon millions of women's bodies seemingly in order to convince them they had a drug-treatable, though symptomless, disease.
It saddens me to see older women diagnosed with “osteopenia” or “osteoporosis” listening to their doctors and taking supplemental calcium and even problematic drugs called bisphosphonates. These are irrational, dogmatic, harmful approaches to the problem of degrading bone as we age.

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