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View the Evidence:
46 Abstracts with Aspartame Research

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Pubmed Data : Prev Med. 2008 Jul;47(1):136-9. Epub 2008 Apr 8. PMID: 18495230
Study Type : Human Study
Additional Links
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Pubmed Data : Nature. 2014 Sep 17. Epub 2014 Sep 17. PMID: 25231862
Study Type : Animal Study, Human Study
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Pubmed Data : J Neuropathol Exp Neurol. 1996 Nov;55(11):1115-23. PMID: 8939194
Study Type : Human Study
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Diseases : Brain Cancer
Problem Substances : Aspartame
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Pubmed Data : Clin J Am Soc Nephrol. 2010 Sep 30. Epub 2010 Sep 30. PMID: 20884773
Study Type : Human Study
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Pubmed Data : Am J Clin Nutr. 2012 Oct 24. Epub 2012 Oct 24. PMID: 23097267
Study Type : Human Study
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Carcinogenic
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Pubmed Data : Clin Exp Rheumatol. 2012 Jul 4. Epub 2012 Jul 4. PMID: 22766026
Study Type : Human Study
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Pubmed Data : Ann Pharmacother. 2001 Jun;35(6):702-6. PMID: 11408989
Study Type : Human Study
Additional Links
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Pubmed Data : Eur J Pediatr. 2012 Mar 30. Epub 2012 Mar 30. PMID: 22457081
Study Type : Human: Case Report
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Pubmed Data : Endocrinol Nutr. 2015 Mar ;62(3):114-22. Epub 2015 Feb 11. PMID: 25681123
Study Type : Animal Study
Additional Links
Additional Keywords : Cytokines
Problem Substances : Aspartame
Adverse Pharmacological Actions : Immunoreactive, Oxidant
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Pubmed Data : Am J Ind Med. 2010 Sep 30. Epub 2010 Sep 30. PMID: 20886530
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Carcinogenic
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Pubmed Data : In Vivo. 2007 Jan-Feb;21(1):89-92. PMID: 17354619
Study Type : Animal Study
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Diseases : Cancers: All
Problem Substances : Aspartame
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Pubmed Data : Int J Immunopathol Pharmacol. 2015 Jun ;28(2):247-55. Epub 2015 May 26. PMID: 26015492
Study Type : Animal Study
Additional Links
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : PLoS One. 2012 ;7(4):e31570. Epub 2012 Apr 3. PMID: 22509243
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Neurotoxic
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Pubmed Data : Life Sci. 1998;63(5):337-49. PMID: 9714421
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
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Pubmed Data : Nutr Metab (Lond). 2012 Jun 14 ;9(1):58. Epub 2012 Jun 14. PMID: 22697049
Study Type : Animal Study
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Adverse Pharmacological Actions : Diabetogenic, Endocrine Disruptor: Insulin Resistance
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Pubmed Data : Drug Chem Toxicol. 2012 Mar 2. Epub 2012 Mar 2. PMID: 22385158
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Neurotoxic
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e109841. Epub 2014 Oct 14. PMID: 25313461
Study Type : Animal Study
Additional Links
Additional Keywords : Increased Risk, Microbiota
Problem Substances : Aspartame
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Pubmed Data : Food Chem Toxicol. 2008 Jun;46(6):2074-9. Epub 2008 Feb 8. PMID: 18343556
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2006 Mar;114(3):379-85. PMID: 16507461
Study Type : Animal Study
Additional Links
Diseases : Leukemia, Lymphoma
Problem Substances : Aspartame
Adverse Pharmacological Actions : Carcinogenic
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Pubmed Data : Food Chem Toxicol. 2007 Dec;45(12):2397-401. Epub 2007 Jun 16. PMID: 17673349
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
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Pubmed Data : J Basic Clin Physiol Pharmacol. 2015 Aug 6. Epub 2015 Aug 6. PMID: 26247507
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Oxidant
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Pubmed Data : Cell Biol Toxicol. 2002;18(1):43-50. PMID: 11991085
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame, Formaldehyde, Formate
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Pubmed Data : Ann N Y Acad Sci. 2006 Sep;1076:559-77. PMID: 17119233
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
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Pubmed Data : Arch Oral Biol. 2013 Sep ;58(9):1116-22. Epub 2013 Apr 28. PMID: 23631998
Study Type : Animal Study
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Diseases : Dental Caries
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Pubmed Data : J Biosci. 2012 Sep ;37(4):679-88. PMID: 22922192
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Neurotoxic
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2007 Sep;115(9):1293-7. PMID: 17805418
Study Type : Animal Study
Additional Links
Diseases : Leukemia, Lymphoma
Problem Substances : Aspartame
Adverse Pharmacological Actions : Carcinogenic
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Pubmed Data : Food Chem Toxicol. 2011 Jun ;49(6):1203-7. Epub 2011 Mar 3. PMID: 21376768
Study Type : Animal Study
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Problem Substances : Aspartame
Adverse Pharmacological Actions : Glutathione Down-Regulation, Hepatotoxic, Oxidant
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Pubmed Data : Ultrastruct Pathol. 2014 May ;38(3):224-36. Epub 2014 Mar 31. PMID: 24684500
Study Type : Animal Study
Additional Links
Substances : Anise
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Essential Oils
Problem Substances : Aspartame
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2013 Jun 19 ;10(1):44. Epub 2013 Jun 19. PMID: 23783067
Study Type : Transgenic Animal Study
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Diseases : Prediabetes
Adverse Pharmacological Actions : Diabetogenic
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Pubmed Data : Appetite. 2012 Oct 19. Epub 2012 Oct 19. PMID: 23088901
Study Type : Animal Study
Additional Links
Problem Substances : Aspartame, Saccharin
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biosci. 2014 Dec ;39(5):859-66. PMID: 25431414
Study Type : Animal Study
Additional Links
Additional Keywords : Increased Risk
Problem Substances : Aspartame
Adverse Pharmacological Actions : Oxidant
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Pubmed Data : Environ Sci Technol. 2014 Dec 2 ;48(23):13668-74. Epub 2014 Nov 14. PMID: 25365516
Study Type : Environmental
Additional Links
Additional Keywords : Environmental Pollutant
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Pubmed Data : Toxicol Sci. 2006 Mar;90(1):178-87. Epub 2005 Dec 13. PMID: 16352620
Study Type : In Vitro Study
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Pubmed Data : Med Hypotheses. 2010 Mar;74(3):493-6. Epub 2009 Nov 5. PMID: 19896282
Study Type : Commentary
Additional Links
Problem Substances : Aspartame
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Pubmed Data : Dermatitis. 2008 May-Jun;19(3):E10-1. PMID: 18627677
Study Type : Commentary
Additional Links
Problem Substances : Aspartame
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Pubmed Data : Eur J Clin Nutr. 2008 Apr;62(4):451-62. Epub 2007 Aug 8. PMID: 17684524
Study Type : Review
Additional Links
Problem Substances : Aspartame
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Pubmed Data : Pharmacol Res. 2006 Jan;53(1):1-5. Epub 2005 Aug 29. PMID: 16129618
Study Type : In Vitro Study
Additional Links
Problem Substances : Aspartame
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2016 Jul ;23(4):503-6. Epub 2015 Jun 15. PMID: 27298583
Study Type : In Vitro Study
Additional Links
Diseases : Cervical Cancer
Additional Keywords : Disease Progression, Risk Factors
Problem Substances : Aspartame
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Pubmed Data : Drug Chem Toxicol. 2008;31(4):447-57. PMID: 18850355
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
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Pubmed Data : Int J Occup Environ Health. 2007 Oct-Dec;13(4):446-8. PMID: 18085058
Study Type : Commentary
Additional Links
Problem Substances : Aspartame
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Pubmed Data : J Pharmacol Sci. 2003 Jan;91(1):83-6. PMID: 12686735
Study Type : In Vitro Study
Additional Links
Problem Substances : Aspartame, Formaldehyde, Methanol
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Pubmed Data : Mol Cells. 2011 May ;31(5):461-70. Epub 2011 Apr 21. PMID: 21533907
Study Type : In Vitro Study
Additional Links
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Pubmed Data : Drug Chem Toxicol. 2015 ;38(3):318-27. Epub 2014 Oct 15. PMID: 25317478
Study Type : In Vitro Study
Additional Links
Additional Keywords : Increased Risk
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Pubmed Data : Physiol Behav. 2016 Apr 14. Epub 2016 Apr 14. PMID: 27090230
Study Type : Bacterial
Additional Links
Additional Keywords : Microbiota, Risk Factors
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Pubmed Data : Biomarkers. 2006 Jan-Feb;11(1):14-27. PMID: 16484134
Study Type : Commentary
Additional Links
Problem Substances : Aspartame, Benzene
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Pubmed Data : Folia Neuropathol. 2013 ;51(1):10-7. PMID: 23553132
Study Type : Review
Additional Links
Problem Substances : Aspartame
Adverse Pharmacological Actions : Carcinogenic

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Aspartame-Related Blogs

Women are now almost twice as likely to be on antidepressants as men. Why?
Written by Sayer Ji, Founder
Promoted for decades as a "safe" sugar alternative, presumably to prevent or reduce symptoms of diabetes, Splenda (sucralose) has been found to have diabetes-promoting effects in human subjects.
Written by Anne Gordon, RN
You’ve heard a lot about aspartame by now, the synthetic sweetener found in many diet soft drinks, thousands of foods and supplements. But when you realize that aspartame is the excrement of GM bacteria (E Coli bacteria)….it makes a controversial product seem less healthy.
Written by Sayer Ji, Founder
Fibromyalgia, a condition characterized by chronic, body-wide pain, can be remedied with very simple dietary changes, and natural supportive remedies that have been clinically proven to have value.
Is your yogurt damaging your health? Are these highly processed ingredients in your grocery store yogurt?
Written by Sayer Ji, Founder
A groundbreaking new study reveals that non-caloric artificial sweeteners (NAS) drive obesity- and diabetes-related changes in both mice and humans.
Avoid these sugar substitutes for breast cancer healing, prevention and a healthy, chemical-free lifestyle.
Written by Anne Gordon, RN
Will aspartame in our milk be the new attractive 'diet' drink? The latest debate with letting you know what is in the food consumed is designed to make milk the new attractive 'diet' drink, along with many milk products.
Written by Sayer Ji, Founder
The #1 Children's vitamin brand in the US contains ingredients that most parents would never intentionally expose their children to, so why aren't more opting for healthier alternatives?
Written by Sayer Ji, Founder
A new study published this month in the journal Appetite revealed that when rats were given the synthetic sweeteners saccharin and aspartame, compared to sucrose (table sugar), they gained more weight even at similar total caloric intake levels
Written by Sayer Ji, Founder
A newly published study is destined to reignite the decades old controversy about aspartame's safety, or lack thereof. Aspartame converts to formaldehyde and formic acid, which are highly toxic to the body, but the nervous system in particular.
There are far too many people from every walk of life who do not know what Codex is, where guidelines and standards are set for the World for what we will eat and drink. Even many health care professionals only have a hazy understanding how Codex affects our health! Too many people needlessly feel impotent to take their power back and create positive changes toward health and health freedom.
Written by Sayer Ji, Founder
Is Splenda really a food, or a highly toxic chemical?
Written by Sayer Ji, Founder
Sugar and artificial sweeteners are so accessible, affordable and socially sanctioned, that few consider their habitual consumption to be a problem on the scale of say, addiction to cocaine. But if recent research is correct, their addictive potential could be even worse.
Written by Sayer Ji, Founder
So, you are looking to lose a few pounds, or keep them off. What better way to accomplish this feat than to eliminate both empty sugar calories and synthetic sweeteners, which studies show can generate excessive cravings for sweets and actually increase weight gain.
Written by Anne Gordon, RN
Known as NutraSweet or Equal, Aspartame, is an artificial sweetener, and is 180 times as sweet as sugar. Present in over 6000 products, Aspartame itself does not occur naturally. It was discovered in 1965 and approved by the FDA in 1981. Many researchers have linked a host of health problems, including brain diseases, migraines and neurological ailments to Aspartame.
Written by Sayer Ji, Founder
Pushed globally as a beneficial to dieters since its approval in 1981, accumulating research indicates that aspartame may actually damage the brain and cause cancer, to name but a few of a wide range of adverse health effects consumers risk by using this 'no-calorie' sugar alternative.
Despite warnings about the risks of chemicals in diet sodas, many people still rely on their daily Coke Zero. They take the risk because their greater concern is weight control. The sad irony is that diet sodas may actually be adding inches to their waistlines.
The FDA claims aspartame is safe. Researchers claim it causes memory loss, mood changes, and depression. Who are you going to believe?
Written by Sayer Ji, Founder
A concerning new study finds that most of the breast milk samples tested contained artificial sweeteners. Why has this never been discovered until now and what are the implications to our most vulnerable populations?

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