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Boric Acid

Boric Acid

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Article Count - 23
Cumulative Knowledge - 44

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View the Evidence: Problem Substances

A dose of 250 mg/kg/day of boric acid is associated with severe developmental toxicity in rabbits.

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Pubmed Data : Fundam Appl Toxicol. 1996 Dec;34(2):176-87. PMID: 8954748

Article Published Date : Dec 01, 1996

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid adversely effects early processes in embryogenesis.

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Pubmed Data : Reprod Toxicol. 2002 May-Jun;16(3):237-43. PMID: 12128096

Article Published Date : May 01, 2002

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid adversely effects embryonic development and mortality in rats.

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Pubmed Data : Biol Trace Elem Res. 1998;66(1-3):373-94. PMID: 10050931

Article Published Date : Jan 01, 1998

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid enhances the growth of a cancer cell line in mice.

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Pubmed Data : Toxicology. 2001 Aug 13;165(1):1-11. PMID: 11551427

Article Published Date : Aug 13, 2001

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid exhibits estrogen-like effects in vivo.

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Pubmed Data : Biol Trace Elem Res. 2008 Feb;121(2):160-70. Epub 2007 Oct 18. PMID: 17943231

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid exhibits teratogenicity (birth defect).

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Pubmed Data : Toxicol Appl Pharmacol. 2007 Apr 15;220(2):178-85. Epub 2007 Jan 12. PMID: 17320131

Article Published Date : Apr 15, 2007

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid exhibits testicular toxicity in male rats - Article 2.

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Pubmed Data : J Toxicol Sci. 2000 Oct;25 Spec No:223-32. PMID: 11349447

Article Published Date : Oct 01, 2000

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid exhibits testicular toxicity in male rats.

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Pubmed Data : J Toxicol Sci. 2000 Oct;25 Spec No:233-9. PMID: 11349449

Article Published Date : Oct 01, 2000

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid exhibits toxicity in trout and zebrafish embryos.

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Pubmed Data : Biol Trace Elem Res. 1998;66(1-3):261-70. PMID: 10050924

Article Published Date : Jan 01, 1998

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid in combination with hyperthermia leads to skeletal defects in rat embryos.

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Pubmed Data : Birth Defects Res B Dev Reprod Toxicol. 2005 Jun;74(3):268-76. PMID: 15954087

Article Published Date : Jun 01, 2005

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid induces oxidative stress and effects survivorship in the larvae of the wax moth.

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Pubmed Data : Arch Insect Biochem Physiol. 2007 Sep;66(1):23-31. PMID: 17694562

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid is associated with developmental toxicity in mice, rats and rabbits.

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Pubmed Data : Environ Health Perspect. 1994 Nov;102 Suppl 7:107-12. PMID: 7889869

Article Published Date : Nov 01, 1994

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid is capable of generating male reproductive toxicities in rats.

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Pubmed Data : J Toxicol Sci. 1999 Aug;24(3):199-208. PMID: 10478334

Article Published Date : Aug 01, 1999

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid is used as an insecticide against adult mosquitoes - Article 2.

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Pubmed Data : J Am Mosq Control Assoc. 2006 Sep;22(3):497-500. PMID: 17067052

Article Published Date : Sep 01, 2006

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid is used as an insecticide against adult mosquitoes.

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Pubmed Data : J Econ Entomol. 2003 Oct;96(5):1559-62. PMID: 14650531

Article Published Date : Oct 01, 2003

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid is used as an insecticide against cockroaches - Article 2.

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Pubmed Data : J Econ Entomol. 2003 Aug;96(4):1362-6. PMID: 14503613

Article Published Date : Aug 01, 2003

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid is used as an insecticide against cockroaches.

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Pubmed Data : J Econ Entomol. 2004 Jun;97(3):1009-16. PMID: 15279285

Article Published Date : Jun 01, 2004

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid leads to developmental toxicity both in the presence of maternal toxicity and below maternally toxic levels in rats.

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Pubmed Data : Fundam Appl Toxicol. 1992 Feb;18(2):266-77. PMID: 1601227

Article Published Date : Feb 01, 1992

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid may contribute to developmental toxicity in rats.

Click here to read the entire abstract

Pubmed Data : Fundam Appl Toxicol. 1996 Aug;32(2):179-93. PMID: 8921321

Article Published Date : Aug 01, 1996

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid-exposed rat embryos show defects in their cervical vertebrae.

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Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2003 Jan;67(1):59-67. PMID: 12749385

Article Published Date : Jan 01, 2003

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Subacute boric acid administration has an adverse effect on rat kidney tissue.

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Pubmed Data : Clin Toxicol (Phila). 2006;44(3):249-53. PMID: 16749541

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23)

Boric acid and Diphenhydramine (Benadryl) exhibit embryotoxic activity.

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Pubmed Data : Toxicol Sci. 2008 Oct;105(2):342-50. Epub 2008 Jun 30. PMID: 18593728

Article Published Date : Oct 01, 2008

Study Type : In Vitro Study

Additional Links

Problem Substances : Boric Acid : CK(44) : AC(23), Diphenhydramine : CK(72) : AC(9)

Five food preservatives exhibit genotoxicity in a plant model.

Click here to read the entire abstract

Pubmed Data : Mutat Res. 2007 Jan 10;626(1-2):4-14. Epub 2006 Sep 26. PMID: 17005441

Article Published Date : Jan 10, 2007

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293)

Problem Substances : Boric Acid : CK(44) : AC(23), Citric acid : CK(1) : AC(1), Food Preservatives : CK(1) : AC(1), Potassium citrate : CK(1) : AC(1), Sodium Benzoate : CK(202) : AC(16), Sodium Citrate : CK(1) : AC(1)

Adverse Pharmacological Actions : Genotoxic : CK(146) : AC(61)

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