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Article Count - 16
Cumulative Knowledge - 166

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Quick Summary: Current access displays 2 out of 25 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Atrial Fibrillation	20	1	Log in \| Sign up
COPD	20	2	Log in \| Sign up

Quick Summary: Current access displays 2 out of 4 associated Adverse Pharmacological Actions

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Cardiotoxic	20	1	Log in \| Sign up
Endocrine Disruptor	10	1	Log in \| Sign up

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View the Evidence: Problem Substances

Corticosteroid injections have no intermediate or long-term benefits in treating tendinopathy.

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Pubmed Data : Lancet. 2010 Nov 20 ;376(9754):1751-67. Epub 2010 Oct 21. PMID: 20970844

Article Published Date : Nov 20, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Tendinopathy : CK(53) : AC(5)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Corticosteroids increase the risk of atrial fibrillation.

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Pubmed Data : Arch Intern Med. 2006 May 8;166(9):1016-20. PMID: 16682576

Article Published Date : May 08, 2006

Study Type : Meta Analysis

Additional Links

Diseases : Atrial Fibrillation : CK(441) : AC(45)

Problem Substances : Corticosteroid : CK(166) : AC(16), Prednisone : CK(152) : AC(17)

Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79)

Pimecrolimus, tacrolimus and medium- to high-potency corticosteroids use is associated with increased lymphoma rates relative to the general population.

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Pubmed Data : Dermatology. 2009;219(1):7-21. Epub 2009 Mar 17. PMID: 19293564

Article Published Date : Jan 01, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Drug-Induced Toxicity : CK(560) : AC(78), Lymphoma : CK(209) : AC(69)

Problem Substances : Corticosteroid : CK(166) : AC(16), Pimecrolimus (trade name Elidel) : CK(30) : AC(2), Tacrolimus : CK(21) : AC(2)

Corticosteroid injections have been associated with symptomatic spinal epidural lipomatosis.

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Pubmed Data : Neurosurgery. 1999 Jul;45(1):162-5. PMID: 10414580

Article Published Date : Jul 01, 1999

Study Type : Human Study

Additional Links

Diseases : Lipomatosis : CK(10) : AC(2)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Corticosteroid treatment are associated with mood and cognitive changes that are not unlike those associated with bipolar disorder.

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Pubmed Data : Ann N Y Acad Sci. 2009 Oct;1179:41-55. PMID: 19906231

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Diseases : Bipolar Disorder : CK(158) : AC(18)

Additional Keywords : Iatrogenic Disease : CK(226) : AC(26)

Problem Substances : Corticosteroid : CK(166) : AC(16), Dexamethasone : CK(49) : AC(8), Prednisone : CK(152) : AC(17)

Corticosteroids contribute to muscle weakness in Cystic Fibrosis patients.

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Pubmed Data : J Appl Physiol. 2003 Oct;95(4):1379-84. Epub 2003 Jun 13. PMID: 12807896

Article Published Date : Oct 01, 2003

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis : CK(703) : AC(77)

Problem Substances : Corticosteroid : CK(166) : AC(16), Hydrocortisone : CK(30) : AC(3), Prednisone : CK(152) : AC(17)

Corticosteroids do not obviate the need for subsequent interventions such as additional root blocks or surgery in patients with pain associated with lumbar disc herniation or lumbar spinal stenosis.

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Pubmed Data : Eur Spine J. 2009 Aug;18(8):1220-5. Epub 2009 Apr 22. PMID: 19387704

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Diseases : Disc Herniation : CK(30) : AC(3), Spinal Stenosis : CK(30) : AC(3)

Problem Substances : Bupivacaine : CK(10) : AC(1), Corticosteroid : CK(166) : AC(16), Methylprednisolone : CK(11) : AC(2)

Distant discitis and vertebral osteomyelitis involving skip levels and without the occurrence of epidural abscess formation is a serious but rare complication after epidural injection.

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Pubmed Data : Spine (Phila Pa 1976). 2003 Jun 1;28(11):E209-11. PMID: 12782996

Article Published Date : Jun 01, 2003

Study Type : Human Study

Additional Links

Diseases : Low Back Pain : CK(234) : AC(24), Osteomyelitis : CK(43) : AC(6)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Inhaled corticosteroid use is associated with increased risk of pneumonia in patients with COPD.

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Pubmed Data : Curr Opin Pulm Med. 2010 Mar;16(2):118-22. PMID: 19926996

Article Published Date : Mar 01, 2010

Study Type : Human Study

Additional Links

Diseases : COPD : CK(158) : AC(18), Pneumonia : CK(330) : AC(40)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Steroid treatment in idiopathic thrombocytopenic purpura has been associated with avascular necrosis of the hip and knee.

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Pubmed Data : Intern Med. 2008;47(22):1989-92. Epub 2008 Nov 17. PMID: 19015614

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Diseases : Avascular Necrosis of Bone : CK(10) : AC(1), Purpura: Thrombocytopenic : CK(800) : AC(24), Steroid-Induced Toxicity : CK(24) : AC(9)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Systemic corticosteroid use suppresses the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.

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Pubmed Data : BMC Pulm Med. 2008;8:1. Epub 2008 Jan 26. PMID: 18221550

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Diseases : COPD : CK(158) : AC(18), HPA Axis Dysregulation : CK(71) : AC(11)

Problem Substances : Corticosteroid : CK(166) : AC(16), Dexamethasone : CK(49) : AC(8), Prednisone : CK(152) : AC(17)

Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81)

There is insufficient evidence to support the use of injection therapy in subacute and chronic low-back pain.

Click here to read the entire abstract

Pubmed Data : Spine (Phila Pa 1976). 2009 Jan 1;34(1):49-59. PMID: 19127161

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Low Back Pain : CK(234) : AC(24)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Topical steroids used in the diaper area may cause immunosuppression and subsequent infection and Cushing's syndrome.

Click here to read the entire abstract

Pubmed Data : Pediatr Dermatol. 2008 Sep-Oct;25(5):544-7. PMID: 18950396

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Diseases : Corticosteroid-Induced Toxicity : CK(78) : AC(17), Eczema: Infant : CK(171) : AC(15)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Spontaneous skin tearing during systemic corticosteroid treatment has been reported.

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Pubmed Data : JAMA. 1980 Mar 28;243(12):1260-1. PMID: 7359683

Article Published Date : Mar 28, 1980

Study Type : Human: Case Report

Additional Links

Diseases : Aging Skin : CK(360) : AC(86), Rheumatoid Arthritis : CK(424) : AC(64), Skin: Thinning : CK(3) : AC(1)

Problem Substances : Corticosteroid : CK(166) : AC(16), Prednisone : CK(152) : AC(17)

Prednisone reduces total T4 levels in hypothyroid dogs.

Click here to read the entire abstract

Pubmed Data : Vet Dermatol. 2010 Nov 11. Epub 2010 Nov 11. PMID: 21070400

Article Published Date : Nov 11, 2010

Study Type : Animal Study

Additional Links

Diseases : Corticosteroid-Induced Toxicity : CK(78) : AC(17), Hypothyroidism : CK(537) : AC(78)

Problem Substances : Corticosteroid : CK(166) : AC(16), Prednisone : CK(152) : AC(17)

Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid : CK(67) : AC(14), Thyroid Suppressive : CK(18) : AC(5)

Report: Hypoglycemia due to adrenal suppression secondary to high-dose nebulized corticosteroid.

Click here to read the entire abstract

Pubmed Data : Pediatr Pulmonol. 2002 Jul;34(1):85-6. PMID: 12112803

Article Published Date : Jul 01, 2002

Study Type : Commentary

Additional Links

Diseases : Acquired hypogammaglobulinemia : CK(81) : AC(8), Asthma : CK(918) : AC(134)

Problem Substances : Corticosteroid : CK(166) : AC(16)

Related Blogs

Do Cortisone Shots Make Things Worse?

Written by Dr. Peter Braglia

A major article review published in The Lancet in 2010 revealed what many in the natural health profession have suspected for a long time. The review examined the results of over 41 randomized trials and over 2500 patients with tendon injuries. The reviewers found that cortisone injections did in fact provide fast and significant pain relief compared with doing nothing or partaking in physical therapy. However, cortisone shots did not heal the structural damage underlying the pain.

Science Confirms Turmeric As Effective As 14 Drugs

Written by Sayer Ji, Founder

Turmeric is one the most thoroughly researched plants in existence today. Its medicinal properties and components (primarily curcumin) have been the subject of over 5600 peer-reviewed and published biomedical studies.

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