Cow Milk

Cow Milk

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View the Evidence: Problem Substances

The beta-casein A1 protein variant of cow's milk may contribute to increased risk of diabetes type 1.

Pubmed Data : Diabetologia. 1999 Mar;42(3):292-6. PMID: 10096780
Article Published Date : Mar 01, 1999
Study Type : Meta Analysis
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30)
Problem Substances : Beta-casomorphin-7 : CK(26) : AC(6), Casein : CK(135) : AC(16)

The consumption of cow milk A1 beta-casein is associated with increased risk of ischaemic heart disease and type 1 diabets.

Pubmed Data : N Z Med J. 2003 Jan 24;116(1168):U295. Epub 2003 Jan 24. PMID: 12601419
Article Published Date : Jan 24, 2003
Study Type : Meta Analysis
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30), Heart Disease: Ischemic : CK(201) : AC(16)
Problem Substances : Casein : CK(135) : AC(16), Casein: A1 : CK(44) : AC(7)
Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79)

There exists convincing data supporting the role of dairy products and high-glycemic-index foods in influencing hormonal and inflammatory factors, which can increase acne prevalence and severity.

Pubmed Data : Skin Therapy Lett. 2010 Mar ;15(3):1-2, 5. PMID: 20361171
Article Published Date : Feb 28, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Acne : CK(198) : AC(32)
Therapeutic Actions : Dietary Modification: Cow's Milk/Casein Free : CK(43) : AC(2), Dietary Modification: Low Glycemic Load : CK(10) : AC(1)
Problem Substances : Cow Milk : CK(368) : AC(46), Foods: High Glycemic Load : CK(10) : AC(1)

There is evidence supporting the beneficial effect of a gluten- and casein-free diet for autistic spectrum disorder.

Pubmed Data : Cochrane Database Syst Rev. 2004(2):CD003498. PMID: 15106205
Article Published Date : Jan 01, 2004
Study Type : Meta Analysis
Additional Links
Diseases : Autism Spectrum Disorders : CK(1140) : AC(108)
Therapeutic Actions : Dietary Modification: Cow's Milk/Casein Free : CK(43) : AC(2), Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Problem Substances : Casein : CK(135) : AC(16), Gluten : CK(1755) : AC(144)

"A 6-food elimination diet (SFED) excluding cow's milk, soy, wheat, egg, peanuts/tree nuts, and seafood has been shown to induce remission in a majority of children with EoE."

Pubmed Data : J Pediatr Gastroenterol Nutr. 2011 Aug ;53(2):145-9. PMID: 21788754
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Diseases : Eosinophilic esophagitis : CK(66) : AC(5)
Problem Substances : Cow Milk : CK(368) : AC(46), Egg : CK(20) : AC(3), Peanut : CK(31) : AC(5), Soy : CK(56) : AC(8), Wheat : CK(2542) : AC(309)

A Gluten and casein-free diet may have a therapeutic effect in autism spectrum and attention deficit disorders.

Pubmed Data : Nutr Neurosci. 2010 Apr;13(2):87-100. PMID: 20406576
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder : CK(134) : AC(12), Attention Deficit Disorder with Hyperactivity : CK(240) : AC(30), Autism Spectrum Disorders : CK(1140) : AC(108)
Additional Keywords : Gluten and ADHD : CK(20) : AC(2)
Problem Substances : Casein : CK(135) : AC(16), Gluten : CK(1755) : AC(144)

A study of 53 pediatric patients with eosinophilic esophagitis found most were highly atopic with frequent allergic sensitivities; the overall prevalence of food & inhalant sensitization was 80%, with higher total IgE levels in sensitized vs nonsensitized

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Allergy Asthma Immunol. 2010 Jun ;104(6):496-502. PMID: 20568382
Article Published Date : May 31, 2010
Study Type : Human Study
Additional Links
Diseases : Eosinophilic esophagitis : CK(66) : AC(5), Food Allergies : CK(420) : AC(57), IgE-Mediated Hypersensitivity : CK(108) : AC(2)
Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)
Problem Substances : Cow Milk : CK(368) : AC(46), Rye : CK(12) : AC(3), Soy : CK(56) : AC(8), Wheat : CK(2542) : AC(309)

A variety of dietary factors may contribute to increased risk for leukemia.

Pubmed Data : Eur J Cancer Prev. 1993 Mar;2(2):139-46. PMID: 8461864
Article Published Date : Mar 01, 1993
Study Type : Human Study
Additional Links
Diseases : Acute lymphoblastic leukemia (ALL) : CK(96) : AC(29), Acute Myeloid Leukemia : CK(51) : AC(20), Leukemia : CK(670) : AC(258)
Problem Substances : Cow Milk : CK(368) : AC(46), Meat : CK(83) : AC(7), Poultry : CK(10) : AC(1)
Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Approximately 1 in every 3 patients with atopic eczema are positive for anti-gliadin and/or anti-milk antibodies, indicating they may play a causitive role in the disease.

Pubmed Data : Clin Exp Dermatol. 1985 May;10(3):222-8. PMID: 4006283
Article Published Date : May 01, 1985
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis : CK(667) : AC(80)
Problem Substances : Cow Milk : CK(368) : AC(46), Gliadin : CK(2509) : AC(110)
Adverse Pharmacological Actions : Immunoreactive : CK(127) : AC(17)

Bovine alpha 1 casein that is considered a major cow's milk allergen is readily secreted in human milk.

Pubmed Data : J Biol Regul Homeost Agents. 2012 Jul-Sep;26(3 Suppl):39-42. PMID: 23158513
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Diseases : Allergy: Cow's Milk : CK(92) : AC(18), Breastfeeding: Complications : CK(187) : AC(20), Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15)
Problem Substances : Bovine alpha-S1-casein : CK(10) : AC(1), Casein : CK(135) : AC(16)

Children with atopic dermatitis commonly have specif IgE to common food allergens.

Pubmed Data : Iran J Immunol. 2012 Mar ;9(1):32-8. PMID: 22426165
Article Published Date : Mar 01, 2012
Study Type : Human Study
Additional Links
Diseases : Allergy: Cow's Milk : CK(92) : AC(18), Atopic Dermatitis: Infant & Childhood : CK(170) : AC(14), Food Allergies : CK(420) : AC(57), Food Allergies/Intolerances: Cereals/Grains : CK(11) : AC(2), Food Allergies: Wheat : CK(366) : AC(47), Nightshade Foods Intolerance : CK(10) : AC(1)
Problem Substances : Cow Milk : CK(368) : AC(46), Egg : CK(20) : AC(3), Nuts : CK(10) : AC(1), Peanut : CK(31) : AC(5), Potato : CK(43) : AC(11), Tomato : CK(10) : AC(1), Wheat : CK(2542) : AC(309)
Adverse Pharmacological Actions : Immunoreactive : CK(127) : AC(17)

Consumption of cow's milk is a cause of iron deficiency in infants and toddlers.

Pubmed Data : Nutr Rev. 2011 Nov ;69 Suppl 1:S37-42. PMID: 22043881
Article Published Date : Nov 01, 2011
Study Type : Human Study
Additional Links
Diseases : Allergy: Cow's Milk : CK(92) : AC(18), Anemia: Iron Deficiency : CK(85) : AC(11), Casein Intolerance : CK(44) : AC(5)
Problem Substances : Cow Milk : CK(368) : AC(46)

Cow's milk protein antibodies are a risk factor for childhood insulin-dependent diabetes mellitus.

Pubmed Data : Diabetologia. 1998 Jan;41(1):72-8. PMID: 9498633
Article Published Date : Jan 01, 1998
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases : CK(5317) : AC(779), Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30)
Additional Keywords : Cow's Milk - Diabetes Type 1 Link : CK(10) : AC(1)
Problem Substances : Cow Milk : CK(368) : AC(46), Infant Formula : CK(485) : AC(63)

Elevated IgA antibodies to gluten and gliadin proteins and to casein in milk have been found in patients with Rett syndrome.

Pubmed Data : Autism. 2006 Mar;10(2):189-97. PMID: 16613867
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Diseases : Casein Intolerance : CK(44) : AC(5), Gluten Intolerance : CK(236) : AC(33), Rett Syndrome : CK(20) : AC(2), Wheat Intolerance : CK(2480) : AC(231)
Problem Substances : Casein : CK(135) : AC(16), Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144)

Gastroesophageal reflux in infants resistant to drug treatment responds favorably to the elimination of cow's milk.

Pubmed Data : Gut Liver. 2011 Sep ;5(3):298-301. Epub 2011 Aug 18. PMID: 21927657
Article Published Date : Sep 01, 2011
Study Type : Human Study
Additional Links
Diseases : Allergy: Cow's Milk : CK(92) : AC(18), Gastroesophageal Reflux : CK(278) : AC(41), Gastroesophageal Reflux: Infant and Children : CK(30) : AC(3)
Problem Substances : Cow Milk : CK(368) : AC(46)

Highly significant increases compared with controls were found in patients with multiple sclerosis for IgA and IgG antibodies against gliadin and gluten and IgA antibodies against casein.

Pubmed Data : Acta Neurol Scand. 2004 Oct;110(4):239-41. PMID: 15355487
Article Published Date : Oct 01, 2004
Study Type : Human Study
Additional Links
Diseases : Casein Intolerance : CK(44) : AC(5), Gluten Intolerance : CK(236) : AC(33), Multiple Sclerosis : CK(716) : AC(133)
Problem Substances : Casein : CK(135) : AC(16), Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Insulin-free whey-based cow's milk formula is associated with lower incidence of beta cell autoimmunity in infants and young children..

Pubmed Data : Arch Pediatr Adolesc Med. 2012 Mar 5. Epub 2012 Mar 5. PMID: 22393174
Article Published Date : Mar 05, 2012
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218)
Problem Substances : Cow Milk : CK(368) : AC(46), Insulin : CK(92) : AC(15)

Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia.

Pubmed Data : Ann Nutr Metab. 2006;50(3):177-83. Epub 2006 Jan 10. PMID: 16407643
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)
Problem Substances : Casein : CK(135) : AC(16), Casein: A1 : CK(44) : AC(7)

Milk and bacterial proteins may produce neuron-specific antigens in children with autism.

Pubmed Data : J Neuroimmunol. 2002 Aug;129(1-2):168-77. PMID: 12161033
Article Published Date : Aug 01, 2002
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders : CK(1140) : AC(108), Autoimmune Diseases : CK(5317) : AC(779), Brain Inflammation : CK(79) : AC(35)
Additional Keywords : Molecular Mimicry : CK(47) : AC(10)
Problem Substances : Butyrophilin : CK(20) : AC(2), Chlamydia Pneumoniae : CK(10) : AC(1), Cow Milk : CK(368) : AC(46), Streptococcal M Protein : CK(10) : AC(1)
Adverse Pharmacological Actions : Immunoreactive : CK(127) : AC(17), Immunotoxic : CK(230) : AC(38), Neurotoxic : CK(1076) : AC(179)

Of 192 children 44 were allergic to cow's milk protein. From skin prick test, specific IgE test, atopy patch test & oral challenge; oral challege was determined the best diagnostic method for cow's milk protein allergy.

Pubmed Data : Pediatr Allergy Immunol. 2011 Feb ;22(1 Pt 2):e133-8. PMID: 21342278
Article Published Date : Jan 31, 2011
Study Type : Human Study
Additional Links
Diseases : Allergy: Cow's Milk : CK(92) : AC(18), Hypersensitivity: Immediate : CK(93) : AC(9), IgE-Mediated Hypersensitivity : CK(108) : AC(2)
Therapeutic Actions : Dietary Modification: Cow's Milk/Casein Free : CK(43) : AC(2)
Problem Substances : Cow Milk : CK(368) : AC(46)

Specific cow's milk proteins appear to have a role in the etiology of recurrent aphthous ulcers (canker sores).

Pubmed Data : J Oral Pathol Med. 2012 Aug 24. Epub 2012 Aug 24. PMID: 22924810
Article Published Date : Aug 23, 2012
Study Type : Human Study
Additional Links
Diseases : Canker Sore : CK(51) : AC(2), Recurrent aphthous ulcerations (RAU) : CK(31) : AC(3)
Problem Substances : Cow Milk : CK(368) : AC(46)

The beta-casein A1 protein variant of cow's milk may contribute to increased risk of diabetes type 1. - Article 2.

Pubmed Data : Diabetes Nutr Metab. 2002 Aug;15(4):240-5. PMID: 12416661
Article Published Date : Aug 01, 2002
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30)
Problem Substances : Casein : CK(135) : AC(16), Casein: A1 : CK(44) : AC(7), Cow Milk : CK(368) : AC(46)
Adverse Pharmacological Actions : Diabetogenic : CK(166) : AC(14)

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