Donepezil (trade name Aricept)

Donepezil (trade name Aricept)

User Options

Hover over an icon for more information

Jump to Articles

Article Count - 8

Click to Display Sorting Options

Limited to Members Only

By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by clicking here. If you do not currently have a user account, and would like to create one/become a member, click here to begin the singup process.

Currently Available Sorting Options

Article Published Date - Sort all displayed articles by their published date
Quick Summary Fieldsets - Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge - Default sorting method. Allows you to sort descendingly

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Click here for a more thorough explanation.

Quick Summary: Current access displays 2 out of 13 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Alzheimer's Disease	63	5	Log in \| Sign up
Bradycardia	43	3	Log in \| Sign up

Quick Summary: 1 associated Adverse Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Neurotoxic	23	3	Log in \| Sign up

Currently Viewing Free Sample of Member Only Features

Although all 18,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 2 rows, of the membership feature called "Cumulative Knowledge" (learn more).

The Focus Article Feature is not enabled.

Upgrading to the Member role gives you access to unlimited rows of Cumulative Knowledge data.

To Participate

Click here to login
Click here to create an account

View the Evidence: Problem Substances

21 percent of patients who receive donepezil discontinue treatment due to adverse side effects.

Click here to see the entire article

Pubmed Data : Ugeskr Laeger. 2009 Dec 7;171(50):3690-3. PMID: 20003864

Article Published Date : Dec 07, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Alzheimer's Disease : CK(837) : AC(165), Diarrhea: Drug-Associated : CK(22) : AC(2)

Problem Substances : Donepezil (trade name Aricept) : CK(89) : AC(8)

Cholinesterase inhibitor drug use is associated with increased incidence of bradycardia.

Click here to see the entire article

Pubmed Data : J Am Geriatr Soc. 2009 Nov;57(11):1997-2003. Epub 2009 Sep 28. PMID: 19793162

Article Published Date : Nov 01, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Alzheimer's Disease : CK(837) : AC(165), Bradycardia : CK(56) : AC(8), Dementia : CK(207) : AC(31)

Problem Substances : Cholinesterase Inhibitor Drugs : CK(135) : AC(9), Donepezil (trade name Aricept) : CK(89) : AC(8)

Donepezil and memantine are known to cause bradycardia and to reduce the epileptogenic threshold.

Click here to see the entire article

Pubmed Data : Therapie. 2010 May-Jun;65(3):255-9. Epub 2010 Aug 11. PMID: 20699079

Article Published Date : May 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Alzheimer's Disease : CK(837) : AC(165), Bradycardia : CK(56) : AC(8), Epileptic Seizures : CK(47) : AC(6)

Problem Substances : Donepezil (trade name Aricept) : CK(89) : AC(8), Memantine : CK(42) : AC(3)

The WHO reports 71,471 seizures from a variety of neuroactive drugs between 1968-2006.

Click here to see the entire article

Pubmed Data : Seizure. 2010 Mar;19(2):69-73. Epub 2009 Dec 24. PMID: 20036167

Article Published Date : Mar 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Seizures : CK(122) : AC(28)

Problem Substances : Amoxapine : CK(20) : AC(1), Buproprione : CK(20) : AC(1), Chlorprothiexene : CK(20) : AC(1), Clozapine : CK(20) : AC(1), Donepezil (trade name Aricept) : CK(89) : AC(8), Escitaloprame : CK(20) : AC(1), Maprotilene : CK(20) : AC(1), Quetiapine : CK(20) : AC(1), Rivastigmine : CK(21) : AC(2), Trimipramine : CK(20) : AC(1)

Adverse Pharmacological Actions : Neurotoxic : CK(1042) : AC(170)

A case of dementia with Lewy bodies showing cervical dystonia after donepezil administration has been reported.

Click here to see the entire article

Pubmed Data : Rinsho Shinkeigaku. 2010 Mar;50(3):147-50. PMID: 20235482

Article Published Date : Mar 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Cervical Dystonia : CK(3) : AC(1), Liver Failure: Drug Induced : CK(23) : AC(3)

Problem Substances : Donepezil (trade name Aricept) : CK(89) : AC(8)

Donepezil-associated bradyarrhythmia in a patient with dementia with Lewy bodies (DLB) has been reported.

Click here to see the entire article

Pubmed Data : Alzheimer Dis Assoc Disord. 2010 Apr-Jun;24(2):209-11. PMID: 20505440

Article Published Date : Apr 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Bradycardia : CK(56) : AC(8), Dementia : CK(207) : AC(31), Dementia with Lewy bodies (DLB) : CK(3) : AC(1)

Problem Substances : Donepezil (trade name Aricept) : CK(89) : AC(8)

Donepezil markedly potentiates memantine neurotoxicity.

Click here to see the entire article

Pubmed Data : Neurobiol Aging. 2008 Feb ;29(2):153-67. Epub 2006 Nov 16. PMID: 17112636

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Alzheimer's Disease : CK(837) : AC(165), Neurodegenerative Diseases : CK(1701) : AC(420)

Pharmacological Actions : Apoptotic : CK(1416) : AC(1089)

Additional Keywords : Drug Synergy : CK(324) : AC(144)

Problem Substances : Donepezil (trade name Aricept) : CK(89) : AC(8), Memantine : CK(42) : AC(3)

Adverse Pharmacological Actions : Neurotoxic : CK(1042) : AC(170)

The cholinesterase inhibitor drugs may increase tremor and exacerbation of Parkinson's disease.

Click here to see the entire article

Pubmed Data : Prescrire Int. 2007 Oct;16(91):197-8. PMID: 17926835

Article Published Date : Oct 01, 2007

Study Type : Review

Additional Links

Diseases : Alzheimer's Disease : CK(837) : AC(165), Dementia : CK(207) : AC(31), Parkinson Disease : CK(541) : AC(79), Parkinsonism : CK(12) : AC(8), Tremor : CK(39) : AC(8)

Problem Substances : Cholinesterase Inhibitor Drugs : CK(135) : AC(9), Donepezil (trade name Aricept) : CK(89) : AC(8), Galantamine : CK(1) : AC(1), Rivastigmine : CK(21) : AC(2)

Adverse Pharmacological Actions : Neurotoxic : CK(1042) : AC(170)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version