Fluoroquinolone Antibiotic

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View the Evidence: Problem Substances

Fluoroquinolone prescriptions for pneumonia are associated with longer delays in diagnosis and treatment of pulmonary TB and a higher risk of developing fluoroquinolone-resistant M. tuberculosis.

Pubmed Data : Int J Infect Dis. 2011 Mar;15(3):e211-6. Epub 2010 Dec 30. PMID: 21195001
Article Published Date : Mar 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Infection: Antibiotic Resistant : CK(303) : AC(88), Pulmonary Tubercolosis : CK(80) : AC(12)
Additional Keywords : Antibiotic Resistance : CK(56) : AC(7)
Problem Substances : Fluoroquinolone Antibiotic : CK(82) : AC(11)

Anti-infectives may increase the risk of severe hypoglycemia in glipizide or glyburide users.

Pubmed Data : Clin Pharmacol Ther. 2010 Aug;88(2):214-22. Epub 2010 Jun 30. PMID: 20592722
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Hypoglycemia : CK(274) : AC(21)
Additional Keywords : Drug-to-Drug Interactions : CK(10) : AC(1)
Problem Substances : Antibiotics : CK(180) : AC(19), Cephalexin : CK(10) : AC(1), Cipro : CK(47) : AC(8), Clarithromycin : CK(10) : AC(1), Co-trimoxazole : CK(10) : AC(1), Fluconazole : CK(10) : AC(1), Glipizide : CK(64) : AC(6), Glyburide : CK(50) : AC(4), Levofloxacin : CK(10) : AC(1)
Adverse Pharmacological Actions : Hypoglycemic : CK(12) : AC(2)

Ciprofloxacin, a fluoroquinolone antibacterial agent, is not recommended in pediatric population on account of its possible adverse effect on growing cartilage.

Pubmed Data : Indian Pediatr. 1992 Feb;29(2):181-8. PMID: 1592498
Article Published Date : Feb 01, 1992
Study Type : Human Study
Additional Links
Diseases : Childhood Infections : CK(275) : AC(29)
Problem Substances : Cipro : CK(47) : AC(8)

Ciprofloxacin-induced bone marrow depression has been reported.

Pubmed Data : Postgrad Med J. 1999 Sep;75(887):571-3. PMID: 10616701
Article Published Date : Sep 01, 1999
Study Type : Human Study
Additional Links
Diseases : Bone Marrow Suppression : CK(14) : AC(4), Myelotoxicity : CK(31) : AC(8)
Problem Substances : Cipro : CK(47) : AC(8)

Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study.

Pubmed Data : CMAJ. 2012 Aug 13. Epub 2012 Aug 13. PMID: 22891208
Article Published Date : Aug 12, 2012
Study Type : Human Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175)
Problem Substances : Fluoroquinolone Antibiotic : CK(82) : AC(11)
Adverse Pharmacological Actions : Hepatotoxic : CK(283) : AC(80)

Thrombocytopenia has been associated with intravenous ciprofloxacin.

Pubmed Data : Pharmacotherapy. 2005 Jul;25(7):1030-4. PMID: 16006282
Article Published Date : Jul 01, 2005
Study Type : Human Study
Additional Links
Diseases : Thrombocytopenia : CK(800) : AC(25)
Problem Substances : Cipro : CK(47) : AC(8), Fluoroquinolone Antibiotic : CK(82) : AC(11)

Reversible encephalopathy and delirium in patients with chronic renal failure who had received ciprofloxacin has been reported.

Pubmed Data : Saudi J Kidney Dis Transpl. 2002 Apr-Jun;13(2):163-70. PMID: 17660656
Article Published Date : Apr 01, 2002
Study Type : Human: Case Report
Additional Links
Diseases : Delirium: Drug-Induced : CK(26) : AC(6), Encephalopathies : CK(11) : AC(5)
Problem Substances : Cipro : CK(47) : AC(8)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Ciprofloxacin (Cipro) and ofloxacin exhibit myocardiotoxicity in the hearts of juvenile rats.

Pubmed Data : Drug Chem Toxicol. 2009;32(3):238-42. PMID: 19538020
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Cipro : CK(47) : AC(8), Ofloxacin : CK(2) : AC(1)

Fluoroquinolones retard fracture healing in rats.

Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2005 Jan;11(1):17-22. PMID: 15688263
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Bone Fractures : CK(1610) : AC(69), Hip Fracture : CK(1724) : AC(21)
Problem Substances : Fluoroquinolone Antibiotic : CK(82) : AC(11)

Cipro and related fluoroquinolone (FQ) antibiotics interfere with plant photosynthesis and cause morphological deformities in higher plants.

Pubmed Data : Environ Sci Technol. 2010 Feb 15;44(4):1444-50. PMID: 20070075
Article Published Date : Feb 15, 2010
Study Type : In Vitro Study
Additional Links
Problem Substances : Cipro : CK(47) : AC(8), Fluoroquinolone Antibiotic : CK(82) : AC(11)

Quinolone antibiotics have been reported to cause neurological and psychiatric adverse effects.

Pubmed Data : Drug Saf. 2011 Jun 1;34(6):465-88. PMID: 21585220
Article Published Date : Jun 01, 2011
Study Type : Review
Additional Links
Diseases : Neurologic Disorders : CK(63) : AC(21)
Problem Substances : Cipro : CK(47) : AC(8), Fluoroquinolone Antibiotic : CK(82) : AC(11)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Table eggs may contain residues of fluoroquinolone antibiotics.

Pubmed Data : J Chromatogr A. 2007 Jan 26;1140(1-2):63-70. Epub 2006 Dec 4. PMID: 17147954
Article Published Date : Jan 26, 2007
Study Type : Commentary
Additional Links
Additional Keywords : Environmental Toxicity : CK(6) : AC(4)
Problem Substances : Fluoroquinolone Antibiotic : CK(82) : AC(11)

Related Blogs

What Did The Chicken On Your Plate Eat?
Written by Anne Gordon, RN
Would you eat chicken that eats arsenic and banned antibiotics? You probably already have. When eating that delicious nugget, or scrumptious chicken salad…. do you ever wonder how the tender, juicy, and appealing shades of pink gets to your dinner plate? Welcome factory farming. The human consumption of poultry products is approximately 100 pounds more than any other animal. Each year, factory farms raise about 9 billion broiler chickens.
Fluoroquinolone Antibiotics Linked To Severe Liver Damage
Written by Case Adams, Naturopath
In a nine-year population study, Canadian researchers have determined that at least two fluoroquinolone-based antibiotics – commonly given to patients with respiratory infections, diarrhea, conjunctivitis and other infections — cause acute liver damage.

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