Gluten

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View the Evidence: Problem Substances

Those with aphthous stomatitis may respond favorably to gluten withdrawal.

Pubmed Data : Dig Dis Sci. 1981 Aug ;26(8):737-40. PMID: 7261838
Article Published Date : Aug 01, 1981
Study Type : Human Study
Additional Links
Diseases : Stomatitis: Aphthous : CK(61) : AC(6)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Problem Substances : Gluten : CK(1755) : AC(144)

Unexplained infertility in women may be due to celiac disease.

Pubmed Data : Minerva Med. 2007 Jun;98(3):217-9. PMID: 17592443
Article Published Date : Jun 01, 2007
Study Type : Human Study
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Infertility : CK(455) : AC(94), Infertility: Female : CK(182) : AC(33), Wheat Intolerance : CK(2480) : AC(231)
Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)
Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Unless diagnosis rates improve there will be about 600,000 celiac patients will die in the Mediterranean area in the next 10 years, with an excess of 44.4% vs age- and sex-matched controls.

Pubmed Data : World J Gastroenterol. 2011 Dec 7 ;17(45):4971-8. PMID: 22174546
Article Published Date : Dec 07, 2011
Study Type : Human Study
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215)
Additional Keywords : Celiac Prevalence : CK(121) : AC(13)
Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Wheat gluten may be a pathogenic factor in schizophrenia.

Pubmed Data : Science. 1976 Jan 30;191(4225):401-2. PMID: 1246624
Article Published Date : Jan 30, 1976
Study Type : Human Study
Additional Links
Diseases : Schizophrenia : CK(247) : AC(29)
Problem Substances : Gluten : CK(1755) : AC(144)

Wheat gluten may exert its adverse effects through activation of complement (a cascade of proteins in the blood that form part of innate immunity).

Pubmed Data : Clin Exp Immunol. 1993 Dec;94(3):539-43. PMID: 8252813
Article Published Date : Dec 01, 1993
Study Type : Human Study
Additional Links
Diseases : Acquired hypogammaglobulinemia : CK(81) : AC(8), Celiac Disease : CK(1527) : AC(215), Dermatitis Herpetiformis : CK(41) : AC(5), Hypogammaglobulinemia : CK(10) : AC(1)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)
Problem Substances : Gluten : CK(1755) : AC(144)

Wheat protein antigens likely play a role in a subtype of psoriasis.

Pubmed Data : Br J Dermatol. 2011 Sep 12. Epub 2011 Sep 12. PMID: 21910707
Article Published Date : Sep 12, 2011
Study Type : Human Study
Additional Links
Diseases : Psoriasis : CK(270) : AC(42)
Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Differences in the IgE reactivity of sera towards the two genotypes were quantified by ELISA testing. 39 IgE-binding proteins, some of them unknown until now as wheat allergens were identified.

Pubmed Data : J Proteomics. 2011 Aug 12 ;74(8):1279-89. Epub 2011 Apr 5. PMID: 21473946
Article Published Date : Aug 11, 2011
Study Type : Human In Vitro
Additional Links
Diseases : Food Allergies: Wheat : CK(366) : AC(47)
Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

"Improvement of renal function in epidermolysis bullosa patients after gluten free diet: two cases."

Pubmed Data : Eur Rev Med Pharmacol Sci. 2012 Oct ;16 Suppl 4:138-41. PMID: 23090831
Article Published Date : Sep 30, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Epidermolysis Bullosa : CK(40) : AC(4)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Problem Substances : Gluten : CK(1755) : AC(144)

A case of malabsorption and macroamylasemia reponding positvely to gluten withdrawal has been reported.

Pubmed Data : Am J Med. 1980 Sep ;69(3):451-7. PMID: 6158266
Article Published Date : Sep 01, 1980
Study Type : Human: Case Report
Additional Links
Diseases : Macroamylasemia : CK(19) : AC(1), Malabsorption Syndrome : CK(34) : AC(11)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Problem Substances : Gluten : CK(1755) : AC(144)

A Glutenfree diet improves osteogenesis imperfecta associated with celiac disease and type II diabetes

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Report Med. 2012 ;2012:813461. Epub 2012 Mar 5. PMID: 22481956
Article Published Date : Dec 31, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Diarrhea : CK(544) : AC(72), Osteogenesis Imperfecta : CK(3) : AC(1)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Additional Keywords : Multiple Fractures : CK(3) : AC(1)
Problem Substances : Gluten : CK(1755) : AC(144)

Calcium, Vitamin D and a Gluten-Free diet decreased bone pain and improved muscle strength.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Osteoporos. 2011 Dec ;6(1-2):209-213. Epub 2011 Jun 15. PMID: 22207878
Article Published Date : Dec 01, 2011
Study Type : Human: Case Report
Additional Links
Substances : Calcium : CK(232) : AC(35), Vitamin D : CK(1682) : AC(238)
Diseases : Celiac Disease : CK(1527) : AC(215), Osteomalacia : CK(37) : AC(5), Osteoporosis : CK(1171) : AC(205)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Problem Substances : Gluten : CK(1755) : AC(144)

CD: GFD provides drug free control of seizures and helps correct other features of malabsorption like hypocalcaemia and anaemia

Pubmed Data : J Assoc Physicians India. 2010 Aug ;58:512-5. PMID: 21189704
Article Published Date : Jul 31, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Anemia : CK(89) : AC(12), Celiac Disease : CK(1527) : AC(215), Hypocalcemia : CK(7) : AC(3), Seizures : CK(122) : AC(28)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Additional Keywords : atypical
Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144)

Celiac disease and autoimmune pancreatitis: a case report.

Pubmed Data : Eur J Gastroenterol Hepatol. 2011 Nov ;23(12):1270-2. PMID: 21946127
Article Published Date : Oct 31, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Pancreatitis : CK(164) : AC(40)
Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)
Problem Substances : Gluten : CK(1755) : AC(144)
Adverse Pharmacological Actions : Inflammatory : CK(150) : AC(37)

Celiac disease and migraine disorders may be linked.

Pubmed Data : Headache. 1998 Sep;38(8):627-8. PMID: 11398309
Article Published Date : Sep 01, 1998
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215)
Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Celiac disease with multiple foci of calcification in the spleen has been reported.

Pubmed Data : Indian J Pediatr. 2010 Dec 3. Epub 2010 Dec 3. PMID: 21128017
Article Published Date : Dec 03, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Ectopic Calcification : CK(792) : AC(113), Splenic Calcifications : CK(3) : AC(1), Splenic Diseases : CK(15) : AC(3)
Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Celiac disease, eosinophilic esophagitis, and immediate-type immunoglobulin E-mediated food allergy.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Investig Allergol Clin Immunol. 2011 ;21(1):73-5. PMID: 21370728
Article Published Date : Dec 31, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Eosinophilic esophagitis : CK(66) : AC(5), Food Allergies : CK(420) : AC(57), Food Allergy: Immunoglobulin E-mediated : CK(3) : AC(1), Urticaria : CK(130) : AC(8)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Problem Substances : Gluten : CK(1755) : AC(144)

Epilepsy with cerebral calcifications poorly responsive to antiepileptic treatment have been reported significantly improved with folic acid and a gluten-free diet.

Pubmed Data : Acta Paediatr Scand. 1991 May;80(5):559-62. PMID: 1908173
Article Published Date : May 01, 1991
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Cerebral Calcifications : CK(13) : AC(2), Epilepsy : CK(128) : AC(27), Epilepsy: With Cerebral Calcifications : CK(24) : AC(3), Folic Acid/Folate Deficiency : CK(13) : AC(2)
Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)
Problem Substances : Gluten : CK(1755) : AC(144)

Gluten encephalopathy with psychiatric onset has been reported.

Pubmed Data : Clin Pract Epidemiol Ment Health. 2009;5:16. Epub 2009 Jun 26. PMID: 19558661
Article Published Date : Jan 01, 2009
Study Type : Human: Case Report
Additional Links
Diseases : Encephalopathies : CK(11) : AC(5), Gluten Intolerance : CK(236) : AC(33), Polyneuropathies : CK(38) : AC(7)
Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Gluten sensitivity presenting as neuromyelitis optica has been reported.

Pubmed Data : J Neurol Neurosurg Psychiatry. 2005 Jul ;76(7):1028-30. PMID: 15965221
Article Published Date : Jul 01, 2005
Study Type : Human: Case Report
Additional Links
Diseases : Gluten Sensitivity : CK(2477) : AC(270), Neuromyelitis Optica : CK(4) : AC(2)
Problem Substances : Gluten : CK(1755) : AC(144)

Gluten-free diet effective in celiac disease related uveitis

Pubmed Data : Rheumatol Int. 2011 Mar ;31(3):399-402. Epub 2009 Oct 14. PMID: 19826819
Article Published Date : Feb 28, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Uveitis : CK(63) : AC(10)
Additional Keywords : Mucosal inflammation
Problem Substances : Gluten : CK(1755) : AC(144)

Gluten-related recurrent peripheral facial palsy.

Pubmed Data : J Neurol Neurosurg Psychiatry. 2012 Mar 1. Epub 2012 Mar 1. PMID: 22383733
Article Published Date : Mar 01, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Facial Palsy : CK(3) : AC(1)
Problem Substances : Gluten : CK(1755) : AC(144)

IgA, intestinal biopsy point to link between cold urticaria and celiac disease in high-risk HLA types

Pubmed Data : J Investig Allergol Clin Immunol. 2008 ;18(2):123-5. PMID: 18447142
Article Published Date : Dec 31, 2007
Study Type : Human: Case Report
Additional Links
Substances : Dietary Modification: Wheat/Gluten Free : CK(3) : AC(1)
Diseases : Asthma : CK(918) : AC(134), Celiac Disease : CK(1527) : AC(215), Urticaria : CK(130) : AC(8)
Additional Keywords : Genetic Pre-disposition : CK(3) : AC(1), Gluten Intolerance : CK(3) : AC(1), Legume Intolerance : CK(3) : AC(1), Pollen Sensitivity : CK(3) : AC(1)
Problem Substances : Gluten : CK(1755) : AC(144)

Macroamylasemia attributable to gluten-related amylase autoantibodies has been reported.

Pubmed Data : Pediatrics. 2001 Jun ;107(6):E93. PMID: 11389291
Article Published Date : Jun 01, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Macroamylasemia : CK(19) : AC(1)
Problem Substances : Gluten : CK(1755) : AC(144)

Progressive ataxia with palatal tremor due to gluten sensitivity has been reported.

Pubmed Data : Mov Disord. 2012 Jan ;27(1):62-3. PMID: 22252893
Article Published Date : Jan 01, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Ataxia : CK(96) : AC(14), Tremor : CK(39) : AC(8)
Problem Substances : Gluten : CK(1755) : AC(144)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Regression of conjunctival tumor in celiac disease patient attributed to glutenfree diet.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Ophthalmol. 2010 Sep-Oct;58(5):433-4. PMID: 20689203
Article Published Date : Aug 31, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease : CK(1527) : AC(215), Conjunctival Tumor : CK(3) : AC(1)
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free : CK(259) : AC(29)
Additional Keywords : Breast feeding, Food Intolerance, Ophthalmology, Tumor
Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144)

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