Hormone Replacement Therapy

Hormone Replacement Therapy

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Article Count - 6
Cumulative Knowledge - 81

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Quick Summary: Current access displays 2 out of 4 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Breast Cancer	50	3	Log in \| Sign up
Breast Cancer: Prevention	40	2	Log in \| Sign up

Quick Summary: 2 associated Adverse Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Carcinogenic	40	2	Log in \| Sign up
Neurotoxic	1	1	Log in \| Sign up

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View the Evidence: Problem Substances

Hormone replacement therapy is associated with an increased risk of breast cancer of women in Korea.

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Pubmed Data : Asia Pac J Public Health. 2011 Jan 25. Epub 2011 Jan 25. PMID: 21266394

Article Published Date : Jan 25, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Breast Cancer : CK(2361) : AC(621), Breast Cancer: Prevention : CK(525) : AC(73)

Problem Substances : Hormone Replacement Therapy : CK(81) : AC(6)

Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Hormone replacement therapy is associated with an increased risk of invasive breast cancer.

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Pubmed Data : PLoS One. 2011 ;6(10):e25183. Epub 2011 Oct 6. PMID: 21998640

Article Published Date : Jan 01, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Breast Cancer : CK(2361) : AC(621), Breast Cancer: Invasive Lobular Carcinoma (ILC) : CK(51) : AC(4), Breast Cancer: Prevention : CK(525) : AC(73)

Problem Substances : Hormone Replacement Therapy : CK(81) : AC(6)

Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Estrogen plus progestin increases breast cancer risk in postmenopausal women.

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Pubmed Data : N Engl J Med. 2009 Feb 5;360(6):573-87. PMID: 19196674

Article Published Date : Feb 05, 2009

Study Type : Human Study

Additional Links

Diseases : Breast Cancer : CK(2361) : AC(621)

Problem Substances : 17beta-estradiol : CK(38) : AC(7), Hormone Replacement Therapy : CK(81) : AC(6), Progestin : CK(33) : AC(5)

Estrogen-progestin and estrogen hormone replacement therapy increase mammographic density.

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Pubmed Data : J Reprod Med. 2007 Jun;52(6):513-20. PMID: 17694969

Article Published Date : Jun 01, 2007

Study Type : Human Study

Additional Links

Problem Substances : Estrogen-Progestin : CK(10) : AC(1), Hormone Replacement Therapy : CK(81) : AC(6)

Hormonal contraceptives and hormone replacement therapy is associated with 2- to 6- fold increased relative risk of venous thromboembolic events.

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Pubmed Data : Arch Intern Med. 2004 Oct 11;164(18):1965-76. PMID: 15477430

Article Published Date : Oct 11, 2004

Study Type : Human Study

Additional Links

Problem Substances : Ethinyl Estradiol plus Lynestrenol : CK(34) : AC(5), Hormone Replacement Therapy : CK(81) : AC(6), Levonorgestrel/ethinyl estradiol : CK(41) : AC(5), Oral Contraceptives : CK(287) : AC(24), Progestin : CK(33) : AC(5)

Tibolone increases bone mineral density but also relapse in breast cancer survivors. This increase in breast cancer was not seen in those women with low BMD.

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Pubmed Data : Breast Cancer Res. 2012 Jan 17 ;14(1):R13. Epub 2012 Jan 17. PMID: 22251615

Article Published Date : Jan 17, 2012

Study Type : Human Study

Additional Links

Diseases : Breast Cancer : CK(2361) : AC(621)

Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Problem Substances : Hormone Replacement Therapy : CK(81) : AC(6), Hormone Replacement Therapy: Tibolone : CK(10) : AC(1)

Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Hormone therapy in postmenopausal women increase the risk of stroke.

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Pubmed Data : Womens Health (Lond Engl). 2011 May ;7(3):355-61. PMID: 21612355

Article Published Date : May 01, 2011

Study Type : Review

Additional Links

Diseases : Stroke : CK(540) : AC(47)

Problem Substances : Hormone Replacement Therapy : CK(81) : AC(6)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

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