Lovastatin

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73 Diseases Researched for Lovastatin
NameACCKFocus
Statin-Induced Pathologies46181Locked
High Cholesterol450Locked
Chemically-Induced Liver Damage634Locked
Myopathies524Locked
Drug-Induced Nutrient Depletion: Statin Drugs322Locked
Drug-Induced Toxicity 321Locked
Cancers: All120Locked
Coronary Artery Disease220Locked
Creatine Phosphokinase (CK): Elevated213Locked
Sleep Disorders213Locked
Cholesterol: Oxidation212Locked
Coenzyme Q10 Deficiency212Locked
Rhabdomyolysis412Locked
Cognitive Decline/Dysfunction211Locked
Mitochondrial Myopathies211Locked
Aldosterone levels: Low110Locked
Athletic Performance110Locked
Hormonal Perturbations: Dopamine Elevation110Locked
Hormonal Perturbations: Homovanillic acid (HVA) Elevations110Locked
Insomnia110Locked
Memory Disorders110Locked
Muscle Damage: Exercise-Induced110Locked
Muscle Soreness: Exercise-Induced110Locked
Muscle Stiffness: Exercise-Induced110Locked
Neuropsychological Dysfunction: Psychomotor Speed110Locked
Neurotoxicity610Locked
Oxidative Stress110Locked
Polyneuropathies110Locked
Psychological Well-Being110Locked
Birth Defects28Locked
Hepatitis26Locked
Hepatitis: Cholestatic26Locked
Peripheral Neuropathies26Locked
Prenatal Chemical Exposures26Locked
Abortion: Spontaneous15Locked
Heart Failure45Locked
Appetite Disorders: Loss/Lack of 13Locked
Brain Damage23Locked
Cholestasis13Locked
GGT13Locked
Hyperkalemia13Locked
Hyperthermia13Locked
Kidney Damage: Drug-Induced13Locked
Kidney Failure: Acute13Locked
Kidney Failure: Chronic13Locked
Lens Diseases23Locked
Lichenoid Dermatitis13Locked
Lipid Peroxidation13Locked
Mitochondrial Dysfunction 23Locked
Pancreatitis13Locked
Pregnancy: Environmental Exposures13Locked
Smell Disorders13Locked
Blood-Brain-Barrier Disorders12Locked
Death: Statin-Induced12Locked
Demyelinating Diseases22Locked
Eye Diseases12Locked
Immune Dysregulation: TH1/TH2 imbalance12Locked
Lens Damage12Locked
Liver Damage12Locked
Lung Diseases12Locked
Neurodegenerative Diseases12Locked
Skin Problems: Compromised Barrier Function12Locked
Thyroid Cancer12Locked
Aging11Locked
Cataract11Locked
Immune Disorders: Low Immune Function11Locked
Influenza A11Locked
Lens Opacities11Locked
Low Testosterone11Locked
Myasthenia Gravis11Locked
Neurologic Disorders11Locked
Ovarian Diseases11Locked
Ovulation Disorders11Locked
16 Adverse Pharmacological Actions Researched for Lovastatin

View the Evidence:
68 Abstracts with Lovastatin Research

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Pubmed Data : J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID: 17662392
Study Type : Meta Analysis
Additional Links
Adverse Pharmacological Actions : Carcinogenic
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Pubmed Data : J Clin Pharm Ther. 2004 Feb ;29(1):71-3. PMID: 14748901
Study Type : Human Study
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Pubmed Data : Neurology. 2002 May 14 ;58(9):1333-7. PMID: 12011277
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Proc Natl Acad Sci U S A. 1990 Nov;87(22):8931-4. PMID: 2247468
Study Type : Human Study
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Pubmed Data : FEBS Lett. 1997 Jun 30;410(2-3):254-8. PMID: 9237640
Study Type : Human Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Oxidant
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Pubmed Data : Clin Pharmacol Ther. 1991 Dec ;50(6):730-7. PMID: 1752118
Study Type : Human Study
Additional Links
Problem Substances : Lovastatin
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Pubmed Data : Metabolism. 1997 Oct ;46(10):1206-10. PMID: 9322808
Study Type : Human Study
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Pubmed Data : Am J Med. 2000 May ;108(7):538-46. PMID: 10806282
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Toxicol Mech Methods. 2009 Jan;19(1):44-50. PMID: 19778232
Study Type : Human Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
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Pubmed Data : J Clin Pharmacol. 1993 Mar;33(3):226-9. PMID: 8463436
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Cytotoxic
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Pubmed Data : Pharmacotherapy. 2003 Jul ;23(7):871-80. PMID: 12885101
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Drug Saf. 2002 ;25(12):877-83. PMID: 12241128
Study Type : Human Study
Additional Links
Diseases : Oxidative Stress
Adverse Pharmacological Actions : Oxidant
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Pubmed Data : Clin Ther. 1990 Sep-Oct;12(5):410-20. PMID: 2268863
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor
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Pubmed Data : Endocrine. 2009 Feb;35(1):38-46. Epub 2008 Dec 3. PMID: 19051066
Study Type : Human Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Mol Aspects Med. 1997 ;18 Suppl:S137-44. PMID: 9266515
Study Type : Human Study
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Pubmed Data : Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID: 7708017
Study Type : Human In Vitro
Additional Links
Pharmacological Actions : Antiproliferative
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic, Teratogenic
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Pubmed Data : Gastroenterol Clin Biol. 1991 ;15(1):94-5. PMID: 2010080
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Dig Dis Sci. 1994 Sep ;39(9):2032-3. PMID: 8082513
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Hepatotoxic
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Engl J Med. 2005 Jun 30 ;352(26):2759. PMID: 15987932
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Teratogenic
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Pubmed Data : Gastroenterol Hepatol. 1998 Mar ;21(3):127-8. PMID: 9607293
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : N Engl J Med. 1989 May 4 ;320(18):1219-20. PMID: 2710198
Study Type : Human: Case Report
Additional Links
Diseases : Hyperkalemia
Problem Substances : Lovastatin
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Pubmed Data : Atherosclerosis. 2000 Nov ;153(1):255-6. PMID: 11058722
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Oxidant
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Pubmed Data : Acta Derm Venereol. 2004 ;84(3):229-30. PMID: 15202842
Study Type : Human: Case Report
Additional Links
Problem Substances : Fluvastatin, Lovastatin
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Pubmed Data : Jpn Heart J. 1997 Jul ;38(4):541-5. PMID: 9350151
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Nephrotoxic
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Pubmed Data : Dtsch Med Wochenschr. 1995 Feb 24 ;120(8):252-6. PMID: 7867482
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Postgrad Med J. 1990 Apr ;66(774):294-6. PMID: 2385552
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
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Pubmed Data : CMAJ. 1993 Feb 1 ;148(3):374. PMID: 8439902
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Laryngorhinootologie. 1992 Sep ;71(9):483-4. PMID: 1388478
Study Type : Human: Case Report
Additional Links
Diseases : Smell Disorders
Problem Substances : Lovastatin
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Pubmed Data : J Neurol Neurosurg Psychiatry. 1995 May ;58(5):625-8. PMID: 7745415
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : South Med J. 1998 Jul ;91(7):667-8. PMID: 9671841
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Adverse Pharmacological Actions : Neurotoxic
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : West J Med. 1994 Oct ;161(4):427-8. PMID: 7817565
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
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Pubmed Data : Clin Chem. 1990 Dec ;36(12):2145-7. PMID: 2253372
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Lancet. 1994 Apr 16 ;343(8903):973. PMID: 7909021
Study Type : Human: Case Report
Additional Links
Problem Substances : Lovastatin
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JOP. 2004 Nov ;5(6):502-4. Epub 2004 Nov 10. PMID: 15536291
Study Type : Human: Case Report
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Pubmed Data : Wien Klin Wochenschr. 1996 ;108(11):334-7. PMID: 8767987
Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Nephrotoxic
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Pubmed Data : Life Sci. 1999 ;64(23):2155-61. PMID: 10372657
Study Type : Animal Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Exp Eye Res. 1991 Aug ;53(2):179-86. PMID: 1915674
Study Type : Animal Study
Additional Links
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Pubmed Data : Neurosci Lett. 2002 Nov 29 ;333(3):167-70. PMID: 12429374
Study Type : Animal Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Immunoreactive
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Pubmed Data : Biochim Biophys Acta. 1994 Jul 6 ;1200(2):100-8. PMID: 8031828
Study Type : Animal Study
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Pubmed Data : J Neuropathol Exp Neurol. 1993 Sep ;52(5):542-9. PMID: 8360706
Study Type : Animal Study
Additional Links
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Pharm Res. 1994 Feb ;11(2):305-11. PMID: 8165193
Study Type : Animal Study
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Am J Physiol. 1997 Jan ;272(1 Pt 1):L106-14. PMID: 9038909
Study Type : Animal Study
Additional Links
Diseases : Lung Diseases
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin
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Pubmed Data : Eur Rev Med Pharmacol Sci. 2011 Sep ;15(9):985-91. PMID: 22013720
Study Type : Animal Study
Additional Links
Pharmacological Actions : Antiproliferative
Problem Substances : Atorvastatin, Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Eur J Pharmacol. 1994 Aug 3 ;270(4):365-9. PMID: 7805787
Study Type : Animal Study
Additional Links
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : J Clin Invest. 1990 Nov ;86(5):1738-45. PMID: 2243142
Study Type : Animal Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
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Pubmed Data : Toxicol Pathol. 1991 ;19(3):197-205. PMID: 1780636
Study Type : Animal Study
Additional Links
Diseases : Thyroid Cancer
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Pubmed Data : Arterioscler Thromb Vasc Biol. 1999 Jun;19(6):1541-8. PMID: 10364087
Study Type : Animal Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
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Pubmed Data : J Submicrosc Cytol Pathol. 1995 Oct ;27(4):435-44. PMID: 7585443
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Enzyme Inhibitors
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Mol Cell Neurosci. 2001 Feb ;17(2):329-41. PMID: 11178870
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : J Neurochem. 1999 Jun ;72(6):2278-85. PMID: 10349836
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Glia. 2009 Mar;57(4):402-13. PMID: 18814266
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin
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Pubmed Data : Exp Clin Endocrinol. 1990 Sep ;96(1):15-24. PMID: 2279522
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Endocrine Disruptor
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Pubmed Data : J Neurochem. 1994 Apr ;62(4):1539-45. PMID: 8133281
Study Type : In Vitro Study
Additional Links
Additional Keywords : Remyelination
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Toxicol Appl Pharmacol. 2003 Dec 15 ;193(3):346-55. PMID: 14678744
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Apoptotic
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic
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Pubmed Data : Neurobiol Aging. 2010 Sep ;31(9):1543-53. Epub 2008 Oct 31. PMID: 18951667
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents, Apoptotic
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Toxicology. 2006 Feb 15 ;219(1-3):124-32. Epub 2005 Dec 15. PMID: 16343726
Study Type : Review
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cytotoxic
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Pubmed Data : Biol Reprod. 2005 Mar ;72(3):538-45. Epub 2004 Sep 22. PMID: 15385411
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Apoptotic, Endocrine Disruptor: Ovary
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Pubmed Data : Toxicol Appl Pharmacol. 1995 Mar ;131(1):163-74. PMID: 7878672
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Exp Eye Res. 1990 Jan ;50(1):65-78. PMID: 2307197
Study Type : Review
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cataractogenic
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Pubmed Data : J Neurochem. 2011 Sep 7. Epub 2011 Sep 7. PMID: 21899539
Study Type : Review
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Am J Physiol. 1991 Nov ;261(5 Pt 1):C780-6. PMID: 1659206
Study Type : In Vitro Study
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Pubmed Data : Cell Immunol. 2010 ;264(1):71-7. Epub 2010 May 4. PMID: 20483407
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Immunosuppressive
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Pubmed Data : Neurology. 2004 Dec 14 ;63(11):2188. PMID: 15596782
Study Type : Review
Additional Links
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Pubmed Data : Cardiovasc Toxicol. 2007 ;7(1):1-9. PMID: 17646677
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Apoptotic
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic
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Pubmed Data : J Neurochem. 1986 Apr ;46(4):1283-91. PMID: 3633306
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Toxicol Appl Pharmacol. 1997 Jul ;145(1):99-110. PMID: 9221829
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin, Pravastatin , Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Pharmacology. 2008 ;82(1):74-82. Epub 2008 May 27. PMID: 18504415
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic
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Pubmed Data : Reprod Toxicol. 2010 Aug;30(1):121-30. Epub 2010 May 20. PMID: 20493250
Study Type : In Vitro Study
Additional Links
Problem Substances : Lovastatin, Warfarin
Adverse Pharmacological Actions : Embryotoxic, Teratogenic

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There is a little known natural extract of plant waxes known as policosanol, extractable from sugar cane, yams, and beeswax, which has been giving some of the more profitable drugs on the market a biomedical beating since it was first investigated in clinical trials by the Cubans in the 1990's.
Written by Sayer Ji, Founder
There is a little known natural extract of plant waxes known as policosanol, extractable from sugar cane, yams, and beeswax, which has been giving some of the more profitable drugs on the market a biomedical beating since it was first investigated in clinical trials by the Cubans in the 1990's.
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Research revealing the broad spectrum toxicity of statin drugs continues to accumulate unabated. Adding to a growing body of clinical evidence that they may cause over 300 adverse health effects, a new study reveals that these cholesterol-lowering drugs may be contributing to an epidemic of arthritis and autoimmunity in exposed populations, as well.
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In a 2008 study published in the journal Food Chemistry & Toxicology titled, "Comparative evaluation of the hypolipidemic effects of coconut water and lovastatin in rats fed fat-cholesterol enriched diet," the beverage coconut water was as effective as Merck's original cholesterol-lowering drug in positively modulating blood lipid levels in rats.
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Written by Justin Smith
An estimated 40 million people take a statin to lower their cholesterol levels. These are one of the most widely prescribed medications in history and, of course, one of the most profitable.

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