Monosodium Glutamate (MSG)

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Quick Summary: Current access displays 2 out of 19 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Obesity	14	7	Log in \| Sign up
Amyotrophic Lateral Sclerosis	10	1	Log in \| Sign up

Quick Summary: Current access displays 2 out of 5 associated Adverse Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Excitotoxic	10	1	Log in \| Sign up
Endocrine Disruptor	6	3	Log in \| Sign up

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View the Evidence: Problem Substances

Glutamate levels may contribute to the pathogenesis of ALS.

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Pubmed Data : Acta Neurol Scand. 2010 Feb;121(2):120-6. Epub 2009 Oct 5. PMID: 19804473

Article Published Date : Feb 01, 2010

Study Type : Human Study

Additional Links

Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68)

Problem Substances : L-glutamic Acid : CK(11) : AC(2), Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Excitotoxic : CK(10) : AC(1)

The elimination of MSG, Aspartame and other excitotoxins from the diets of patients with fibromyalgia is a successful treatment option.

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Pubmed Data : Ann Pharmacother. 2001 Jun;35(6):702-6. PMID: 11408989

Article Published Date : Jun 01, 2001

Study Type : Human Study

Additional Links

Diseases : Excitotoxicity : CK(52) : AC(30), Fibromyalgia : CK(507) : AC(55)

Problem Substances : Aspartame : CK(77) : AC(27), Monosodium Glutamate (MSG) : CK(39) : AC(12)

"Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome."

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Pubmed Data : Dig Liver Dis. 2012 Mar 21. Epub 2012 Mar 21. PMID: 22444524

Article Published Date : Mar 21, 2012

Study Type : Animal Study

Additional Links

Substances : Spirulina : CK(77) : AC(20)

Diseases : Dyslipidemias : CK(172) : AC(31), Leptin: Elevated Levels : CK(15) : AC(9), Metabolic Syndrome X : CK(581) : AC(110), Nonalcoholic fatty liver disease (NAFLD) : CK(50) : AC(16)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Dietary monosodium glutamate increases weight gain and adiposity, and reduces insulin sensitivity in an animal model.

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Pubmed Data : Br J Nutr. 2011 Mar 24:1-10. Epub 2011 Mar 24. PMID: 21429276

Article Published Date : Mar 24, 2011

Study Type : Animal Study

Additional Links

Diseases : Abdominal Obesity (Midsection Fat) : CK(328) : AC(53), Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Insulin Resistance : CK(995) : AC(212), Obesity : CK(1726) : AC(264), Overweight : CK(2077) : AC(332)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Obesogenic : CK(49) : AC(9)

High Fructose Corn Syrup may promote hepatic steatosis, whereas dietary Monosodium Glutamate (MSG) induces dyslipidemia and markers of insulin resistance.

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Pubmed Data : Obesity (Silver Spring). 2010 Jan 28. Epub 2010 Jan 28. PMID: 20111022

Article Published Date : Jan 28, 2010

Study Type : Animal Study

Additional Links

Diseases : Dyslipidemias : CK(172) : AC(31), Fatty Liver : CK(490) : AC(118), Insulin Resistance : CK(995) : AC(212)

Problem Substances : High Fructose Corn Syrup : CK(67) : AC(10), Monosodium Glutamate (MSG) : CK(39) : AC(12)

Monosodium glutamate induces fatty liver, insulin and triglyceride elevations, increased weight gain and adverse liver changes.

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Pubmed Data : J Lipid Res. 2009 Aug;50(8):1521-37. Epub 2008 Nov 11. PMID: 19001666

Article Published Date : Aug 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Fatty Liver : CK(490) : AC(118), Hyperinsulinism : CK(1175) : AC(41), Liver Damage : CK(597) : AC(213), Triglycerides: Elevated : CK(366) : AC(65), Weight Problems : CK(2077) : AC(334)

Problem Substances : Insulin : CK(67) : AC(9), Monosodium Glutamate (MSG) : CK(39) : AC(12), Trans Fatty Acids : CK(281) : AC(39)

Monosodium glutamate is used to induce hypothalamic obesity in a female rat model.

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Pubmed Data : J Pediatr Endocrinol Metab. 2011;24(3-4):131-7. PMID: 21648279

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Obesity : CK(1726) : AC(264), Obesity: Hypothalamic : CK(2) : AC(1)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Neurotoxic : CK(1042) : AC(170)

Monosodium glutamate is used to induce insulin resistance and obesity in an animal model.

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Pubmed Data : Lipids Health Dis. 2011;10:66. Epub 2011 Apr 28. PMID: 21526994

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Insulin Resistance : CK(995) : AC(212), Obesity : CK(1726) : AC(264)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Endocrine Disruptor : CK(461) : AC(76)

Monosodium glutamate is used to induce metabolic syndrome in a rat model.

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Pubmed Data : Eur J Pharmacol. 2011 Jul 15;662(1-3):1-8. Epub 2011 May 1. PMID: 21549692

Article Published Date : Jul 15, 2011

Study Type : Animal Study

Additional Links

Diseases : Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Hyperlipidemia : CK(1212) : AC(109), Metabolic Syndrome X : CK(581) : AC(110), Obesity : CK(1726) : AC(264)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Endocrine Disruptor : CK(461) : AC(76)

Monosodium glutamate is used to induce obesity and fatty liver in an animal model.

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Pubmed Data : Metabolism. 2011 Apr 11. Epub 2011 Apr 11. PMID: 21489575

Article Published Date : Apr 11, 2011

Study Type : Animal Study

Additional Links

Diseases : Fatty Liver : CK(490) : AC(118), Obesity : CK(1726) : AC(264)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Obesogenic : CK(49) : AC(9)

MSG increases Obesity gene expression, leptin, insulin, LDL cholesterol, total lipids (TL), glucose and decreased leptin receptor-b gene expression.

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Pubmed Data : Acta Physiol Hung. 2011 Jun ;98(2):177-88. PMID: 21616776

Article Published Date : Jun 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Obesity : CK(1726) : AC(264), Overweight : CK(2077) : AC(332)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Endocrine disruption: Leptin resistance : CK(6) : AC(3), Endocrine Disruptor : CK(461) : AC(76)

Neonatal monosodium glutamate intoxication is associated with obesity in the adult stage.

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2011 Jun;108(6):406-13. Epub 2011 Feb 9. PMID: 21205225

Article Published Date : Jun 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Infant Nutrition : CK(72) : AC(14), Obesity : CK(1726) : AC(264)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Obesogenic : CK(49) : AC(9)

Monosodium glutamate may contribute to neurological problems by affecting the gut-brain axis.

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Pubmed Data : Digestion. 2011;83 Suppl 1:37-43. Epub 2011 Mar 10. PMID: 21389727

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Diseases : Gut Brain Axis: Imabalance : CK(20) : AC(8)

Problem Substances : Monosodium Glutamate (MSG) : CK(39) : AC(12)

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