Pepper Spray

Pepper Spray

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Quick Summary: Current access displays 2 out of 14 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Cornea Damage	40	3	Log in \| Sign up
Corneal Erosion	20	1	Log in \| Sign up

Quick Summary: 2 associated Adverse Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Cytotoxic	10	1	Log in \| Sign up
Neurotoxic	10	1	Log in \| Sign up

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View the Evidence: Problem Substances

"Toxic carriers in pepper sprays may cause corneal erosion."

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Pubmed Data : Toxicol Appl Pharmacol. 2003 Feb 1 ;186(3):155-62. PMID: 12620368

Article Published Date : Feb 01, 2003

Study Type : Meta Analysis

Additional Links

Diseases : Cornea Damage : CK(60) : AC(5), Corneal Erosion : CK(20) : AC(1)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

"Pepper spray application to the eye might result in severe and permanent damage to the corneo-conjunctival tissue which is not adequately addressed in the current literature."

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Pubmed Data : Klin Monbl Augenheilkd. 2005 Mar ;222(3):267-70. PMID: 15785998

Article Published Date : Mar 01, 2005

Study Type : Human Study

Additional Links

Diseases : Conjunctival Damage : CK(10) : AC(1), Cornea Damage : CK(60) : AC(5), Eye Damage : CK(20) : AC(2)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Benzyl Alcohol : CK(10) : AC(1), Pepper Spray : CK(85) : AC(11)

Pepper spray has been reported to cause significant eye damage.

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Pubmed Data : Int Ophthalmol. 2005 Aug-Oct;26(4-5):171-3. Epub 2007 Jan 26. PMID: 17253111

Article Published Date : Aug 01, 2005

Study Type : Human Study

Additional Links

Diseases : Eye Damage : CK(20) : AC(2)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Pepper spray may result in damage to corneal nerve terminals with physical symptoms that last at least a week.

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Pubmed Data : Invest Ophthalmol Vis Sci. 2000 Jul ;41(8):2138-47. PMID: 10892855

Article Published Date : Jul 01, 2000

Study Type : Human Study

Additional Links

Diseases : Cornea Damage : CK(60) : AC(5)

Pharmacological Actions : Neuritogenic : CK(94) : AC(43)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Adverse Pharmacological Actions : Cytotoxic : CK(64) : AC(35), Neurotoxic : CK(1042) : AC(170)

Pepper spray-induced corneal abrasions are not rare events;of 100 cases of pepper spray exposure identified, seven patients had sustained corneal abrasions.

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Pubmed Data : Am J Emerg Med. 2000 May ;18(3):271-2. PMID: 10830682

Article Published Date : May 01, 2000

Study Type : Human Study

Additional Links

Diseases : Corneal Abrasions : CK(10) : AC(1)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Pepper spraying human subjects results in punctate epithelial erosions in their cornea.

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Pubmed Data : Ophthalmology. 2000 Dec ;107(12):2186-9. PMID: 11097593

Article Published Date : Dec 01, 2000

Study Type : Human Study

Additional Links

Diseases : Corneal Damage: punctate epithelial erosion : CK(10) : AC(1)

Pharmacological Actions : Analgesics : CK(374) : AC(76)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Corneal ulcer associated with pepper spray exposure during military training has been reported.

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Pubmed Data : J Emerg Med. 2011 Nov 17. Epub 2011 Nov 17. PMID: 22100497

Article Published Date : Nov 17, 2011

Study Type : Human: Case Report

Additional Links

Diseases : Corneal Ulcer : CK(3) : AC(1)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Pepper spray induced conjunctival proliferation, serious enough to require surgical excision, has been reported.

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Pubmed Data : Cornea. 2011 Sep ;30(9):1042-4. PMID: 21642850

Article Published Date : Sep 01, 2011

Study Type : Human: Case Report

Additional Links

Diseases : Conjunctival Diseases : CK(15) : AC(5)

Pharmacological Actions : Antiproliferative : CK(969) : AC(725)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Pepper spray may contribute to "in-custody deaths."

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Pubmed Data : Am J Forensic Med Pathol. 1995 Sep ;16(3):185-92. PMID: 7495257

Article Published Date : Sep 01, 1995

Study Type : Human: Case Report

Additional Links

Diseases : In-Custody Death : CK(3) : AC(1), Myocardial Infarction : CK(2598) : AC(117)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Pepper-spray-induced respiratory failure has been reported.

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Pubmed Data : Pediatrics. 1996 Nov ;98(5):961-3. PMID: 8909494

Article Published Date : Nov 01, 1996

Study Type : Human: Case Report

Additional Links

Diseases : Respiratory Failure: Chemically-Induced : CK(3) : AC(1)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Sudden death caused by an oleoresin capsicum spray [pepper spray] has been reported.

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Pubmed Data : Arch Med Sadowej Kryminol. 2009 Jul-Sep;59(3):252-4. PMID: 20441089

Article Published Date : Jul 01, 2009

Study Type : Human: Case Report

Additional Links

Diseases : Asphyxia : CK(3) : AC(1), Laryngeal Edema : CK(3) : AC(1), Sudden Death : CK(6) : AC(2)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

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