Perchlorate

Perchlorate is an environmental pollutant primarily associated with releases by defense contractors, military operations and aerospace programs, as it is a key ingredient in rocket fuel. It is now found in virtually all humans tested, and it is continually making its way up the food chain through ground and drinking water, into feed and edible plants, animals products, milk and breast milk - contaminating conventional and organically grown food, alike.

What does it do? Perchlorate has been used as a "medicine" in this country to "treat" hyperthyroidism since the 1950's despite the fact some patients may develop aplastic anemia (bone marrow destruction) as a result. Perchlorate interferes with iodide uptake at the sodium-iodide symporter in the thyroid gland which unfortunately has a 30-fold higher affinity for perchlorate than iodide. Without adequate iodide hypothyroidism ensues. Could this pollutant have anything to do with the geometric expansion of hypothyroidism diagnoses in this country?

If it were not for the perfect fit between pharmaceutical medicine, e.g. Synthroid (levothyroxine) and pollution-caused hypothyroidism, this question might get some traction in the medical community and we could start solving the underlying problem: a military-industrial establishment and medical-industrial establishment that thrive on death and disease.

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Quick Summary: Current access displays 2 out of 15 associated Diseases
NameCumulative KnowledgeArticle CountFocus Articles
Perchlorate Toxicity 437Log in | Sign up
Hypothyroidism266Log in | Sign up
View the Evidence: Problem Substances
Pubmed Data : J Expo Sci Environ Epidemiol. 2009 Mar 18. Epub 2009 Mar 18. PMID: 19293845
Study Type : Human Study

Pubmed Data : Environ Sci Technol. 2008 Nov 1 ;42(21):8115-21. PMID: 19031911
Study Type : Human Study

Pubmed Data : PLoS One. 2011;6(3):e17015. Epub 2011 Mar 4. PMID: 21394205
Study Type : Human Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Bioaccumulator : CK(102) : AC(23)

Pubmed Data : Thyroid. 2000 Aug;10(8):659-63. PMID: 11014310
Study Type : Human Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(461) : AC(76)

Pubmed Data : Environ Health Perspect. 2002 Sep;110(9):927-37. PMID: 12204829
Study Type : Human Study

Pubmed Data : Environ Sci Pollut Res Int. 2002;9(3):187-92. PMID: 12094532
Study Type : Human Study

Pubmed Data : Environ Sci Technol. 2005 Apr 1;39(7):2011-7. PMID: 15871231
Study Type : Human Study

Pubmed Data : Environ Health Perspect. 2008 Jun;116(6):752-60. PMID: 18560531
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Teratogenic : CK(317) : AC(59)

Pubmed Data : Environ Toxicol Chem. 2002 Mar;21(3):590-7. PMID: 11878472
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)

Pubmed Data : Lab Anim. 2011 Jul;45(3):209-14. Epub 2011 Jun 13. PMID: 21669905
Study Type : Animal Study

Pubmed Data : Toxicol Ind Health. 2010 Oct 12. Epub 2010 Oct 12. PMID: 20937628
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Inflammatory : CK(135) : AC(37)

Pubmed Data : Arch Environ Contam Toxicol. 2009 Oct;57(3):598-607. Epub 2009 Mar 24. PMID: 19308637
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(461) : AC(76)

Pubmed Data : J Agric Food Chem. 2008 Jul 9;56(13):5443-50. Epub 2008 Jun 13. PMID: 18553887
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Bioaccumulator : CK(102) : AC(23)

Pubmed Data : Environ Toxicol Chem. 2006 Aug;25(8):2087-96. PMID: 16916028
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)

Pubmed Data : Toxicol Lett. 2009 Mar 28;185(3):160-7. Epub 2008 Dec 30. PMID: 19152830
Study Type : Animal Study

Pubmed Data : Toxicol Sci. 2007 Apr;96(2):246-54. Epub 2007 Jan 6. PMID: 17205975
Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(461) : AC(76)

Pubmed Data : Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):801-13. PMID: 19942155
Study Type : Commentary

Pubmed Data : J Agric Food Chem. 2005 Jan 26;53(2):369-73. PMID: 15656674
Study Type : In Vitro Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Bioaccumulator : CK(102) : AC(23)

Pubmed Data : Anal Chim Acta. 2006 May 10;567(1):26-32. Epub 2006 Mar 16. PMID: 17723375
Study Type : Review

Pubmed Data : Shokuhin Eiseigaku Zasshi. 2009 Aug;50(4):184-9. PMID: 19745587
Study Type : Review
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)

Pubmed Data : Environ Sci Technol. 2007 Jan 1;41(1):88-92. PMID: 17265931
Study Type : Review
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)

Pubmed Data : Environ Int. 2007 Oct;33(7):955-62. Epub 2007 Jul 2. PMID: 17604836
Study Type : Review
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)

Pubmed Data : J Agric Food Chem. 2009 Oct 14;57(19):9250-5. PMID: 19743859
Study Type : Review
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)

Pubmed Data : Anal Chim Acta. 2006 May 10;567(1):4-12. Epub 2006 Mar 27. PMID: 17723372
Study Type : Commentary

Pubmed Data : Environ Sci Technol. 2008 Dec 15;42(24):9437-42. PMID: 19174928
Study Type : In Vitro Study
Additional Links
Problem Substances : Perchlorate : CK(100) : AC(28)
Adverse Pharmacological Actions : Bioaccumulator : CK(102) : AC(23)

Related Blogs

Written by Sayer Ji
Perchlorate is an environmental pollutant primarily associated with releases by defense contractors, military operations and aerospace programs, as it is a key ingredient in rocket fuel. It is now found in virtually all humans tested, and it is continually making its way up the food chain through ground and drinking water, into feed and edible plants, animals products, milk and breast milk - contaminating conventional and organically grown food, alike. It is now distributed widely throughout...

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