Rofecoxib

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10 Diseases Researched for Rofecoxib

Name	AC	CK
Myocardial Infarction	4	50
Cardiac Mortality	3	40
Cardiovascular Diseases	3	40
Coronary Artery Disease	2	30
Abortion: Spontaneous	1	10
Cardiac Arrest	1	10
Drug-Induced Toxicity	1	10
Heart Failure	1	10
Miscarriage	1	10
NSAID-induced toxicity	1	10

2 Adverse Pharmacological Actions Researched for Rofecoxib

Name	AC	CK	Focus
Cardiotoxic	3	40
Teratogenic	1	10

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

View the Evidence:
6 Abstracts with Rofecoxib Research

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[+]

Nonsteroidal antinflammatory drugs increase cardiovascular events in patients after hospitalization for serious coronary heart disease.May 01, 2009

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Pubmed Data : Circ Cardiovasc Qual Outcomes. 2009 May;2(3):155-63. Epub 2009 May 5. PMID: 20031832

Article Published Date : May 01, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Cardiac Mortality , Cardiovascular Diseases, Coronary Artery Disease, Myocardial Infarction

Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib

Adverse Pharmacological Actions : Cardiotoxic

[+]

NSAIDs are associated with an increased risk of myocardial infarction and death. Feb 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Pharmacol Ther. 2009 Feb;85(2):190-7. Epub 2008 Nov 5. PMID: 18987620

Article Published Date : Feb 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cardiac Mortality , Cardiovascular Diseases, Myocardial Infarction

Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib

[+]

NSAIDs are frequently used in patients with heart failure and are associated with increased risk of death and cardiovascular morbidity.Jan 26, 2009

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Pubmed Data : Arch Intern Med. 2009 Jan 26;169(2):141-9. PMID: 19171810

Article Published Date : Jan 26, 2009

Study Type : Human Study

Additional Links

Diseases : Heart Failure, Myocardial Infarction

Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib

[+]

Taking non-aspirin NSAIDs in early pregnancy doubles the risk of miscarriage. Jan 01, 2011

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Pubmed Data : BMJ. 2011 ;343:d5769. Epub 2011 Sep 9. PMID: 21908536

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous, Drug-Induced Toxicity , Miscarriage

Pharmacological Actions : Teratogens

Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib

Adverse Pharmacological Actions : Teratogenic

[+]

The use of rofecoxib, valdecoxib, and indomethacin increases the risk of cardiovascular disease.Nov 01, 2009

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Pubmed Data : Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):1053-63. PMID: 19637402

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cardiac Mortality , Cardiovascular Diseases, Coronary Artery Disease, Myocardial Infarction

Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib, Valdecoxib

Adverse Pharmacological Actions : Cardiotoxic

[+]

Use of non-selective NSAIDs was associated with an increased early risk of out-of-hospital cardiac arrest.Dec 25, 2016

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Pubmed Data : Eur Heart J Cardiovasc Pharmacother. 2016 Dec 26. Epub 2016 Dec 26. PMID: 28025218

Article Published Date : Dec 25, 2016

Study Type : Human Study

Additional Links

Diseases : Cardiac Arrest, NSAID-induced toxicity

Additional Keywords : Increased Risk

Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib

Adverse Pharmacological Actions : Cardiotoxic

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 6 Abstracts with Rofecoxib Research

Limited to Members Only

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Nonsteroidal antinflammatory drugs increase cardiovascular events in patients after hospitalization for serious coronary heart disease.May 01, 2009

Click here to read the entire abstract

NSAIDs are associated with an increased risk of myocardial infarction and death. Feb 01, 2009

Click here to read the entire abstract

NSAIDs are frequently used in patients with heart failure and are associated with increased risk of death and cardiovascular morbidity.Jan 26, 2009

Click here to read the entire abstract

Taking non-aspirin NSAIDs in early pregnancy doubles the risk of miscarriage. Jan 01, 2011

Click here to read the entire abstract

The use of rofecoxib, valdecoxib, and indomethacin increases the risk of cardiovascular disease.Nov 01, 2009

Click here to read the entire abstract

Use of non-selective NSAIDs was associated with an increased early risk of out-of-hospital cardiac arrest.Dec 25, 2016

Click here to read the entire abstract

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Rofecoxib

View the Evidence:
6 Abstracts with Rofecoxib Research