Roundup (herbicide)

Roundup (herbicide)

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View the Evidence: Problem Substances

Roundup herbicide exhibits significant toxicity in larval amphibians, killing 50% of test species after 96 hours at concentrations that range between .8 mg and 3.2 mg per Liter.

Pubmed Data : Environ Toxicol Chem. 2009 Sep;28(9):2004-8. PMID: 19405783
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant : CK(32) : AC(15)
Problem Substances : Glyphosate : CK(365) : AC(116), Polyoxyethylene amine : CK(12) : AC(7), Roundup (herbicide) : CK(365) : AC(116)

Roundup herbicide may contribute to widespread amphibian declines due to its significant toxicity on tadpoles.

Pubmed Data : Environ Pollut. 2010 Aug;158(8):2610-7. Epub 2010 Jun 11. PMID: 20541298
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant : CK(32) : AC(15)
Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)

Roundup is able to induce a dose-dependent formation of DNA adducts in the kidneys and liver of mice.

Pubmed Data : Environ Mol Mutagen. 1998 ;31(1):55-9. PMID: 9464316
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Diseases : DNA damage : CK(711) : AC(293)
Problem Substances : Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Genotoxic : CK(146) : AC(61)

Roundup(®) formulation exhibits genotoxicity in blood cells of fish (Anguilla anguilla).

Pubmed Data : Ecotoxicology. 2012 Jul ;21(5):1381-90. Epub 2012 Apr 8. PMID: 22526921
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate : CK(365) : AC(116)
Adverse Pharmacological Actions : Aquacidal : CK(2) : AC(1), Genotoxic : CK(146) : AC(61)

Roundup(®) has an inhibitory effect on microbial growth and a microbicide effect at lower concentrations than those recommended in agriculture.

Pubmed Data : Curr Microbiol. 2012 Feb 24. Epub 2012 Feb 24. PMID: 22362186
Article Published Date : Feb 24, 2012
Study Type : Environmental
Additional Links
Additional Keywords : Ecotoxicology: Glyphosate : CK(17) : AC(9)
Problem Substances : Glyphosate : CK(365) : AC(116)

Study: Oral and intracheal toxicities of Roundup and its components.

Pubmed Data : Vet Hum Toxicol. 1997 Jun;39(3):147-51. PMID: 9167243
Article Published Date : Jun 01, 1997
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate : CK(365) : AC(116), Polyoxyethylene amine : CK(12) : AC(7), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

The glyphosate herbicide Roundup exhibits teratogenic potential in rats.

Pubmed Data : Toxicol Lett. 2003 Apr 30;142(1-2):45-52. PMID: 12765238
Article Published Date : Apr 30, 2003
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81), Teratogenic : CK(304) : AC(59)

The glyphosate-based formula Roundup sigificantly increases the bioaccumulation of mercury in water fleas.

Pubmed Data : Environ Pollut. 2005 Nov;138(1):59-68. PMID: 15878796
Article Published Date : Nov 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Mercury Poisoning : CK(162) : AC(44)
Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

The herbicide glyphosate (and its metabolite) was found in all plant species tested.

Pubmed Data : J Agric Food Chem. 2008 Mar 26 ;56(6):2125-30. Epub 2008 Feb 26. PMID: 18298069
Article Published Date : Mar 26, 2008
Study Type : Environmental
Additional Links
Problem Substances : Aminomethylphosphonic acid : CK(12) : AC(5), Glyphosate : CK(365) : AC(116)

The herbicide Roundup may cause disorder in the morphophysiology of the male genital system of animals.

Pubmed Data : Reprod Toxicol. 2007 Feb;23(2):182-91. Epub 2006 Nov 11. PMID: 17166697
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Endocrine Diseases : CK(13) : AC(3), Hormonal Disorders: Children : CK(14) : AC(3)
Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81)

Roundup exposure may adversely affect human reproduction and fetal development in case of contamination.

Pubmed Data : Arch Environ Contam Toxicol. 2007 Jul;53(1):126-33. Epub 2007 May 4. PMID: 17486286
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Diseases : Endocrine Diseases : CK(13) : AC(3), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Aromatase Disruptor : CK(1) : AC(1), Endocrine Disruptor : CK(478) : AC(81)

"2,4-Dichlorophenoxyacetic acid (2,4-D)–resistant crops and the potential for evolution of 2,4-D–resistant weeds."

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2011 Mar 15 ;108(11):E37; author reply E38. Epub 2011 Mar 3. PMID: 21372267
Article Published Date : Mar 15, 2011
Study Type : Plant Study
Additional Links
Problem Substances : 2, 2,4-Dichlorophenoxyacetic acid : CK(11) : AC(2), Glyphosate : CK(365) : AC(116)

"A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels."

Pubmed Data : Toxicol In Vitro. 2011 Dec 19. Epub 2011 Dec 19. PMID: 22200534
Article Published Date : Dec 19, 2011
Study Type : In Vitro Study
Additional Links
Diseases : Glyphosate Toxicity : CK(22) : AC(12), Testosterone: Too Low : CK(369) : AC(70)
Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Endocrine Disruptor: Testes : CK(1) : AC(1)

"Developmental and reproductive outcomes in humans and animals after glyphosate exposure: a critical analysis."

Pubmed Data : J Toxicol Environ Health B Crit Rev. 2012 ;15(1):39-96. PMID: 22202229
Article Published Date : Jan 01, 2012
Study Type : Review
Additional Links
Additional Keywords : junk science
Problem Substances : Glyphosate : CK(365) : AC(116)

"Effect of pesticides on cell survival in liver and brain rat tissues."

Pubmed Data : Ecotoxicol Environ Saf. 2009 Oct ;72(7):2025-32. Epub 2009 Jun 2. PMID: 19493570
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Glyphosate Toxicity : CK(22) : AC(12), Lipid Peroxidation : CK(403) : AC(127), Neurotoxicity : CK(37) : AC(15), Parkinson Disease : CK(543) : AC(79), Pesticide Toxicity : CK(147) : AC(45)
Problem Substances : Dimethoate : CK(3) : AC(1), Glyphosate : CK(365) : AC(116), Pesticides : CK(699) : AC(70), Zineb : CK(1) : AC(1)
Adverse Pharmacological Actions : Apoptotic : CK(8) : AC(7), Hepatotoxic : CK(283) : AC(80), Neurotoxic : CK(1076) : AC(179), Oxidant : CK(104) : AC(37)

"Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition."

Pubmed Data : Toxicol Sci. 2004 Dec ;82(2):436-42. Epub 2004 Sep 16. PMID: 15375296
Article Published Date : Dec 01, 2004
Study Type : In Vitro Study
Additional Links
Problem Substances : Glyphosate : CK(365) : AC(116)
Adverse Pharmacological Actions : Cell Cycle Inhibitor : CK(3) : AC(1), Cytotoxic : CK(73) : AC(35)

"Glyphosate and pendimethalin could potentially be present in high concentrations (>0.1 μg L(-1)) in both water originating from the drainage system and the shallow groundwater located at the depth of the drainage system."

Pubmed Data : Chemosphere. 2011 Jul ;84(4):471-9. Epub 2011 Apr 9. PMID: 21481435
Article Published Date : Jul 01, 2011
Study Type : Review
Additional Links
Additional Keywords : Groundwater Contamination : CK(6) : AC(4)
Problem Substances : Glyphosate : CK(365) : AC(116)

"Pool of resistance mechanisms to glyphosate in Digitaria insularis."

Pubmed Data : J Agric Food Chem. 2012 Jan 18 ;60(2):615-22. Epub 2012 Jan 5. PMID: 22175446
Article Published Date : Jan 17, 2012
Study Type : Plant Study
Additional Links
Additional Keywords : glyphosate metabolites
Problem Substances : Aminomethylphosphonic acid : CK(12) : AC(5), Glyphosate : CK(365) : AC(116)

Related Blogs

Glyphosate: A Trajectory of Human Misery
Written by Heidi Stevenson
Glyphosate has likely caused more damage to human health than any other chemical ever produced. Indeed, it is probably a cause of the explosion in chronic diseases. Surely civilization cannot be maintained when the average person is irrevocably ill. This trajectory of human misery must come to an end.
Research: Roundup Herbicide Toxicity Vastly Underestimated
Written by Sayer Ji, Founder
Herbicides used in GM farming like Roundup have long been understood to be toxic, that much is true, but the ongoing debate rages over to what degree they are toxic. Shocking research indicates that the so-called "inert" ingredients in these glyphosate formulations are actually highly toxic, and amplify the toxicity of the active ingredient.
Roundup Herbicide Linked To Parkinson's-Related Brain Damage
Written by Sayer Ji, Founder
Alarming new research published in the journal Neurotoxicology and Teratology sheds new light on the emerging connection between glyphosate, the active ingredient in Roundup herbicide, and neurodegenerative conditions such as Parkinson's disease and Parkinsonian disorders.

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