Statin Drugs

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Quick Summary: 333 associated Diseases
NameCumulative KnowledgeArticle CountFocus Articles
Statin-Induced Pathologies2398308 |
Myopathies39646 |
Chemically-Induced Liver Damage34026 |
High Cholesterol22812 |
Drug-Induced Nutrient Depletion: Statin Drugs21325 |
Rhabdomyolysis20936 |
Diabetes Mellitus: Type 217210 |
Coenzyme Q10 Deficiency14411 |
Cancers: All1315 |
Drug-Induced Toxicity 12612 |
Coronary Artery Disease1218 |
Pancreatitis11215 |
Cataract1097 |
Cardiovascular Diseases1046 |
Mitochondrial Dysfunction 9914 |
Oxidative Stress986 |
Myalgias9711 |
Peripheral Neuropathies979 |
Hyperlipidemia935 |
Mitochondrial Myopathies858 |
Cognitive Decline/Dysfunction817 |
Insulin Resistance815 |
Creatine Phosphokinase (CK): Elevated808 |
Testosterone: Too Low704 |
GGT655 |
Memory Disorders656 |
Erectile Dysfunction647 |
Kidney Failure612 |
Esophageal Cancer601 |
Liver Damage564 |
Neuropathies5410 |
Low Testosterone536 |
Hyperglycemia514 |
Muscle Damage: Exercise-Induced515 |
Athletic Performance504 |
Blood Platelet Disorders501 |
Hepatitis: Cholestatic4710 |
Elevated: ALT462 |
Elevated: Creatinine Kinase462 |
Hypertension443 |
Cholestasis439 |
Polyneuropathies432 |
Liver Disease422 |
Diabetes Mellitus: Type 1413 |
Intracerebral Hemorrhage414 |
AST: Elevated401 |
Birth Defects408 |
Diabetes Insipidus401 |
Diabetes Mellitus: Type 2: Prevention402 |
Fibromyalgia401 |
Hemodialysis402 |
Liver Failure: Drug Induced401 |
Myopathy404 |
Hepatitis: Autoimmune 375 |
Autoimmune Diseases355 |
Immune Disorders: Low Immune Function355 |
Kidney Failure: Acute355 |
Cholesterol: Oxidation343 |
Lupus-Like Syndrome325 |
Cardiomyopathy313 |
Depression314 |
Dietary Fatty Acid Imbalance: Omega3/Omega6 Ratio313 |
Muscle Soreness312 |
Aggression303 |
Aldosterone levels: Low301 |
Breast Cancer303 |
Cardiac Mortality 301 |
Copper Deficiency301 |
Diabetes: Cardiovascular Illness302 |
Eczema301 |
Heart Failure307 |
Hormonal Perturbations: Dopamine Elevation301 |
Hormonal Perturbations: Homovanillic acid (HVA) Elevations301 |
Insomnia302 |
Kidney Diseases301 |
Organ Transplantation: Heart301 |
Psoriasis301 |
Renal Failure: Chronic301 |
Sperm Quality: Low302 |
Zinc Deficiency301 |
Myositis295 |
Kidney Damage: Drug-Induced274 |
Neurotoxicity2710 |
Prenatal Chemical Exposures263 |
Psychiatric Disorders263 |
Sleep Disorders264 |
Hypothyroidism254 |
Death: Statin-Induced244 |
Endothelial Dysfunction242 |
Hepatitis246 |
Interstitial Lung Diseases232 |
Mitochondrial Diseases232 |
Muscle Disorders233 |
DNA damage223 |
Lichenoid Dermatitis214 |
Omega-3 Fatty Acid Deficiency212 |
Amyotrophic Lateral Sclerosis202 |
Aortic Stenosis201 |
Arterial Calcification202 |
Blood Sugar Problems201 |
Bone Fractures202 |
Colorectal Cancer202 |
DHEA: Low201 |
Dermatomyositis205 |
Exercise-Induced Tissue Damage201 |
Gastrointestinal Complaints201 |
Infants: Low Birth Weight201 |
Muscle Fatigue202 |
Myasthenia Gravis203 |
Myocardial Infarction201 |
Pneumonia201 |
Polymyositis205 |
Premature Birth201 |
Prostate Cancer202 |
Sepsis201 |
Stroke202 |
Testicular Cancer201 |
Neurodegenerative Diseases184 |
Anxiety Disorders162 |
Lens Diseases164 |
Lichen Planus162 |
Lupus Erythematosus: Cutaneous162 |
Memory Disorders: Drug-Induced162 |
Psychological Well-Being162 |
Systemic Lupus Erythematosus163 |
Jaundice153 |
Liver Damage: Drug-Induced154 |
Multi-Organ Failure153 |
Brain Damage145 |
Infertility: Male142 |
Dementia132 |
Impotence132 |
Memory Loss132 |
Neuromuscular Diseases132 |
Nightmare132 |
Polymyalgia Rheumatica132 |
Gynecomastia122 |
Tendon Rupture122 |
Thrombocytopenia122 |
Demyelinating Diseases116 |
Pregnancy: Environmental Exposures113 |
Skin Cancer112 |
Stroke: Attenuation/Recovery 112 |
Violence112 |
Alzheimer's Disease101 |
Ammonia: Elevated101 |
Aneurysmal subarachnoid hemorrhage (SAH)101 |
Aortic Calcification101 |
Arteriovenous Fistula101 |
Bacterial Infections and Mycoses101 |
Balance Disorders101 |
Bilirubin: Low101 |
Bladder Cancer101 |
Blood Lactate/ Pyruvate Ratio: Elevated101 |
Breast Cancer: Ductal Carcinoma In Situ101 |
Breast Cancer: Invasive Lobular Carcinoma (ILC)101 |
C-Reactive Protein101 |
Calcium Homeostasis: Impairment101 |
Cerebral Hemorrhage101 |
Chemotherapy-Induced Toxicity101 |
Cholesterol: High101 |
Cough101 |
Domestic Violence101 |
Dry Mouth101 |
Dysphagia101 |
Ectopic Calcification101 |
Endothelial Damage101 |
Family Violence101 |
Fatigue101 |
Herpes Zoster101 |
Herpes family viruses101 |
Hip Fracture101 |
Hypogonadism101 |
IGF2 and IGFBP3: Low101 |
Infection: Bloodstream101 |
Inflammation101 |
Insulin-Like Growth Factor (IGF): Low101 |
Irritability101 |
Isoprostane 8-epi-PGF2alpha: Elevated101 |
Kidney Cancer101 |
Libido: Low101 |
Lung Cancer101 |
Lupus Erythematosus: Systemic101 |
Macular Degeneration101 |
Malignant Hyperthermia101 |
McArdle Disease101 |
Melanoma101 |
Microalbuminuria101 |
Multiple Myeloma101 |
Muscle Soreness: Exercise-Induced101 |
Muscle Stiffness: Exercise-Induced101 |
Myocardial Ischemia102 |
Myotoxicity101 |
Neuropsychological Dysfunction: Psychomotor Speed101 |
Oral Symptoms101 |
Osteoarthritis: Knee101 |
Pancreatic Cancer101 |
Prostatectomy101 |
Radical Prostatectomy101 |
Rheumatoid Arthritis101 |
Shingles101 |
Skeletal Muscle: Changes to MHC I expression102 |
Sperm Count: Low101 |
Thrombosis101 |
Vasospasm: Intracranial101 |
Vitamin D Deficiency101 |
Weight Problems: Drug-Induced101 |
A1C91 |
Bile Duct Injury92 |
Diabetes: Glycation/A1C91 |
Eosinophilia92 |
Eye Diseases92 |
Lactic Acidosis92 |
Lens Damage92 |
Lung Diseases: Interstitial93 |
Myositis Migrans91 |
Myositis: Focal92 |
Skeletal Muscle Changes: Endoplasmic Reticulum Stress91 |
Lipid Peroxidation82 |
Abortion: Spontaneous72 |
Multiple Sclerosis73 |
Pneumonia: Interstitial72 |
Alopecia61 |
Ataxia61 |
Bipolar Disorder61 |
Blepharoptosis61 |
Blood-Brain-Barrier Disorders61 |
Cheilitis61 |
Compartment Syndromes61 |
Cutaneous Eruptions61 |
Cystitis: Hemorrhagic61 |
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)61 |
Gitelman's syndrome (False Presentation)61 |
Mood Disorders61 |
Multiple Mononeuropathy61 |
Myoglobinuria61 |
Organ Transplantation: Liver61 |
Paranoia61 |
Perioperative Care61 |
Rhabdomyolysis: Fatal62 |
Senile Paranoid Dementia61 |
Tendinopathy61 |
Toxic Epidermal Necrolysis61 |
Ulcerative Colitis61 |
Vasculitis61 |
Aging52 |
Congestive Heart Failure52 |
Mineral Deficiencies: Selenium54 |
Skin Problems: Compromised Barrier Function52 |
Alcohol Toxicity 41 |
Drug-Induced Toxicity: Indomethacin41 |
Gastrointestinal Diseases41 |
Immune Dysregulation: TH1/TH2 imbalance41 |
Infertility41 |
Infertility: Female41 |
Lung Diseases41 |
NSAID-induced toxicity 41 |
Organ Transplantation41 |
Ovarian Diseases42 |
Pancreatic Diseases41 |
Proteoglycan Expression: Down-Regulation of Chondroitin Sulfate41 |
Proteoglycan Expression: Pathological41 |
Respiratory Diseases41 |
Spinal Cord Injuries41 |
Testicular Diseases41 |
Acute Respiratory Distress Syndrome31 |
Acute generalized exanthematous pustulosis (AGEP) 31 |
Alkaline Phosphatase: Elevated31 |
Appetite Disorders: Loss/Lack of 31 |
Arthralgia31 |
Bilirubin: Elevated31 |
Bullous Dermatosis31 |
Cholangiolitis31 |
Colitis31 |
Dermatitis: Actinic31 |
Gastric Ulcer31 |
Guillain-Barre Syndrome31 |
Headache: Altitude-Induced31 |
Hepatitis: Acute31 |
Hyperkalemia31 |
Hypersensitivity31 |
Hyperthermia31 |
Hypotension31 |
Intraocular Hemorrhage31 |
Kidney Failure: Chronic31 |
Kidney Transplant31 |
Lens Opacities31 |
Low Libido31 |
Lupus Erythematosus: Cutaneous: Subacute31 |
Melas Syndrome31 |
Musculoskeletal Complaints31 |
Neuroleptic Malignant Syndrome31 |
Ovulation Disorders31 |
Pleurisy31 |
Pneumonitis31 |
Pneumonitis: Hypersensitivity Type31 |
Presymptomatic Metabolic Myopathy 31 |
Seizures31 |
Sleep Apnea31 |
Smell Disorders31 |
Tendon Injury31 |
Tendon Rupture: Spontaneous Bilateral Quadriceps31 |
Urticarial Vasculitis31 |
Alveolar Capillary Congestion21 |
Cochlear Neuronal Damage21 |
Hearing Disorders21 |
Hypoadrenalism21 |
Infant Mortality 21 |
Influenza A21 |
Insulin-like Growth Factor-1: Signaling Abnormalities22 |
Lethargy21 |
Lung Damage21 |
Neurologic Disorders21 |
Optic Nerve Diseases21 |
Proteinuria21 |
Pulmonary Alveolar Proteinosis21 |
Skeletal Muscle Changes: Ultrastructural Changes21 |
Tumors21 |
Elderly: Age Specific Diseases11 |
Ichthyosis11 |
Immune-Mediated Necrotizing Myopathies 11 |
Kidney Damage11 |
Molecular Pathologies: Dolichol Depletion11 |
Myopathy: Iatrogenic11 |
Neurodevelopmental Disorders11 |
Neuromyotoxicity11 |
Ovarian Failure11 |
Prostate Diseases11 |
Skeletal Muscle: Drug-Induced Changes11 |
Squamous cell carcinoma11 |
Stroke: Hemorrhagic 11 |
Suicidal Behavior11 |
Vitamin E Deficiency11 |

View the Evidence: Problem Substances

Pubmed Data : Am J Cardiol. 2010 Dec 1;106(11):1634-9. Epub 2010 Oct 14. PMID: 21094366
Study Type : Meta Analysis

Pubmed Data : Heart Lung Circ. 2009 Oct;18(5):343-6. Epub 2009 Jul 7. PMID: 19586799
Study Type : Meta Analysis
Additional Links
Problem Substances : Simvastatin : CK(723) : AC(146)
Adverse Pharmacological Actions : Carcinogenic : CK(951) : AC(135)

Pubmed Data : JAMA. 2011 Jun 22;305(24):2556-64. PMID: 21693744
Study Type : Meta Analysis

Pubmed Data : Drug Saf. 2008;31(12):1115-23. PMID: 19026028
Study Type : Meta Analysis
Additional Links

Pubmed Data : Fam Pract. 2002 Feb ;19(1):95-8. PMID: 11818357
Study Type : Meta Analysis

Pubmed Data : Curr Opin Lipidol. 2007 Aug;18(4):401-8. PMID: 17620856
Study Type : Meta Analysis
Additional Links
Adverse Pharmacological Actions : Myotoxicity : CK(327) : AC(80)

Pubmed Data : Drug Saf. 2006 ;29(12):1123-32. PMID: 17147459
Study Type : Meta Analysis

Pubmed Data : CMAJ. 2007 Feb 27 ;176(5):649-54. PMID: 17325332
Study Type : Meta Analysis

Pubmed Data : Diabetes Res Clin Pract. 2010 Jan ;87(1):98-107. Epub 2009 Nov 12. PMID: 19913318
Study Type : Meta Analysis

Pubmed Data : QJM. 2011 Sep 14. Epub 2011 Sep 14. PMID: 21920996
Study Type : Meta Analysis

Pubmed Data : Curr Opin Cardiol. 2011 Jul;26(4):342-7. PMID: 21499090
Study Type : Meta Analysis

Pubmed Data : Chest. 2008 Oct;134(4):824-30. Epub 2008 Aug 8. PMID: 18689579
Study Type : Meta Analysis

Pubmed Data : Eur J Clin Pharmacol. 2011 Nov 15. Epub 2011 Nov 15. PMID: 22083167
Study Type : Meta Analysis
Additional Links

Pubmed Data : BMC Med. 2013 Feb 28 ;11(1):57. Epub 2013 Feb 28. PMID: 23448151
Study Type : Meta Analysis
Additional Links
Adverse Pharmacological Actions : Endocrine Disruptor: Testes : CK(1) : AC(1)

Pubmed Data : J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID: 17662392
Study Type : Meta Analysis

Pubmed Data : QJM. 2010 Oct 7. Epub 2010 Oct 7. PMID: 20934984
Study Type : Meta Analysis

Pubmed Data : Am J Cardiovasc Drugs. 2015 Jul 4. Epub 2015 Jul 4. PMID: 26141958
Study Type : Meta Analysis
Additional Links

Pubmed Data : Arch Intern Med. 2001 Sep 10 ;161(16):2021-6. PMID: 11525705
Study Type : Human Study

Pubmed Data : Eur J Intern Med. 2005 Jun ;16(3):192-194. PMID: 15967335
Study Type : Human Study



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