Sucralose

Sucralose

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Related Topics

Sucralose is a Sub of the following Topic

Quick Summary: 6 associated Diseases
NameCumulative KnowledgeArticle CountFocus Articles
Immune Disorders: Low Immune Function21Log in | Sign up
Crohn's Disease11Log in | Sign up
DNA damage11Log in | Sign up
Inflammatory Bowel Diseases11Log in | Sign up
Migraine Disorders11Log in | Sign up
Ulcerative Colitis11Log in | Sign up
View the Evidence: Problem Substances

Sucralose causes bowel enlargement, kidney mineralization and abnormal pelvic tissue changes in rats.

Pubmed Data : Food Chem Toxicol. 1990 Jun;28(6):449-55. PMID: 2210518
Article Published Date : Jun 01, 1990
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose : CK(15) : AC(10)

Sucralose has been demonstrated to be carcinogenic and otherwise toxic in rats.

Pubmed Data : Food Chem Toxicol. 2000;38 Suppl 2:S71-89. PMID: 10882819
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose : CK(15) : AC(10)

Sucralose reduces the weight of spleen and thymus in rats.

Pubmed Data : Food Chem Toxicol. 2000;38 Suppl 2:S53-69. PMID: 10882818
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115)
Problem Substances : Sucralose : CK(15) : AC(10)

Sucralose represents an ecotoxicological contaminant that significantly affects the behavior of animals.

Pubmed Data : Chemosphere. 2012 Jan ;86(1):50-5. Epub 2011 Sep 28. PMID: 21955350
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Additional Keywords : Environmental Pollutant : CK(32) : AC(15), Environmental Toxicity : CK(6) : AC(4)
Problem Substances : Sucralose : CK(15) : AC(10)

The administration of Splenda (sucralose) to rats at a dose far below the US FDA Acceptable Daily intake for sucralose exhibited numerous adverse effects in the gastrointesintal tract of male rats.

Pubmed Data : J Toxicol Environ Health A. 2008;71(21):1415-29. PMID: 18800291
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Problem Substances : Sucralose : CK(15) : AC(10)

Increased sucralose consumption may explain why Canada has the highest incidence of inflammatory bowel disease in the world.

Pubmed Data : Can J Gastroenterol. 2011 Sep ;25(9):511. PMID: 21912763
Article Published Date : Sep 01, 2011
Study Type : Review
Additional Links
Diseases : Crohn's Disease : CK(361) : AC(22), Inflammatory Bowel Diseases : CK(1210) : AC(109), Ulcerative Colitis : CK(461) : AC(40)
Problem Substances : Sucralose : CK(15) : AC(10)
Adverse Pharmacological Actions : Inflammatory : CK(135) : AC(37)

Sucralose consumption may contribute to inflammatory bowel disease.

Pubmed Data : World J Gastroenterol. 2012 Apr 21 ;18(15):1708-22. PMID: 22553395
Article Published Date : Apr 21, 2012
Study Type : Review
Additional Links
Diseases : Clostridium Enterocolitis : CK(1) : AC(1), Crohn's Disease : CK(361) : AC(22), Inflammatory Bowel Diseases : CK(1210) : AC(109)
Problem Substances : Sucralose : CK(15) : AC(10)
Adverse Pharmacological Actions : Inflammatory : CK(135) : AC(37)

Sucralose is found in drinking water tested with a low rate of removal (11%) and serving 28 million people.

Pubmed Data : Environ Sci Technol. 2011 Aug 31. Epub 2011 Aug 31. PMID: 21879743
Article Published Date : Aug 31, 2011
Study Type : Review
Additional Links
Problem Substances : Sucralose : CK(15) : AC(10)

Sucralose is largely resistant to natural breakdown processes and accumulates in the environment with unknown consequences for human and environmental health.

Pubmed Data : Environ Sci Technol. 2011 Jan 14. [Epub ahead of print]. PMID: 21235203
Study Type : In Vitro Study
Additional Links
Problem Substances : Sucralose : CK(15) : AC(10)

Sucralose may be a migraine trigger.

Pubmed Data : Headache. 2006 Sep;46(8):1303-4. PMID: 16942478
Article Published Date : Sep 01, 2006
Study Type : Commentary
Additional Links
Diseases : Migraine Disorders : CK(455) : AC(54)
Problem Substances : Sucralose : CK(15) : AC(10)

Various food additives, preservatives, fungicides and artificial sweeteners have been demonstrated to have the potential to damage DNA in gastrointestinal organs.

Pubmed Data : Mutat Res. 2002 Aug 26;519(1-2):103-19. PMID: 12160896
Article Published Date : Aug 26, 2002
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage : CK(680) : AC(293)
Problem Substances : Biphenyl : CK(1) : AC(1), Butylated hydroxyanisole (BHA) : CK(9) : AC(7), Butylated Hydroxytoluene (BHT) : CK(74) : AC(44), Saccharin : CK(34) : AC(6), Sodium Cyclamate : CK(15) : AC(4), Sodium o-phenylphenol : CK(1) : AC(1), Sucralose : CK(15) : AC(10), Thiabendazole : CK(1) : AC(1)

Related Blogs

The Bitter Truth About Splenda
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If you were told to ingest a biologically alien synthetic chemical whose presence on this planet did not predate 1976, and whose structure is only a few atoms away from the deadly pesticide DDT, and you knew that not only were there no long term human safety studies performed on it, but that it had been already proven in tests to have over a dozen serious adverse health effects, would you consume it?
Sweet! Dieting without Deprivation
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