Vaccine Adjuvants

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52 Diseases Researched for Vaccine Adjuvants
NameACCKFocus
Neurodevelopmental Disorders17161Locked
Autism Spectrum Disorders22127Locked
Vaccine-induced Toxicity 20102Locked
Autism992Locked
Tic Disorders461Locked
Macrophagic myofasciitis 648Locked
Learning disorders342Locked
Attention Deficit Disorder341Locked
Autoimmune Diseases1041Locked
Mental Retardation340Locked
Cognitive Decline/Dysfunction230Locked
Speech Disorders230Locked
Mercury Poisoning728Locked
Gulf War Syndrome423Locked
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)321Locked
Developmental Disorder: Children321Locked
Oxidative Stress621Locked
Childhood Chemical Exposures120Locked
Emotional Disorders120Locked
Immune Dysregulation: TH1/TH2 imbalance120Locked
Infant Mortality 120Locked
Infantile Spasms120Locked
Seizures120Locked
Sexual Development: Dysfunctions and Abnormalities120Locked
Aluminum Toxicity 517Locked
Mitochondrial Dysfunction 215Locked
Infant Chemical Exposures212Locked
Attention Deficit Disorder with Hyperactivity211Locked
Anthrax110Locked
Ataxia: Cerebellar110Locked
Atopic Dermatitis110Locked
Atopic Disease110Locked
Atopic Hypersensitivity110Locked
Detoxification: Impaired110Locked
Personality Disorder: Borderline110Locked
Chronic Fatigue Syndrome27Locked
Pseudolymphoma16Locked
Hypersensitivity15Locked
Neurodegenerative Diseases25Locked
Liver Damage14Locked
Systemic Lupus Erythematosus14Locked
Excitotoxicity 23Locked
Amygdala: Damage/Abnormalities12Locked
DNA damage22Locked
Febrile Seizures12Locked
Lupus Erythematosus: Systemic12Locked
Multiple Sclerosis12Locked
Neurotoxicity22Locked
Fibromyalgia11Locked
Immune Disorders: Low Immune Function11Locked
Inflammation11Locked
Lymphoma11Locked
18 Adverse Pharmacological Actions Researched for Vaccine Adjuvants
NameACCKFocus
Neurotoxic20159Locked
Immunotoxic842Locked
Inflammatory834Locked
Endocrine Disruptor222Locked
Immunoreactive26Locked
Hepatotoxic14Locked
Carcinogenic12Locked
Cytotoxic12Locked
Hematoxic12Locked
Hemolytic12Locked
Immunosuppressive12Locked
Irritant12Locked
Tumorigenic12Locked
Apoptotic11Locked
Cytotoxicity11Locked
Excitotoxic11Locked
Genotoxic11Locked
Hypermethylation11Locked
Related Topics

The Following are Sub-Topics of Vaccine Adjuvants

View the Evidence:
237 Abstracts with Vaccine Adjuvants Research

[+]

As thimerosal was removed from childhood vaccines, the number of neurodevelopmental disorders decreased in the US.Jun 01, 2006

Pubmed Data : Med Sci Monit. 2006 Jun;12(6):CR231-9. Epub 2006 May 29. PMID: 16733480
Article Published Date : Jun 01, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Childhood Chemical Exposures, Neurodevelopmental Disorders, Vaccine-induced Toxicity
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Exposure to mercury from thimerosal-containing vaccines was associcated with an increased risk of neurodevelopmental problems in infants from 1992-1997.Apr 01, 2005

Pubmed Data : Med Sci Monit. 2005 Apr;11(4):CR160-70. Epub 2005 Mar 24. PMID: 15795695
Article Published Date : Apr 01, 2005
Study Type : Meta Analysis
Additional Links
Diseases : Attention Deficit Disorder, Learning disorders, Neurodevelopmental Disorders, Seizures, Speech Disorders, Tic Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Rates of autism, speech disorders, mental retardation, infantile spasms, and thinking abnormalities were higher in children exposured to higher thimerosal levels.Aug 01, 2006

Pubmed Data : J Toxicol Environ Health A. 2006 Aug;69(15):1481-95. PMID: 16766480
Article Published Date : Aug 01, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Autism, Cognitive Decline/Dysfunction, Infantile Spasms, Mental Retardation, Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal exposure is associated with increasing trends of premature puberty in 278,624 subjects from 1990-1996.Apr 01, 2010

Pubmed Data : Indian J Med Res. 2010 Apr;131:500-7. PMID: 20424300
Article Published Date : Apr 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Sexual Development: Dysfunctions and Abnormalities
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Thimersol exposure in infants is associated with an increase risk for tics. Sep 01, 2004

Pubmed Data : Pediatrics. 2004 Sep;114(3):584-91. PMID: 15342825
Article Published Date : Sep 01, 2004
Study Type : Meta Analysis
Additional Links
Diseases : Tic Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimersol exposure in infants significantly increases neurodevelopment disorders in infants, e.g. autism, autism spectrum disorders, tics, attention deficit disorder, and emotional disturbances.Aug 15, 2008

Pubmed Data : J Neurol Sci. 2008 Aug 15;271(1-2):110-8. Epub 2008 May 15. PMID: 18482737
Article Published Date : Aug 15, 2008
Study Type : Meta Analysis
Additional Links
Diseases : Attention Deficit Disorder, Autism, Autism Spectrum Disorders, Emotional Disorders, Neurodevelopmental Disorders
Problem Substances : Mercury, Thimerosal
[+]

Thimersol exposure is associated with tics and delayed language acquisition in infants.Nov 01, 2003

Pubmed Data : Pediatrics. 2003 Nov;112(5):1039-48. PMID: 14595043
Article Published Date : Nov 01, 2003
Study Type : Meta Analysis
Additional Links
Diseases : Learning disorders, Neurodevelopmental Disorders, Tic Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

2001: Depending on the immunization schedule, vaccine formulation, and infant weight, cumulative exposure of infants to mercury from thimerosal during the first 6 months of life may exceed EPA guidelines.May 01, 2001

Pubmed Data : Pediatrics. 2001 May;107(5):1147-54. PMID: 11331700
Article Published Date : May 01, 2001
Study Type : Human Study
Additional Links
Diseases : Infant Chemical Exposures, Mercury Poisoning
Problem Substances : Thimerosal
[+]

A meta-analysis reveals that thimerosal containing vaccines significantly increase the risk of neurodevelopmental disorders.Aug 01, 2006

Pubmed Data : Neuro Endocrinol Lett. 2006 Aug;27(4):401-13. PMID: 16807526
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Diseases : Ataxia: Cerebellar, Autism, Autism Spectrum Disorders, Mental Retardation, Personality Disorder: Borderline, Speech Disorders
Problem Substances : Thimerosal
[+]

A subpopulation of eight individuals from four of the families showed thimerosal hypersensitivity.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2013 ;2013:801517. Epub 2013 Jun 9. PMID: 23843785
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Mitochondrial Dysfunction , Oxidative Stress
Problem Substances : Thimerosal
[+]

Administration of thimerosal-containing vaccines in the United States resulted in a significant number of children developing neurodevelopmental disorders.Nov 01, 2004

Pubmed Data : Int J Toxicol. 2004 Nov-Dec;23(6):369-76. PMID: 15764492
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Thimerosal
[+]

Adverse events following immunization with vaccines containing adjuvants.Jun 30, 2013

Pubmed Data : Immunol Res. 2013 Jul ;56(2-3):299-303. PMID: 23576057
Article Published Date : Jun 30, 2013
Study Type : Human Study
Additional Links
Diseases : Vaccine-induced Toxicity
Problem Substances : Vaccine Adjuvants
[+]

Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration.Nov 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inorg Biochem. 2009 Nov;103(11):1555-62. Epub 2009 Aug 20. PMID: 19740540
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Diseases : Gulf War Syndrome
Additional Keywords : Adjuvant Toxicity
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum hydroxide-induced macrophagic myofasciitis (MMF) associated with vaccination has been reported. Nov 01, 2011

Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1457-63. Epub 2011 Aug 22. PMID: 22099155
Article Published Date : Nov 01, 2011
Study Type : Human Study
Additional Links
Diseases : Macrophagic myofasciitis
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Aluminum vaccine adjuvants appear to be contributing to the rising prevalence of autism.Oct 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1489-99. Epub 2011 Aug 23. PMID: 22099159
Article Published Date : Oct 31, 2011
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Autism Spectrum Disorders
Additional Keywords : Diseases that are Linked
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Vaccine Adjuvants
[+]

Aluminum vaccine adjuvants appear to contribute to the rising prevalence of autism.Nov 01, 2011

Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1489-99. Epub 2011 Aug 23. PMID: 22099159
Article Published Date : Nov 01, 2011
Study Type : Human Study
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Immunotoxic, Neurotoxic
[+]

Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum.Mar 31, 2013

Pubmed Data : Expert Rev Clin Immunol. 2013 Apr ;9(4):361-73. PMID: 23557271
Article Published Date : Mar 31, 2013
Study Type : Human Study
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Autoimmune Diseases, Vaccine-induced Toxicity
Problem Substances : Vaccine Adjuvants
Adverse Pharmacological Actions : Immunotoxic, Inflammatory
[+]

Boys vaccinated as neonates had threefold greater odds for autism diagnosis compared to boys never vaccinated or vaccinated after the first month of life. Dec 31, 2009

Pubmed Data : J Toxicol Environ Health A. 2010 ;73(24):1665-77. PMID: 21058170
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

Children with autism were twice as likely as non-autistic controls to be born from mothers who had Rh incompatibilities with the developing fetus during pregnancy. Apr 30, 2007

Pubmed Data : J Matern Fetal Neonatal Med. 2007 May ;20(5):385-90. PMID: 17674242
Article Published Date : Apr 30, 2007
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Genomic Variation, Increased Risk, Rh-negative
Problem Substances : Thimerosal
[+]

Coinciding with the largest increase of thimerosal in vaccines given to infants in America, the rates of Kawasaki's Disease increased.Dec 31, 2007

Pubmed Data : Curr Med Chem. 2008 ;15(28):3000-10. PMID: 19075648
Article Published Date : Dec 31, 2007
Study Type : Review
Additional Links
Diseases : Kawasaki Disease, Mercury Poisoning, Vaccine-induced Toxicity
Additional Keywords : Risk Factors
Problem Substances : Thimerosal
[+]

Coinciding with the largest increase of thimerosal in vaccines given to infants in America, the rates of Kawasaki's Disease increased.Dec 31, 2007

Pubmed Data : Curr Med Chem. 2008 ;15(28):3000-10. PMID: 19075648
Article Published Date : Dec 31, 2007
Study Type : Human Study
Additional Links
Diseases : Kawasaki Disease, Mercury Poisoning, Vaccine-induced Toxicity
Additional Keywords : Risk Factors
Problem Substances : Thimerosal
[+]

Cultured lymphocytes from autistic children and non-autistic siblings up-regulate heat shock protein RNA in response to thimerosal challenge.Aug 31, 2006

Pubmed Data : Neurotoxicology. 2006 Sep ;27(5):685-92. Epub 2006 Aug 16. PMID: 16870260
Article Published Date : Aug 31, 2006
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Thimerosal
[+]

High exposure to ethylmercury from thimerosal-containing vaccines in the first month of life increases the risk of subsequent development of neurologic development impairment.Dec 31, 1969

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : NONE
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Infant Neurological Development
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

In the present study, intracytoplasmic inclusions were constantly detected in macrophages of the MMF lesions and were shown to contain aluminium by three different methods.Aug 31, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain. 2001 Sep ;124(Pt 9):1821-31. PMID: 11522584
Article Published Date : Aug 31, 2001
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Macrophagic myofasciitis
Additional Keywords : Biopersistence
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B, Vaccination: Tetanus
Problem Substances : Aluminum Hydroxide
[+]

In this reanalysis data shows that a statistically significant link appears between blood mercury levels and autistic disorder in children.Oct 31, 2007

Pubmed Data : J Child Neurol. 2007 Nov ;22(11):1308-11. PMID: 18006963
Article Published Date : Oct 31, 2007
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Elevated Hg Body Burden
Problem Substances : Mercury, Thimerosal
[+]

Increased organic mercury exposure from Thimerosal-containing hepatitis B vaccines could lead to an increased risk of obesity diagnosis.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Am J Med Sci. 2016 Jul ;8(7):297-306. PMID: 27583238
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Diseases : Obesity
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Obesogenic
[+]

Increasing organic Hg exposure from Thimerosal-containing vaccines increased the subsequent risk of pervasive developmental disorder diagnosis.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Trace Elem Res. 2015 Feb ;163(1-2):28-38. Epub 2014 Nov 11. PMID: 25382662
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: Haemophilus Influenzae
Problem Substances : Thimerosal
[+]

Long-term persistence of vaccine-derived aluminum hydroxide within the body assessed by MMF is associated with cognitive dysfunction.Oct 31, 2009

Pubmed Data : J Inorg Biochem. 2009 Nov ;103(11):1571-8. Epub 2009 Aug 20. PMID: 19748679
Article Published Date : Oct 31, 2009
Study Type : Human Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Macrophagic myofasciitis
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
[+]

Macrophagic myofasciitis in children is a localized reaction to vaccination.May 31, 2008

Pubmed Data : J Child Neurol. 2008 Jun ;23(6):614-9. Epub 2008 Feb 15. PMID: 18281624
Article Published Date : May 31, 2008
Study Type : Human Study
Additional Links
Diseases : Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Mercury exposure from thimerosal containing childhood vaccines raised the subsequent risk of atypical autism diagnosis.Jun 30, 2017

Pubmed Data : J Trace Elem Med Biol. 2017 Jul ;42:18-24. Epub 2017 Mar 9. PMID: 28595786
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

Mercury exposure from thimerosal containing childhood vaccines raised the subsequent risk of diagnosis of emotional disturbances.Jan 18, 2017

Pubmed Data : Brain Inj. 2017 Jan 19:1-7. Epub 2017 Jan 19. PMID: 28102704
Article Published Date : Jan 18, 2017
Study Type : Human Study
Additional Links
Diseases : Mercury Poisoning
Additional Keywords : Increased Risk
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Mercury exposure from thimerosal is significantly associated with the ACSDs of ASD, TD, and ADD/ADHD.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2017 Jan-Mar;15(1):1559325817690849. Epub 2017 Mar 16. PMID: 28539852
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder, Attention Deficit Disorder with Hyperactivity, Autism
Problem Substances : Mercury, Thimerosal
[+]

Mercury levels are 1.9 times higher in subjects diagnosed with autism spectrum disorders.Jan 01, 2010

Pubmed Data : Acta Neurobiol Exp (Wars). 2010;70(2):177-86. PMID: 20628441
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Mothers receiving thimerosal via Rho(D) immune globulin injection saw a significantly higher rate of autism in the children exposed to mercury in utero. Mar 31, 2008

Pubmed Data : Neuro Endocrinol Lett. 2008 Apr ;29(2):272-80. PMID: 18404135
Article Published Date : Mar 31, 2008
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Developmental Disorder: Children, Neurodevelopmental Disorders
Additional Keywords : Rh-negative, Risk Factors
Problem Substances : Thimerosal
[+]

Organic-Hg exposure from thimerosal-containing hepatitis B vaccine led to an increased risk of neurodevelopmental disorder diagnosis.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2014 Sep ;11(9):9156-70. Epub 2014 Sep 5. PMID: 25198681
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Neurodevelopmental Disorders
Additional Keywords : Increased Risk
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trop Med. 2011 ;2011:706304. Epub 2011 May 5. PMID: 21760811
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Infant Mortality , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis, Vaccination: Tetanus, Vaccinaton: Diptheria
Problem Substances : Adjuvant, Aluminum Hydroxide, Vaccine Adjuvants
[+]

The occurrence of neurodevelopmental disorders following thimerosal-containing childhood vaccines does not appear to be coincidental.Mar 31, 2003

Pubmed Data : Pediatr Rehabil. 2003 Apr-Jun;6(2):97-102. PMID: 14534046
Article Published Date : Mar 31, 2003
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Thimerosal
[+]

The vaccine adjuvant squalene in anthrax vaccines given to soldiers in the Gulf War resulted in the formation of antibodies to squalene which are associated with Gulf War Syndrome.Feb 01, 2011

Pubmed Data : Neuropharmacology. 2011 Feb-Mar;60(2-3):252-8. Epub 2010 Sep 22. PMID: 12127050
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Diseases : Anthrax, Gulf War Syndrome
Anti Therapeutic Actions : Vaccination: All, Vaccination: Anthrax
Problem Substances : Squalene, Adjuvant
[+]

The vaccines containing the adjuvant aluminium hydroxide may trigger macrophagic myofasciitis in some patients.Dec 31, 2014

Pubmed Data : Rheumatol Int. 2015 Jan ;35(1):189-92. Epub 2014 Jun 13. PMID: 24923906
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

There is an association between neurodevelopmental disorders and thimerosal-containing vaccines.Jun 01, 2003

Pubmed Data : Exp Biol Med (Maywood). 2003 Jun;228(6):660-4. PMID: 12773696
Article Published Date : Jun 01, 2003
Study Type : Human Study
Additional Links
Diseases : Autism, Mental Retardation, Neurodevelopmental Disorders
Problem Substances : Thimerosal
[+]

There is evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Neurodegener. 2013 ;2(1):25. Epub 2013 Dec 19. PMID: 24354891
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Mercury Poisoning, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Mercury, Thimerosal
[+]

These results provide a neurobiological substrate for brain dysfunction in aluminum hydroxide adjuvant-induced macrophagic myofasciitis patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(6):e0128353. Epub 2015 Jun 1. PMID: 26030650
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Thimerosal containing vaccines may cause atopy in children. Feb 01, 1999

Pubmed Data : Contact Dermatitis. 1999 Feb;40(2):94-7. PMID: 10048654
Article Published Date : Feb 01, 1999
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis, Atopic Disease, Atopic Hypersensitivity, Vaccine-induced Toxicity
Problem Substances : Thimerosal
[+]

This study found a significant increase in neurodevelopmental delays related to the combined exposure to methylmercury and ethylmercury.Jan 06, 2016

Pubmed Data : Environ Res. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26774584
Article Published Date : Jan 06, 2016
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Additional Keywords : Toxic Substance Synergy
Problem Substances : Mercury, Thimerosal
[+]

This study presents the first systematic estimation of ASIA incidence and expands the knowledge on this pathology.Jan 31, 2015

Pubmed Data : Immunol Res. 2015 Feb ;61(1-2):90-6. PMID: 25381482
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
Problem Substances : Vaccine Adjuvants
[+]

This study provides new evidence to confirm a significant relationship between exposure to thimerosal and increased diagnosis for delays in development.Jul 08, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Epidemiol Glob Health. 2015 Jul 9. Epub 2015 Jul 9. PMID: 26166425
Article Published Date : Jul 08, 2015
Study Type : Human Study
Additional Links
Diseases : Developmental Disorder: Children
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

This study provides suggestive evidence of an association between thimerosal and neurodevelopmental outcomes.Mar 13, 2018

Pubmed Data : Int J Hyg Environ Health. 2018 Mar 14. Epub 2018 Mar 14. PMID: 29573974
Article Published Date : Mar 13, 2018
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Anti Therapeutic Actions : Vaccination: Haemophilus Influenzae
Problem Substances : Thimerosal
[+]

This study reveals that the risk of autism significantly decreased with reductions in mercury exposure from thimerosal containing childhood vaccines.Dec 28, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2016 Dec 29 ;22:5196-5202. Epub 2016 Dec 29. PMID: 28031551
Article Published Date : Dec 28, 2016
Study Type : Human Study
Additional Links
Diseases : Autism
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Problem Substances : Thimerosal
[+]

This study shows that autistic children had significantly reduced excretion levels of mercury via hair than the control group. Jun 30, 2003

Pubmed Data : Int J Toxicol. 2003 Jul-Aug;22(4):277-85. PMID: 12933322
Article Published Date : Jun 30, 2003
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Detoxification: Impaired
Additional Keywords : Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

This study supports an association between increasing exposure from thimerosal containing childhood vaccines and the subsequent risk of specific delays in development among males and females.Sep 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Am J Med Sci. 2014 Oct ;6(10):519-31. PMID: 25489565
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Neurodevelopmental Disorders
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV).May 10, 2015

Pubmed Data : Clin Exp Rheumatol. 2015 May 11. Epub 2015 May 11. PMID: 25962455
Article Published Date : May 10, 2015
Study Type : Human Study
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
Problem Substances : Vaccine Adjuvants
Adverse Pharmacological Actions : Immunotoxic, Inflammatory
[+]

Vaccines with Thimerosal led to more adverse events in this study. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pediatr Infect Dis J. 2015 Jan ;34(1):79-83. PMID: 25036048
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Vaccine-induced Toxicity
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

Findings suggest that the epidemiological link between environmental mercury exposure and an increased risk of developing autism may be mediated through mitochondrial dysfunction.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2015 ;2015:573701. Epub 2015 Jan 21. PMID: 25688267
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Mitochondrial Dysfunction , Oxidative Stress
Additional Keywords : Genomic Variation
Problem Substances : Thimerosal
[+]

Peanut oil stimulates an immune response comparable to that of live measles vaccine. Dec 01, 1996

Pubmed Data : Vaccine. 1996 Dec ;14(17-18):1703-6. PMID: 9032902
Article Published Date : Dec 01, 1996
Study Type : Human In Vitro
Additional Links
Diseases : Hypersensitivity, Vaccine-induced Toxicity
Problem Substances : Peanut Oil/ Lectin, Vaccine Adjuvants
Adverse Pharmacological Actions : Immunoreactive
[+]

These data raises some concern on the widespread use of thimerosal.Dec 31, 2002

Pubmed Data : Arch Toxicol. 2003 Jan ;77(1):50-5. Epub 2002 Nov 6. PMID: 12491041
Article Published Date : Dec 31, 2002
Study Type : Human In Vitro
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Genotoxic
[+]

These results alert about the ex-vivo immunomodulatory effects of thimerosal on dendritic cells.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hum Vaccin Immunother. 2014 ;10(8):2328-35. PMID: 25424939
Article Published Date : Dec 31, 2013
Study Type : Human In Vitro
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Immunotoxic
[+]

These results indicate the genotoxic and cytotoxic effect of thimerosal in cultured human peripheral blood lymphocytes.May 31, 2008

Pubmed Data : Toxicol In Vitro. 2008 Jun ;22(4):927-34. Epub 2008 Feb 1. PMID: 18321677
Article Published Date : May 31, 2008
Study Type : Human In Vitro
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Genotoxic
[+]

Thimerosal at low nanomolar concentrations was able to induce significant cellular toxicity in human neuron and fetal cells.May 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Environ Chem. 2009 Jun ;91(3-4):735-749. Epub 2009 Jun 11. PMID: 24532866
Article Published Date : May 31, 2009
Study Type : Human In Vitro
Additional Links
Problem Substances : Aluminum, Lead, Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal induces antiproliferative properties, apoptosis, and autophagy activation in human Chang conjunctival cells.Jan 31, 2014

Pubmed Data : Graefes Arch Clin Exp Ophthalmol. 2014 Feb ;252(2):275-84. Epub 2014 Jan 3. PMID: 24384799
Article Published Date : Jan 31, 2014
Study Type : Human In Vitro
Additional Links
Diseases : DNA damage
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic
[+]

The pathogenic role of aluminium hydroxide is now recognized by the presence of chronic fatigue syndrome, macrophagic myofasciitis and subcutaneous pseudolymphoma, linked to intramuscular injection of aluminium hydroxide-containing vaccines.Mar 14, 2012

Pubmed Data : J Trace Elem Med Biol. 2012 Mar 14. Epub 2012 Mar 14. PMID: 22425036
Article Published Date : Mar 14, 2012
Study Type : Human: Case Report, Review
Additional Links
Diseases : Chronic Fatigue Syndrome, Macrophagic myofasciitis , Pseudolymphoma
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Immunotoxic
[+]

A case of a 14-year-old girl who developed postural orthostatic tachycardia syndrome with chronic fatigue 2 months following Gardasil vaccination.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Investig Med High Impact Case Rep. 2014 Jan-Mar;2(1):2324709614527812. Epub 2014 Mar 18. PMID: 26425598
Article Published Date : Dec 31, 2013
Study Type : Human: Case Report
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Postural Orthostatic Tachycardia Syndrome
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
Problem Substances : Vaccine Adjuvants
[+]

A case of hypersensitivity reaction, myelodysplastic syndrome and pancytopenia, which developed after an thimerosal-containing tetanus vaccine.Nov 30, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Infect Dev Ctries. 2007 Dec 1 ;1(3):348-9. Epub 2007 Aug 1. PMID: 19734619
Article Published Date : Nov 30, 2007
Study Type : Human: Case Report
Additional Links
Diseases : Myelodysplastic Syndrome
Anti Therapeutic Actions : Vaccination: Tetanus
Problem Substances : Thimerosal
[+]

A case report of bilateral deafness two days following influenza vaccination.Aug 16, 2018

Pubmed Data : Hum Vaccin Immunother. 2018 Aug 17. Epub 2018 Aug 17. PMID: 30118641
Article Published Date : Aug 16, 2018
Study Type : Human: Case Report
Additional Links
Diseases : Deafness: Sudden
Anti Therapeutic Actions : Vaccination: Influenza
Problem Substances : Thimerosal
[+]

A series of case studies demonstrate that thimerosal exposure is a major contributing factor to the pathogenesis of autism spectrum disorders.May 15, 2007

Pubmed Data : J Toxicol Environ Health A. 2007 May 15;70(10):837-51. PMID: 17454560
Article Published Date : May 15, 2007
Study Type : Human: Case Report
Additional Links
Diseases : Autism Spectrum Disorders, Mercury Poisoning, Neurodegenerative Diseases
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

A sudden onset of a pseudo-neurological syndrome after HPV-16/18 AS04-adjuvated vaccine.Nov 30, 2014

Pubmed Data : Immunol Res. 2014 Dec ;60(2-3):236-46. PMID: 25388965
Article Published Date : Nov 30, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
Problem Substances : Vaccine Adjuvants
[+]

Central nervous system disease in patients with macrophagic myofasciitis.Apr 30, 2001

Pubmed Data : Brain. 2001 May ;124(Pt 5):974-83. PMID: 11335699
Article Published Date : Apr 30, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Central Nervous System Diseases, Macrophagic myofasciitis
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Systemic allergic contact dermatitis after formaldehyde-containing influenza vaccination.Aug 31, 2015

Pubmed Data : J Cutan Med Surg. 2015 Sep-Oct;19(5):504-6. Epub 2015 Apr 15. PMID: 25876644
Article Published Date : Aug 31, 2015
Study Type : Human: Case Report
Additional Links
Diseases : Dermatitis, Formaldehyde Toxicity, Vaccine-induced Toxicity
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Influenza
Problem Substances : Aspartame, Formaldehyde, Thimerosal
[+]

Thimerosal toxicity can lead to total limbal stem cell failure with secondary corneal vascularization and opacification.Jun 30, 2007

Pubmed Data : Eye Contact Lens. 2007 Jul ;33(4):196-8. PMID: 17630628
Article Published Date : Jun 30, 2007
Study Type : Human: Case Report
Additional Links
Diseases : Mercury Poisoning
Problem Substances : Thimerosal
[+]

This report provides further documentation for a causal association linking the HBV vaccine with lichen planus.Dec 31, 2001

Pubmed Data : Dermatology. 2002 ;205(2):166-8. PMID: 12218234
Article Published Date : Dec 31, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Lichen Planus
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

A dose of 250 mg/kg/day of boric acid is associated with severe developmental toxicity in rabbits. Dec 01, 1996

Pubmed Data : Fundam Appl Toxicol. 1996 Dec;34(2):176-87. PMID: 8954748
Article Published Date : Dec 01, 1996
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

A gender-selective toxicity of thimerosal was observed; this finding is relevant to autism spectrum diagnosis prevalence among males and females.Feb 28, 2009

Pubmed Data : Exp Toxicol Pathol. 2009 Mar ;61(2):133-6. Epub 2008 Sep 3. PMID: 18771903
Article Published Date : Feb 28, 2009
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Thimerosal
[+]

Alhydrogel injected at low dose in mouse muscle may selectively induce long-term Al cerebral accumulation and neurotoxic effects.Nov 27, 2016

Pubmed Data : Toxicology. 2016 Nov 28. Epub 2016 Nov 28. PMID: 27908630
Article Published Date : Nov 27, 2016
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Alpha lipoic acid may protect against mercurial-induced abnormal behaviours.Feb 22, 2018

Pubmed Data : Neurotoxicol Teratol. 2018 Feb 23. Epub 2018 Feb 23. PMID: 29481853
Article Published Date : Feb 22, 2018
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Autism, Neurodevelopmental Disorders
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Thimerosal
[+]

Alum induces a Sjögren’s syndrome-like disorder in mice.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Exp Rheumatol. 2014 Mar-Apr;32(2):251-5. Epub 2014 Apr 9. PMID: 24739520
Article Published Date : Feb 28, 2014
Study Type : Animal Study
Additional Links
Diseases : Sjogren's Syndrome, Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminium-adjuvanted vaccines transiently increase aluminium levels in murine brain tissue.Mar 31, 1992

Pubmed Data : Pharmacol Toxicol. 1992 Apr ;70(4):278-80. PMID: 1608913
Article Published Date : Mar 31, 1992
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminum adjuvants can impair social behaviour if applied in the early period of postnatal development.Nov 20, 2017

Pubmed Data : J Inorg Biochem. 2017 Nov 21. Epub 2017 Nov 21. PMID: 29221615
Article Published Date : Nov 20, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Social Behavior
Problem Substances : Aluminum Hydroxide
[+]

Aluminum adjuvants linked to Gulf War illness induces motor neuron death in mice. Jan 01, 2007

Pubmed Data : Neuromolecular Med. 2007;9(1):83-100. PMID: 17114826
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Gulf War Syndrome, Vaccine-induced Toxicity
Additional Keywords : Adjuvant Toxicity
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum based adjuvants causeed cell death and the subsequent release of host cell DNA, which acts as a potent endogenous immunostimulatory signal mediating alum adjuvant activity.Jul 31, 2011

Pubmed Data : Nat Med. 2011 Aug ;17(8):996-1002. Epub 2011 Jul 17. PMID: 21765404
Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Pharmacological Actions : Apoptotic
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide
[+]

Aluminum hydroxide poisoning results in hematoxicity.Jan 05, 2000

Pubmed Data : Toxicol Lett. 2000 Jan 5;111(3):235-42. PMID: 10643868
Article Published Date : Jan 05, 2000
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Hematoxic
[+]

An extract of Juniperus communis possesses useful anti-arthritic activity.Jan 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:381-392. Epub 2016 Dec 21. PMID: 28012393
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Juniper
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Freund adjuvant
[+]

An oral route of administration for mercury is not comparable to an Intramuscular delivery.Dec 29, 2004

Pubmed Data : Toxicol Lett. 2004 Dec 30 ;154(3):183-9. PMID: 15501610
Article Published Date : Dec 29, 2004
Study Type : Animal Study
Additional Links
Diseases : Mercury Poisoning
Additional Keywords : Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

Boric acid adversely effects early processes in embryogenesis. May 01, 2002

Pubmed Data : Reprod Toxicol. 2002 May-Jun;16(3):237-43. PMID: 12128096
Article Published Date : May 01, 2002
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid adversely effects embryonic development and mortality in rats. Jan 01, 1998

Pubmed Data : Biol Trace Elem Res. 1998;66(1-3):373-94. PMID: 10050931
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid enhances the growth of a cancer cell line in mice. Aug 13, 2001

Pubmed Data : Toxicology. 2001 Aug 13;165(1):1-11. PMID: 11551427
Article Published Date : Aug 13, 2001
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid exhibits estrogen-like effects in vivo. Feb 01, 2008

Pubmed Data : Biol Trace Elem Res. 2008 Feb;121(2):160-70. Epub 2007 Oct 18. PMID: 17943231
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid exhibits teratogenicity (birth defect). Apr 15, 2007

Pubmed Data : Toxicol Appl Pharmacol. 2007 Apr 15;220(2):178-85. Epub 2007 Jan 12. PMID: 17320131
Article Published Date : Apr 15, 2007
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid exhibits testicular toxicity in male rats - Article 2. Oct 01, 2000

Pubmed Data : J Toxicol Sci. 2000 Oct;25 Spec No:223-32. PMID: 11349447
Article Published Date : Oct 01, 2000
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid exhibits testicular toxicity in male rats. Oct 01, 2000

Pubmed Data : J Toxicol Sci. 2000 Oct;25 Spec No:233-9. PMID: 11349449
Article Published Date : Oct 01, 2000
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid exhibits toxicity in trout and zebrafish embryos. Jan 01, 1998

Pubmed Data : Biol Trace Elem Res. 1998;66(1-3):261-70. PMID: 10050924
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid in combination with hyperthermia leads to skeletal defects in rat embryos. Jun 01, 2005

Pubmed Data : Birth Defects Res B Dev Reprod Toxicol. 2005 Jun;74(3):268-76. PMID: 15954087
Article Published Date : Jun 01, 2005
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid induces oxidative stress and effects survivorship in the larvae of the wax moth. Sep 01, 2007

Pubmed Data : Arch Insect Biochem Physiol. 2007 Sep;66(1):23-31. PMID: 17694562
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid is associated with developmental toxicity in mice, rats and rabbits. Nov 01, 1994

Pubmed Data : Environ Health Perspect. 1994 Nov;102 Suppl 7:107-12. PMID: 7889869
Article Published Date : Nov 01, 1994
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid is capable of generating male reproductive toxicities in rats. Aug 01, 1999

Pubmed Data : J Toxicol Sci. 1999 Aug;24(3):199-208. PMID: 10478334
Article Published Date : Aug 01, 1999
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid is used as an insecticide against adult mosquitoes - Article 2. Sep 01, 2006

Pubmed Data : J Am Mosq Control Assoc. 2006 Sep;22(3):497-500. PMID: 17067052
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid is used as an insecticide against adult mosquitoes. Oct 01, 2003

Pubmed Data : J Econ Entomol. 2003 Oct;96(5):1559-62. PMID: 14650531
Article Published Date : Oct 01, 2003
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid is used as an insecticide against cockroaches - Article 2. Aug 01, 2003

Pubmed Data : J Econ Entomol. 2003 Aug;96(4):1362-6. PMID: 14503613
Article Published Date : Aug 01, 2003
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid is used as an insecticide against cockroaches. Jun 01, 2004

Pubmed Data : J Econ Entomol. 2004 Jun;97(3):1009-16. PMID: 15279285
Article Published Date : Jun 01, 2004
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid leads to developmental toxicity both in the presence of maternal toxicity and below maternally toxic levels in rats. Feb 01, 1992

Pubmed Data : Fundam Appl Toxicol. 1992 Feb;18(2):266-77. PMID: 1601227
Article Published Date : Feb 01, 1992
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid may contribute to developmental toxicity in rats. Aug 01, 1996

Pubmed Data : Fundam Appl Toxicol. 1996 Aug;32(2):179-93. PMID: 8921321
Article Published Date : Aug 01, 1996
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Boric acid-exposed rat embryos show defects in their cervical vertebrae. Jan 01, 2003

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2003 Jan;67(1):59-67. PMID: 12749385
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

Both aluminum hydroxide adjuvant and formaldehyde raise antibody levels when used in vaccines.Apr 12, 2007

Pubmed Data : Vaccine. 2007 Apr 12;25(15):2771-7. Epub 2007 Jan 2. PMID: 17240008
Article Published Date : Apr 12, 2007
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum Hydroxide, Formaldehyde
[+]

Calcium phosphate crystals are involved in rhematic disease.Mar 01, 2009

Pubmed Data : Curr Opin Rheumatol. 2009 Mar;21(2):150-7. PMID: 19339926
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Calcium Phosphate
[+]

Calcium phosphate has been shown to increase preneoplastic lesions in the colons of mice.Dec 07, 2010

Pubmed Data : Br J Nutr. 2010 Dec 7:1-8. Epub 2010 Dec 7. PMID: 21134327
Article Published Date : Dec 07, 2010
Study Type : Animal Study
Additional Links
Problem Substances : Calcium Phosphate
Adverse Pharmacological Actions : Tumorigenic
[+]

Data demonstrates a negative neurodevelopmental impact of perinatal exposure to thimerosal.May 31, 2012

Pubmed Data : Cerebellum. 2012 Jun ;11(2):575-86. PMID: 22015705
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Diseases : Learning disorders, Neurodevelopmental Disorders, Oxidative Stress
Additional Keywords : Ethylmercury
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Embryonic exposure to thimerosal affects early development of serotonergic neurons.Nov 13, 2011

Pubmed Data : Neurosci Lett. 2011 Nov 14 ;505(2):61-4. Epub 2011 Jun 6. PMID: 21669256
Article Published Date : Nov 13, 2011
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

exposure to thimerosal during early postnatal life produces lasting alterations in the densities of brain opioid receptors along with other neuropathological changes, which may disturb brain development.Oct 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurochem Res. 2010 Nov ;35(11):1840-7. Epub 2010 Aug 28. PMID: 20803069
Article Published Date : Oct 31, 2010
Study Type : Animal Study
Additional Links
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Hepatitis B vaccine induces cell death in liver cells and mouse liver. Jan 17, 2012

Pubmed Data : Apoptosis. 2012 Jan 17. Epub 2012 Jan 17. PMID: 22249285
Article Published Date : Jan 17, 2012
Study Type : Animal Study
Additional Links
Diseases : Liver Damage, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Hepatotoxic
[+]

Identification and distribution of mercury species in rat tissues following administration of thimerosal or methylmercury.Oct 31, 2010

Pubmed Data : Arch Toxicol. 2010 Nov ;84(11):891-6. Epub 2010 Apr 13. PMID: 20386881
Article Published Date : Oct 31, 2010
Study Type : Animal Study
Additional Links
Additional Keywords : Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

Immunization with hepatitis B vaccine accelerates SLE-like disease in a murine model.Oct 31, 2014

Pubmed Data : J Autoimmun. 2014 Nov ;54:21-32. Epub 2014 Jul 16. PMID: 25042822
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Anxiety Disorders, Systemic Lupus Erythematosus, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Aluminum Hydroxide
[+]

Induction of autoantibodies by mineral oils considered nontoxic also may have pathogenetic implications in human autoimmune diseases.Apr 01, 2004

Pubmed Data : Toxicol Sci. 2004 Apr;78(2):222-8. Epub 2004 Jan 12. PMID: 14718649
Article Published Date : Apr 01, 2004
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases
Problem Substances : Adjuvant, Freund adjuvant, Hexadecane, Mineral Oil, Squalene
[+]

Infant macaques retained significantly higher levels of elemental mercury in their brain tissue when exposed to thimerosal in infant vaccines versus methylmercury. Jul 31, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2005 Aug ;113(8):1015-21. PMID: 16079072
Article Published Date : Jul 31, 2005
Study Type : Animal Study
Additional Links
Additional Keywords : Elevated Hg Body Burden, Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

Injected formaldehyde and Freund's adjuvant are used to induce experimental arthritis - Article 2.Oct 19, 2010

Pubmed Data : J Ethnopharmacol. 2010 Oct 19. Epub 2010 Oct 19. PMID: 20920569
Article Published Date : Oct 19, 2010
Study Type : Animal Study
Additional Links
Problem Substances : Formaldehyde, Freund adjuvant, Vaccine Adjuvants
Adverse Pharmacological Actions : Inflammatory
[+]

Injected formaldehyde and Freund's adjuvant are used to induce experimental arthritis.Dec 01, 2010

Pubmed Data : J Pharm Pharmacol. 2010 Dec;62(12):1801-6. Epub 2010 Oct 4. PMID: 21054408
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Problem Substances : Formaldehyde, Freund adjuvant
Adverse Pharmacological Actions : Inflammatory
[+]

It was found that ethylmercury caused abnormal neurogenic inflammatory reactions and alterations in the neuroimmune cells.May 09, 2018

Pubmed Data : Drug Chem Toxicol. 2018 May 10:1-11. Epub 2018 May 10. PMID: 29745770
Article Published Date : May 09, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Inflammatory
[+]

Maturational changes in amygdala volume and the binding capacity of an opioid antagonist in the amygdala was significantly altered in infant macaques receiving the vaccine schedule. Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Neurobiol Exp (Wars). 2010 ;70(2):147-64. PMID: 20628439
Article Published Date : Dec 31, 2009
Study Type : Animal Study
Additional Links
Diseases : Amygdala: Damage/Abnormalities, Neurodevelopmental Disorders, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
Problem Substances : Thimerosal
[+]

Neonatal administration of a vaccine preservative, thimerosal, produces lasting impairment of nociception and apparent activation of opioid system in rats.Dec 08, 2009

Pubmed Data : Brain Res. 2009 Dec 8;1301:143-51. Epub 2009 Sep 9. PMID: 19747466
Article Published Date : Dec 08, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Thimerosal
[+]

Neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders. DHEA may protect against mercury-induced neurotoxicity. Oct 21, 2011

Pubmed Data : Neurochem Res. 2011 Oct 21. Epub 2011 Oct 21. PMID: 22015977
Article Published Date : Oct 21, 2011
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Excitotoxicity , Mercury Poisoning, Vaccine-induced Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Our results indicate that thimerosal might directly interact with deiodinases.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Endocr Connect. 2017 Nov ;6(8):741-747. PMID: 29101249
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Problem Substances : Thimerosal
[+]

Repetitive administration of aluminium to neonatal mice in amounts comparable to those to children receive via routine vaccinations result in neurodisruptive effects.Oct 31, 2013

Pubmed Data : J Inorg Biochem. 2013 Nov ;128:237-44. Epub 2013 Jul 19. PMID: 23932735
Article Published Date : Oct 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

Subacute boric acid administration has an adverse effect on rat kidney tissue. Jan 01, 2006

Pubmed Data : Clin Toxicol (Phila). 2006;44(3):249-53. PMID: 16749541
Article Published Date : Jan 01, 2006
Study Type : Animal Study
Additional Links
Problem Substances : Boric Acid
[+]

The antioxidant effect of melatonin revealed in this experiment is based on detoxification rather than common involvement in antioxidant barriers.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Medica (Hradec Kralove). 2015 ;58(1):21-4. PMID: 26454803
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Detoxifier
Problem Substances : Freund adjuvant
[+]

The ethylmercury component of thimerosal was rapidly taken up in the kidney, liver, and mesenterial lymph nodes In mice.Aug 14, 2003

Pubmed Data : Anal Chem. 2003 Aug 15 ;75(16):4120-4. PMID: 14632125
Article Published Date : Aug 14, 2003
Study Type : Animal Study
Additional Links
Diseases : Mercury Poisoning
Problem Substances : Thimerosal
[+]

The injection of n-hexadecane, pristane, incomplete Freund's adjuvant (IFA), or the adjuvant oil squalene results in lupus-related specific autoantibodies in an animal model. Feb 01, 2006

Pubmed Data : Toxicology. 2006 Feb 1;218(2-3):186-96. Epub 2005 Nov 23. PMID: 16309812
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Problem Substances : Freund adjuvant, Hexadecane, Pristane, Squalene, Adjuvant
[+]

The kidney must be considered a potential target for ethylmercury toxicity.Sep 30, 2014

Pubmed Data : Environ Res. 2014 Oct ;134:218-27. Epub 2014 Aug 28. PMID: 25173055
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Renotoxic
[+]

The vaccine ingredient Freund's adjuvant has been used to induce experimental autoimmune encephalomyelitis (an experimental version of multiple sclerosis)Jun 01, 2009

Pubmed Data : Clin Nutr. 2009 Jun;28(3):346-50. Epub 2009 Apr 21. PMID: 19386399
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Multiple Sclerosis, Vaccine-induced Toxicity
Additional Keywords : Plant Extracts
Problem Substances : Freund adjuvant
[+]

The vaccine ingredient Freund's adjuvant has been used to induce monoarticular arthritis in an animal model. Jan 01, 2009

Pubmed Data : Phytother Res. 2009 Jan;23(1):1-5. PMID: 19048609
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Additional Keywords : Plant Extracts, Vaccine Adjuvant
Problem Substances : Freund adjuvant
Adverse Pharmacological Actions : Inflammatory
[+]

The vaccine ingredient Freund's adjuvant is used to induce arthritis in rat experiments - Article 2. Dec 01, 2009

Pubmed Data : J Physiol Pharmacol. 2009 Dec;60(4):147-55. PMID: 20065509
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Additional Keywords : Drug: Indomethacin, Vaccine Adjuvant
Problem Substances : Freund adjuvant
Adverse Pharmacological Actions : Inflammatory
[+]

The vaccine ingredient Freund's adjuvant is used to induce arthritis in rat experiments.Jan 01, 2010

Pubmed Data : J Basic Clin Physiol Pharmacol. 2010;21(1):15-26. PMID: 20506686
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Vaccine-induced Toxicity
Additional Keywords : Plant Extracts, Vaccine Adjuvan
Problem Substances : Freund adjuvant
Adverse Pharmacological Actions : Inflammatory
[+]

There are lasting neuropathological changes in rat brain after intermittent neonatal administration of thimerosal.Jan 01, 2010

Pubmed Data : Folia Neuropathol. 2010 ;48(4):258-69. PMID: 21225508
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Infant Chemical Exposures, Neurodegenerative Diseases, Vaccine-induced Toxicity
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

These findings implicate a genetic influence in autistic disorders and provides a model for investigating thimerosal related neurotoxicity.Aug 31, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2004 Sep ;9(9):833-45. PMID: 15184908
Article Published Date : Aug 31, 2004
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders, Autoimmune Diseases, Neurodevelopmental Disorders
Additional Keywords : Genomic Variation
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

These results indicate that embryonic exposure to thimerosal produces lasting impairment of brain monoaminergic system.Feb 28, 2013

Pubmed Data : Brain Dev. 2013 Mar ;35(3):261-4. Epub 2012 Jun 1. PMID: 22658806
Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal had a proapoptotic effect on primary human lymphocytes at concentrations 100 times less to those contained in the multidose vaccine.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(4):e92705. Epub 2014 Apr 1. PMID: 24690681
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Influenza
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic, Immunotoxic
[+]

Thimerosal induces an instantaneous, complete and long-lasting microtubule interphasic network disassembly in mouse primary oocytes.Aug 31, 2003

Pubmed Data : Biol Cell. 2003 Sep ;95(6):407-14. PMID: 14519558
Article Published Date : Aug 31, 2003
Study Type : Animal Study
Additional Links
Diseases : Mercury Poisoning
Problem Substances : Thimerosal
[+]

Thimerosal induces in genetically susceptible mice a systemic autoimmune syndrome very similar to that seen after treatment with inorganic mercury.Jan 14, 2004

Pubmed Data : Toxicol Appl Pharmacol. 2004 Jan 15 ;194(2):169-79. PMID: 14736497
Article Published Date : Jan 14, 2004
Study Type : Animal Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Immunoreactive
[+]

This report systematically explains pathways possibly involved in thimerosal-induced autistic-like behaviour.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Sci. 2014 Jun ;139(2):452-65. Epub 2014 Mar 27. PMID: 24675092
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Autism, Neurodegenerative Diseases
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

This study proposes the novel hypothesis that abnormalities involving the zinc-metalloprotease-BDNF axis may play a pivotal role in hyperconnectivity and megalencephaly observed in ASD.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Brain. 2014 ;7:64. Epub 2014 Sep 3. PMID: 25182223
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Thimerosal
[+]

This study raised serious concerns about adverse neurodevelopmental disorders such as autism in humans after thimerosal containing vaccines.Oct 31, 2013

Pubmed Data : World J Pediatr. 2013 Nov ;9(4):356-60. Epub 2013 Nov 14. PMID: 24235069
Article Published Date : Oct 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Autism, Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Tween 80 exposure in newborn rats results in disruption of female reproductive organs.Mar 01, 1993

Pubmed Data : Food Chem Toxicol. 1993 Mar;31(3):183-90. PMID: 8473002
Article Published Date : Mar 01, 1993
Study Type : Animal Study
Additional Links
Problem Substances : Adjuvant, Tween 80
Adverse Pharmacological Actions : Carcinogenic, Endocrine Disruptor
[+]

Vaccine adjuvants can contribute to the pathogenesis of autoimmune diseases such as lupus. Aug 01, 2003

Pubmed Data : J Autoimmun. 2003 Aug;21(1):1-9. PMID: 12892730
Article Published Date : Aug 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases, Lupus Erythematosus: Systemic, Vaccine-induced Toxicity
Problem Substances : Adjuvant, Freund adjuvant, Mineral Oil, Pristane, Squalene
Adverse Pharmacological Actions : Immunotoxic
[+]

VAERS had significantly higher ORs than autism following thimerosal containing DTaP vaccines in comparison to thimerosal free DTaP vaccines. Sep 29, 2011

Pubmed Data : Behav Brain Res. 2011 Sep 30 ;223(1):107-18. Epub 2011 Apr 28. PMID: 21549155
Article Published Date : Sep 29, 2011
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
Problem Substances : Thimerosal
[+]

"Hypothesis: is Alzheimer's disease a metal-induced immune disorder?"Feb 28, 1995

Pubmed Data : Neurodegeneration. 1995 Mar ;4(1):107-11. PMID: 7600179
Article Published Date : Feb 28, 1995
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

"Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations."Jan 01, 2012

Pubmed Data : Lupus. 2012 ;21(2):223-30. PMID: 22235057
Article Published Date : Jan 01, 2012
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide, Vaccine Adjuvants
[+]

A comprehensive analysis is included on the comordities of autism and their corresponding analogs due to mercury exposure.Mar 31, 2001

Pubmed Data : Med Hypotheses. 2001 Apr ;56(4):462-71. PMID: 11339848
Article Published Date : Mar 31, 2001
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Mercury Poisoning
Additional Keywords : Elevated Hg Body Burden, Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

A new inflammatory muscle disorder, characterized by a distinctive pathological pattern of macrophagic myofasciitis is emerging in France.Feb 04, 2000

Pubmed Data : Presse Med. 2000 Feb 5 ;29(4):203-8. PMID: 10705901
Article Published Date : Feb 04, 2000
Study Type : Review
Additional Links
Diseases : Macrophagic myofasciitis
Problem Substances : Vaccine Adjuvants
[+]

A review of developmental neurotoxicants and the vulnerable male brain.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Neurobiol Exp (Wars). 2017 ;77(4):269-296. PMID: 29369294
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Problem Substances : Bisphenol A , Organochlorine pesticides, Phthalates, Thimerosal
[+]

A review of medical literature has shown that exposure to organic or inorganic mercury can give rise to the symptoms and traits defining or commonly found in ASD individuals.Dec 31, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2002 ;7 Suppl 2:S42-3. PMID: 12142947
Article Published Date : Dec 31, 2001
Study Type : Review
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Autism Spectrum Disorders
Additional Keywords : Ethylmercury, Genomic Variation, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

A significant correlation exists between the number of pediatric aluminum-adjuvanted vaccines administered and the rate of autism spectrum disorders.Jun 30, 2013

Pubmed Data : Immunol Res. 2013 Jul ;56(2-3):304-16. PMID: 23609067
Article Published Date : Jun 30, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autism Spectrum Disorders
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

A simultaneous exposure to both etHg and meHg might result in enhanced neurotoxic effects in developing mammals.Jul 31, 2013

Pubmed Data : J Appl Toxicol. 2013 Aug ;33(8):700-11. Epub 2013 Feb 11. PMID: 23401210
Article Published Date : Jul 31, 2013
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity
Additional Keywords : Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
[+]

Adjuvants for human vaccines-current status, problems and future prospects.Sep 30, 1995

Pubmed Data : Vaccine. 1995 Oct ;13(14):1263-76. PMID: 8585280
Article Published Date : Sep 30, 1995
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

All these models support the concept of ASIA, as the Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants. Dec 31, 2012

Pubmed Data : Curr Med Chem. 2013 ;20(32):4030-6. PMID: 23992328
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Autoimmune Diseases, Inflammation
Problem Substances : Vaccine Adjuvants
[+]

Aluminium has been demonstrated to impact the CNS at every level, including by changing gene expression.Dec 31, 2013

Pubmed Data : Immunotherapy. 2014 ;6(10):1055-71. PMID: 25428645
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Neurodegenerative Diseases
Additional Keywords : aluminum, aluminum toxicity, Autoimmune Diseases, Gene Expression, Neurodegenerative diseases, Vaccine Adjuvants
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminium hydroxide and calcium phosphate adjuvants have a immunotoxic and haemolytic effects.Jan 01, 1993

Pubmed Data : Vaccine. 1993;11(9):914-8. PMID: 8212836
Article Published Date : Jan 01, 1993
Study Type : In Vitro Study
Additional Links
Additional Keywords : Adjuvant Toxicity
Problem Substances : Aluminum Hydroxide, Calcium Phosphate
Adverse Pharmacological Actions : Hemolytic, Immunosuppressive, Immunotoxic
[+]

Aluminum inclusion macrophagic myofasciitis: a recently identified condition.Oct 31, 2003

Pubmed Data : Immunol Allergy Clin North Am. 2003 Nov ;23(4):699-712. PMID: 14753387
Article Published Date : Oct 31, 2003
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis
Problem Substances : Aluminum Hydroxide
[+]

ASIA or Shoenfeld's syndrome-an autoimmune syndrome induced by adjuvants.Jun 30, 2013

Pubmed Data : Rom J Intern Med. 2013 Jul-Dec;51(3-4):131-4. PMID: 24620624
Article Published Date : Jun 30, 2013
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)
Problem Substances : Vaccine Adjuvants
[+]

Boric acid and Diphenhydramine (Benadryl) exhibit embryotoxic activity. Oct 01, 2008

Pubmed Data : Toxicol Sci. 2008 Oct;105(2):342-50. Epub 2008 Jun 30. PMID: 18593728
Article Published Date : Oct 01, 2008
Study Type : In Vitro Study
Additional Links
Problem Substances : Boric Acid, Diphenhydramine
[+]

Both aluminium hydroxide and calcium phosphate exert local tissue irritating effects through damaging macrophages and increasing inflammation.Aug 01, 1997

Pubmed Data : Vaccine. 1997 Aug-Sep;15(12-13):1364-71. PMID: 9302746
Article Published Date : Aug 01, 1997
Study Type : In Vitro Study
Additional Links
Problem Substances : Aluminum Hydroxide, Calcium Phosphate
Adverse Pharmacological Actions : Cytotoxic, Inflammatory, Irritant
[+]

Both organic and inorganic species of mercury can affect the human immune system.Oct 04, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Lett. 2010 Oct 5 ;198(2):182-90. Epub 2010 Jun 26. PMID: 20600710
Article Published Date : Oct 04, 2010
Study Type : In Vitro Study
Additional Links
Additional Keywords : Ethylmercury, Methylmercury
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Immunoreactive
[+]

Brain translocation of aluminum particles is linked to a trojan horse mechanism previously described for infectious particles.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2015 ;6:4. Epub 2015 Feb 5. PMID: 25699008
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Macrophagic myofasciitis
Additional Keywords : Biopersistence, Genomic Variation, Gulf War Syndrome, Risk Factors
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Clinical features in patients with long-lasting macrophagic myofasciitis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2014 ;5:230. Epub 2014 Nov 28. PMID: 25506338
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis
Problem Substances : Aluminum Hydroxide
[+]

Compounds commonly used as preservatives in US licensed vaccine/biological preparations exhibit significant toxicity and may not comply with the US Code of Federal Regulations for preservatives.Apr 28, 2010

Pubmed Data : Med Sci Monit. 2010 Apr 28;16(5):SR21-7. PMID: 20424565
Article Published Date : Apr 28, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Vaccine-induced Toxicity
Problem Substances : 2-phenoxyethanol, Adjuvant, Benzethonium chloride, Phenol, Thimerosal
[+]

Culmination of the research that examines the effects of thimerosal in humans indicates that it is a poison at minute levels with a plethora of deleterious consequences.Apr 14, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Chim Acta. 2015 Apr 15 ;444:212-220. Epub 2015 Feb 21. PMID: 25708367
Article Published Date : Apr 14, 2015
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders, Tic Disorders
Problem Substances : Thimerosal
[+]

Decreased tubulin tyrosination represents a neuron-specific early marker of mercury toxicity associated with impaired neurite outgrowth.Sep 30, 2007

Pubmed Data : Toxicol In Vitro. 2007 Oct ;21(7):1258-61. Epub 2007 Aug 14. PMID: 17553660
Article Published Date : Sep 30, 2007
Study Type : In Vitro Study
Additional Links
Diseases : Mercury Poisoning
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Dendritic cells are exquisitely sensitive to Thimerosal.Jun 30, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2006 Jul ;114(7):1083-91. PMID: 16835063
Article Published Date : Jun 30, 2006
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
[+]

Ethylmercury dose-dependently increased the production of reactive oxygen species.Aug 09, 2016

Pubmed Data : Toxicol Sci. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27511942
Article Published Date : Aug 09, 2016
Study Type : In Vitro Study
Additional Links
Additional Keywords : Dose Response
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Oxidant
[+]

Febrile reaction was noted in approximately 60% of the children given alum-adjuvanted whole virion inactivated H5N1 vaccine. Jan 01, 2011

Pubmed Data : Yakugaku Zasshi. 2011 ;131(12):1723-31. PMID: 22129866
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Febrile Seizures, Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Five food preservatives exhibit genotoxicity in a plant model.Jan 10, 2007

Pubmed Data : Mutat Res. 2007 Jan 10;626(1-2):4-14. Epub 2006 Sep 26. PMID: 17005441
Article Published Date : Jan 10, 2007
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Problem Substances : Boric Acid, Citric acid, Food Preservatives, Potassium citrate, Sodium Benzoate, Sodium Citrate
Adverse Pharmacological Actions : Genotoxic
[+]

Freund's adjuvant is a widely used immunostimulant in vaccines that is associated with inflammation and tissue destruction. Jan 01, 2005

Pubmed Data : ILAR J. 2005;46(3):280-93. PMID: 15953835
Article Published Date : Jan 01, 2005
Study Type : Commentary
Additional Links
Additional Keywords : Adjuvant-Induced Injury, Adjuvant Toxicity, Vaccine Adjuvant
Problem Substances : Freund adjuvant
[+]

High susceptibility of neural stem cells to methylmercury toxicity: effects on cell survival and neuronal differentiation.Mar 31, 2006

Pubmed Data : J Neurochem. 2006 Apr ;97(1):69-78. Epub 2006 Mar 8. PMID: 16524380
Article Published Date : Mar 31, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Neurodevelopmental Disorders
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Neural Stem Cell, Vaccine Adjuvant
Problem Substances : Thimerosal
[+]

Human adjuvant-related syndrome or autoimmune/inflammatory syndrome induced by adjuvants.Aug 31, 2015

Pubmed Data : Lupus. 2015 Sep ;24(10):1012-8. Epub 2015 Mar 25. PMID: 25813870
Article Published Date : Aug 31, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)
Problem Substances : Vaccine Adjuvants
[+]

In 2004 the risk of autism among African American children vaccinated before the age of 2 years was 340% that of those vaccinated later.Sep 30, 2014

Pubmed Data : Indian J Med Ethics. 2014 Oct-Dec;11(4):218-22. PMID: 25377033
Article Published Date : Sep 30, 2014
Study Type : Commentary
Additional Links
Diseases : Autism, Vaccine-induced Toxicity
Problem Substances : Thimerosal
[+]

In the presence of a favourable genetic background, many autoimmune/inflammatory responses can be triggered by adjuvants.Nov 30, 2014

Pubmed Data : Immunol Res. 2014 Dec ;60(2-3):366-75. PMID: 25395340
Article Published Date : Nov 30, 2014
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation, Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Infant and fetal tissue appears to be more vulnerable to some toxic effects of mercury than older children and adults.Jul 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2013 Aug ;10(8):3771-800. Epub 2013 Aug 20. PMID: 23965928
Article Published Date : Jul 31, 2013
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Vaccine-induced Toxicity
Problem Substances : Thimerosal
[+]

Lactic acid triggers, in vitro, thiomersal to degrade protein in the presence of PLGA microspheres.Mar 31, 2004

Pubmed Data : Int J Pharm. 2004 Apr 1 ;273(1-2):1-8. PMID: 15010124
Article Published Date : Mar 31, 2004
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
[+]

Low-dose mercury exposure in early life: relevance of thimerosal to fetuses, newborns and infants.Dec 31, 2012

Pubmed Data : Curr Med Chem. 2013 ;20(32):4060-9. PMID: 23992327
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity
Additional Keywords : Risk Factors
Problem Substances : Thimerosal
[+]

Low-dose thimerosal is still used in infants vaccines.Aug 31, 2018

Pubmed Data : J Trace Elem Med Biol. 2018 Sep ;49:134-139. Epub 2018 May 17. PMID: 29895363
Article Published Date : Aug 31, 2018
Study Type : Review
Additional Links
Problem Substances : Thimerosal
[+]

Luteolin may be useful in preventing mercury-induced toxicity.Sep 30, 2010

Pubmed Data : Int J Immunopathol Pharmacol. 2010 Oct-Dec;23(4):1015-20. PMID: 21244751
Article Published Date : Sep 30, 2010
Study Type : In Vitro Study
Additional Links
Substances : Luteolin
Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors
Problem Substances : Thimerosal
[+]

Macrophagic myofasciitis has been reported following vaccination and is attributed to the aluminium hydroxide.Oct 31, 2009

Pubmed Data : Lupus. 2009 Nov ;18(13):1213-6. PMID: 19880571
Article Published Date : Oct 31, 2009
Study Type : Review
Additional Links
Diseases : Myopathies, Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Mercury is able to trigger a pathogenic process which results in autoimmunity and coronary artery lesions as observed in Kawasaki syndrome.Aug 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean Circ J. 2013 Sep ;43(9):581-91. PMID: 24174958
Article Published Date : Aug 31, 2013
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Kawasaki Disease
Additional Keywords : Risk Factors
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Immunoreactive
[+]

More research attention has been given to EtHg and findings have showed a solid link with neurotoxic effects in humans.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2015 Feb ;12(2):1295-313. Epub 2015 Jan 23. PMID: 25625408
Article Published Date : Jan 31, 2015
Study Type : Review
Additional Links
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Thimerosal
[+]

Natural immunomodulators represent a potentially important way of blocking or partly restoring the immunosuppression of toxins such as mercury.Oct 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2012 Nov ;4(11):1301-8. Epub 2012 Nov 9. PMID: 23202317
Article Published Date : Oct 31, 2012
Study Type : Review
Additional Links
Substances : Resveratrol, Stilbenes, Vitamin C
Pharmacological Actions : Cytoprotective
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Immunotoxic
[+]

Neurological adverse events associated with vaccination.May 31, 2002

Pubmed Data : Curr Opin Neurol. 2002 Jun ;15(3):333-8. PMID: 12045734
Article Published Date : May 31, 2002
Study Type : Review
Additional Links
Diseases : Autism, Guillain-Barre Syndrome, Multiple Sclerosis, New Variant Creutzfeldt-Jakob Disease, Vaccine-induced Toxicity
Additional Keywords : Adverse Events, Vaccine Contaminants
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Thimerosal
[+]

Organic mercury compounds seem to induce the apoptotic cascade in neurons following low-level exposure.Sep 30, 2015

Pubmed Data : J Trace Elem Med Biol. 2015 Oct ;32:200-8. Epub 2015 Jul 15. PMID: 26302930
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Oxidation by thimerosal increases calcium levels in renal tubular cells.Aug 31, 2003

Pubmed Data : Pharmacol Toxicol. 2003 Sep ;93(3):123-7. PMID: 12969436
Article Published Date : Aug 31, 2003
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Oxidant
[+]

Peroxiredoxin 2 (PRDX2), an antioxidant enzyme, is under-expressed in Down syndrome fetal brains.Jun 30, 2003

Pubmed Data : Cell Mol Life Sci. 2003 Jul ;60(7):1513-23. PMID: 12943237
Article Published Date : Jun 30, 2003
Study Type : In Vitro Study
Additional Links
Diseases : Down Syndrome, Oxidative Stress
Additional Keywords : Increased Risk
Problem Substances : Thimerosal
[+]

Recent studies implicate a web of mechanisms in the development of vaccine adjuvant-induced autoimmune diseases.Sep 30, 2015

Pubmed Data : Autoimmun Rev. 2015 Oct ;14(10):880-8. Epub 2015 May 29. PMID: 26031899
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Autoimmune Diseases, Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Repetitive doses of thimerosal leads to neurobehavioral deteriorations in autoimmune susceptible mice.Sep 30, 2005

Pubmed Data : Neuro Endocrinol Lett. 2005 Oct ;26(5):439-46. PMID: 16264412
Article Published Date : Sep 30, 2005
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Inflammation
Problem Substances : Thimerosal
[+]

Research on autism spectrum disorder (ASD) and mercury reveals conflicts of interest and the need for transparency in autism research.Nov 07, 2017

Pubmed Data : Sci Eng Ethics. 2017 Nov 8. Epub 2017 Nov 8. PMID: 29119411
Article Published Date : Nov 07, 2017
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Mercury Poisoning
Additional Keywords : Conflict Of Interest (COI)
Problem Substances : Mercury, Thimerosal
[+]

Review: Thimerosal use represents a medical crisis.Dec 01, 2007

Pubmed Data : J Toxicol Environ Health B Crit Rev. 2007 Dec;10(8):575-96. PMID: 18049924
Article Published Date : Dec 01, 2007
Study Type : Review
Additional Links
Diseases : Mercury Poisoning, Vaccine-induced Toxicity
Problem Substances : Thimerosal
[+]

Scientific research does not support rejecting the link between the neurodevelopmental disorder of autism and toxic exposures.Dec 31, 2009

Pubmed Data : Acta Neurobiol Exp (Wars). 2010 ;70(2):165-76. PMID: 20628440
Article Published Date : Dec 31, 2009
Study Type : Commentary
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Heavy Metals, Mercury, Thimerosal
[+]

Skin lightening creams and soaps are sources of mercury.Jul 15, 2016

Pubmed Data : Int J Hyg Environ Health. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27451074
Article Published Date : Jul 15, 2016
Study Type : Commentary
Additional Links
Anti Therapeutic Actions : Vaccination: Influenza
Problem Substances : Cosmetics, Mercury, Thimerosal
[+]

The aim of this review was to focus on Sjogren's Syndrome and its possible development following vaccine or silicone exposure.May 31, 2014

Pubmed Data : J Autoimmun. 2014 Jun ;51:10-6. Epub 2014 Apr 26. PMID: 24774584
Article Published Date : May 31, 2014
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation, Sjogren's Syndrome, vaccine injury
Problem Substances : Vaccine Adjuvants
[+]

The CDC's current stance that Thimerosal is safe and that there is no relationship to autism was based on six flawed studies coauthored and sponsored by the CDC.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2014 ;2014:247218. Epub 2014 Jun 4. PMID: 24995277
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Additional Keywords : Conflict Of Interest (COI)
Problem Substances : Thimerosal
[+]

The cytotoxic action of thimerosal was greatly augmented when the cells suffered oxidative stress induced by H2O2.Sep 30, 2004

Pubmed Data : Toxicol In Vitro. 2004 Oct ;18(5):563-9. PMID: 15251173
Article Published Date : Sep 30, 2004
Study Type : In Vitro Study
Additional Links
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic
[+]

The discrepancy in studies reporting no relationship between Hg and ASD suggests a bias indicative of a conflict of interest.Oct 26, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Eng Ethics. 2015 Oct 27. Epub 2015 Oct 27. PMID: 26507205
Article Published Date : Oct 26, 2015
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Conflict Of Interest (COI)
Problem Substances : Mercury, Thimerosal
[+]

The Druckrey-Küpfmüller equation describes well the dose-response characteristics of organic mercury induced neurotoxic effects.Mar 01, 2016

Pubmed Data : Toxicology. 2016 Mar 2. Epub 2016 Mar 2. PMID: 26945727
Article Published Date : Mar 01, 2016
Study Type : Review
Additional Links
Additional Keywords : Dose Response
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

The emergence of ASIA syndrome is associated with individual genetic predisposition.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lupus. 2017 Jan 1:961203316686406. Epub 2017 Jan 1. PMID: 28059022
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)
Additional Keywords : Genomic Variation
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Vaccine Adjuvants
[+]

The FDA announced in 1999 that infants who had multiple vaccines with thimerosal may have been exposed to cumulative Hg in excess of federal safety guidelines.Sep 30, 2001

Pubmed Data : Neurotoxicology. 2001 Oct ;22(5):691-7. PMID: 11770890
Article Published Date : Sep 30, 2001
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity
Problem Substances : Thimerosal
[+]

The Minamata Convention on Hg has sanctioned the inequitable distribution of thimerosal by specifically exempting TCVs from regulation.Sep 30, 2014

Pubmed Data : Indian J Med Ethics. 2014 Oct-Dec;11(4):206-18. Epub 2014 Apr 11. PMID: 25101548
Article Published Date : Sep 30, 2014
Study Type : Review
Additional Links
Problem Substances : Thimerosal
[+]

The overwhelming preponderance of the evidence favours acceptance that Hg exposure is capable of causing some autism spectrum disorders.Sep 30, 2008

Pubmed Data : Indian J Med Res. 2008 Oct ;128(4):383-411. PMID: 19106436
Article Published Date : Sep 30, 2008
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Mercury Poisoning
Problem Substances : Mercury, Thimerosal
[+]

The preponderance of the evidence indicates that mercury exposure is causal or contributory in autism spectrum disorders.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trace Elem Med Biol. 2016 Sep ;37:8-24. Epub 2016 Jun 2. PMID: 27473827
Article Published Date : Aug 31, 2016
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Thimerosal
[+]

The reduction of MT-1 mRNA level by thiosalicylate may affect the proliferation of C8-B4 cells.Jun 29, 2009

Pubmed Data : Toxicology. 2009 Jun 30 ;261(1-2):25-32. Epub 2009 Apr 19. PMID: 19386279
Article Published Date : Jun 29, 2009
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
[+]

The results of this study suggest that ethylmercury is a mitochondrial toxin in human astrocytes. Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2012 ;2012:373678. Epub 2012 Jun 28. PMID: 22811707
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage, Excitotoxicity , Oxidative Stress
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic, Excitotoxic
[+]

The results underscore the importance of PLD signaling in mercury-induced endothelial dysfunctions ultimately leading to cardiovascular diseases.Dec 31, 2006

Pubmed Data : Int J Toxicol. 2007 Jan-Feb;26(1):57-69. PMID: 17365148
Article Published Date : Dec 31, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Endothelial Damage, Oxidative Stress
Problem Substances : Mercury, Thimerosal
[+]

The risk of aluminum vaccine adjuvants may be greatly underestimated. May 16, 2011

Pubmed Data : Curr Med Chem. 2011 May 16. Epub 2011 May 16. PMID: 21568886
Article Published Date : May 16, 2011
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Immunotoxic
[+]

The vaccine adjuvant thimerosal is cytotoxic to neuronal cells.Dec 01, 2005

Pubmed Data : Int J Mol Med. 2005 Dec;16(6):971-7. PMID: 16273274
Article Published Date : Dec 01, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Autism
Problem Substances : Thimerosal
[+]

The vaccine adjuvant thimerosal is cytotoxic to T cells.Aug 01, 2002

Pubmed Data : Genes Immun. 2002 Aug;3(5):270-8. PMID: 12140745
Article Published Date : Aug 01, 2002
Study Type : In Vitro Study
Additional Links
Diseases : Immune Disorders: Low Immune Function, Oxidative Stress
Problem Substances : Thimerosal
[+]

There appears to be little difference in the neurotoxicity of MeHg and EthylHg.Dec 31, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2002 ;7 Suppl 2:S40-1. PMID: 12142946
Article Published Date : Dec 31, 2001
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Developmental Disorder: Children, Mercury Poisoning, Neurotoxicity
Additional Keywords : Ethylmercury, Methylmercury
Problem Substances : Thimerosal
[+]

There are several case reports of autoimmune diseases following vaccines.Sep 30, 2015

Pubmed Data : Pharmacol Res. 2015 Oct ;100:190-209. Epub 2015 Aug 12. PMID: 26275795
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

There is a biological basis for mercury-induced autism spectrum disorders and the sexual dimorphism associated with disease prevalence.Jan 01, 2010

Pubmed Data : Acta Neurobiol Exp (Wars). 2010;70(2):209-26. PMID: 20628444
Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Problem Substances : Thimerosal
[+]

There was a high rate of sensitization to thimerosal in Thai patients.Aug 31, 2007

Pubmed Data : J Med Assoc Thai. 2007 Sep ;90(9):1775-9. PMID: 17957918
Article Published Date : Aug 31, 2007
Study Type : Review
Additional Links
Problem Substances : Thimerosal
[+]

Thimerosal and autism? A plausible hypothesis that should not be dismissed.Dec 31, 2003

Pubmed Data : Med Hypotheses. 2004 ;62(5):788-94. PMID: 15082108
Article Published Date : Dec 31, 2003
Study Type : Commentary
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Thimerosal
[+]

Thimerosal and mercuric ions influence neurotransmission by interacting with GABA and NMDA receptor complexes in live neurons.Nov 30, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Physiol Pharmacol. 2010 Dec ;61(6):753-8. PMID: 21224507
Article Published Date : Nov 30, 2010
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal at 30 microM induced an apoptotic change in membranes of almost all living cells. Feb 28, 2005

Pubmed Data : Toxicol In Vitro. 2005 Mar ;19(2):191-8. PMID: 15649632
Article Published Date : Feb 28, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Mercury Poisoning
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic, Cytotoxic
[+]

Thimerosal at concentrations relevant for infants exposure in vaccines is toxic to cultured human brain cells and to laboratory animals. May 31, 2011

Pubmed Data : Neurochem Res. 2011 Jun ;36(6):927-38. Epub 2011 Feb 25. PMID: 21350943
Article Published Date : May 31, 2011
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal decreases TRPV1 activity by oxidation of extracellular sulfhydryl residues.Oct 20, 2004

Pubmed Data : Neurosci Lett. 2004 Oct 21 ;369(3):250-5. PMID: 15464274
Article Published Date : Oct 20, 2004
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
[+]

Thimerosal demonstrated a higher cytotoxicity on renal cells than other metals studied. Nov 30, 2007

Pubmed Data : J Toxicol Environ Health A. 2007 Dec ;70(24):2092-5. PMID: 18049999
Article Published Date : Nov 30, 2007
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Renotoxic
[+]

Thimerosal exerts cytotoxic actions on cerebellar granule neurons dissociated from 2-week-old rats and its potency is similar to methylmercury.Jan 14, 2004

Pubmed Data : Toxicology. 2004 Jan 15 ;195(1):77-84. PMID: 14698570
Article Published Date : Jan 14, 2004
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal exposure is associated with adverse neurodevelopmental outcomes. Nov 02, 2016

Pubmed Data : Environ Res. 2016 Nov 3 ;152:280-293. Epub 2016 Aug 3. PMID: 27816865
Article Published Date : Nov 02, 2016
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal exposure of dendritic cells led to the depletion of intracellular glutathione.Jan 31, 2007

Pubmed Data : J Leukoc Biol. 2007 Feb ;81(2):474-82. Epub 2006 Aug 1. PMID: 17079650
Article Published Date : Jan 31, 2007
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
[+]

Thimerosal induced cell death in SH-SY5Y cells and cortical neurons.Sep 21, 2016

Pubmed Data : Toxicol Sci. 2016 Sep 22. Epub 2016 Sep 22. PMID: 27660204
Article Published Date : Sep 21, 2016
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro.Nov 30, 2015

Pubmed Data : Environ Toxicol. 2015 Dec ;30(12):1423-33. Epub 2014 Jun 18. PMID: 24942245
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Renotoxic
[+]

Thimerosal induces DNA breaks, caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts.Jul 31, 2003

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Sci. 2003 Aug ;74(2):361-8. Epub 2003 Aug 28. PMID: 12773768
Article Published Date : Jul 31, 2003
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic, Neurotoxic
[+]

Thimerosal induces S phase arrest and causes apoptosis in C2C12 myoblast cells.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(11):e49064. Epub 2012 Nov 7. PMID: 23145070
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Apoptotic
[+]

Thimerosal interacts with the cysteine residue C214 in the S3 segment of KCNQ1, leading to a change of its gating properties.Mar 14, 2002

Pubmed Data : J Membr Biol. 2002 Mar 15 ;186(2):89-100. PMID: 11944086
Article Published Date : Mar 14, 2002
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Oxidant
[+]

Thimerosal reduced SNAP-25 mRNA levels to 73% and 69% of the control levels. Sep 26, 2016

Pubmed Data : Toxicology. 2016 Sep 27. Epub 2016 Aug 27. PMID: 27693314
Article Published Date : Sep 26, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal seems to induce FAK tyrosine phosphorylation and cytoskeletal changes by ROS generation.Dec 15, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochim Biophys Acta. 2002 Dec 16 ;1593(1):9-15. PMID: 12431779
Article Published Date : Dec 15, 2002
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Oxidant
[+]

Thiol reagent thimerosal-induced Ca2+ mobilization in isolated guinea pig cochlear outer hair cells.May 31, 2000

Pubmed Data : Zhonghua Er Bi Yan Hou Ke Za Zhi. 2000 Jun ;35(3):192-5. PMID: 12768775
Article Published Date : May 31, 2000
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal
[+]

Thiomersal and ethylmercury could significantly inhibit the thioredoxin system in vitro. Jul 31, 2015

Pubmed Data : Toxicol Appl Pharmacol. 2015 Aug 1 ;286(3):216-23. Epub 2015 May 14. PMID: 25981166
Article Published Date : Jul 31, 2015
Study Type : In Vitro Study
Additional Links
Additional Keywords : Ethylmercury
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

This finding might help understanding the autoimmune potential of mercurial compounds. Feb 29, 2016

Pubmed Data : Arch Toxicol. 2016 Mar ;90(3):543-50. Epub 2015 Feb 22. PMID: 25701957
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Autoimmune Diseases
Problem Substances : Mercury, Thimerosal
[+]

This finding might help understanding the autoimmune potential of mercurial compounds. Feb 29, 2016

Pubmed Data : Arch Toxicol. 2016 Mar ;90(3):543-50. Epub 2015 Feb 22. PMID: 25701957
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Autoimmune Diseases
Problem Substances : Mercury, Thimerosal
[+]

This review concludes that chronic adjuvant stimulation may lead to lymphoma. Jan 31, 2015

Pubmed Data : Immunol Res. 2015 Feb ;61(1-2):79-89. PMID: 25582758
Article Published Date : Jan 31, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation, Lymphoma
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

This reviews the current data regarding the role of adjuvants in the pathogenesis of immune mediated diseases.Jan 31, 2011

Pubmed Data : J Autoimmun. 2011 Feb ;36(1):4-8. Epub 2010 Aug 13. PMID: 20708902
Article Published Date : Jan 31, 2011
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation
Problem Substances : Vaccine Adjuvants
[+]

This study investigated the cellular response to thimerosal toxicity including a very profound decrease in intracellular glutathione levels. Dec 31, 2004

Pubmed Data : Neurotoxicology. 2005 Jan ;26(1):1-8. PMID: 15527868
Article Published Date : Dec 31, 2004
Study Type : In Vitro Study
Additional Links
Diseases : Neurotoxicity
Additional Keywords : Glutathione Metabolism
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Cytotoxicity
[+]

This study shows that inhibition of methionine synthase(MS) activity by ethanol, lead, mercury, aluminum and thimerosal suggesting that it may be an important target of neurodevelopmental toxins.Mar 31, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2004 Apr ;9(4):358-70. PMID: 14745455
Article Published Date : Mar 31, 2004
Study Type : In Vitro Study
Additional Links
Diseases : Attention Deficit Disorder, Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Aluminum, Ethanol, Lead, Thimerosal
Adverse Pharmacological Actions : Hypermethylation
[+]

Uptake of particulate vaccine adjuvants (e.g. nanoparticle polystyrene) by dendritic cells activates the NALP3 inflammasome.Jan 20, 2009

Pubmed Data : Proc Natl Acad Sci U S A. 2009 Jan 20 ;106(3):870-5. Epub 2009 Jan 12. PMID: 19139407
Article Published Date : Jan 20, 2009
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Interleukin-1 beta downregulation
Anti Therapeutic Actions : Nanotechnology
Problem Substances : Polystyrene nanoparticles, Vaccine Adjuvants
Adverse Pharmacological Actions : Immunoreactive, Immunotoxic
[+]

Vaccination with adjuvants may be responsible for a number of disorders. Feb 01, 2003

Pubmed Data : Rev Neurol (Paris). 2003 Feb;159(2):162-4. PMID: 12660567
Article Published Date : Feb 01, 2003
Study Type : Commentary
Additional Links
Diseases : Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Syndrome, Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide
[+]

Very early thiol oxidation induced by thimerosal exerts a much more dramatic effect on resumption on meiosis than any pharmacological manipulation.Jul 31, 2003

Pubmed Data : Mol Reprod Dev. 2003 Aug ;65(4):454-61. PMID: 12840819
Article Published Date : Jul 31, 2003
Study Type : In Vitro Study
Additional Links
Problem Substances : Thimerosal

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