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Zolpidem (trade name Ambien)
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Quick Summary: Current access displays 2 out of 24 associated Diseases
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View the Evidence: Problem Substances
Hypnotic drugs increase the risk of skin cancer.
Click here to see the entire article
Pubmed Data
: J Sleep Res. 2008 Sep;17(3):245-50. PMID:
18844818
Article Published Date
: Sep 01, 2008
Study Type
: Meta Analysis
Additional Links
Diseases
:
Melanoma : CK(168) : AC(87)
,
Skin Cancer : CK(438) : AC(171)
Problem Substances
:
Eszopiclone : CK(60) : AC(3)
,
Hypnotic Drugs : CK(134) : AC(14)
,
Ramelteon : CK(50) : AC(3)
,
Zaleplon : CK(60) : AC(3)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Carcinogenic : CK(871) : AC(110)
There is a greater incidence of depression with hypnotic use than with placebo.
Click here to see the entire article
Pubmed Data
: BMC Psychiatry. 2007;7:42. Epub 2007 Aug 21. PMID:
17711589
Article Published Date
: Jan 01, 2007
Study Type
: Meta Analysis
Additional Links
Diseases
:
Depression: Unipolar : CK(631) : AC(79)
Problem Substances
:
Eszopiclone : CK(60) : AC(3)
,
Hypnotic Drugs : CK(134) : AC(14)
,
Ramelteon : CK(50) : AC(3)
,
Zaleplon : CK(60) : AC(3)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Delirium, nightmares and hallucinations have been reported as a consequence of treatment with zolpidem.
Click here to see the entire article
Pubmed Data
: Clin Neuropharmacol. 2000 Jan-Feb;23(1):54-8. PMID:
10682233
Article Published Date
: Jan 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Delirium: Drug-Induced : CK(26) : AC(6)
,
Night Terror : CK(158) : AC(1)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Hallucinogenic : CK(30) : AC(3)
Hypnotic drug use is associated with significantly increased risk of infection.
Click here to see the entire article
Pubmed Data
: J Clin Sleep Med. 2009 Aug 15;5(4):377-83. PMID:
19968019
Article Published Date
: Aug 15, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Bacterial Infections and Mycoses : CK(126) : AC(51)
Problem Substances
:
Eszopiclone : CK(60) : AC(3)
,
Hypnotic Drugs : CK(134) : AC(14)
,
Ramelteon : CK(50) : AC(3)
,
Zaleplon : CK(60) : AC(3)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Immunosuppressive : CK(143) : AC(23)
Hypnotic drugs have been demonstrated to significantly impair driving performance.
Click here to see the entire article
Pubmed Data
: J Sleep Res. 2009 Dec;18(4):387-96. Epub 2009 Jun 22. PMID:
19552733
Article Published Date
: Dec 01, 2009
Study Type
: Human Study
Additional Links
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Hypnotic drugs may have residual effects in driving habits which could lead to risky behavior.
Click here to see the entire article
Pubmed Data
: Psychopharmacology (Berl). 2009 Dec;207(3):461-7. Epub 2009 Oct 2. PMID:
19798483
Article Published Date
: Dec 01, 2009
Study Type
: Human Study
Additional Links
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
,
Zopiclone : CK(10) : AC(1)
Adverse Pharmacological Actions
:
Hypnotic : CK(10) : AC(1)
Increased risk of adverse pregnancy outcomes in women receiving zolpidem during pregnancy.
Click here to see the entire article
Pubmed Data
: Clin Pharmacol Ther. 2010 Sep;88(3):369-74. Epub 2010 Aug 4. PMID:
20686480
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Pregnancy Complications : CK(166) : AC(19)
,
Prenatal Chemical Exposures : CK(324) : AC(86)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Teratogenic : CK(317) : AC(59)
Receiving hypnotic prescriptions was associated with greater than threefold increased hazards of death even when prescribed<18 pills/year.
Click here to see the entire article
Article Publish Status
: This is a free article.
Click here to read the entire article.
Pubmed Data
: BMJ Open. 2012 ;2(1):e000850. Epub 2012 Feb 27. PMID:
22371848
Article Published Date
: Jan 01, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Drug-Induced Toxicity : CK(538) : AC(78)
,
Mortality: All-Cause : CK(644) : AC(55)
Problem Substances
:
Barbiturates : CK(0) : AC(0)
,
Benzodiazepines : CK(0) : AC(0)
,
Eszopiclone : CK(60) : AC(3)
,
Hypnotic Drugs : CK(134) : AC(14)
,
Sedative antihistamines : CK(0) : AC(0)
,
Temazepam : CK(0) : AC(0)
,
Zaleplon : CK(60) : AC(3)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Some psychotic reactions, such as visual or hypnagogic hallucinations, have been reported to be associated with zolpidem use.
Click here to see the entire article
Pubmed Data
: J Toxicol Clin Toxicol. 2003;41(6):869-72. PMID:
14677799
Article Published Date
: Jan 01, 2003
Study Type
: Human Study
Additional Links
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Hallucinogenic : CK(30) : AC(3)
There are a number of adverse effects associated with zolpidem ingestion as reported to Texas poison centers.
Click here to see the entire article
Pubmed Data
: Hum Exp Toxicol. 2009 Aug;28(8):505-9. Epub 2009 Sep 8. PMID:
19737812
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
There is evidence that zolpidem may be abused and cause dependency.
Click here to see the entire article
Pubmed Data
: Br J Clin Pharmacol. 2007 Aug;64(2):198-209. Epub 2007 Feb 23. PMID:
17324242
Article Published Date
: Aug 01, 2007
Study Type
: Human Study
Additional Links
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Addictive : CK(24) : AC(4)
Zolipidem induced Nocturnal Sleep-Related Eating Disorder (NSRED) has been reported in a male patient.
Click here to see the entire article
Pubmed Data
: Int J Eat Disord. 2009 May;42(4):385-6. PMID:
19107832
Article Published Date
: May 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Eating Disorders: Nocturnal Eating : CK(11) : AC(2)
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Zolpidem can interfere with sleep-dependent memory consolidation.
Click here to see the entire article
Pubmed Data
: J Sleep Res. 2010 Mar;19(1 Pt 2):157-64. Epub 2009 Aug 13. PMID:
19682231
Article Published Date
: Mar 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Learning disorders : CK(154) : AC(36)
,
Memory Disorders: Drug-Induced : CK(74) : AC(12)
,
Memory Loss : CK(113) : AC(32)
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Amnesiac : CK(24) : AC(6)
Zolpidem may cause dependency among users.
Click here to see the entire article
Pubmed Data
: J Psychopharmacol. 2003 Mar;17(1):131-5. PMID:
12680751
Article Published Date
: Mar 01, 2003
Study Type
: Human Study
Additional Links
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Addictive : CK(24) : AC(4)
Zolpidem, Meprobamate and calcium channel antagonists are associated with increased risk of falls in hospitalized elderly patients.
Click here to see the entire article
Pubmed Data
: Drugs Aging. 2009;26(10):847-52. PMID:
19761277
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Elderly: Age Specific Diseases : CK(423) : AC(37)
,
Hip Fracture : CK(1783) : AC(21)
Problem Substances
:
Calcium Channel Antagonists : CK(20) : AC(2)
,
Meprobamate : CK(10) : AC(1)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Zolpidem-associated hallucinations may be stimulated or amplified by the use of serotonin reuptake inhibitors.
Click here to see the entire article
Pubmed Data
: J Toxicol Clin Toxicol. 1998;36(3):195-203. PMID:
9656974
Article Published Date
: Jan 01, 1998
Study Type
: Human Study
Additional Links
Additional Keywords
:
Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)
Problem Substances
:
Selective Serotonin Reuptake Inhibitors (SSRIs) : CK(74) : AC(9)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Hallucinogenic : CK(30) : AC(3)
Compulsive activity combined with anterograde amnesia may be associated with the use of zolpidem.
Click here to see the entire article
Pubmed Data
: Clin Toxicol (Phila). 2007;45(2):179-81. PMID:
17364638
Article Published Date
: Jan 01, 2007
Study Type
: Commentary
Additional Links
Diseases
:
Amnesia: Drug-Induced : CK(13) : AC(4)
,
Compulsive Behavior: Drug-Induced : CK(1) : AC(1)
,
Drug-Induced Toxicity : CK(538) : AC(78)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Amnesiac : CK(24) : AC(6)
Delirium associated with zolpidem use has been reported.
Click here to see the entire article
Pubmed Data
: Ann Pharmacother. 2001 Dec;35(12):1562-4. PMID:
11793620
Article Published Date
: Dec 01, 2001
Study Type
: Commentary
Additional Links
Diseases
:
Delirium: Drug-Induced : CK(26) : AC(6)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Seizure following sudden zolpidem withdrawal has been reported.
Click here to see the entire article
Pubmed Data
: Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):539-40. Epub 2006 Sep 6. PMID:
16950552
Article Published Date
: Mar 30, 2007
Study Type
: Commentary
Additional Links
Diseases
:
Seizures : CK(122) : AC(28)
,
Seizures: Drug-Induced : CK(26) : AC(6)
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Addictive : CK(24) : AC(4)
Zolpidem abuse, dependence and withdrawal reactions have been reported.
Click here to see the entire article
Pubmed Data
: Rev Med Liege. 2009 Jul-Aug;64(7-8):407-8. PMID:
19777922
Article Published Date
: Jul 01, 2009
Study Type
: Commentary
Additional Links
Diseases
:
Seizures: Drug-Induced : CK(26) : AC(6)
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Zolpidem has been reported to cause transient global amnesia-like episodes.
Click here to see the entire article
Pubmed Data
: J Patient Saf. 2009 Mar;5(1):32-4. PMID:
19920437
Article Published Date
: Mar 01, 2009
Study Type
: Commentary
Additional Links
Diseases
:
Amnesia: Drug-Induced : CK(13) : AC(4)
Problem Substances
:
Hypnotic Drugs : CK(134) : AC(14)
,
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Amnesiac : CK(24) : AC(6)
Zolpidem use has been linked to amnestic sleep related eating disorders.
Click here to see the entire article
Pubmed Data
: J Clin Sleep Med. 2007 Oct 15;3(6):637-8. PMID:
17993047
Article Published Date
: Oct 15, 2007
Study Type
: Commentary
Additional Links
Diseases
:
Eating Disorders : CK(23) : AC(3)
,
Eating Disorders: Nocturnal Eating : CK(11) : AC(2)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions
:
Amnesiac : CK(24) : AC(6)
Zolpidem-induced distortion in visual perception has been reported.
Click here to see the entire article
Pubmed Data
: Ann Pharmacother. 2003 May;37(5):683-6. PMID:
12708947
Article Published Date
: May 01, 2003
Study Type
: Commentary
Additional Links
Diseases
:
Visual Disturbances: Drug-Induced : CK(1) : AC(1)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Zolpidem-induced psychosis has been reported.
Click here to see the entire article
Pubmed Data
: Ann Clin Psychiatry. 1996 Jun;8(2):89-91. PMID:
8807033
Article Published Date
: Jun 01, 1996
Study Type
: Commentary
Additional Links
Diseases
:
Psychoses : CK(12) : AC(3)
,
Psychoses: Drug-Induced : CK(4) : AC(2)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
Zolpidem-induced sleepwalking, sleep related eating disorder, and sleep-driving have been reported.
Click here to see the entire article
Pubmed Data
: J Clin Sleep Med. 2009 Oct 15;5(5):471-6. PMID:
19961034
Article Published Date
: Oct 15, 2009
Study Type
: Commentary
Additional Links
Diseases
:
Somnambulism : CK(1) : AC(1)
Problem Substances
:
Zolpidem (trade name Ambien) : CK(199) : AC(25)
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 indicating it may contribute to Melanoma, Skin Cancer, and Depression: Unipolar){kind=link}