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Latest Abstracts Imported from Pubmed.gov, Rated & Indexed

Synergetic effect of Andrographis paniculata polysaccharide on diabetic nephropathy with andrographolide.

Article Published Date : Nov 30, 2012
Study Type : Animal Study
Additional Links
Substances : Andrographis : CK(93) : AC(38), Andrographolide : CK(10) : AC(9)
Diseases : Diabetic Nephropathy : CK(707) : AC(277)
Pharmacological Actions : Renoprotective : CK(2404) : AC(1075)
Additional Keywords : Natural Substance Synergy : CK(1094) : AC(506)

Andrographolide inhibits osteopontin expression and breast tumor growth through down regulation of PI3 kinase/Akt signaling pathway.

Article Published Date : Aug 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Andrographis : CK(93) : AC(38)
Diseases : Breast Cancer : CK(6327) : AC(2272)
Pharmacological Actions : Anti-Angiogenic : CK(347) : AC(234), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore.

Article Published Date : Oct 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Andrographolide : CK(10) : AC(9)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Apoptotic : CK(6986) : AC(5304)

Andrographis paniculata extract prevents development of murine colitis.

Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Andrographis : CK(93) : AC(38)
Diseases : Inflammatory Bowel Diseases : CK(1994) : AC(540), Ulcerative Colitis : CK(666) : AC(196)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interferon Gamma Reducer : CK(58) : AC(24), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Andrographolide protects against LPS-induced acute lung injury by inactivation of NF-κB.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographis : CK(93) : AC(38)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073), Lung Injury: Acute : CK(321) : AC(159)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Andrographolide protects against cigarette smoke-induced lung inflammation through activation of heme oxygenase-1.

Article Published Date : Apr 30, 2013
Study Type : Animal Study
Additional Links
Substances : Andrographolide : CK(10) : AC(9)
Diseases : Lung Injury: Smoke-Induced : CK(71) : AC(33)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Heme oxygenase-1 up-regulation : CK(624) : AC(373)

Andrographolide prevented type 1 diabetes by maintaining Th1/Th2/Th17 homeostasis.

Article Published Date : Jul 31, 2013
Study Type : Animal Study
Additional Links
Substances : Andrographolide : CK(10) : AC(9)
Diseases : Diabetes Mellitus: Type 1 : CK(1605) : AC(471)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hypoglycemic Agents : CK(5366) : AC(1338), Immunomodulatory : CK(4048) : AC(1475), Interferon Gamma Reducer : CK(58) : AC(24), Interleukin-10 upregulation : CK(105) : AC(24), Interleukin-2 Downregulation : CK(123) : AC(51)

Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function.

Article Published Date : Jun 17, 2013
Study Type : In Vitro Study
Additional Links
Substances : Andrographis : CK(93) : AC(38)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

AP-1/IRF-3 targeted anti-inflammatory activity of andrographolide isolated from Andrographis paniculata.

Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Andrographolide : CK(10) : AC(9)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Evaluation of anti-bacterial and anti-oxidant potential of andrographolide and echiodinin.

Article Published Date : Jul 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Andrographis : CK(93) : AC(38), Andrographolide : CK(10) : AC(9)
Diseases : Bacillus subtilis infections : CK(32) : AC(31), Escherichia coli Infections : CK(401) : AC(297), Klebsiella Infections : CK(143) : AC(81), Mycobacterium Infections : CK(167) : AC(84), Pseudomonas aeruginosa : CK(304) : AC(238), Staphylococcus aureus infection : CK(498) : AC(374), Streptococcus Infections : CK(546) : AC(117)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

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